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The map label for this gene is mshD [H]

Identifier: 209694066

GI number: 209694066

Start: 525107

End: 526747

Strand: Direct

Name: mshD [H]

Synonym: VSAL_I0469

Alternate gene names: 209694066

Gene position: 525107-526747 (Clockwise)

Preceding gene: 209694065

Following gene: 209694067

Centisome position: 15.79

GC content: 41.19

Gene sequence:

>1641_bases
ATGAAAGCATGTAAAATCATCGTTGGGTTAATGGTCGCTTCTTTAGCAGGTTGTTCAATGGGCCATCGAGATCCAACGGA
GATCAAACAAACCTTAGATCAATCTATTAATGATAATGGCGGTCAATTATTGGATGATCTACCTGCTTCAATACAAGCCG
ATTTAATGCCTGATTTAAACTCATCAACGGTGTCAATTGATGAGCCCGTAAAACGATTTAGAATCAAAGCGAATGGCGTG
AGTGCAAAAGCCTTTTTTACAAGCTTAGTAAAAGGCACAGAATACAGTGTGATATTGCATCCTGATGTCAGCGGTCGAAT
TACGATGAACGTAAATGAAGTGACGTTGGATGAAGTACTTCGCTCTGTTGAAGATCTTTATGGTTATGAAATCATAAAAT
CAGGCAAGGTATTGCAAGTTTATCCTGCGACGATCCGCACCGAAACGATCCCCGTTGATTATTTACAATTAACACGTAAG
GGTCGTTCTTTAACGACAATCACTACAGGGTCGATTACAAATTCAGACAGTAACTCATCGAATAGTAATGATAGTTCTAA
TTCGAATAACTCATCGTCTTCGTCATCTTCCTCCTCTGCTACTGGTGGCACTGAGATAGAAACAACGAGTGAAAGTGATT
TTTGGAAAGAACTAGAAAAAGCCGTTTCAGTCATGATAGGTAATGGTTCTGGGCGAAGTGTCGTTGTATCACCTCAAGCA
AGTGTGATCACTATTACGGCCTCTCCTGATGAATTGCGTAAAGTGAAACAGTTCTTAGGTATTTCACATAAGCGCTTACA
GCGTCAAGTAATCCTAGAAGCTAAATTATTAGAAGTGACACTCAGTGATGGTTACCAACAAGGTATTAATTGGTCTAACT
TAACGGCTGCGGTTGGAGGCACTGATATTGTTTTTGGACAAGTCCCAGGAACAACCGCCGGAGTTCTGCCTGGTATGGAT
GCTATTGGATCATTATTGGGCGGACAAACCAATATTACGGTTTCTGATGGTAATTTTTCAGCTGTATTAAGTTTTATGGA
TACTCAAGGGGATTTGAATGTGCTTTCAAGCCCGAGAGTGACGGCTGCCAACAACCAGAAAGCCGTGATCAAAGTGGGTC
GTGATGAATACTTCGTCACTGAAGTCTCTAGTGTAACTGGCAATGGTGATAATTCGAATGCATCACCAGAAGTGACATTA
ACGCCATTTTTCTCTGGTATTTCATTGGATGTTACGCCCCAAATTGATGATAAAGGGAATGTGATGCTCCACGTTCACCC
ATCCGTTATCGATGTTGAAACAGAAACAAAGATCATCGATTTAGGTGATGTTGGAGGGGTTCTTGAGCTACCGCTGGCCA
AAAGCTCTATCCGTGAATCTGATTCTGTTATCCGAGCAAAAAGCGGAGATGTCGTTGTTATTGGTGGATTGATGAAATCA
CAAACGGTTGATCAAGTATCAAAAGTTCCGTTCCTTGGTGATATTCCTGTTCTTGGGCATTTATTCCGAAATGTCAGTCA
ATTAACGACTAAAACAGAGTTAGTTATCTTGCTTAAGCCAACGGTTGTTGGGGTTGATACATGGCAAGAAGAGTTAGAAC
GCTCACGTGATCTTTTGCAAGAATGGTTTCCTGACGAGTAA

Upstream 100 bases:

>100_bases
GTTATCAATTAATGACGATAACGTATTTATTGGCCGTGCTGGTAAGCGGTGGGAACTTTCTCTATTTTCACAAGACATTA
AACATTAAGGTTTGTAGTAA

Downstream 100 bases:

