Click here to switch to the map view.

The map label for this gene is aroH [H]

Identifier: 209695212

GI number: 209695212

Start: 1838388

End: 1839440

Strand: Direct

Name: aroH [H]

Synonym: VSAL_I1727

Alternate gene names: 209695212

Gene position: 1838388-1839440 (Clockwise)

Preceding gene: 209695210

Following gene: 209695213

Centisome position: 55.29

GC content: 41.22

Gene sequence:

>1053_bases
ATGCCATTGCAAACAGATGAACTTCGTACTCAGCCTTTAGGCCCAATGCCTACTCCCGCTGAATTAACTGCTGCCTATCC
TCTTACTGACGATGTTGCCGAACACATTGAGCAATCTAGAGCTCAAGTTGAAGCAATTTTAACGGGTGAAGACAAACGAC
TTTTAGTCATTGTTGGCCCGTGCTCAGTACATGATACTAAAGCCGCAATGGACTACGCTGAACGTTTAGCTAAGATCCAA
GAATCGTATAAAAATGAGCTTTTCATTGTTATGCGTACGTACTTTGAAAAACCACGTACGATTGTAGGTTGGAAAGGTCT
TATTACCGATCCAAACCTTGATGGTAGTTATGCTCTTGAGGCCGGTCTTCATAAAGCACGTAAACTATTACTGAACATAA
ATAAACTGGGTTTAGCTACAGCGACTGAGTTTTTAGATATGATCACTGGCCAATATATTTCTGACTTGATCACGTGGGGT
GCCATTGGCGCTCGTACTACTGAGTCTCAAATACACCGTGAAATGGCATCAGCCCTTTCTTGTCCTGTTGGATTTAAAAA
CGGTACCAATGGTAATACTCAGATTGCGATGGATGCTATCCGCGCTTCTAAGGCTTCTCATTACTTCTACTCTCCAGATA
AACAAGGCCGCATGACGGTATACCGCACTGCTGGTAACCCTTTTGGTCATGTTATCTTACGTGGTGGTAGCGACAAACCA
AACTATGATATTGATTCTGTAACAGATGCCTGCAAACGGTTAGAAGAAGTAAATTTACCTCCTCATCTGATCGTTGATTT
TAGCCACGCTAACTGTGAGAAACAACACCGTCGTCAACTTGATGTTGCAAAAGATATTTGTAATCAAATTGAATCTGGCA
GCAATCAAGTTGTTGGTATTATGGCTGAAAGCTTTTTAATTGAAGGCAATCAACCAATGACGGATTTAAATAACCTAACT
TATGGCCAATCGATCACTGATCCATGCCTAAGTTGGGAAGATACTGTGACTATGTTAGACATGCTATCAAACTCTATTAA
AACCTCTCGTTAA

Upstream 100 bases:

>100_bases
TTTTCCTTATCTATACACATATCAATCAATTTTTGGGTTTCATCCCTCTTGATTTTCCGTTATCTTACTCTAGTGTATTA
AAAGAATTACAGGCGAAACT

Downstream 100 bases:

>100_bases
TTTAAAGGATAAACTATGCCTGCTTTTGATATCGTTTCTGAAGTTGATAATGTTGAACTAAAAAATGCAGTAGATAACGC
TACTCGTGAATTAGCTACTC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MPLQTDELRTQPLGPMPTPAELTAAYPLTDDVAEHIEQSRAQVEAILTGEDKRLLVIVGPCSVHDTKAAMDYAERLAKIQ
ESYKNELFIVMRTYFEKPRTIVGWKGLITDPNLDGSYALEAGLHKARKLLLNINKLGLATATEFLDMITGQYISDLITWG
AIGARTTESQIHREMASALSCPVGFKNGTNGNTQIAMDAIRASKASHYFYSPDKQGRMTVYRTAGNPFGHVILRGGSDKP
NYDIDSVTDACKRLEEVNLPPHLIVDFSHANCEKQHRRQLDVAKDICNQIESGSNQVVGIMAESFLIEGNQPMTDLNNLT
YGQSITDPCLSWEDTVTMLDMLSNSIKTSR

Sequences:

