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The map label for this gene is gatR [H]

Identifier: 209396656

GI number: 209396656

Start: 2841292

End: 2842071

Strand: Reverse

Name: gatR [H]

Synonym: ECH74115_3069

Alternate gene names: 209396656

Gene position: 2842071-2841292 (Counterclockwise)

Preceding gene: 209395932

Following gene: 209396353

Centisome position: 51.01

GC content: 46.67

Gene sequence:

>780_bases
ATGACGATGAATTCATTCGAGCGAAGGAATAAGATCATCCAATTAGTGAATGAACAGGGAACCGTGCTTGTTCAGGATCT
GGCGGGAGTATTTGCTGCCTCGGAAGCGACAATCCGTGCCGATTTGCGCTTTCTCGAACAAAAAGGCGTGGTTACGCGCT
TTCATGGCGGTGCGGCGAAAATAATGTCTGGTAATAGTGAAACCGAGACCCAGGAAGTCGGGTTTAAAGAGCGATTTCAG
CTTGCCAGCGCGCCAAAAAACAGAATAGCGCAGGCGGCAGTCAAAATGATCCACGAAGGGATGACCGTTATTCTCGACAG
CGGAAGTACGACAATGCTTATCGCCGAAGGATTAATGACCGCCAAAAATATCACGGTGATTACCAACAGTCTCCCGGCAG
CGTTTGCCCTTTCCGAAAATAAAGACATTACTCTGGTCGTCTGTGGTGGCACGGTCCGCCATAAAACGCGCTCGATGCAT
GGTTCCATTGCCGAGCGTTCATTGCAGGATATTAATGCCGATTTAATGTTTGTCGGTGCTGATGGTATTGATGCGGTTAA
TGGTATTACGACCTTTAATGAAGGTTATTCGATTAGCGGGGCGATGGTCACCGCCGCAAATAAAGTGATTGCCGTTCTCG
ATTCATCGAAATTTAATCGTCGCGGTTTTAATCAGGTACTGCCAATCGAAAAAATTGACATTATTATTACCGATGATGCC
GTGTCAGATGTGGATAAACTGGCATTGCAGAAGACACGGGTAAAATTAATTACGGTGTAG

Upstream 100 bases:

>100_bases
AAACCGCGGGCCAGCGTGATGCTGGCCCGGTATTGTGCAAAACAGATCATTCACCAATGGTCCCCCTTCGTTTACACTAG
CCACAATTGAATATGGGTAA

Downstream 100 bases:

>100_bases
TATTGTTCTGTATGCCGGATAAGGTGTTTACACCGCATCCGGCATTACGGATTCTCCCTGGTTCAAGAGAGAATAGTTTG
ATTAACGCAATAATGGACAA

Product: galactitol utilization operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQ
LASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMH
GSIAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDA
VSDVDKLALQKTRVKLITV

Sequences:

>Translated_259_residues
MTMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQ
LASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMH
GSIAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDA
VSDVDKLALQKTRVKLITV
>Mature_258_residues
TMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQL
ASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHG
SIAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDAV
SDVDKLALQKTRVKLITV

Specific function: Repressor of the gat operon for galacticol transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=37.7952755905512, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789059, Length=256, Percent_Identity=39.0625, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI226510968, Length=256, Percent_Identity=30.859375, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1788069, Length=237, Percent_Identity=32.4894514767932, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787540, Length=259, Percent_Identity=29.7297297297297, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789829, Length=237, Percent_Identity=29.1139240506329, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI87082344, Length=253, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1789170, Length=233, Percent_Identity=28.755364806867, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787063, Length=253, Percent_Identity=25.296442687747, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1790753, Length=261, Percent_Identity=24.904214559387, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790635, Length=242, Percent_Identity=26.8595041322314, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27946; Mature: 27814

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2 ; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAK
CCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCEEE
IMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMT
EECCCCCCHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEEECCHHC
AKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGSIAERSLQDINADLMFVGA
CCCEEEEECCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
DGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDA
CCCCHHCCEEECCCCCEECCEEEEECCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCH
VSDVDKLALQKTRVKLITV
HHHHHHHHHHHHEEEEEEC
>Mature Secondary Structure 
TMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAK
CCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCEEE
IMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMT
EECCCCCCHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCEEEEEECCHHC
AKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGSIAERSLQDINADLMFVGA
CCCEEEEECCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
DGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDA
CCCCHHCCEEECCCCCEECCEEEEECCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCH
VSDVDKLALQKTRVKLITV
HHHHHHHHHHHHEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 7772602; 1661252 [H]