| Definition | Escherichia coli O157:H7 str. EC4115, complete genome. |
|---|---|
| Accession | NC_011353 |
| Length | 5,572,075 |
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The map label for this gene is ygcW [H]
Identifier: 209396374
GI number: 209396374
Start: 1283269
End: 1284051
Strand: Direct
Name: ygcW [H]
Synonym: ECH74115_1271
Alternate gene names: 209396374
Gene position: 1283269-1284051 (Clockwise)
Preceding gene: 209399126
Following gene: 209396689
Centisome position: 23.03
GC content: 42.27
Gene sequence:
>783_bases ATGAGCTTTTCTATTGAAGATTTTTCATTGGATTTTTTTTCATTACATAACAAGGTGGCCATCGTAACTGGGGCCGCGGG TGAGCTGGGGAGAGGCTTATGCTCGGCTCTGGCCAAAGCAGGGGCTAATCTATTGTTGGTTGACATCAAAGAGCCTGATA ATAGATATTTGAAGCATTTAACTCATGAAGGCGTTGAAGTTGAGTTTATGACAATAGACATAACAAAACCTGATGCATCA TGCACCATTATTAATAGGTGTCTGGAGCGTTTCGGTCAGTTAGATATTCTGGTCAATAACGCGGGCGTGTGTAACATTAA TCGTCCTATCGATTTCAATCGAAACGACTGGGATCCGATGATTAATCTCAACCTGAATGCTGCATTCGATATGAGCCAGG CCGCATTGAATATATTTGTCCCGCAAAGAAAAGGGAAAATTATTAATATGTGTTCCGTATTGTCATTTCATGGGGGACGT TGGTCGCCAGGGTATGCGGCGACTAAACATGCTTTAGCGGGGCTGACCAAAGCGTATGCCGATGATTTTGCGGAATATAA TATTCAGATTAATGGTATCGCCCCAGGATATTATGTGAGTGAAATGACCGCTATTATTTATAATAACCCTAAAATAAAAG AGTTAATAAAAGGGCGTATACCGGCTCAACGCTGGGGAAGGGCACAGGATCTTATGGGCGCAATGGTGTTCCTCGCCAGT GCCGCTTCAGATTATGTCAATGGACAACTATTAGTCATTGATGGTGGATATTCAATTCGTTAA
Upstream 100 bases:
>100_bases ATTCATGCTGAGTTTTAATGTTTATATTTTTTTATTGAAATCTAAAAATTACTTAAATTATCCCTTAAATATTACTTACT CATAAGGAGCAATGTGTGAT
Downstream 100 bases:
>100_bases CGATTTTTGGCTGCGTTGAGGTGTTTTGACTGGAAAATGGAGTGGAGAGATTTTGTCATTTCTCCACTTCCGGTACTTCA GGTGGGTATAGTGGTTATTC
Product: 2-deoxy-D-gluconate 3-dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 260; Mature: 259
Protein sequence:
>260_residues MSFSIEDFSLDFFSLHNKVAIVTGAAGELGRGLCSALAKAGANLLLVDIKEPDNRYLKHLTHEGVEVEFMTIDITKPDAS CTIINRCLERFGQLDILVNNAGVCNINRPIDFNRNDWDPMINLNLNAAFDMSQAALNIFVPQRKGKIINMCSVLSFHGGR WSPGYAATKHALAGLTKAYADDFAEYNIQINGIAPGYYVSEMTAIIYNNPKIKELIKGRIPAQRWGRAQDLMGAMVFLAS AASDYVNGQLLVIDGGYSIR
Sequences:
>Translated_260_residues MSFSIEDFSLDFFSLHNKVAIVTGAAGELGRGLCSALAKAGANLLLVDIKEPDNRYLKHLTHEGVEVEFMTIDITKPDAS CTIINRCLERFGQLDILVNNAGVCNINRPIDFNRNDWDPMINLNLNAAFDMSQAALNIFVPQRKGKIINMCSVLSFHGGR WSPGYAATKHALAGLTKAYADDFAEYNIQINGIAPGYYVSEMTAIIYNNPKIKELIKGRIPAQRWGRAQDLMGAMVFLAS AASDYVNGQLLVIDGGYSIR >Mature_259_residues SFSIEDFSLDFFSLHNKVAIVTGAAGELGRGLCSALAKAGANLLLVDIKEPDNRYLKHLTHEGVEVEFMTIDITKPDASC TIINRCLERFGQLDILVNNAGVCNINRPIDFNRNDWDPMINLNLNAAFDMSQAALNIFVPQRKGKIINMCSVLSFHGGRW SPGYAATKHALAGLTKAYADDFAEYNIQINGIAPGYYVSEMTAIIYNNPKIKELIKGRIPAQRWGRAQDLMGAMVFLASA ASDYVNGQLLVIDGGYSIR
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=28.2868525896414, Blast_Score=104, Evalue=7e-23, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=28.1124497991968, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI66933014, Length=259, Percent_Identity=32.046332046332, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=27.710843373494, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=30, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=28.2352941176471, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=25.9259259259259, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=25.5639097744361, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI31542939, Length=191, Percent_Identity=30.8900523560209, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=25.390625, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=24.2914979757085, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI7706318, Length=212, Percent_Identity=27.3584905660377, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=31.3953488372093, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4758504, Length=261, Percent_Identity=24.904214559387, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI20149619, Length=237, Percent_Identity=26.5822784810127, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI4504505, Length=188, Percent_Identity=26.063829787234, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4503301, Length=203, Percent_Identity=23.6453201970443, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=55.2529182879377, Blast_Score=305, Evalue=2e-84, Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=42.8571428571429, Blast_Score=204, Evalue=7e-54, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=37.6518218623482, Blast_Score=167, Evalue=6e-43, Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=33.201581027668, Blast_Score=136, Evalue=2e-33, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=30.327868852459, Blast_Score=135, Evalue=3e-33, Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=28.8065843621399, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=30.2788844621514, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1786812, Length=246, Percent_Identity=25.2032520325203, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=25.3846153846154, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=25.3012048192771, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=26.2096774193548, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=26.5873015873016, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1787526, Length=207, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=30.4, Blast_Score=117, Evalue=5e-27, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=29.8387096774194, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=26.2096774193548, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=28.5714285714286, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=28.8973384030418, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=28.4090909090909, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=30.2681992337165, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=28.8389513108614, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=28.2442748091603, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI72000259, Length=259, Percent_Identity=27.7992277992278, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=27.8625954198473, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=28.9473684210526, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=25.8064516129032, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=25.296442687747, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=27.5862068965517, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=27.7153558052434, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=26.984126984127, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=26.7175572519084, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=26.7924528301887, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=27.8195488721804, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=28.2442748091603, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17568967, Length=188, Percent_Identity=28.1914893617021, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=25.0950570342205, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=25, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=27.5193798449612, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=28.030303030303, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=25.5725190839695, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=27.0992366412214, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI193203115, Length=186, Percent_Identity=26.3440860215054, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI193203117, Length=188, Percent_Identity=26.063829787234, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=25.5208333333333, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=25.6, Blast_Score=82, Evalue=1e-16, Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=27.1794871794872, Blast_Score=80, Evalue=4e-16, Organism=Saccharomyces cerevisiae, GI6323882, Length=247, Percent_Identity=24.2914979757085, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=26.6129032258064, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=28.8617886178862, Blast_Score=114, Evalue=6e-26, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=31.8725099601594, Blast_Score=114, Evalue=9e-26, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=30.3643724696356, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=30.5882352941176, Blast_Score=105, Evalue=4e-23, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=26.1904761904762, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=29.6442687747036, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=28.4046692607004, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=28.125, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=28.125, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI18859837, Length=217, Percent_Identity=28.110599078341, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI221331218, Length=196, Percent_Identity=25.5102040816327, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI24665243, Length=196, Percent_Identity=25.5102040816327, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 28597; Mature: 28466
Theoretical pI: Translated: 6.66; Mature: 6.66
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 5.0 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSFSIEDFSLDFFSLHNKVAIVTGAAGELGRGLCSALAKAGANLLLVDIKEPDNRYLKHL CCCCCCCCCCHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH THEGVEVEFMTIDITKPDASCTIINRCLERFGQLDILVNNAGVCNINRPIDFNRNDWDPM HCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCEEECCCCCCCCCCCCCCE INLNLNAAFDMSQAALNIFVPQRKGKIINMCSVLSFHGGRWSPGYAATKHALAGLTKAYA EEEEECCCCCCCCCEEEEEEECCCCCEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH DDFAEYNIQINGIAPGYYVSEMTAIIYNNPKIKELIKGRIPAQRWGRAQDLMGAMVFLAS HHHHHEEEEEEEECCCHHHHHEEEEEECCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHHH AASDYVNGQLLVIDGGYSIR HHHHHCCCEEEEEECCCCCC >Mature Secondary Structure SFSIEDFSLDFFSLHNKVAIVTGAAGELGRGLCSALAKAGANLLLVDIKEPDNRYLKHL CCCCCCCCCHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH THEGVEVEFMTIDITKPDASCTIINRCLERFGQLDILVNNAGVCNINRPIDFNRNDWDPM HCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCEEEEEECCCEEECCCCCCCCCCCCCCE INLNLNAAFDMSQAALNIFVPQRKGKIINMCSVLSFHGGRWSPGYAATKHALAGLTKAYA EEEEECCCCCCCCCEEEEEEECCCCCEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH DDFAEYNIQINGIAPGYYVSEMTAIIYNNPKIKELIKGRIPAQRWGRAQDLMGAMVFLAS HHHHHEEEEEEEECCCHHHHHEEEEEECCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHHH AASDYVNGQLLVIDGGYSIR HHHHHCCCEEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9278503; 9205837 [H]