>Translated_350_residues
MPLQTDELRTQPLGPMPTPAELTAAYPLTDDVAEHIEQSRAQVEAILTGEDKRLLVIVGPCSVHDTKAAMDYAERLAKIQ
ESYKNELFIVMRTYFEKPRTIVGWKGLITDPNLDGSYALEAGLHKARKLLLNINKLGLATATEFLDMITGQYISDLITWG
AIGARTTESQIHREMASALSCPVGFKNGTNGNTQIAMDAIRASKASHYFYSPDKQGRMTVYRTAGNPFGHVILRGGSDKP
NYDIDSVTDACKRLEEVNLPPHLIVDFSHANCEKQHRRQLDVAKDICNQIESGSNQVVGIMAESFLIEGNQPMTDLNNLT
YGQSITDPCLSWEDTVTMLDMLSNSIKTSR
>Mature_349_residues
PLQTDELRTQPLGPMPTPAELTAAYPLTDDVAEHIEQSRAQVEAILTGEDKRLLVIVGPCSVHDTKAAMDYAERLAKIQE
SYKNELFIVMRTYFEKPRTIVGWKGLITDPNLDGSYALEAGLHKARKLLLNINKLGLATATEFLDMITGQYISDLITWGA
IGARTTESQIHREMASALSCPVGFKNGTNGNTQIAMDAIRASKASHYFYSPDKQGRMTVYRTAGNPFGHVILRGGSDKPN
YDIDSVTDACKRLEEVNLPPHLIVDFSHANCEKQHRRQLDVAKDICNQIESGSNQVVGIMAESFLIEGNQPMTDLNNLTY
GQSITDPCLSWEDTVTMLDMLSNSIKTSR

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787996, Length=345, Percent_Identity=64.927536231884, Blast_Score=489, Evalue=1e-139,
Organism=Escherichia coli, GI1786969, Length=350, Percent_Identity=51.1428571428571, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1788953, Length=323, Percent_Identity=49.5356037151703, Blast_Score=326, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6319726, Length=350, Percent_Identity=44.8571428571429, Blast_Score=311, Evalue=1e-85,
Organism=Saccharomyces cerevisiae, GI6320240, Length=352, Percent_Identity=43.1818181818182, Blast_Score=300, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38766; Mature: 38634

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLQTDELRTQPLGPMPTPAELTAAYPLTDDVAEHIEQSRAQVEAILTGEDKRLLVIVGP
CCCCCCCCCCCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHEEHEEECCCCEEEEEECC
CSVHDTKAAMDYAERLAKIQESYKNELFIVMRTYFEKPRTIVGWKGLITDPNLDGSYALE
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCEEEECCCEEECCCCCCCHHHH
AGLHKARKLLLNINKLGLATATEFLDMITGQYISDLITWGAIGARTTESQIHREMASALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
CPVGFKNGTNGNTQIAMDAIRASKASHYFYSPDKQGRMTVYRTAGNPFGHVILRGGSDKP
CCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCCCCEEEEEECCCCCEEEEEECCCCCC
NYDIDSVTDACKRLEEVNLPPHLIVDFSHANCEKQHRRQLDVAKDICNQIESGSNQVVGI
CCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
MAESFLIEGNQPMTDLNNLTYGQSITDPCLSWEDTVTMLDMLSNSIKTSR
EEHEEEECCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PLQTDELRTQPLGPMPTPAELTAAYPLTDDVAEHIEQSRAQVEAILTGEDKRLLVIVGP
CCCCCCCCCCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHEEHEEECCCCEEEEEECC
CSVHDTKAAMDYAERLAKIQESYKNELFIVMRTYFEKPRTIVGWKGLITDPNLDGSYALE
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCEEEECCCEEECCCCCCCHHHH
AGLHKARKLLLNINKLGLATATEFLDMITGQYISDLITWGAIGARTTESQIHREMASALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
CPVGFKNGTNGNTQIAMDAIRASKASHYFYSPDKQGRMTVYRTAGNPFGHVILRGGSDKP
CCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCCCCEEEEEECCCCCEEEEEECCCCCC
NYDIDSVTDACKRLEEVNLPPHLIVDFSHANCEKQHRRQLDVAKDICNQIESGSNQVVGI
CCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
MAESFLIEGNQPMTDLNNLTYGQSITDPCLSWEDTVTMLDMLSNSIKTSR
EEHEEEECCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]