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The map label for this gene is zraR [H]

Identifier: 209694159

GI number: 209694159

Start: 623013

End: 624350

Strand: Direct

Name: zraR [H]

Synonym: VSAL_I0567

Alternate gene names: 209694159

Gene position: 623013-624350 (Clockwise)

Preceding gene: 209694158

Following gene: 209694161

Centisome position: 18.74

GC content: 39.31

Gene sequence:

>1338_bases
ATGGGTACTCAGTTTCGTATGGATTCGGTTCCTGGTTCATTAGTTGTCGTTGGTGGTAGCTACGAACCTTGGTTAGCGGT
CTTAGAACAAGTAGGTTGGCGTTGTCACCGTTGTTACGACTTACGTGCAGCACAAACATTATTTGACGAAATTGGACCAT
GTATTGGGATTGTTGATTTAAGCCAAGATGATTTCAGTTTAAATGGAATTGCCACGCTAGTTAATAATAATAAACAAGTG
CGTTGGATCGCGTTTATTCGTGAATCTCAACTGGGTTCTGATACGATTTGCCAATTTATTGTGAATTTTTGTATCGACTT
TTTTACCGCTCCAATTCCTGATGCGCAGCTATTGAGTACTATCGGCCATCAACTGGGAATGCTAAAGCTTGAGCGTAAAG
TATGGCCAAATTTGGGAAATAAATCAGATTTAGGTATTTTAGGTGAGGCGCCAGCAGTGAAACGCCTAAGAGATCAGATC
CGAAGAGTTGCCCCTACCGATGTCTCTATTTTAATTTCGGGTGAGAGTGGTGTAGGTAAAGATGTCGTTGCTAAAGCGGT
GCATGATTCTTCAGGTCGTAATAAAGGTCCCTTTGTATCGCTGAACTGTGGTTCATTGTCTGAAGTGAAAATTGAACAAG
AATTATTTGGTTTGAATTCTGAATTCCCAGAAACATCAAAATTATTACAAGCCAATGGTGGTACATTATTTTTAAATGAC
ATTAATGATTTACCAGTCAGCCAACAACAACTTTTATTACGTTTTCTACAAGAAAGCAATATGGAAACGCCTCAAGGACT
TGTTGATCTTGATGTTCGAGTTATTGTTGCAAGTCATATTGATCTTGAAAAAGCGATCGAAGAAGGGGACTTCAAGGAAG
AGCTTTATTATCGCTTAAATGTATTGCGTATTCATGTACCTGCATTAAAAGAACGCAGTTCAGACATTTCGATTCTAGCA
GAGCATTTTTTACAGCGATATGCGAAAGAATATAATACTCAGGCACGTACTTTCTCAGAAGAAGCACTACAAACGATGAT
TCATTACCCATGGCCTGGTAATGTGAGAGAGCTGGTTAATCAAGTGAAACGAGCGGTATTACTTGCTGATAGTATGACGA
TTGATCTTGAGCATTTGGATCTTCCTCAGCGTAATGATACAAAACGCAGTTTACGCACAATCCGTGAAAATTCAGAACGT
GATGCTTTACTATTGGTTCTGGAATCACATGATGGTCAAGTATCATCAGCAGCGAAAGAGTTAGGGGTATCCCGTGCTAC
GATGTACCGTTTATTGAATAAACATAACCTTATTTCTGAGCCAAGAACATACAGTTAA

Upstream 100 bases:

>100_bases
GGCCATCTCGTTTGTGAGACTCGTGTTCGTCTTAAAACCTGTATAGTCGTTCTTAAGAGATATTTTAGTTGGTTTATATA
AAGAATTTAGAGGTAGTTTT

Downstream 100 bases:

>100_bases
TTCGTACAGTAAGCGAGTAACTCACTCATGTTTAAAGCCATTGTATTTATAAATACAGTGGCTTTTTTAGTTAAAAAAGG
ATGTTAATATAGAGTGGGTA

Product: sigma-54 interacting regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MGTQFRMDSVPGSLVVVGGSYEPWLAVLEQVGWRCHRCYDLRAAQTLFDEIGPCIGIVDLSQDDFSLNGIATLVNNNKQV
RWIAFIRESQLGSDTICQFIVNFCIDFFTAPIPDAQLLSTIGHQLGMLKLERKVWPNLGNKSDLGILGEAPAVKRLRDQI
RRVAPTDVSILISGESGVGKDVVAKAVHDSSGRNKGPFVSLNCGSLSEVKIEQELFGLNSEFPETSKLLQANGGTLFLND
INDLPVSQQQLLLRFLQESNMETPQGLVDLDVRVIVASHIDLEKAIEEGDFKEELYYRLNVLRIHVPALKERSSDISILA
EHFLQRYAKEYNTQARTFSEEALQTMIHYPWPGNVRELVNQVKRAVLLADSMTIDLEHLDLPQRNDTKRSLRTIRENSER
DALLLVLESHDGQVSSAAKELGVSRATMYRLLNKHNLISEPRTYS

Sequences:

