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The map label for this gene is nagC [H]

Identifier: 209694408

GI number: 209694408

Start: 923355

End: 924569

Strand: Reverse

Name: nagC [H]

Synonym: VSAL_I0829

Alternate gene names: 209694408

Gene position: 924569-923355 (Counterclockwise)

Preceding gene: 209694409

Following gene: 209694407

Centisome position: 27.81

GC content: 38.77

Gene sequence:

>1215_bases
ATGACTGACGGACAAATTGGTAATGTAGATCTAGTAAAACAATTAAACAGTGCCGCTGTTTATCGTTTAATCGACCAAAA
AGGACCGATTTCTCGAATTCAAATCGCAGACGTTAGTCAACTTGCACCAGCAAGTGTTACCAAGATAACCCGTCAATTAT
TAGAGCGTGGCTTAATTAAAGAAGTCGCGCAACAAGCATCAACAGGTGGTCGAAGAGCAATTTCTTTGACTACCGAAACC
TCACCCTTTCATTCAATCGCAGTGCGCTTAGGTCGTGATTATATTCAACTGAGTCTGTTTGATCTTTCAACAAAAGAATT
AGCCAGTGAATACCAAGAATTTCATTATAGTAACCAAGAACACCTTTTAGATGGCCTAAATAAATTACTTCAAAACTTCA
TTACCCGTAATCAAGACACCATCAAACAACTCATCGCTATTGGTATCACACTCCCTGGTTTGGTTAACCCAGAAACGGGC
GTTGTAGAATATATGCCAAATACCGATATAGACAAACTAGCATTGGCTGACTTCATTAAAGAAACTTTTGATATTCAATG
CTTTGTTGGTAATGATATTCGAGGTTTAGCGCTCGCTGAACACTATTTCGGAGCCTCTCAAGATTGCCGAGATTCTATTC
TAGTGAGTGTTCATAGAGGAACCGGTGCTGGTATTATTGTTAATGGTAAAGTATTTCTAGGGCACAATCGAAACGTTGGA
GAAATCGGTCATATTCAAATCGATCCAATCGGTGATAAATGCCAATGTGGTAACTTTGGTTGCTTAGAAACAGTTGCCGC
AAACCCTGCAATTATTTCACGTATAGAAACGTTACTTGAACAGGGTTATCCATCTAGTCTCTCTCAATTAGAAACGATAA
CAATGTCTGATATCTGCCATGCCGCAAACCATGGAGATGAATTAGCAATACAGACTTTATTACGCGTTGGTAATCAACTT
GGTAAAGCGATTGCAATGACTGTAAACCTATTTAATCCACAAAAAATAGTCATCGCAGGAGCAATCACCCAAGCGGATAA
AATAGTCTTTGCTGCAATACAGAATTGCATTAAAAATCAATCATTAACCGCTTTCCATAAAAACTTACCCGTTGTAGCCT
CACAACTCGACAACCAACCAACTATTGGCGCCTTCTCAATGGTTAAGCGCGCAATGCTTAATGGTGTCTTGTTACAAAAA
TTATTAGATGAATAA

Upstream 100 bases:

>100_bases
GGTCGAATCAAAAAAGACATGGTAGCTAACCTTGCTATTTTTGATCGTGACTTTAATGTAAAAGCGACTGTTGTTAACGG
ACAATACGAGCAAAGTTAAT

Downstream 100 bases:

>100_bases
GAACGAATAATTTTTGTCATGTTACTCTAAGGGCTGCATTTGCGGCCCTTTTTATTACTTTCAGGAAAATATATTTTTAT
GGAGTTGCTCTTTATTATCG

Product: N-acetylglucosamine repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTDGQIGNVDLVKQLNSAAVYRLIDQKGPISRIQIADVSQLAPASVTKITRQLLERGLIKEVAQQASTGGRRAISLTTET
SPFHSIAVRLGRDYIQLSLFDLSTKELASEYQEFHYSNQEHLLDGLNKLLQNFITRNQDTIKQLIAIGITLPGLVNPETG
VVEYMPNTDIDKLALADFIKETFDIQCFVGNDIRGLALAEHYFGASQDCRDSILVSVHRGTGAGIIVNGKVFLGHNRNVG
EIGHIQIDPIGDKCQCGNFGCLETVAANPAIISRIETLLEQGYPSSLSQLETITMSDICHAANHGDELAIQTLLRVGNQL
GKAIAMTVNLFNPQKIVIAGAITQADKIVFAAIQNCIKNQSLTAFHKNLPVVASQLDNQPTIGAFSMVKRAMLNGVLLQK
LLDE

Sequences:

