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The map label for this gene is hscB

Identifier: 209694309

GI number: 209694309

Start: 804387

End: 804902

Strand: Direct

Name: hscB

Synonym: VSAL_I0720

Alternate gene names: 209694309

Gene position: 804387-804902 (Clockwise)

Preceding gene: 209694308

Following gene: 209694310

Centisome position: 24.19

GC content: 39.34

Gene sequence:

>516_bases
ATGAATCATTTTGAATTATTTGGGCTACCAAACCAGTTTGAACTGGATGGTGGCCTTCTTTCTGCTCAGTTCCTTGAATT
GCAGAAACGATTCCACCCCGACAATTTCGCGACCTCTTCAGAGCGTGACCGCTTGCTTTCCGTTCAAAAAGCGGCACAAA
TCAACGACGCTTATCAAACGCTTAAAAATCCAGTCACTCGTGCAGAGTATATATTATCAGAGCAAGGACATGACATTCGT
GGTGAACAAACCACAATGCAAGATCCTATGTTTCTAATGCAACAGATGGAGTTACGAGAAGATCTCGAAGACTTGCTATC
AAGTTCAGATCCTGAAAGTGCACTGTTTGATTTTTCAGAAAATGTTTCTGCAATGCGTAAAACTCAATTAGCTGAATTAA
AGCAGCAATTAGAATCAGAGTTATGGCAAGAAGCGGCACAAAGCGTTCGTAAACTTAAGTTTATTGATAAGCTAAACCAA
GAAGTCGAAAAGTTAGAAGATAAATTATTAGGTTAA

Upstream 100 bases:

>100_bases
CAAAGAAGGTCTAAATGAAGGCTTCAAGTTCAACAACCCTAACGTAAAAAGTGAATGTGGGTGTGGTGAAAGCTTCAACG
TATAGAGCATAACGTTAACT

Downstream 100 bases:

>100_bases
TCTTTGTTAGATTAACTAAGTGAAGGATATTACCGATGGCATTTCTACAAATTTCTGAACCTGGACAAAGTGCTGCACCG
CATCAACATAAGTTAGCGGT

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MNHFELFGLPNQFELDGGLLSAQFLELQKRFHPDNFATSSERDRLLSVQKAAQINDAYQTLKNPVTRAEYILSEQGHDIR
GEQTTMQDPMFLMQQMELREDLEDLLSSSDPESALFDFSENVSAMRKTQLAELKQQLESELWQEAAQSVRKLKFIDKLNQ
EVEKLEDKLLG

Sequences:

>Translated_171_residues
MNHFELFGLPNQFELDGGLLSAQFLELQKRFHPDNFATSSERDRLLSVQKAAQINDAYQTLKNPVTRAEYILSEQGHDIR
GEQTTMQDPMFLMQQMELREDLEDLLSSSDPESALFDFSENVSAMRKTQLAELKQQLESELWQEAAQSVRKLKFIDKLNQ
EVEKLEDKLLG
>Mature_171_residues
MNHFELFGLPNQFELDGGLLSAQFLELQKRFHPDNFATSSERDRLLSVQKAAQINDAYQTLKNPVTRAEYILSEQGHDIR
GEQTTMQDPMFLMQQMELREDLEDLLSSSDPESALFDFSENVSAMRKTQLAELKQQLESELWQEAAQSVRKLKFIDKLNQ
EVEKLEDKLLG

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Homo sapiens, GI50301234, Length=162, Percent_Identity=25.3086419753086, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1788876, Length=170, Percent_Identity=46.4705882352941, Blast_Score=155, Evalue=2e-39,
Organism=Drosophila melanogaster, GI161084223, Length=104, Percent_Identity=33.6538461538462, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSCB_ALISL (B6EGX8)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262237.1
- GeneID:   6988721
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I0720
- HOGENOM:   HBG751004
- OMA:   LNDAYQT
- ProtClustDB:   PRK05014
- HAMAP:   MF_00682
- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:1.20.1280.20
- SMART:   SM00271
- TIGRFAMs:   TIGR00714

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C; SSF46565 DnaJ_N; SSF47144 HSC20_C

EC number: NA

Molecular weight: Translated: 19782; Mature: 19782

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHFELFGLPNQFELDGGLLSAQFLELQKRFHPDNFATSSERDRLLSVQKAAQINDAYQT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LKNPVTRAEYILSEQGHDIRGEQTTMQDPMFLMQQMELREDLEDLLSSSDPESALFDFSE
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
NVSAMRKTQLAELKQQLESELWQEAAQSVRKLKFIDKLNQEVEKLEDKLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNHFELFGLPNQFELDGGLLSAQFLELQKRFHPDNFATSSERDRLLSVQKAAQINDAYQT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LKNPVTRAEYILSEQGHDIRGEQTTMQDPMFLMQQMELREDLEDLLSSSDPESALFDFSE
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
NVSAMRKTQLAELKQQLESELWQEAAQSVRKLKFIDKLNQEVEKLEDKLLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA