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The map label for this gene is tolR [H]

Identifier: 209695363

GI number: 209695363

Start: 2029999

End: 2030445

Strand: Direct

Name: tolR [H]

Synonym: VSAL_I1896

Alternate gene names: 209695363

Gene position: 2029999-2030445 (Clockwise)

Preceding gene: 209695362

Following gene: 209695364

Centisome position: 61.05

GC content: 40.04

Gene sequence:

>447_bases
ATGTCTGGCTATCAACCTAAAAAACGCAAGTTAACCGCTGAGATTAATGTTGTACCTTATATTGACGTTATGTTGGTATT
GCTAATTATCTTTATGGTAACGGCTCCTTTTGTGACTCAAGGGGTAGACGTGAAATTACCAGAGATGACTAATGCGAAAT
CAGCACAAGAAATGGCAGGTGAAGATCCTAATGCAACGTTTATTATTGTCGAGATTGATAAAGACGGAAATCTAGGCTTA
AGTGTTGATAATCAAGACGTACGTCGTCCAATGTCAATGCAAGAAATGATAATGAACGTTAAAGCAGAACTAAGCATTAA
GCCTAATTCTCCCGTCGCAGTTGGCGGGGATGCCAGTACGCCATATTCAGAGATAGTATTAGTTCTTGATGAATTAAGCC
GCGCAGGGGTAAGTAAAGTTGGGTTACTTACCGATCTCAAGGAATAG

Upstream 100 bases:

>100_bases
TAAGTGTGAAAGTAGGTAAGTTAGAGCATAACTACGCTGCATTTATGGATGAGTTTTCTAGTATTCTACATCGTCAAGCA
ATGGCAAGTCAGGAGAAGTA

Downstream 100 bases:

>100_bases
AAGTGAATAATAATCGATGAAATCGGATAATAATTACACCTTTGCTATTGTTGTTTCTGTCGTGTTGCACTTGCTGCTCG
CTGTCGCGTTGATCTTTGGT

Product: TolR protein, membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MSGYQPKKRKLTAEINVVPYIDVMLVLLIIFMVTAPFVTQGVDVKLPEMTNAKSAQEMAGEDPNATFIIVEIDKDGNLGL
SVDNQDVRRPMSMQEMIMNVKAELSIKPNSPVAVGGDASTPYSEIVLVLDELSRAGVSKVGLLTDLKE

Sequences:

>Translated_148_residues
MSGYQPKKRKLTAEINVVPYIDVMLVLLIIFMVTAPFVTQGVDVKLPEMTNAKSAQEMAGEDPNATFIIVEIDKDGNLGL
SVDNQDVRRPMSMQEMIMNVKAELSIKPNSPVAVGGDASTPYSEIVLVLDELSRAGVSKVGLLTDLKE
>Mature_147_residues
SGYQPKKRKLTAEINVVPYIDVMLVLLIIFMVTAPFVTQGVDVKLPEMTNAKSAQEMAGEDPNATFIIVEIDKDGNLGLS
VDNQDVRRPMSMQEMIMNVKAELSIKPNSPVAVGGDASTPYSEIVLVLDELSRAGVSKVGLLTDLKE

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1786959, Length=134, Percent_Identity=36.5671641791045, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1789380, Length=130, Percent_Identity=34.6153846153846, Blast_Score=64, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014168
- InterPro:   IPR003400 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 16095; Mature: 15964

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGYQPKKRKLTAEINVVPYIDVMLVLLIIFMVTAPFVTQGVDVKLPEMTNAKSAQEMAG
CCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHCC
EDPNATFIIVEIDKDGNLGLSVDNQDVRRPMSMQEMIMNVKAELSIKPNSPVAVGGDAST
CCCCCEEEEEEECCCCCEEEEECCHHHHCCCCHHHHHHCCHHEEEECCCCCEEECCCCCC
PYSEIVLVLDELSRAGVSKVGLLTDLKE
CHHHHHHHHHHHHHCCCCHHHHHHCCCC
>Mature Secondary Structure 
SGYQPKKRKLTAEINVVPYIDVMLVLLIIFMVTAPFVTQGVDVKLPEMTNAKSAQEMAG
CCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCHHHHCC
EDPNATFIIVEIDKDGNLGLSVDNQDVRRPMSMQEMIMNVKAELSIKPNSPVAVGGDAST
CCCCCEEEEEEECCCCCEEEEECCHHHHCCCCHHHHHHCCHHEEEECCCCCEEECCCCCC
PYSEIVLVLDELSRAGVSKVGLLTDLKE
CHHHHHHHHHHHHHCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]