>Translated_445_residues
MGTQFRMDSVPGSLVVVGGSYEPWLAVLEQVGWRCHRCYDLRAAQTLFDEIGPCIGIVDLSQDDFSLNGIATLVNNNKQV
RWIAFIRESQLGSDTICQFIVNFCIDFFTAPIPDAQLLSTIGHQLGMLKLERKVWPNLGNKSDLGILGEAPAVKRLRDQI
RRVAPTDVSILISGESGVGKDVVAKAVHDSSGRNKGPFVSLNCGSLSEVKIEQELFGLNSEFPETSKLLQANGGTLFLND
INDLPVSQQQLLLRFLQESNMETPQGLVDLDVRVIVASHIDLEKAIEEGDFKEELYYRLNVLRIHVPALKERSSDISILA
EHFLQRYAKEYNTQARTFSEEALQTMIHYPWPGNVRELVNQVKRAVLLADSMTIDLEHLDLPQRNDTKRSLRTIRENSER
DALLLVLESHDGQVSSAAKELGVSRATMYRLLNKHNLISEPRTYS
>Mature_444_residues
GTQFRMDSVPGSLVVVGGSYEPWLAVLEQVGWRCHRCYDLRAAQTLFDEIGPCIGIVDLSQDDFSLNGIATLVNNNKQVR
WIAFIRESQLGSDTICQFIVNFCIDFFTAPIPDAQLLSTIGHQLGMLKLERKVWPNLGNKSDLGILGEAPAVKRLRDQIR
RVAPTDVSILISGESGVGKDVVAKAVHDSSGRNKGPFVSLNCGSLSEVKIEQELFGLNSEFPETSKLLQANGGTLFLNDI
NDLPVSQQQLLLRFLQESNMETPQGLVDLDVRVIVASHIDLEKAIEEGDFKEELYYRLNVLRIHVPALKERSSDISILAE
HFLQRYAKEYNTQARTFSEEALQTMIHYPWPGNVRELVNQVKRAVLLADSMTIDLEHLDLPQRNDTKRSLRTIRENSERD
ALLLVLESHDGQVSSAAKELGVSRATMYRLLNKHNLISEPRTYS

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=386, Percent_Identity=34.1968911917098, Blast_Score=224, Evalue=6e-60,
Organism=Escherichia coli, GI1788905, Length=345, Percent_Identity=37.9710144927536, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1788550, Length=426, Percent_Identity=32.3943661971831, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1790299, Length=334, Percent_Identity=35.3293413173653, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI87082117, Length=321, Percent_Identity=36.4485981308411, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1786524, Length=319, Percent_Identity=35.1097178683386, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI1789233, Length=322, Percent_Identity=32.9192546583851, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789087, Length=302, Percent_Identity=34.4370860927152, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI87082152, Length=316, Percent_Identity=32.5949367088608, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787583, Length=305, Percent_Identity=33.1147540983607, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI87081872, Length=318, Percent_Identity=31.7610062893082, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI87081858, Length=300, Percent_Identity=29.6666666666667, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789828, Length=252, Percent_Identity=31.3492063492063, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49926; Mature: 49794

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTQFRMDSVPGSLVVVGGSYEPWLAVLEQVGWRCHRCYDLRAAQTLFDEIGPCIGIVDL
CCCCEECCCCCCCEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCEEEEEEC
SQDDFSLNGIATLVNNNKQVRWIAFIRESQLGSDTICQFIVNFCIDFFTAPIPDAQLLST
CCCCCCCCCEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IGHQLGMLKLERKVWPNLGNKSDLGILGEAPAVKRLRDQIRRVAPTDVSILISGESGVGK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCH
DVVAKAVHDSSGRNKGPFVSLNCGSLSEVKIEQELFGLNSEFPETSKLLQANGGTLFLND
HHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEC
INDLPVSQQQLLLRFLQESNMETPQGLVDLDVRVIVASHIDLEKAIEEGDFKEELYYRLN
CCCCCCCHHHHHHHHHHHCCCCCCCCEECCCEEEEEEHHCCHHHHHHCCCHHHHHHHHHE
VLRIHVPALKERSSDISILAEHFLQRYAKEYNTQARTFSEEALQTMIHYPWPGNVRELVN
EEEEECCHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
QVKRAVLLADSMTIDLEHLDLPQRNDTKRSLRTIRENSERDALLLVLESHDGQVSSAAKE
HHHHHHHHHCCCEEEHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHH
LGVSRATMYRLLNKHNLISEPRTYS
HCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
GTQFRMDSVPGSLVVVGGSYEPWLAVLEQVGWRCHRCYDLRAAQTLFDEIGPCIGIVDL
CCCEECCCCCCCEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCEEEEEEC
SQDDFSLNGIATLVNNNKQVRWIAFIRESQLGSDTICQFIVNFCIDFFTAPIPDAQLLST
CCCCCCCCCEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IGHQLGMLKLERKVWPNLGNKSDLGILGEAPAVKRLRDQIRRVAPTDVSILISGESGVGK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCH
DVVAKAVHDSSGRNKGPFVSLNCGSLSEVKIEQELFGLNSEFPETSKLLQANGGTLFLND
HHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEEC
INDLPVSQQQLLLRFLQESNMETPQGLVDLDVRVIVASHIDLEKAIEEGDFKEELYYRLN
CCCCCCCHHHHHHHHHHHCCCCCCCCEECCCEEEEEEHHCCHHHHHHCCCHHHHHHHHHE
VLRIHVPALKERSSDISILAEHFLQRYAKEYNTQARTFSEEALQTMIHYPWPGNVRELVN
EEEEECCHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
QVKRAVLLADSMTIDLEHLDLPQRNDTKRSLRTIRENSERDALLLVLESHDGQVSSAAKE
HHHHHHHHHCCCEEEHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHH
LGVSRATMYRLLNKHNLISEPRTYS
HCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]