>Translated_404_residues
MTDGQIGNVDLVKQLNSAAVYRLIDQKGPISRIQIADVSQLAPASVTKITRQLLERGLIKEVAQQASTGGRRAISLTTET
SPFHSIAVRLGRDYIQLSLFDLSTKELASEYQEFHYSNQEHLLDGLNKLLQNFITRNQDTIKQLIAIGITLPGLVNPETG
VVEYMPNTDIDKLALADFIKETFDIQCFVGNDIRGLALAEHYFGASQDCRDSILVSVHRGTGAGIIVNGKVFLGHNRNVG
EIGHIQIDPIGDKCQCGNFGCLETVAANPAIISRIETLLEQGYPSSLSQLETITMSDICHAANHGDELAIQTLLRVGNQL
GKAIAMTVNLFNPQKIVIAGAITQADKIVFAAIQNCIKNQSLTAFHKNLPVVASQLDNQPTIGAFSMVKRAMLNGVLLQK
LLDE
>Mature_403_residues
TDGQIGNVDLVKQLNSAAVYRLIDQKGPISRIQIADVSQLAPASVTKITRQLLERGLIKEVAQQASTGGRRAISLTTETS
PFHSIAVRLGRDYIQLSLFDLSTKELASEYQEFHYSNQEHLLDGLNKLLQNFITRNQDTIKQLIAIGITLPGLVNPETGV
VEYMPNTDIDKLALADFIKETFDIQCFVGNDIRGLALAEHYFGASQDCRDSILVSVHRGTGAGIIVNGKVFLGHNRNVGE
IGHIQIDPIGDKCQCGNFGCLETVAANPAIISRIETLLEQGYPSSLSQLETITMSDICHAANHGDELAIQTLLRVGNQLG
KAIAMTVNLFNPQKIVIAGAITQADKIVFAAIQNCIKNQSLTAFHKNLPVVASQLDNQPTIGAFSMVKRAMLNGVLLQKL
LDE

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=289, Percent_Identity=23.5294117647059, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI298566325, Length=289, Percent_Identity=23.5294117647059, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4885285, Length=289, Percent_Identity=23.5294117647059, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI190014632, Length=289, Percent_Identity=23.5294117647059, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786891, Length=406, Percent_Identity=62.5615763546798, Blast_Score=513, Evalue=1e-147,
Organism=Escherichia coli, GI1787878, Length=404, Percent_Identity=39.1089108910891, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI87082127, Length=332, Percent_Identity=23.1927710843373, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87081733, Length=214, Percent_Identity=26.1682242990654, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790522, Length=261, Percent_Identity=23.7547892720307, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 43981; Mature: 43850

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDGQIGNVDLVKQLNSAAVYRLIDQKGPISRIQIADVSQLAPASVTKITRQLLERGLIK
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHH
EVAQQASTGGRRAISLTTETSPFHSIAVRLGRDYIQLSLFDLSTKELASEYQEFHYSNQE
HHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCHH
HLLDGLNKLLQNFITRNQDTIKQLIAIGITLPGLVNPETGVVEYMPNTDIDKLALADFIK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
ETFDIQCFVGNDIRGLALAEHYFGASQDCRDSILVSVHRGTGAGIIVNGKVFLGHNRNVG
HHHEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECEEEECCCCCCC
EIGHIQIDPIGDKCQCGNFGCLETVAANPAIISRIETLLEQGYPSSLSQLETITMSDICH
CCCCEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AANHGDELAIQTLLRVGNQLGKAIAMTVNLFNPQKIVIAGAITQADKIVFAAIQNCIKNQ
HCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHCCC
SLTAFHKNLPVVASQLDNQPTIGAFSMVKRAMLNGVLLQKLLDE
CHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDGQIGNVDLVKQLNSAAVYRLIDQKGPISRIQIADVSQLAPASVTKITRQLLERGLIK
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHH
EVAQQASTGGRRAISLTTETSPFHSIAVRLGRDYIQLSLFDLSTKELASEYQEFHYSNQE
HHHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCHH
HLLDGLNKLLQNFITRNQDTIKQLIAIGITLPGLVNPETGVVEYMPNTDIDKLALADFIK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHH
ETFDIQCFVGNDIRGLALAEHYFGASQDCRDSILVSVHRGTGAGIIVNGKVFLGHNRNVG
HHHEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECEEEECCCCCCC
EIGHIQIDPIGDKCQCGNFGCLETVAANPAIISRIETLLEQGYPSSLSQLETITMSDICH
CCCCEEECCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AANHGDELAIQTLLRVGNQLGKAIAMTVNLFNPQKIVIAGAITQADKIVFAAIQNCIKNQ
HCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHCCC
SLTAFHKNLPVVASQLDNQPTIGAFSMVKRAMLNGVLLQKLLDE
CHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]