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The map label for this gene is deoC

Identifier: 209694211

GI number: 209694211

Start: 681508

End: 682284

Strand: Direct

Name: deoC

Synonym: VSAL_I0619

Alternate gene names: 209694211

Gene position: 681508-682284 (Clockwise)

Preceding gene: 209694210

Following gene: 209694212

Centisome position: 20.5

GC content: 42.86

Gene sequence:

>777_bases
ATGAGCGATTTAAAAGCAGCTGCACTACGTGCATTAAAGTTGATGGATTTAACCACACTAAACGATAACGACACAGATGA
AGCCGTTATTGCGTTGTGTAAAAATGCGAAGACAGCCGTAGGCAATACAGCAGCAGTTTGTATCTATCCTCGTTTTGTAC
CTATTGCTAAAAAAACGCTACGTGAACAGGGGACTCCTGATGTTCGCATTGCAACGGTAACTAACTTCCCTCACGGTAAT
GATGATATTGCTATTGCGGTGGCTGAAACGAAAGCTGCGGTTGCTTATGGCGCAGACGAAGTCGATGTTGTCTTCCCATA
CCGTGCATTGATTGCTGGTAATGAAACTGTTGGTTTTGAACTGGTTAAGCAATGTAAAGAAGCGTGTGGCGATATTCTGC
TTAAAGTGATCATTGAAACTGGTGAGCTAAAAGAAGAAGCACTTATTAAGAAAACGTCTCAAATTTGTATTGAAGCAGGT
GCTAACTTCATTAAAACCTCTACTGGTAAAGTGCCAGTGAACGCAACACCAGAATATGCACGCATGATGTTAGAAGTTAT
TCGTGATATGGGCGTAGCAAAAACAGTGGGTTTCAAACCTGCTGGCGGCGTTCGTACTGCTGAAGATGCACAAGCATACC
TAGCAATGGCTGATGATATTCTAGGTGGCGATTGGGCTGATAACATGCACTACCGTTTTGGTGCGTCAAGCCTACTGACT
AATCTTTTAAATACATTAGAAGTGACAGCAGAAACAGCAGACCCATCTGCATACTAG

Upstream 100 bases:

>100_bases
ATACGCTGTTTATGTAGAACGAAAGTTCAGACAGCAACACAGTATTATGCTTAGGCATATAACAGCACTATCAAAGAATA
TTATTCTATCGGAGATAACA

Downstream 100 bases:

>100_bases
TTTCCTGTTACTCGATTTATATCGATAAATAAATCGACTTAGGTGAGGCATTACCGCTTCACCTACCTCAACCCTACCTA
TATTAATTTACCCAACCAAG

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSDLKAAALRALKLMDLTTLNDNDTDEAVIALCKNAKTAVGNTAAVCIYPRFVPIAKKTLREQGTPDVRIATVTNFPHGN
DDIAIAVAETKAAVAYGADEVDVVFPYRALIAGNETVGFELVKQCKEACGDILLKVIIETGELKEEALIKKTSQICIEAG
ANFIKTSTGKVPVNATPEYARMMLEVIRDMGVAKTVGFKPAGGVRTAEDAQAYLAMADDILGGDWADNMHYRFGASSLLT
NLLNTLEVTAETADPSAY

Sequences:

>Translated_258_residues
MSDLKAAALRALKLMDLTTLNDNDTDEAVIALCKNAKTAVGNTAAVCIYPRFVPIAKKTLREQGTPDVRIATVTNFPHGN
DDIAIAVAETKAAVAYGADEVDVVFPYRALIAGNETVGFELVKQCKEACGDILLKVIIETGELKEEALIKKTSQICIEAG
ANFIKTSTGKVPVNATPEYARMMLEVIRDMGVAKTVGFKPAGGVRTAEDAQAYLAMADDILGGDWADNMHYRFGASSLLT
NLLNTLEVTAETADPSAY
>Mature_257_residues
SDLKAAALRALKLMDLTTLNDNDTDEAVIALCKNAKTAVGNTAAVCIYPRFVPIAKKTLREQGTPDVRIATVTNFPHGND
DIAIAVAETKAAVAYGADEVDVVFPYRALIAGNETVGFELVKQCKEACGDILLKVIIETGELKEEALIKKTSQICIEAGA
NFIKTSTGKVPVNATPEYARMMLEVIRDMGVAKTVGFKPAGGVRTAEDAQAYLAMADDILGGDWADNMHYRFGASSLLTN
LLNTLEVTAETADPSAY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=254, Percent_Identity=37.7952755905512, Blast_Score=156, Evalue=2e-38,
Organism=Escherichia coli, GI1790841, Length=236, Percent_Identity=77.9661016949153, Blast_Score=382, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17533015, Length=244, Percent_Identity=38.5245901639344, Blast_Score=154, Evalue=3e-38,
Organism=Drosophila melanogaster, GI19922098, Length=258, Percent_Identity=36.8217054263566, Blast_Score=131, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_ALISL (B6ENG3)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262139.1
- ProteinModelPortal:   B6ENG3
- GeneID:   6986572
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I0619
- HOGENOM:   HBG636421
- OMA:   CKEACGD
- ProtClustDB:   PRK05283
- GO:   GO:0005737
- HAMAP:   MF_00592
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 27563; Mature: 27432

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: ACT_SITE 165-165 ACT_SITE 199-199

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLKAAALRALKLMDLTTLNDNDTDEAVIALCKNAKTAVGNTAAVCIYPRFVPIAKKTL
CCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHH
REQGTPDVRIATVTNFPHGNDDIAIAVAETKAAVAYGADEVDVVFPYRALIAGNETVGFE
HHCCCCCEEEEEEECCCCCCCCEEEEEECCCEEEEECCCCEEEEECHHHEEECCCCHHHH
LVKQCKEACGDILLKVIIETGELKEEALIKKTSQICIEAGANFIKTSTGKVPVNATPEYA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHH
RMMLEVIRDMGVAKTVGFKPAGGVRTAEDAQAYLAMADDILGGDWADNMHYRFGASSLLT
HHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHH
NLLNTLEVTAETADPSAY
HHHHHHHHEEECCCCCCC
>Mature Secondary Structure 
SDLKAAALRALKLMDLTTLNDNDTDEAVIALCKNAKTAVGNTAAVCIYPRFVPIAKKTL
CCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHH
REQGTPDVRIATVTNFPHGNDDIAIAVAETKAAVAYGADEVDVVFPYRALIAGNETVGFE
HHCCCCCEEEEEEECCCCCCCCEEEEEECCCEEEEECCCCEEEEECHHHEEECCCCHHHH
LVKQCKEACGDILLKVIIETGELKEEALIKKTSQICIEAGANFIKTSTGKVPVNATPEYA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHH
RMMLEVIRDMGVAKTVGFKPAGGVRTAEDAQAYLAMADDILGGDWADNMHYRFGASSLLT
HHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHHHH
NLLNTLEVTAETADPSAY
HHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA