Click here to switch to the map view.

The map label for this gene is ompA [H]

Identifier: 209695291

GI number: 209695291

Start: 1943870

End: 1944973

Strand: Direct

Name: ompA [H]

Synonym: VSAL_I1819

Alternate gene names: 209695291

Gene position: 1943870-1944973 (Clockwise)

Preceding gene: 209695287

Following gene: 209695292

Centisome position: 58.46

GC content: 36.14

Gene sequence:

>1104_bases
ATGCATATAACTTATCTATTACATATAGATGATAACATTAGTCGTAATAATGTAAGTATGTGTGAATTATTGGTTATGAA
GAAGATATCGTATTGTATTTTAAGTTTGGGTATTGCATGTAATGCTAGTGCAAATACCAATACCGAAGATGAAACCATCT
ATATTGGTGGCAAAATCGGTTGGACTCATTTTTCTAATGGTTGTGAATCACAAAATTTAGATTGTGATAAAGAAGCTATG
GGGGGAGGTGTTTTTCTTGGTTATAAACTAAATGAATGGCTTGCAATTGAAGGTGGGTATGATTATTTAGGTAAAGCGAA
AGCGATTTACCCAAGTCTTGATGACCCTTCTATTGATGCTCCTTATAGCGCAAAGTTTCAAGGTATAGAGTTAGGACTTA
AGGCTGACTATTATTTAAATGATAATTGGAATGTTTTTGGCAAAGTTGGTGGCCTTGGATGGAGAGCAGATAAGAAAGGA
GAAGAATTAAACTATGACGTTGAAGGACGGGATCAAGATATTTCGTTAATGCTTGGGGCTGGCCTTGAGTACCGTTTAAC
TAAACAGTTAAAAACTCGATTTGAATATCAATGGTTTGATAGTGTTGGTGGTGAAAATACAGGTGGTTCAAATATTAATT
TTATTACGATTGGCTTGACTTATTCTTTTGGTTCAAAAGAGGAAGTAGTCGTTATTGCCGAGCCTGATCCACCAGTACGT
ATTGTTAAAGCAGAAAAACTTACCCTTAATGAGCTGAATGGACAAGCTTTGTTTGGCTTTGATAGTGCTAAATTATCTTC
AGAAGTAGAAGCCCATTTTGATTCAATTTTAGAAAGACTTAAAAACAACCCAACATCGGAATTAAGTATTGTCGGTCATA
CGGACTCTCAAGGTTCAGATAAATACAATGAAGGGTTATCTTTGAGACGAGCACAGAGTGTTGCTAATTACTTTGAAAGC
AATGGTATTGCAATGAGTCGAATCAAAGTTGAAGGTCGAGGTGAGACCGATCCTGTTGCCGATAATAACACGCTAAAAGG
GCGATCAATGAACCGTCGTGTTGATTTAATTTCTCCTGCTTTTACTTCAGAGGTTAAACCATGA

Upstream 100 bases:

>100_bases
TTTCATCATTAACAGTTACGTTTTATCTGATTAAATACAATGGCGCTAATTAATTTACAAAAGTATCACAAGTGACACAG
TAATCTTTTGTTTAAGTACG

Downstream 100 bases:

>100_bases
AACTAAGAACAATTTTTATTATTGTATTATCAAATTTGCTTTTTGCTTGTGGTGGAGAGAACAGCGGAGCACCATCCCAA
GGTAAACGCACTGAAAATTG

Product: outer membrane protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MHITYLLHIDDNISRNNVSMCELLVMKKISYCILSLGIACNASANTNTEDETIYIGGKIGWTHFSNGCESQNLDCDKEAM
GGGVFLGYKLNEWLAIEGGYDYLGKAKAIYPSLDDPSIDAPYSAKFQGIELGLKADYYLNDNWNVFGKVGGLGWRADKKG
EELNYDVEGRDQDISLMLGAGLEYRLTKQLKTRFEYQWFDSVGGENTGGSNINFITIGLTYSFGSKEEVVVIAEPDPPVR
IVKAEKLTLNELNGQALFGFDSAKLSSEVEAHFDSILERLKNNPTSELSIVGHTDSQGSDKYNEGLSLRRAQSVANYFES
NGIAMSRIKVEGRGETDPVADNNTLKGRSMNRRVDLISPAFTSEVKP

Sequences:

>Translated_367_residues
MHITYLLHIDDNISRNNVSMCELLVMKKISYCILSLGIACNASANTNTEDETIYIGGKIGWTHFSNGCESQNLDCDKEAM
GGGVFLGYKLNEWLAIEGGYDYLGKAKAIYPSLDDPSIDAPYSAKFQGIELGLKADYYLNDNWNVFGKVGGLGWRADKKG
EELNYDVEGRDQDISLMLGAGLEYRLTKQLKTRFEYQWFDSVGGENTGGSNINFITIGLTYSFGSKEEVVVIAEPDPPVR
IVKAEKLTLNELNGQALFGFDSAKLSSEVEAHFDSILERLKNNPTSELSIVGHTDSQGSDKYNEGLSLRRAQSVANYFES
NGIAMSRIKVEGRGETDPVADNNTLKGRSMNRRVDLISPAFTSEVKP
>Mature_367_residues
MHITYLLHIDDNISRNNVSMCELLVMKKISYCILSLGIACNASANTNTEDETIYIGGKIGWTHFSNGCESQNLDCDKEAM
GGGVFLGYKLNEWLAIEGGYDYLGKAKAIYPSLDDPSIDAPYSAKFQGIELGLKADYYLNDNWNVFGKVGGLGWRADKKG
EELNYDVEGRDQDISLMLGAGLEYRLTKQLKTRFEYQWFDSVGGENTGGSNINFITIGLTYSFGSKEEVVVIAEPDPPVR
IVKAEKLTLNELNGQALFGFDSAKLSSEVEAHFDSILERLKNNPTSELSIVGHTDSQGSDKYNEGLSLRRAQSVANYFES
NGIAMSRIKVEGRGETDPVADNNTLKGRSMNRRVDLISPAFTSEVKP

Specific function: Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes [H

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787191, Length=355, Percent_Identity=31.830985915493, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1788957, Length=102, Percent_Identity=37.2549019607843, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994946, Length=103, Percent_Identity=35.9223300970874, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1480 Molecules/Cell In: Growth Phase, Mi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR002368
- InterPro:   IPR006690
- InterPro:   IPR000498
- InterPro:   IPR006665 [H]

Pfam domain/function: PF00691 OmpA; PF01389 OmpA_membrane [H]

EC number: NA

Molecular weight: Translated: 40533; Mature: 40533

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHITYLLHIDDNISRNNVSMCELLVMKKISYCILSLGIACNASANTNTEDETIYIGGKIG
CEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCEEEECCEEE
WTHFSNGCESQNLDCDKEAMGGGVFLGYKLNEWLAIEGGYDYLGKAKAIYPSLDDPSIDA
ECCCCCCCCCCCCCCCHHHCCCEEEEEEEECCEEEEECCCCCCCCCEEECCCCCCCCCCC
PYSAKFQGIELGLKADYYLNDNWNVFGKVGGLGWRADKKGEELNYDVEGRDQDISLMLGA
CCCCEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECC
GLEYRLTKQLKTRFEYQWFDSVGGENTGGSNINFITIGLTYSFGSKEEVVVIAEPDPPVR
CCCEEHHHHHHHHCCEEEHHCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEECCCCCEE
IVKAEKLTLNELNGQALFGFDSAKLSSEVEAHFDSILERLKNNPTSELSIVGHTDSQGSD
EEEECEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
KYNEGLSLRRAQSVANYFESNGIAMSRIKVEGRGETDPVADNNTLKGRSMNRRVDLISPA
HHHCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCH
FTSEVKP
HHCCCCC
>Mature Secondary Structure
MHITYLLHIDDNISRNNVSMCELLVMKKISYCILSLGIACNASANTNTEDETIYIGGKIG
CEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCEEEECCEEE
WTHFSNGCESQNLDCDKEAMGGGVFLGYKLNEWLAIEGGYDYLGKAKAIYPSLDDPSIDA
ECCCCCCCCCCCCCCCHHHCCCEEEEEEEECCEEEEECCCCCCCCCEEECCCCCCCCCCC
PYSAKFQGIELGLKADYYLNDNWNVFGKVGGLGWRADKKGEELNYDVEGRDQDISLMLGA
CCCCEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECC
GLEYRLTKQLKTRFEYQWFDSVGGENTGGSNINFITIGLTYSFGSKEEVVVIAEPDPPVR
CCCEEHHHHHHHHCCEEEHHCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEECCCCCEE
IVKAEKLTLNELNGQALFGFDSAKLSSEVEAHFDSILERLKNNPTSELSIVGHTDSQGSD
EEEECEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
KYNEGLSLRRAQSVANYFESNGIAMSRIKVEGRGETDPVADNNTLKGRSMNRRVDLISPA
HHHCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCH
FTSEVKP
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]