>100_bases
TCGATAGATTATGTATGAATCCCATTTTGGGCTGAAGCAGCTTCCATTTACGCTTACGCCAAACACATCGCTTTTCCATG
GATTGTTGCCTCATTATGAA

Product: type IV pilus, mannose-sensitive hemagglutinin D (MSHD)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MKACKIIVGLMVASLAGCSMGHRDPTEIKQTLDQSINDNGGQLLDDLPASIQADLMPDLNSSTVSIDEPVKRFRIKANGV
SAKAFFTSLVKGTEYSVILHPDVSGRITMNVNEVTLDEVLRSVEDLYGYEIIKSGKVLQVYPATIRTETIPVDYLQLTRK
GRSLTTITTGSITNSDSNSSNSNDSSNSNNSSSSSSSSSATGGTEIETTSESDFWKELEKAVSVMIGNGSGRSVVVSPQA
SVITITASPDELRKVKQFLGISHKRLQRQVILEAKLLEVTLSDGYQQGINWSNLTAAVGGTDIVFGQVPGTTAGVLPGMD
AIGSLLGGQTNITVSDGNFSAVLSFMDTQGDLNVLSSPRVTAANNQKAVIKVGRDEYFVTEVSSVTGNGDNSNASPEVTL
TPFFSGISLDVTPQIDDKGNVMLHVHPSVIDVETETKIIDLGDVGGVLELPLAKSSIRESDSVIRAKSGDVVVIGGLMKS
QTVDQVSKVPFLGDIPVLGHLFRNVSQLTTKTELVILLKPTVVGVDTWQEELERSRDLLQEWFPDE

Sequences:

>Translated_546_residues
MKACKIIVGLMVASLAGCSMGHRDPTEIKQTLDQSINDNGGQLLDDLPASIQADLMPDLNSSTVSIDEPVKRFRIKANGV
SAKAFFTSLVKGTEYSVILHPDVSGRITMNVNEVTLDEVLRSVEDLYGYEIIKSGKVLQVYPATIRTETIPVDYLQLTRK
GRSLTTITTGSITNSDSNSSNSNDSSNSNNSSSSSSSSSATGGTEIETTSESDFWKELEKAVSVMIGNGSGRSVVVSPQA
SVITITASPDELRKVKQFLGISHKRLQRQVILEAKLLEVTLSDGYQQGINWSNLTAAVGGTDIVFGQVPGTTAGVLPGMD
AIGSLLGGQTNITVSDGNFSAVLSFMDTQGDLNVLSSPRVTAANNQKAVIKVGRDEYFVTEVSSVTGNGDNSNASPEVTL
TPFFSGISLDVTPQIDDKGNVMLHVHPSVIDVETETKIIDLGDVGGVLELPLAKSSIRESDSVIRAKSGDVVVIGGLMKS
QTVDQVSKVPFLGDIPVLGHLFRNVSQLTTKTELVILLKPTVVGVDTWQEELERSRDLLQEWFPDE
>Mature_546_residues
MKACKIIVGLMVASLAGCSMGHRDPTEIKQTLDQSINDNGGQLLDDLPASIQADLMPDLNSSTVSIDEPVKRFRIKANGV
SAKAFFTSLVKGTEYSVILHPDVSGRITMNVNEVTLDEVLRSVEDLYGYEIIKSGKVLQVYPATIRTETIPVDYLQLTRK
GRSLTTITTGSITNSDSNSSNSNDSSNSNNSSSSSSSSSATGGTEIETTSESDFWKELEKAVSVMIGNGSGRSVVVSPQA
SVITITASPDELRKVKQFLGISHKRLQRQVILEAKLLEVTLSDGYQQGINWSNLTAAVGGTDIVFGQVPGTTAGVLPGMD
AIGSLLGGQTNITVSDGNFSAVLSFMDTQGDLNVLSSPRVTAANNQKAVIKVGRDEYFVTEVSSVTGNGDNSNASPEVTL
TPFFSGISLDVTPQIDDKGNVMLHVHPSVIDVETETKIIDLGDVGGVLELPLAKSSIRESDSVIRAKSGDVVVIGGLMKS
QTVDQVSKVPFLGDIPVLGHLFRNVSQLTTKTELVILLKPTVVGVDTWQEELERSRDLLQEWFPDE

