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The map label for this gene is bglK [H]

Identifier: 209694295

GI number: 209694295

Start: 793275

End: 794210

Strand: Direct

Name: bglK [H]

Synonym: VSAL_I0706

Alternate gene names: 209694295

Gene position: 793275-794210 (Clockwise)

Preceding gene: 209694294

Following gene: 209694296

Centisome position: 23.86

GC content: 32.16

Gene sequence:

>936_bases
ATGGCAACGTATTTATCGTTTGATATTGGTGGAACAGACATTAAGTTTGGCGTGTTGAATGAACACGGCCACATTCTAGA
TCAAGGCAAGGTGCAAACTGAGTCAAGTGGGGATCAAATCATTCAAACCATTGTTGATATAAAAGAGCAATGGTCTACAC
GATATACGTTTGATGGTGCGGCTTTCTCATTACCTGGTTTTGTTGATGTAAACACGGGGTATTTAAAAACCGGTGGAGCC
ATTGATGATTTTTATGGATTTCAATTTAAAGAGGTAATGGTTGCAAAATTGTCATTACCGGTTGAATTAGAAAATGACGT
TAATTGTGTGGCTTTAGCTGAAAAGTGGCTTGGTAAAGCACAATCGGTTGATAATTTCATCTGCATTACGATAGGCACAG
GTATCGGTGGTGCTATCTATATCAATAATCAAATGGTTCGAGGTCATGGTTTCATGGCAGGTGAATTTGGTTATATGTTC
ACAAAAAATATATTTGATACTAAAGATAAAACGACAGCAACAATGAGTTTTACTGCATCAGTAAGAGAAGGACTTAGGCG
TCGATATTCTAAATTAAAGAATATTAATAGTATTGAAAACTTATCAGGAAAGGATATATTTAAATTAGCGGATTCTGGAG
ATAATATTGCAATTAATATTATTGATGACTTTTATAAGAATATAGCCATTGGCTTATATAATTTAACGTTTATTTTAAAT
CCAGAGAAAATAATCATTGGTGGTGCAATAAGTAATCGAGATGATTTAATTTCAAATATAGAAAATAAATTTGAAGAGAT
TATACAAACTCAACCATCAATAAATAAATTTAATGTTAAAGAGTTAGTTGCTATTGAAAAAAGTACGTTTAATAATGACA
GCGGATTAATTGGATCTGTGTATCACTTTTTATCAATGACCAATCAAATTAAATAG

Upstream 100 bases:

>100_bases
TAGAGCGTAAGAAAAAAGCGTCTTTCCATTGGTTTAAAGATGTTATCGCGACTCGTGGTGAAAATATCTAGCGTTATATT
AGAAATGGGAAAGTCGAATT

Downstream 100 bases:

>100_bases
GAATAAAGCGATGTTAGTCGGTGAAGAACTAGAAAGCACGGTAATGGAACTGATCATTAATGCTGGTGAATCAAAATCAT
GCGCAATGGAAGCACTTCGA

Product: glucokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MATYLSFDIGGTDIKFGVLNEHGHILDQGKVQTESSGDQIIQTIVDIKEQWSTRYTFDGAAFSLPGFVDVNTGYLKTGGA
IDDFYGFQFKEVMVAKLSLPVELENDVNCVALAEKWLGKAQSVDNFICITIGTGIGGAIYINNQMVRGHGFMAGEFGYMF
TKNIFDTKDKTTATMSFTASVREGLRRRYSKLKNINSIENLSGKDIFKLADSGDNIAINIIDDFYKNIAIGLYNLTFILN
PEKIIIGGAISNRDDLISNIENKFEEIIQTQPSINKFNVKELVAIEKSTFNNDSGLIGSVYHFLSMTNQIK

Sequences:

