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The map label for this gene is ribE [H]

Identifier: 209694909

GI number: 209694909

Start: 1500753

End: 1501364

Strand: Direct

Name: ribE [H]

Synonym: VSAL_I1383

Alternate gene names: 209694909

Gene position: 1500753-1501364 (Clockwise)

Preceding gene: 209694907

Following gene: 209694912

Centisome position: 45.13

GC content: 37.91

Gene sequence:

>612_bases
ATGTTTACTGGGATTGTAGCAACGACGGCAAAGGTTATTGATATCATTAAAAAAGAGAACTTTCAGACTCATATTGTTGA
AATTCTTGAACCTTACAATCATGAATTAGAAATAGGGGCTTCTGTTGCTCATAACGGGTGCTGTTTGACGGTGACTAAAA
TTGATGGCAACAAAGTCTGGTTTGATTTGATTGAAGAAACGTTACGTTTAACCAACCTTGGTTTCTTAAGTATTGGGCAA
CGAGTCAATATTGAGCGTGCCGCTCGGTTTGGTGATGAGATTGGTGGTCATTCAATGTCAGGTCATATTGTTGATATTAT
GATCGTAAGGGAAGTGATTAAAACCCCCGCGAACTGTAAAATTTGGTTTGATGTTCCACCTACATGGCTCAAATATGTGT
TACATAAAGGGTATGTTGGTGTCGATGGAATTAGTCTTACGATTGGTGACGTTGATGCAAAGGGATTTAACGTGAATCTT
ATCCCTGAAACTCTAGAGAGAACGAATTTAAGTGAGCGTATTGTGGGTGATAAAATTAATTTAGAAATTGATCCGCAAAC
CCAAGCTATTGTCGATACGATTGAGCGAGTATTAGCGAACCAAAATAATTAA

Upstream 100 bases:

>100_bases
TTCACAAAATGAAATATTCAACGTATTGTGATATTTTTAAAAATAGAGAGAGTTAAATAATGCTCTTGAATTTTTAGTAT
CAAATTGATTGGAGAGACGG

Downstream 100 bases:

>100_bases
TTTGATCATAATGAATTAAAACAGCCCGTCTTCATTACTGTCTATCGATAAGTTTATCGTACTGTTATGCGGGTTAACGG
TCATTTTCATTTCAATAGCA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MFTGIVATTAKVIDIIKKENFQTHIVEILEPYNHELEIGASVAHNGCCLTVTKIDGNKVWFDLIEETLRLTNLGFLSIGQ
RVNIERAARFGDEIGGHSMSGHIVDIMIVREVIKTPANCKIWFDVPPTWLKYVLHKGYVGVDGISLTIGDVDAKGFNVNL
IPETLERTNLSERIVGDKINLEIDPQTQAIVDTIERVLANQNN

Sequences:

>Translated_203_residues
MFTGIVATTAKVIDIIKKENFQTHIVEILEPYNHELEIGASVAHNGCCLTVTKIDGNKVWFDLIEETLRLTNLGFLSIGQ
RVNIERAARFGDEIGGHSMSGHIVDIMIVREVIKTPANCKIWFDVPPTWLKYVLHKGYVGVDGISLTIGDVDAKGFNVNL
IPETLERTNLSERIVGDKINLEIDPQTQAIVDTIERVLANQNN
>Mature_203_residues
MFTGIVATTAKVIDIIKKENFQTHIVEILEPYNHELEIGASVAHNGCCLTVTKIDGNKVWFDLIEETLRLTNLGFLSIGQ
RVNIERAARFGDEIGGHSMSGHIVDIMIVREVIKTPANCKIWFDVPPTWLKYVLHKGYVGVDGISLTIGDVDAKGFNVNL
IPETLERTNLSERIVGDKINLEIDPQTQAIVDTIERVLANQNN

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=204, Percent_Identity=58.8235294117647, Blast_Score=243, Evalue=5e-66,
Organism=Saccharomyces cerevisiae, GI6319733, Length=174, Percent_Identity=30.4597701149425, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22606; Mature: 22606

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVATTAKVIDIIKKENFQTHIVEILEPYNHELEIGASVAHNGCCLTVTKIDGNKVW
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCEECCCCEEEEEEEECCCCHH
FDLIEETLRLTNLGFLSIGQRVNIERAARFGDEIGGHSMSGHIVDIMIVREVIKTPANCK
HHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCE
IWFDVPPTWLKYVLHKGYVGVDGISLTIGDVDAKGFNVNLIPETLERTNLSERIVGDKIN
EEEECCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEECHHHHHHCCCHHHHCCCEEE
LEIDPQTQAIVDTIERVLANQNN
EEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFTGIVATTAKVIDIIKKENFQTHIVEILEPYNHELEIGASVAHNGCCLTVTKIDGNKVW
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCEECCCCEEEEEEEECCCCHH
FDLIEETLRLTNLGFLSIGQRVNIERAARFGDEIGGHSMSGHIVDIMIVREVIKTPANCK
HHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCE
IWFDVPPTWLKYVLHKGYVGVDGISLTIGDVDAKGFNVNLIPETLERTNLSERIVGDKIN
EEEECCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEECHHHHHHCCCHHHHCCCEEE
LEIDPQTQAIVDTIERVLANQNN
EEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9022701; 9023191; 9097039; 9278503; 11377200 [H]