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI87082242, Length=322, Percent_Identity=26.0869565217391, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789793, Length=181, Percent_Identity=27.6243093922652, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR013356
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 58369; Mature: 58369

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKACKIIVGLMVASLAGCSMGHRDPTEIKQTLDQSINDNGGQLLDDLPASIQADLMPDLN
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHCCCCCC
SSTVSIDEPVKRFRIKANGVSAKAFFTSLVKGTEYSVILHPDVSGRITMNVNEVTLDEVL
CCEEEHHHHHHHEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCHHHHH
RSVEDLYGYEIIKSGKVLQVYPATIRTETIPVDYLQLTRKGRSLTTITTGSITNSDSNSS
HHHHHHHCCCEECCCCEEEEECCEEEECCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCC
NSNDSSNSNNSSSSSSSSSATGGTEIETTSESDFWKELEKAVSVMIGNGSGRSVVVSPQA
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHEEEEECCCCCEEEECCCC
SVITITASPDELRKVKQFLGISHKRLQRQVILEAKLLEVTLSDGYQQGINWSNLTAAVGG
CEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEECCCHHHCCCCCCEEEECCC
TDIVFGQVPGTTAGVLPGMDAIGSLLGGQTNITVSDGNFSAVLSFMDTQGDLNVLSSPRV
CEEEEECCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCEEHEEECCCCCCCEECCCCCE
TAANNQKAVIKVGRDEYFVTEVSSVTGNGDNSNASPEVTLTPFFSGISLDVTPQIDDKGN
EECCCCEEEEEECCCCEEEEEEHHCCCCCCCCCCCCEEEEEEEECCEEEEECCCCCCCCC
VMLHVHPSVIDVETETKIIDLGDVGGVLELPLAKSSIRESDSVIRAKSGDVVVIGGLMKS
EEEEECCCEEEEECCCEEEEECCCCCEEECCCCHHHHHCCCCEEEECCCCEEEECCCHHH
QTVDQVSKVPFLGDIPVLGHLFRNVSQLTTKTELVILLKPTVVGVDTWQEELERSRDLLQ
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCEEECHHHHHHHHHHHHHHH
EWFPDE
HHCCCC
>Mature Secondary Structure
MKACKIIVGLMVASLAGCSMGHRDPTEIKQTLDQSINDNGGQLLDDLPASIQADLMPDLN
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHCCCCCC
SSTVSIDEPVKRFRIKANGVSAKAFFTSLVKGTEYSVILHPDVSGRITMNVNEVTLDEVL
CCEEEHHHHHHHEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCHHHHH
RSVEDLYGYEIIKSGKVLQVYPATIRTETIPVDYLQLTRKGRSLTTITTGSITNSDSNSS
HHHHHHHCCCEECCCCEEEEECCEEEECCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCC
NSNDSSNSNNSSSSSSSSSATGGTEIETTSESDFWKELEKAVSVMIGNGSGRSVVVSPQA
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHEEEEECCCCCEEEECCCC
SVITITASPDELRKVKQFLGISHKRLQRQVILEAKLLEVTLSDGYQQGINWSNLTAAVGG
CEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHEEEEEEECCCHHHCCCCCCEEEECCC
TDIVFGQVPGTTAGVLPGMDAIGSLLGGQTNITVSDGNFSAVLSFMDTQGDLNVLSSPRV
CEEEEECCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCEEHEEECCCCCCCEECCCCCE
TAANNQKAVIKVGRDEYFVTEVSSVTGNGDNSNASPEVTLTPFFSGISLDVTPQIDDKGN
EECCCCEEEEEECCCCEEEEEEHHCCCCCCCCCCCCEEEEEEEECCEEEEECCCCCCCCC
VMLHVHPSVIDVETETKIIDLGDVGGVLELPLAKSSIRESDSVIRAKSGDVVVIGGLMKS
EEEEECCCEEEEECCCEEEEECCCCCEEECCCCHHHHHCCCCEEEECCCCEEEECCCHHH
QTVDQVSKVPFLGDIPVLGHLFRNVSQLTTKTELVILLKPTVVGVDTWQEELERSRDLLQ
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCEEECHHHHHHHHHHHHHHH
EWFPDE
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1640836 [H]