>Translated_311_residues
MATYLSFDIGGTDIKFGVLNEHGHILDQGKVQTESSGDQIIQTIVDIKEQWSTRYTFDGAAFSLPGFVDVNTGYLKTGGA
IDDFYGFQFKEVMVAKLSLPVELENDVNCVALAEKWLGKAQSVDNFICITIGTGIGGAIYINNQMVRGHGFMAGEFGYMF
TKNIFDTKDKTTATMSFTASVREGLRRRYSKLKNINSIENLSGKDIFKLADSGDNIAINIIDDFYKNIAIGLYNLTFILN
PEKIIIGGAISNRDDLISNIENKFEEIIQTQPSINKFNVKELVAIEKSTFNNDSGLIGSVYHFLSMTNQIK
>Mature_310_residues
ATYLSFDIGGTDIKFGVLNEHGHILDQGKVQTESSGDQIIQTIVDIKEQWSTRYTFDGAAFSLPGFVDVNTGYLKTGGAI
DDFYGFQFKEVMVAKLSLPVELENDVNCVALAEKWLGKAQSVDNFICITIGTGIGGAIYINNQMVRGHGFMAGEFGYMFT
KNIFDTKDKTTATMSFTASVREGLRRRYSKLKNINSIENLSGKDIFKLADSGDNIAINIIDDFYKNIAIGLYNLTFILNP
EKIIIGGAISNRDDLISNIENKFEEIIQTQPSINKFNVKELVAIEKSTFNNDSGLIGSVYHFLSMTNQIK

Specific function: Catalyzes the ATP-dependent phosphorylation of cellobiose to produce cellobiose-6'-P. May have a dual role of kinase and transcriptional regulator of the cellobiose-PTS operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=269, Percent_Identity=23.7918215613383, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4885285, Length=269, Percent_Identity=23.7918215613383, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI298566325, Length=269, Percent_Identity=23.7918215613383, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI190014632, Length=269, Percent_Identity=23.7918215613383, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1787363, Length=313, Percent_Identity=23.6421725239617, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.85 [H]

Molecular weight: Translated: 34495; Mature: 34363

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYLSFDIGGTDIKFGVLNEHGHILDQGKVQTESSGDQIIQTIVDIKEQWSTRYTFDGA
CCEEEEEECCCCEEEEEEECCCCCEECCCCEECCCCHHHHHHHHHHHHHHCCCEEEECCC
AFSLPGFVDVNTGYLKTGGAIDDFYGFQFKEVMVAKLSLPVELENDVNCVALAEKWLGKA
EECCCCEEECCCCEEECCCCCHHHCCCHHHHHHHHHHCCCEEECCCCCCEEEHHHHCCCC
QSVDNFICITIGTGIGGAIYINNQMVRGHGFMAGEFGYMFTKNIFDTKDKTTATMSFTAS
CCCCCEEEEEEECCCCEEEEECCEEEECCCEEEECCCHHEECCCCCCCCCCEEEEEEHHH
VREGLRRRYSKLKNINSIENLSGKDIFKLADSGDNIAINIIDDFYKNIAIGLYNLTFILN
HHHHHHHHHHHHCCCCHHHCCCCCCEEEEECCCCEEEEEEHHHHHHHHEEEEEEEEEEEC
PEKIIIGGAISNRDDLISNIENKFEEIIQTQPSINKFNVKELVAIEKSTFNNDSGLIGSV
CCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEHHCCCCCCCCHHHHH
YHFLSMTNQIK
HHHHHHHHCCC
>Mature Secondary Structure 
ATYLSFDIGGTDIKFGVLNEHGHILDQGKVQTESSGDQIIQTIVDIKEQWSTRYTFDGA
CEEEEEECCCCEEEEEEECCCCCEECCCCEECCCCHHHHHHHHHHHHHHCCCEEEECCC
AFSLPGFVDVNTGYLKTGGAIDDFYGFQFKEVMVAKLSLPVELENDVNCVALAEKWLGKA
EECCCCEEECCCCEEECCCCCHHHCCCHHHHHHHHHHCCCEEECCCCCCEEEHHHHCCCC
QSVDNFICITIGTGIGGAIYINNQMVRGHGFMAGEFGYMFTKNIFDTKDKTTATMSFTAS
CCCCCEEEEEEECCCCEEEEECCEEEECCCEEEECCCHHEECCCCCCCCCCEEEEEEHHH
VREGLRRRYSKLKNINSIENLSGKDIFKLADSGDNIAINIIDDFYKNIAIGLYNLTFILN
HHHHHHHHHHHHCCCCHHHCCCCCCEEEEECCCCEEEEEEHHHHHHHHEEEEEEEEEEEC
PEKIIIGGAISNRDDLISNIENKFEEIIQTQPSINKFNVKELVAIEKSTFNNDSGLIGSV
CCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEHHCCCCCCCCHHHHH
YHFLSMTNQIK
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669; 12110692 [H]