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The map label for this gene is dnaQ [H]

Identifier: 209695823

GI number: 209695823

Start: 2568079

End: 2568810

Strand: Reverse

Name: dnaQ [H]

Synonym: VSAL_I2398

Alternate gene names: 209695823

Gene position: 2568810-2568079 (Counterclockwise)

Preceding gene: 209695825

Following gene: 209695822

Centisome position: 77.25

GC content: 39.62

Gene sequence:

>732_bases
ATGAATACTAGCGACAATTCCCCGAATAGAATTATTGTTCTCGATACAGAAACCACCGGTATGAATTTATCTGGCGGCCC
TATTTATGAGGGTCACCGTATAATTGAAATTGGTGCGGTAGAAATAATCAACCGAAAATTAACTGGAAATCATTTTCATG
TATACATTAAGCCAGATCGACTGATTGATCTTGAAGCTATTGATGTTCATGGTATTACCGATGAATTTTTGTATGGTAAG
CCAGAATATAAAGACATCCATGATGAATTTTTAGCGTTCATTAAAGGGGCTGAGCTTGTCGCTCACAATGCACCCTTTGA
TGTTGGGTTTATGGATTATGAATTCAGTAAACTTAACAAACTTATTGGTACCACGGATCAGTATTGTAAGATCACCGATA
CCTTGGCCATGGCGAAGAAAATTTCCCCTGGTAAGCGAAATAATCTAGATGTGTTATGTGGTCGTTACGGCATAGATAAC
TCGCATCGAACGCTTCACGGCGCTTTACTCGATGCCGAAATACTGGCAGATGTTTATCTGTTAATGACAGGCGGACAAAC
CAGCTTAAGTTTCTCAGCAGGAGGAAATGAGTCTGATTCTTCTGAAGAAAGTATTAATAGATTGAATTTAGGACGAAAAG
GATTAAAGGTTTTACGTGCAACGGCCGATGAATTAGAAGCGCATGAAAAGCGCTTGGATATCGTTGGTGATGCCTGTTTG
TGGCGTAATTAG

Upstream 100 bases:

>100_bases
AGGATTGCCTAAGCAAGAGCCATCTGTGAAAATTTCAACCTGTTTCATTATCTCTGTTATCATTAGAGGAATTTAGAAAT
AGTCTGACACAAATGAGCCT

Downstream 100 bases:

>100_bases
GAGTTTTAGTATGTGGCGGTTATTGATAATTGCACTTTTTGTACCGATAGTGAGTTGGGCAAAGAGCACCGAAATGTCGT
GGTTGGACAACCGCTTTAGA

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MNTSDNSPNRIIVLDTETTGMNLSGGPIYEGHRIIEIGAVEIINRKLTGNHFHVYIKPDRLIDLEAIDVHGITDEFLYGK
PEYKDIHDEFLAFIKGAELVAHNAPFDVGFMDYEFSKLNKLIGTTDQYCKITDTLAMAKKISPGKRNNLDVLCGRYGIDN
SHRTLHGALLDAEILADVYLLMTGGQTSLSFSAGGNESDSSEESINRLNLGRKGLKVLRATADELEAHEKRLDIVGDACL
WRN

Sequences:

>Translated_243_residues
MNTSDNSPNRIIVLDTETTGMNLSGGPIYEGHRIIEIGAVEIINRKLTGNHFHVYIKPDRLIDLEAIDVHGITDEFLYGK
PEYKDIHDEFLAFIKGAELVAHNAPFDVGFMDYEFSKLNKLIGTTDQYCKITDTLAMAKKISPGKRNNLDVLCGRYGIDN
SHRTLHGALLDAEILADVYLLMTGGQTSLSFSAGGNESDSSEESINRLNLGRKGLKVLRATADELEAHEKRLDIVGDACL
WRN
>Mature_243_residues
MNTSDNSPNRIIVLDTETTGMNLSGGPIYEGHRIIEIGAVEIINRKLTGNHFHVYIKPDRLIDLEAIDVHGITDEFLYGK
PEYKDIHDEFLAFIKGAELVAHNAPFDVGFMDYEFSKLNKLIGTTDQYCKITDTLAMAKKISPGKRNNLDVLCGRYGIDN
SHRTLHGALLDAEILADVYLLMTGGQTSLSFSAGGNESDSSEESINRLNLGRKGLKVLRATADELEAHEKRLDIVGDACL
WRN

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=238, Percent_Identity=61.3445378151261, Blast_Score=303, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26966; Mature: 26966

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSDNSPNRIIVLDTETTGMNLSGGPIYEGHRIIEIGAVEIINRKLTGNHFHVYIKPDR
CCCCCCCCCEEEEEECCCCCCCCCCCCEECCCEEEEECCEEEEEHEECCCEEEEEECCCC
LIDLEAIDVHGITDEFLYGKPEYKDIHDEFLAFIKGAELVAHNAPFDVGFMDYEFSKLNK
EEEEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEECCHHHHHHH
LIGTTDQYCKITDTLAMAKKISPGKRNNLDVLCGRYGIDNSHRTLHGALLDAEILADVYL
HHCCCCHHEEHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHEEEE
LMTGGQTSLSFSAGGNESDSSEESINRLNLGRKGLKVLRATADELEAHEKRLDIVGDACL
EEECCCCEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHC
WRN
CCC
>Mature Secondary Structure
MNTSDNSPNRIIVLDTETTGMNLSGGPIYEGHRIIEIGAVEIINRKLTGNHFHVYIKPDR
CCCCCCCCCEEEEEECCCCCCCCCCCCEECCCEEEEECCEEEEEHEECCCEEEEEECCCC
LIDLEAIDVHGITDEFLYGKPEYKDIHDEFLAFIKGAELVAHNAPFDVGFMDYEFSKLNK
EEEEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEECCHHHHHHH
LIGTTDQYCKITDTLAMAKKISPGKRNNLDVLCGRYGIDNSHRTLHGALLDAEILADVYL
HHCCCCHHEEHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHEEEE
LMTGGQTSLSFSAGGNESDSSEESINRLNLGRKGLKVLRATADELEAHEKRLDIVGDACL
EEECCCCEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHC
WRN
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]