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The map label for this gene is engA

Identifier: 209694322

GI number: 209694322

Start: 816940

End: 818442

Strand: Direct

Name: engA

Synonym: VSAL_I0733

Alternate gene names: 209694322

Gene position: 816940-818442 (Clockwise)

Preceding gene: 209694321

Following gene: 209694323

Centisome position: 24.57

GC content: 40.39

Gene sequence:

>1503_bases
ATGATTCCTGTTGTTGCTCTGGTAGGGCGTCCAAATGTTGGTAAGTCGACGCTGTTTAACCGTGTTACACGCACAAGGGA
TGCATTAGTTGCTGACTTTCCAGGCTTAACGCGTGACCGTAAATATGGTCGAGCTAAGTTAGAAGAGCAAGAATTCATTC
TAATCGATACCGGCGGTATTGATGGAACAGAAGAAGGTGTTGAAACTAAAATGGCTGAACAGTCATTAGCTGCGATTGAA
GAAGCTGATGTTGTGCTATTTATGGTTGATGGCCGTGCTGGTTTGACATCATCTGATGAAGCGATAGCAAAACACTTACG
TTCTCGTGAAAAACCAACATTCTTAGTCGTAAACAAGATTGATGGTATTGATGCAGATGCGGCAAGTGCTGAGTTCTGGC
AATTAGGTATGAGTAAAGTATACCAAATCGCCGCTTCACACGGTCGTGGTGTCACTTCTCTGCTTGAGCTTGCTCTTGCA
CCTTTTATGGAAGAGCTTGTTGAAGAATCTTTAAGAGATGAAAACGGTGAGATTACTGATCTGACTGAATTTGAAGATTT
TGAAGACGAAGAAAAAGATCTTACAGAAGAAGATGCAGAGAAAGATTTTGCTCGTCTTCAAGATCAACCAATCAAACTTG
CTATTATCGGTCGTCCTAACGTAGGTAAATCAACGCTAATTAACCGTATTTTAGGTGAAGAGCGTGTGGTTGTTTACGAT
ATGCCAGGTACAACTCGTGACTCTATTTACATTCCAATGGAACGTGAAGGTCAAGAATATGTACTGATCGATACTGCGGG
TGTTCGTCGTCGCGGTCGTATCAATGAAACCGTTGAAAAATTCTCAGTAATCAAAACATTGAAAGCAATCGAAGATGCTA
ACGTTGTTTTATTGGTTATTGATGCGCGTGAAAATATTTCAGATCAAGATCTAAGCTTGTTAGGCTTTGCATTGAACGCG
GGTCGTTCTTTAGTTATTGCTGTTAATAAGTGGGATGGATTGAATAATGAAGTTAAAGAGAAAGTAAAATCAGAACTAGA
CCGTCGTTTAGGTTTTGTTGACTTTGCTCGTCTTCACTTTATTTCAGCATTGCATGGTACGGGTGTTGGTCATTTATATG
AATCAGTACAAGAAGCCTATGTTTCTGCAACTAAGCGTGTAGGTACATCTGTTCTTACTCGTGTTATGAAGATGGCTCAA
GATGATCACCAACCGCCAATGGTTCGTGGCCGTCGTGTGAAATTGAAATACGCGCACGCTGGTGGTTATAACCCACCACT
TATCGTTATTCACGGTAACCAAGTAAAAGAATTACCTTCTTCTTACAAACGTTTCTTAATGAACTACTTCCGTAAATCAT
TAGAAATCATGGGAACACCAATTCGTATTCAATTCCAGAACAGCGAAAACCCATTTGAAGATCGCGGTGGTAAATTAACA
TTGTCTCAAGAGCGTCAACGTAAACGTCTTGTTGGTGCTGTTAAAAACCGCAATAAAAAATAA

Upstream 100 bases:

>100_bases
AATCCAATTTGGTGATGGTTTTTATCCGTTCATATTAAAAAAACTATCATCAAATTGGTATTAGCTCGCGCTATGCCTAT
GATTAAATTAAGAGGTATAT

Downstream 100 bases:

>100_bases
ATTCAACTAAACGATAAACGCCCAATTAATTGGGCGTTTTTTTAGGTAAAAATCATGACTCAATTCTTTTCAACGGATGT
TTTATTCTGTCATCAAACGT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MIPVVALVGRPNVGKSTLFNRVTRTRDALVADFPGLTRDRKYGRAKLEEQEFILIDTGGIDGTEEGVETKMAEQSLAAIE
EADVVLFMVDGRAGLTSSDEAIAKHLRSREKPTFLVVNKIDGIDADAASAEFWQLGMSKVYQIAASHGRGVTSLLELALA
PFMEELVEESLRDENGEITDLTEFEDFEDEEKDLTEEDAEKDFARLQDQPIKLAIIGRPNVGKSTLINRILGEERVVVYD
MPGTTRDSIYIPMEREGQEYVLIDTAGVRRRGRINETVEKFSVIKTLKAIEDANVVLLVIDARENISDQDLSLLGFALNA
GRSLVIAVNKWDGLNNEVKEKVKSELDRRLGFVDFARLHFISALHGTGVGHLYESVQEAYVSATKRVGTSVLTRVMKMAQ
DDHQPPMVRGRRVKLKYAHAGGYNPPLIVIHGNQVKELPSSYKRFLMNYFRKSLEIMGTPIRIQFQNSENPFEDRGGKLT
LSQERQRKRLVGAVKNRNKK

Sequences:

>Translated_500_residues
MIPVVALVGRPNVGKSTLFNRVTRTRDALVADFPGLTRDRKYGRAKLEEQEFILIDTGGIDGTEEGVETKMAEQSLAAIE
EADVVLFMVDGRAGLTSSDEAIAKHLRSREKPTFLVVNKIDGIDADAASAEFWQLGMSKVYQIAASHGRGVTSLLELALA
PFMEELVEESLRDENGEITDLTEFEDFEDEEKDLTEEDAEKDFARLQDQPIKLAIIGRPNVGKSTLINRILGEERVVVYD
MPGTTRDSIYIPMEREGQEYVLIDTAGVRRRGRINETVEKFSVIKTLKAIEDANVVLLVIDARENISDQDLSLLGFALNA
GRSLVIAVNKWDGLNNEVKEKVKSELDRRLGFVDFARLHFISALHGTGVGHLYESVQEAYVSATKRVGTSVLTRVMKMAQ
DDHQPPMVRGRRVKLKYAHAGGYNPPLIVIHGNQVKELPSSYKRFLMNYFRKSLEIMGTPIRIQFQNSENPFEDRGGKLT
LSQERQRKRLVGAVKNRNKK
>Mature_500_residues
MIPVVALVGRPNVGKSTLFNRVTRTRDALVADFPGLTRDRKYGRAKLEEQEFILIDTGGIDGTEEGVETKMAEQSLAAIE
EADVVLFMVDGRAGLTSSDEAIAKHLRSREKPTFLVVNKIDGIDADAASAEFWQLGMSKVYQIAASHGRGVTSLLELALA
PFMEELVEESLRDENGEITDLTEFEDFEDEEKDLTEEDAEKDFARLQDQPIKLAIIGRPNVGKSTLINRILGEERVVVYD
MPGTTRDSIYIPMEREGQEYVLIDTAGVRRRGRINETVEKFSVIKTLKAIEDANVVLLVIDARENISDQDLSLLGFALNA
GRSLVIAVNKWDGLNNEVKEKVKSELDRRLGFVDFARLHFISALHGTGVGHLYESVQEAYVSATKRVGTSVLTRVMKMAQ
DDHQPPMVRGRRVKLKYAHAGGYNPPLIVIHGNQVKELPSSYKRFLMNYFRKSLEIMGTPIRIQFQNSENPFEDRGGKLT
LSQERQRKRLVGAVKNRNKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=499, Percent_Identity=73.74749498998, Blast_Score=738, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=133, Percent_Identity=34.5864661654135, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788919, Length=124, Percent_Identity=32.258064516129, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=125, Percent_Identity=32, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=205, Percent_Identity=27.8048780487805, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_ALISL (B6EGZ1)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262250.1
- GeneID:   6989432
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I0733
- HOGENOM:   HBG592135
- OMA:   KCEKAFD
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 56062; Mature: 56062

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVVALVGRPNVGKSTLFNRVTRTRDALVADFPGLTRDRKYGRAKLEEQEFILIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCEEEEECCCC
DGTEEGVETKMAEQSLAAIEEADVVLFMVDGRAGLTSSDEAIAKHLRSREKPTFLVVNKI
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEECC
DGIDADAASAEFWQLGMSKVYQIAASHGRGVTSLLELALAPFMEELVEESLRDENGEITD
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LTEFEDFEDEEKDLTEEDAEKDFARLQDQPIKLAIIGRPNVGKSTLINRILGEERVVVYD
CCCCCCCCCHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEE
MPGTTRDSIYIPMEREGQEYVLIDTAGVRRRGRINETVEKFSVIKTLKAIEDANVVLLVI
CCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
DARENISDQDLSLLGFALNAGRSLVIAVNKWDGLNNEVKEKVKSELDRRLGFVDFARLHF
ECCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
ISALHGTGVGHLYESVQEAYVSATKRVGTSVLTRVMKMAQDDHQPPMVRGRRVKLKYAHA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEC
GGYNPPLIVIHGNQVKELPSSYKRFLMNYFRKSLEIMGTPIRIQFQNSENPFEDRGGKLT
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCEEE
LSQERQRKRLVGAVKNRNKK
EHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIPVVALVGRPNVGKSTLFNRVTRTRDALVADFPGLTRDRKYGRAKLEEQEFILIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCEEEEECCCC
DGTEEGVETKMAEQSLAAIEEADVVLFMVDGRAGLTSSDEAIAKHLRSREKPTFLVVNKI
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEECC
DGIDADAASAEFWQLGMSKVYQIAASHGRGVTSLLELALAPFMEELVEESLRDENGEITD
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LTEFEDFEDEEKDLTEEDAEKDFARLQDQPIKLAIIGRPNVGKSTLINRILGEERVVVYD
CCCCCCCCCHHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEE
MPGTTRDSIYIPMEREGQEYVLIDTAGVRRRGRINETVEKFSVIKTLKAIEDANVVLLVI
CCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
DARENISDQDLSLLGFALNAGRSLVIAVNKWDGLNNEVKEKVKSELDRRLGFVDFARLHF
ECCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
ISALHGTGVGHLYESVQEAYVSATKRVGTSVLTRVMKMAQDDHQPPMVRGRRVKLKYAHA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEC
GGYNPPLIVIHGNQVKELPSSYKRFLMNYFRKSLEIMGTPIRIQFQNSENPFEDRGGKLT
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCEEE
LSQERQRKRLVGAVKNRNKK
EHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA