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The map label for this gene is pheA [H]

Identifier: 209694251

GI number: 209694251

Start: 733504

End: 734679

Strand: Reverse

Name: pheA [H]

Synonym: VSAL_I0661

Alternate gene names: 209694251

Gene position: 734679-733504 (Counterclockwise)

Preceding gene: 209694252

Following gene: 209694250

Centisome position: 22.09

GC content: 36.14

Gene sequence:

>1176_bases
ATGACTGACACTCACTATTCCCTTGACGATATACGTTTACGCCTTAATGATCTTGATAATGAATTATTAAAGCTATTTTC
TGAACGTCGTAAACTCAGTCTAAAAGTAGCAAAAAGCAAAGTTCAAACTTCAAAGCCTGTGCGTGATTCAAAACGCGAAC
AGCAATTATTGGTAAAATTAATTAAAAATGGCAAAGCATTCGATTTAGATGCGCATTATATAACTCAAATTTTTCATACC
ATTATTGAAGATTCCGTCTTACTGCAACAAGAATACTTCCAAAATTTAGCCAATCCAGAATTAAGTCGAAAGCCGATAGC
CAGGGTTGCCTATCTTGGTTCTAAAGGATCTTATTCAAACCTAGCTAGTCGTCGTTATTTTAGTAAGAAAAATACTGAAT
TAGCTGAATTAGGTTGTGAAAACTTTAGGGAAGTCATTAAGACTGTTGAATCAGGCCACGCTGATTACGGAGTATTACCA
ATTGAGAATACGAGCTCAGGCTCAATTAACGAGGTCTATGACCTACTGCAACATACCAGTTTATACATCGTTGGTGAGTT
AACTCAAAAAATAGACCATTGCTTGCTAACGACTTCTGAAACGTCGTTAGAGCAAATAACAACACTCTACTCACACCCTC
AACCACATCAGCAATGTAGTGAGTTTCTAAATCGTTTAGATAACGTAGAACTCATTTCTTGCTCAAGCACTGCTGATGCC
ATGATTATGGTCAAAGATATTAATTCACCGACGGTTGCTGCTATCGGAAACTCCGACAGTGGTAAATTATATAGCTTACA
ACAACTCATTACTAACATCTCAAATCAAACCGAAAATCAAACTCGATTCATTGTTGTGGCAAGAAAACCGGTTGATGTTT
CGGAACAAATACCAGCGAAAACGACATTAATTATGTCTACTTCACAAGATGCAGGCTCACTTGTTGAATCTTTACTTGTT
CTAAGAAAATACGGTATTAATATGACGAAATTAGAGTCTCGTCCTATCATGGGGAATCCGTGGGAAGAAATGTTTTATAT
TGATTTAGAAGCCCATTTAAAATCAGATGCAATGAATTCAGCCATTGAAGAACTAACGTCAATTACACAATATTTAAAAG
TTCTTGGTTGCTATCCAATAGAGAATGTAACTCCGACAACTATCCCTTTAACTTAA

Upstream 100 bases:

>100_bases
TTTCTGAAACAGCGCTCATTTGAGCGCTGTTTTTTCTTGACGCAAACTTACCTCTTCCTTTATTGTGAATTAACTCTTAA
TTTACTAGGTTTGCTTATCC

Downstream 100 bases:

>100_bases
TAATTGGATGCAGAAAATGAATGTGATTATTGCCTCTTTGAACCCCGCAAAAATAAATGCAGTAAAAGCGGCATTTACTT
TAGTTTTTCCTGATACCACT

Product: P-protein (includes: chorismate mutase and prephenate dehydratase)

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTDTHYSLDDIRLRLNDLDNELLKLFSERRKLSLKVAKSKVQTSKPVRDSKREQQLLVKLIKNGKAFDLDAHYITQIFHT
IIEDSVLLQQEYFQNLANPELSRKPIARVAYLGSKGSYSNLASRRYFSKKNTELAELGCENFREVIKTVESGHADYGVLP
IENTSSGSINEVYDLLQHTSLYIVGELTQKIDHCLLTTSETSLEQITTLYSHPQPHQQCSEFLNRLDNVELISCSSTADA
MIMVKDINSPTVAAIGNSDSGKLYSLQQLITNISNQTENQTRFIVVARKPVDVSEQIPAKTTLIMSTSQDAGSLVESLLV
LRKYGINMTKLESRPIMGNPWEEMFYIDLEAHLKSDAMNSAIEELTSITQYLKVLGCYPIENVTPTTIPLT

Sequences:

>Translated_391_residues
MTDTHYSLDDIRLRLNDLDNELLKLFSERRKLSLKVAKSKVQTSKPVRDSKREQQLLVKLIKNGKAFDLDAHYITQIFHT
IIEDSVLLQQEYFQNLANPELSRKPIARVAYLGSKGSYSNLASRRYFSKKNTELAELGCENFREVIKTVESGHADYGVLP
IENTSSGSINEVYDLLQHTSLYIVGELTQKIDHCLLTTSETSLEQITTLYSHPQPHQQCSEFLNRLDNVELISCSSTADA
MIMVKDINSPTVAAIGNSDSGKLYSLQQLITNISNQTENQTRFIVVARKPVDVSEQIPAKTTLIMSTSQDAGSLVESLLV
LRKYGINMTKLESRPIMGNPWEEMFYIDLEAHLKSDAMNSAIEELTSITQYLKVLGCYPIENVTPTTIPLT
>Mature_390_residues
TDTHYSLDDIRLRLNDLDNELLKLFSERRKLSLKVAKSKVQTSKPVRDSKREQQLLVKLIKNGKAFDLDAHYITQIFHTI
IEDSVLLQQEYFQNLANPELSRKPIARVAYLGSKGSYSNLASRRYFSKKNTELAELGCENFREVIKTVESGHADYGVLPI
ENTSSGSINEVYDLLQHTSLYIVGELTQKIDHCLLTTSETSLEQITTLYSHPQPHQQCSEFLNRLDNVELISCSSTADAM
IMVKDINSPTVAAIGNSDSGKLYSLQQLITNISNQTENQTRFIVVARKPVDVSEQIPAKTTLIMSTSQDAGSLVESLLVL
RKYGINMTKLESRPIMGNPWEEMFYIDLEAHLKSDAMNSAIEELTSITQYLKVLGCYPIENVTPTTIPLT

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=378, Percent_Identity=55.026455026455, Blast_Score=421, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6324013, Length=306, Percent_Identity=24.1830065359477, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 44060; Mature: 43929

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTHYSLDDIRLRLNDLDNELLKLFSERRKLSLKVAKSKVQTSKPVRDSKREQQLLVKL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IKNGKAFDLDAHYITQIFHTIIEDSVLLQQEYFQNLANPELSRKPIARVAYLGSKGSYSN
HHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEECCCCCHHH
LASRRYFSKKNTELAELGCENFREVIKTVESGHADYGVLPIENTSSGSINEVYDLLQHTS
HHHHHHHHCCCCHHHHHCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCC
LYIVGELTQKIDHCLLTTSETSLEQITTLYSHPQPHQQCSEFLNRLDNVELISCSSTADA
EEEEHHHHHHHHHHEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCE
MIMVKDINSPTVAAIGNSDSGKLYSLQQLITNISNQTENQTRFIVVARKPVDVSEQIPAK
EEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHCCCCC
TTLIMSTSQDAGSLVESLLVLRKYGINMTKLESRPIMGNPWEEMFYIDLEAHLKSDAMNS
EEEEEECCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHEEEEEHHHHHHHHHHHH
AIEELTSITQYLKVLGCYPIENVTPTTIPLT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDTHYSLDDIRLRLNDLDNELLKLFSERRKLSLKVAKSKVQTSKPVRDSKREQQLLVKL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IKNGKAFDLDAHYITQIFHTIIEDSVLLQQEYFQNLANPELSRKPIARVAYLGSKGSYSN
HHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEECCCCCHHH
LASRRYFSKKNTELAELGCENFREVIKTVESGHADYGVLPIENTSSGSINEVYDLLQHTS
HHHHHHHHCCCCHHHHHCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCC
LYIVGELTQKIDHCLLTTSETSLEQITTLYSHPQPHQQCSEFLNRLDNVELISCSSTADA
EEEEHHHHHHHHHHEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCE
MIMVKDINSPTVAAIGNSDSGKLYSLQQLITNISNQTENQTRFIVVARKPVDVSEQIPAK
EEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHCCCCC
TTLIMSTSQDAGSLVESLLVLRKYGINMTKLESRPIMGNPWEEMFYIDLEAHLKSDAMNS
EEEEEECCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHEEEEEHHHHHHHHHHHH
AIEELTSITQYLKVLGCYPIENVTPTTIPLT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1512561; 1444388 [H]