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The map label for this gene is gsk [H]

Identifier: 209695314

GI number: 209695314

Start: 1982083

End: 1983387

Strand: Direct

Name: gsk [H]

Synonym: VSAL_I1847

Alternate gene names: 209695314

Gene position: 1982083-1983387 (Clockwise)

Preceding gene: 209695311

Following gene: 209695317

Centisome position: 59.61

GC content: 40.23

Gene sequence:

>1305_bases
ATGAAGTTTCCAGGTCAACGTAAATCCAAGCATTATTTTCCTGTTCACGCTCGTGATCCATTAGTGAGTCAAGCTCAAGA
AACCAAAAAAATGTCGCGTACGCACATTATTGGTATTGATCAAACCTTAGTGGATATTGAAGCTAGAATTGATGATGCTT
TTATTGAAAAGTATGGCTTGAGTAAAGGACACTCACTGGTTATCGATAATGATAAAGCGGAAATGCTTTATAATGAGCTT
AAAGATAACAATATGATCACCAACGAATACGCTGGTGGCACGATTGGTAATACACTTCATAACTATTCAGTGCTTGCTGA
TGATAAATCAACACTGCTTGGTGTTATGAGTGAAGATATCCATATTGGTAGTTATTCTTATCGTTACCTTTGTAATACTT
CAAGCCGTATGGATTTGAATTATCTGCAGCCTGTACCTGGTGCAATAGGCCGTTGTTTTGCTTTAATTAGCCAAGATGGC
GAGCGTACGTTTGCAATCAGTGAAGGGGACATGAATCAACTTCGTGCTGATAGTATTCCTGAAAAGATTTTTAAAAATGC
GTCTGCATTAGTATTAACGGCTTATCTTGTTCGTTGTAAAGAGGGTGACCCAATGCCTGAAGCAACCATGAAAGCCATTG
AGTTCGCGAAGAAATATGATGTGCCTGTTGTCCTAACTATGGGGACCAAATTTGTTGTTCAAGATGACCCTCAATATTGG
CGTGACTTCCTAAGTGATCATGTGTCTGTTGTGGCAATGAATGAAGAAGAAGGTGAAGCATTAACGGGTGCTTCTGACCC
ATTAGAAGCGGCAGATAAAGCGCTTGAGTGGGTTGATCTTGTTTTATGTACTGCTGGCCCTGTTGGACTGTACATGGCAG
GTTACACAGAAGAATCAGCGAAACGTGAAACATCGTTGCCATTACTTCCAGGAACAATCGCTGAATTTAATCAATATGAA
TTCAGTCGTCCAGCAGTTAAAGCAAGTTGTGATCAGCCGACAAAAGTATATTCTCATATTTCACCGTACATGGGTGGCCC
TGAGAAAATCAAAAATACGAATGGCGCGGGTGATGGTGCTTTGTCTGCATTATTACATGATATGGCTGCAAATCATTACC
ATCGTAATAATGTACCGAACTCAAGTAAGCATCAGCATTCTTACTTAACGTACTCTTCATTATCTCAAGTATGTAAATAC
TCAAACCGAGTAAGCTTTGAGGTTTTGGCTCAGCATTCACCACGCTTATCTCGTGGGTTACCTGAACGCGAAGACAGTTT
AGAAGAGTCATACTGGGAAAGATAA

Upstream 100 bases:

>100_bases
ACGTTTGCCTTTAAAAGGTTACTATATGAGGTATTGCGAGGGCGTTAAGCAAGGGCTAAACTTCCGCACTTATTCCCTTA
GCCAGTTGAATGATTATTTT

Downstream 100 bases:

>100_bases
TAACAGTGTGCTTAGAATGAAAGAAAGCGGAGATAATTAATTTTATCTCCGCTTTTTTATTGGTTCAATTAAGCGCGAAT
AATCGTACTTAGTGTGAATG

Product: inosine-guanosine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKFPGQRKSKHYFPVHARDPLVSQAQETKKMSRTHIIGIDQTLVDIEARIDDAFIEKYGLSKGHSLVIDNDKAEMLYNEL
KDNNMITNEYAGGTIGNTLHNYSVLADDKSTLLGVMSEDIHIGSYSYRYLCNTSSRMDLNYLQPVPGAIGRCFALISQDG
ERTFAISEGDMNQLRADSIPEKIFKNASALVLTAYLVRCKEGDPMPEATMKAIEFAKKYDVPVVLTMGTKFVVQDDPQYW
RDFLSDHVSVVAMNEEEGEALTGASDPLEAADKALEWVDLVLCTAGPVGLYMAGYTEESAKRETSLPLLPGTIAEFNQYE
FSRPAVKASCDQPTKVYSHISPYMGGPEKIKNTNGAGDGALSALLHDMAANHYHRNNVPNSSKHQHSYLTYSSLSQVCKY
SNRVSFEVLAQHSPRLSRGLPEREDSLEESYWER

Sequences:

>Translated_434_residues
MKFPGQRKSKHYFPVHARDPLVSQAQETKKMSRTHIIGIDQTLVDIEARIDDAFIEKYGLSKGHSLVIDNDKAEMLYNEL
KDNNMITNEYAGGTIGNTLHNYSVLADDKSTLLGVMSEDIHIGSYSYRYLCNTSSRMDLNYLQPVPGAIGRCFALISQDG
ERTFAISEGDMNQLRADSIPEKIFKNASALVLTAYLVRCKEGDPMPEATMKAIEFAKKYDVPVVLTMGTKFVVQDDPQYW
RDFLSDHVSVVAMNEEEGEALTGASDPLEAADKALEWVDLVLCTAGPVGLYMAGYTEESAKRETSLPLLPGTIAEFNQYE
FSRPAVKASCDQPTKVYSHISPYMGGPEKIKNTNGAGDGALSALLHDMAANHYHRNNVPNSSKHQHSYLTYSSLSQVCKY
SNRVSFEVLAQHSPRLSRGLPEREDSLEESYWER
>Mature_434_residues
MKFPGQRKSKHYFPVHARDPLVSQAQETKKMSRTHIIGIDQTLVDIEARIDDAFIEKYGLSKGHSLVIDNDKAEMLYNEL
KDNNMITNEYAGGTIGNTLHNYSVLADDKSTLLGVMSEDIHIGSYSYRYLCNTSSRMDLNYLQPVPGAIGRCFALISQDG
ERTFAISEGDMNQLRADSIPEKIFKNASALVLTAYLVRCKEGDPMPEATMKAIEFAKKYDVPVVLTMGTKFVVQDDPQYW
RDFLSDHVSVVAMNEEEGEALTGASDPLEAADKALEWVDLVLCTAGPVGLYMAGYTEESAKRETSLPLLPGTIAEFNQYE
FSRPAVKASCDQPTKVYSHISPYMGGPEKIKNTNGAGDGALSALLHDMAANHYHRNNVPNSSKHQHSYLTYSSLSQVCKY
SNRVSFEVLAQHSPRLSRGLPEREDSLEESYWER

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1786684, Length=434, Percent_Identity=73.963133640553, Blast_Score=698, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.73 [H]

Molecular weight: Translated: 48422; Mature: 48422

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPGQRKSKHYFPVHARDPLVSQAQETKKMSRTHIIGIDQTLVDIEARIDDAFIEKYGL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHCC
SKGHSLVIDNDKAEMLYNELKDNNMITNEYAGGTIGNTLHNYSVLADDKSTLLGVMSEDI
CCCCEEEEECCHHHHHHHHHCCCCEEECCCCCCCCCCHHHCCEEEECCHHHHHHHHHCCE
HIGSYSYRYLCNTSSRMDLNYLQPVPGAIGRCFALISQDGERTFAISEGDMNQLRADSIP
EECCEEEEEEECCCCCCCCHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCHH
EKIFKNASALVLTAYLVRCKEGDPMPEATMKAIEFAKKYDVPVVLTMGTKFVVQDDPQYW
HHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHH
RDFLSDHVSVVAMNEEEGEALTGASDPLEAADKALEWVDLVLCTAGPVGLYMAGYTEESA
HHHHHCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCHHEEEECCCCHHH
KRETSLPLLPGTIAEFNQYEFSRPAVKASCDQPTKVYSHISPYMGGPEKIKNTNGAGDGA
HHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCHHH
LSALLHDMAANHYHRNNVPNSSKHQHSYLTYSSLSQVCKYSNRVSFEVLAQHSPRLSRGL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHEEHHHHHHHHHHCCCCCEEHHCCCCCHHHCCC
PEREDSLEESYWER
CCHHHHHHHHHCCC
>Mature Secondary Structure
MKFPGQRKSKHYFPVHARDPLVSQAQETKKMSRTHIIGIDQTLVDIEARIDDAFIEKYGL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHCC
SKGHSLVIDNDKAEMLYNELKDNNMITNEYAGGTIGNTLHNYSVLADDKSTLLGVMSEDI
CCCCEEEEECCHHHHHHHHHCCCCEEECCCCCCCCCCHHHCCEEEECCHHHHHHHHHCCE
HIGSYSYRYLCNTSSRMDLNYLQPVPGAIGRCFALISQDGERTFAISEGDMNQLRADSIP
EECCEEEEEEECCCCCCCCHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCHH
EKIFKNASALVLTAYLVRCKEGDPMPEATMKAIEFAKKYDVPVVLTMGTKFVVQDDPQYW
HHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHH
RDFLSDHVSVVAMNEEEGEALTGASDPLEAADKALEWVDLVLCTAGPVGLYMAGYTEESA
HHHHHCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCHHEEEECCCCHHH
KRETSLPLLPGTIAEFNQYEFSRPAVKASCDQPTKVYSHISPYMGGPEKIKNTNGAGDGA
HHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCHHH
LSALLHDMAANHYHRNNVPNSSKHQHSYLTYSSLSQVCKYSNRVSFEVLAQHSPRLSRGL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHEEHHHHHHHHHHCCCCCEEHHCCCCCHHHCCC
PEREDSLEESYWER
CCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]