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The map label for this gene is engD [H]

Identifier: 209694366

GI number: 209694366

Start: 870657

End: 871748

Strand: Reverse

Name: engD [H]

Synonym: VSAL_I0784

Alternate gene names: 209694366

Gene position: 871748-870657 (Counterclockwise)

Preceding gene: 209694367

Following gene: 209694362

Centisome position: 26.22

GC content: 40.38

Gene sequence:

>1092_bases
ATGGGTTTTAAATGCGGAATCGTTGGTCTTCCAAACGTTGGTAAATCAACACTGTTTAACGCACTAACTAAAGCTGGAAT
CGAAGCAGCAAACTTCCCTTTCTGTACTATTGAACCAAACACCGGTGTGGTTCCTGTTCCTGATCTACGTTTAGATGTAT
TAGCTAAAATCGTAAATCCAGAACGTGTTCTTCCTACTACAATGGAATTTGTAGATATTGCTGGTTTAGTTGCGGGCGCA
TCTAAAGGTGAAGGTCTAGGTAATAAATTCCTTGCTAACATCCGAGAAACTGATGCGATTGGTCATGTTGTTCGCTGTTT
TGAAGATGACAATATCATTCACGTTGCTGGTAAAATATCACCAATTGAAGACATTGAAATTATCAATCTTGAGCTTGCTC
TTGCCGATTTAGATTCATGTGAACGTGCGATCCTGCGTCAAGCGAAAAAAGCAAAAGGCGGCGATCAAACGGCTAAGTTT
GAAATTTCAGTACTTGAAAAGCTATTACCTGTTTTTACAGAAGGTGGCATGGCTCGTACTGTTGAACTTTCAAAAGAAGA
AGTTGCAGCGGTTTCTTACCTTAACTTCCTAACGTTAAAACCAACAATGTATATTGCTAACGTTGCTGAAGATGGTTTTG
AAAATAATCCATTCTTAGATCTTGTTCGTGATTATGCAACAGCAGAAAACAACGTAGTTGTTGCAGTATGTGCTGCGATT
GAATCAGAACTGTCTGAACTTGATGATGAAGATCGTGAAGAATTCTTTGCTGATATGGGCATTGAAGAGCCTGGTCTAAA
CCGTGTAATTCGTTCTGGTTATGATCTACTTGCTCTGCAGACATATTTTACGGCTGGCGTTAAAGAAGTTCGCGCTTGGA
CTATTCCTGTTGGAGCTACGGCACCACAAGCGGCAGGTAAGATCCACACTGACTTTGAAAAAGGCTTTATTCGTGCAGAA
GTTGTAGGTTACGACAACTTTATTGAATTTAGCGGTGAGAGTGGCGCTAAAGAAGCCGGTAAATGGCGTCTAGAAGGTAA
AGATTACATCGTTAAAGATGGTGATGTTGTACATTTCCGCTTCAACGTATAA

Upstream 100 bases:

>100_bases
TCTACTCGTTGCTTAGATATCTTACTTAAAGACGGACTAAGTAAAGCACAAAATCGTTTACACACATTCAAAGCTGAATA
ACAAAGATAAGGTTTACATC

Downstream 100 bases:

>100_bases
TAAAAAAGGCCAGCATATTTGCTGGCCTTTTTATTAGTCACCTAGATTTCAACCACTTAAATGATTTTAATCCTTAGTAA
TGCATCAACACTCACTTCTT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPVPDLRLDVLAKIVNPERVLPTTMEFVDIAGLVAGA
SKGEGLGNKFLANIRETDAIGHVVRCFEDDNIIHVAGKISPIEDIEIINLELALADLDSCERAILRQAKKAKGGDQTAKF
EISVLEKLLPVFTEGGMARTVELSKEEVAAVSYLNFLTLKPTMYIANVAEDGFENNPFLDLVRDYATAENNVVVAVCAAI
ESELSELDDEDREEFFADMGIEEPGLNRVIRSGYDLLALQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAE
VVGYDNFIEFSGESGAKEAGKWRLEGKDYIVKDGDVVHFRFNV

Sequences:

>Translated_363_residues
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPVPDLRLDVLAKIVNPERVLPTTMEFVDIAGLVAGA
SKGEGLGNKFLANIRETDAIGHVVRCFEDDNIIHVAGKISPIEDIEIINLELALADLDSCERAILRQAKKAKGGDQTAKF
EISVLEKLLPVFTEGGMARTVELSKEEVAAVSYLNFLTLKPTMYIANVAEDGFENNPFLDLVRDYATAENNVVVAVCAAI
ESELSELDDEDREEFFADMGIEEPGLNRVIRSGYDLLALQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAE
VVGYDNFIEFSGESGAKEAGKWRLEGKDYIVKDGDVVHFRFNV
>Mature_362_residues
GFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPVPDLRLDVLAKIVNPERVLPTTMEFVDIAGLVAGAS
KGEGLGNKFLANIRETDAIGHVVRCFEDDNIIHVAGKISPIEDIEIINLELALADLDSCERAILRQAKKAKGGDQTAKFE
ISVLEKLLPVFTEGGMARTVELSKEEVAAVSYLNFLTLKPTMYIANVAEDGFENNPFLDLVRDYATAENNVVVAVCAAIE
SELSELDDEDREEFFADMGIEEPGLNRVIRSGYDLLALQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAEV
VGYDNFIEFSGESGAKEAGKWRLEGKDYIVKDGDVVHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=44.2934782608696, Blast_Score=300, Evalue=1e-81,
Organism=Homo sapiens, GI58761502, Length=233, Percent_Identity=36.9098712446352, Blast_Score=152, Evalue=5e-37,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=76.8595041322314, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI1789574, Length=127, Percent_Identity=32.2834645669291, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=365, Percent_Identity=40.5479452054795, Blast_Score=286, Evalue=9e-78,
Organism=Saccharomyces cerevisiae, GI6319499, Length=369, Percent_Identity=38.4823848238482, Blast_Score=249, Evalue=7e-67,
Organism=Saccharomyces cerevisiae, GI6321773, Length=381, Percent_Identity=33.5958005249344, Blast_Score=195, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6321649, Length=144, Percent_Identity=40.2777777777778, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640873, Length=372, Percent_Identity=41.1290322580645, Blast_Score=290, Evalue=9e-79,
Organism=Drosophila melanogaster, GI24640877, Length=372, Percent_Identity=41.1290322580645, Blast_Score=290, Evalue=9e-79,
Organism=Drosophila melanogaster, GI24640875, Length=372, Percent_Identity=41.1290322580645, Blast_Score=290, Evalue=9e-79,
Organism=Drosophila melanogaster, GI24640879, Length=334, Percent_Identity=38.622754491018, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24585318, Length=204, Percent_Identity=28.4313725490196, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39512; Mature: 39381

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPVPDLRLDVLAKIVNP
CCEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCHHHHHHHHCCC
ERVLPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIGHVVRCFEDDNIIHVAGKIS
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCC
PIEDIEIINLELALADLDSCERAILRQAKKAKGGDQTAKFEISVLEKLLPVFTEGGMART
CCCCEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCCEEE
VELSKEEVAAVSYLNFLTLKPTMYIANVAEDGFENNPFLDLVRDYATAENNVVVAVCAAI
EECCHHHHHHHHHHHHEEECCCEEEEEHHHCCCCCCCHHHHHHHHHCCCCCEEEEEHHHH
ESELSELDDEDREEFFADMGIEEPGLNRVIRSGYDLLALQTYFTAGVKEVRAWTIPVGAT
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHCHHHHEEEEEECCCC
APQAAGKIHTDFEKGFIRAEVVGYDNFIEFSGESGAKEAGKWRLEGKDYIVKDGDVVHFR
CCCCCCCEECHHHHCEEEEEEECCCCEEEECCCCCCCCCCCEEECCCEEEEECCCEEEEE
FNV
ECC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPVPDLRLDVLAKIVNP
CEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCHHHHHHHHCCC
ERVLPTTMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIGHVVRCFEDDNIIHVAGKIS
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCC
PIEDIEIINLELALADLDSCERAILRQAKKAKGGDQTAKFEISVLEKLLPVFTEGGMART
CCCCEEEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCCEEE
VELSKEEVAAVSYLNFLTLKPTMYIANVAEDGFENNPFLDLVRDYATAENNVVVAVCAAI
EECCHHHHHHHHHHHHEEECCCEEEEEHHHCCCCCCCHHHHHHHHHCCCCCEEEEEHHHH
ESELSELDDEDREEFFADMGIEEPGLNRVIRSGYDLLALQTYFTAGVKEVRAWTIPVGAT
HHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHCHHHHEEEEEECCCC
APQAAGKIHTDFEKGFIRAEVVGYDNFIEFSGESGAKEAGKWRLEGKDYIVKDGDVVHFR
CCCCCCCEECHHHHCEEEEEEECCCCEEEECCCCCCCCCCCEEECCCEEEEECCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA