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The map label for this gene is moaE [H]

Identifier: 209695347

GI number: 209695347

Start: 2014798

End: 2015244

Strand: Direct

Name: moaE [H]

Synonym: VSAL_I1880

Alternate gene names: 209695347

Gene position: 2014798-2015244 (Clockwise)

Preceding gene: 209695346

Following gene: 209695353

Centisome position: 60.59

GC content: 42.06

Gene sequence:

>447_bases
ATGATTTCTGTTCAAGAACATGACTTCAATGTTGGTGATGAATATAATCTCTTAGCAGAAGGCACGGCCTCTGGTGCTGT
GGTTACTTTTATCGGTAAGGTTCGAGATATGAACCTTGGTGATGATGTGACGGGGCTTTCTTTAGAGCATTACCCCGGTA
TGACAGAAAAATCATTGAATGATATTGTTGCACAGTCGAAAGAGCGCTGGCGGCTCTTAAAAGTGAAAGTGATTCATCGT
GTTGGTGATCTGGAACTGGGCGATCAAATTGTGTTTGTTGGCGTATCGAGTGCACACCGTGGTGCTGCGTTTGAATCTTG
CGAATTCATTATGGATTACTTAAAAACAAATGCACCTTTTTGGAAGAAAGAAAGAACAACCAAAGAAGTACGTTGGGTTG
AATCTAGAGACACAGATAAATCTGCAGCGCAGCGTTGGGAAAAATAG

Upstream 100 bases:

>100_bases
AAATTGCTTGTCGCAATAAATCAAACTATTTCAAGCTTAGATTCCGCGGTTGTTGATGGTGATGAAGTCGCCTTTTTCCC
ACCAGTAACAGGTGGTTAAG

Downstream 100 bases:

>100_bases
ACCGAATTAGCTGATGTTTATATAAATAAAAAGGGAAGAGAGCATAAGCTTTCTTCCCTTTTTTAGTTTTATGTATTCTA
CAGGTCAGCTATTTATTATA

Product: molybdopterin-converting factor subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MISVQEHDFNVGDEYNLLAEGTASGAVVTFIGKVRDMNLGDDVTGLSLEHYPGMTEKSLNDIVAQSKERWRLLKVKVIHR
VGDLELGDQIVFVGVSSAHRGAAFESCEFIMDYLKTNAPFWKKERTTKEVRWVESRDTDKSAAQRWEK

Sequences:

>Translated_148_residues
MISVQEHDFNVGDEYNLLAEGTASGAVVTFIGKVRDMNLGDDVTGLSLEHYPGMTEKSLNDIVAQSKERWRLLKVKVIHR
VGDLELGDQIVFVGVSSAHRGAAFESCEFIMDYLKTNAPFWKKERTTKEVRWVESRDTDKSAAQRWEK
>Mature_148_residues
MISVQEHDFNVGDEYNLLAEGTASGAVVTFIGKVRDMNLGDDVTGLSLEHYPGMTEKSLNDIVAQSKERWRLLKVKVIHR
VGDLELGDQIVFVGVSSAHRGAAFESCEFIMDYLKTNAPFWKKERTTKEVRWVESRDTDKSAAQRWEK

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=120, Percent_Identity=31.6666666666667, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1787003, Length=145, Percent_Identity=61.3793103448276, Blast_Score=189, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17509279, Length=108, Percent_Identity=34.2592592592593, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356259, Length=111, Percent_Identity=39.6396396396396, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16778; Mature: 16778

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVQEHDFNVGDEYNLLAEGTASGAVVTFIGKVRDMNLGDDVTGLSLEHYPGMTEKSLN
CCCCCCCCCCCCCCCCEEECCCCCCEEEEEEHHHHCCCCCCCCCCCCHHHCCCCCHHHHH
DIVAQSKERWRLLKVKVIHRVGDLELGDQIVFVGVSSAHRGAAFESCEFIMDYLKTNAPF
HHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
WKKERTTKEVRWVESRDTDKSAAQRWEK
CCCCCCHHHHHCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MISVQEHDFNVGDEYNLLAEGTASGAVVTFIGKVRDMNLGDDVTGLSLEHYPGMTEKSLN
CCCCCCCCCCCCCCCCEEECCCCCCEEEEEEHHHHCCCCCCCCCCCCHHHCCCCCHHHHH
DIVAQSKERWRLLKVKVIHRVGDLELGDQIVFVGVSSAHRGAAFESCEFIMDYLKTNAPF
HHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
WKKERTTKEVRWVESRDTDKSAAQRWEK
CCCCCCHHHHHCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]