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The map label for this gene is mpg1 [H]

Identifier: 209693784

GI number: 209693784

Start: 207356

End: 208414

Strand: Reverse

Name: mpg1 [H]

Synonym: VSAL_I0167

Alternate gene names: 209693784

Gene position: 208414-207356 (Counterclockwise)

Preceding gene: 209693785

Following gene: 209693783

Centisome position: 6.27

GC content: 37.96

Gene sequence:

>1059_bases
ATGAGTTATTCTTGGAAAAAAGTATTAATTAAACCGGAATCCACCATTGTTGATGCGCTTAGAGTTATTGATAATGAATC
ATTGAGAATCGCATTAGTTGTTAATGATGAACAGCAGCTCTTAGGTGTAGTTACAGATGGTGATATTCGTAGAAGTATTT
TAAATAACTTACCTTTAGATACCCTTGTTGTAGATATCATGAGTTGCTCACCTATTACGGCATCAGTGAATACAGCAAAA
GAGCAGTTAGTTAAATTAATGGAGAGCGAAGGGATTCTTGCGATACCATTAATGGAAGAAAATAAAGTGGTAGGGCTAGA
AACGCTCCATCACTTATTTGAAGAGAAAACCTATCACAACCCTGTATTTATCATGGCAGGTGGCTTTGGTACGCGTTTGC
GTCCTCTAACAGATTCTTGCCCTAAACCCATGCTTAAAATTGGTAATAAGCCAATTTTAGAGACAGTTATTCGTAGCTTT
ATTAAAGCGGGTTTTGTAAATTTCTATATATCGACACACTATATGCCAGAGCAGATCCAGCAGCACTTTGGTGATGGATC
TGATTTAGGTGTAAAGATCAGCTATGTTCATGAAGATTTTCCGCTAGGTACTGGTGGGGCGCTTGGTTTACTTCCTGATG
ATTTACCAAAAGACCTACCATTAATCATGATGAATGGAGATGTACTTACCAAGGTCGATTTTGAACGTCTATTAGATTTC
CATACAGAAAATGAAGCCGATGCAACCATGTGTGTTCGCGAGTACGATTATCAAATCCCTTATGGCGTGATTAATGGTGA
AGGAAACAAGATTACAAGTATGGTAGAGAAACCAATTCAACGTTTCTTTGTTAATGCTGGTATTTATGTCGTGTCGCCAC
GCGTGATCCAGTCGGTTCCTGAAAATCACCATATTGATATGCCAACATTGCTAGAACAGCATATGAATGAGCGCGATAAC
ATTCTTATGTTCCCTATTCATGAATATTGGTTAGATATCGGTCGTATGGATGATTTTAATCGTGCACAAGCGGATATTCA
TACTTTGGGTGTTTTATAA

Upstream 100 bases:

>100_bases
TTCGATTGTTGGTGCGGGTGCTATAGTGACTAAAAATATATCTTCTGAACAAATCTGCTACCCAAGCCGTTCGGTATTGA
AATAAGTAATAAGGTAAGTC

Downstream 100 bases:

>100_bases
TGATTAGTAATAAAAAAATAATGGCGATTATTCCTGCTAGAGGCGGCAGTAAAAGATTACCAAGGAAAAATATACTTCCT
TTAAATGGAAAGCCTTTAAT

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSYSWKKVLIKPESTIVDALRVIDNESLRIALVVNDEQQLLGVVTDGDIRRSILNNLPLDTLVVDIMSCSPITASVNTAK
EQLVKLMESEGILAIPLMEENKVVGLETLHHLFEEKTYHNPVFIMAGGFGTRLRPLTDSCPKPMLKIGNKPILETVIRSF
IKAGFVNFYISTHYMPEQIQQHFGDGSDLGVKISYVHEDFPLGTGGALGLLPDDLPKDLPLIMMNGDVLTKVDFERLLDF
HTENEADATMCVREYDYQIPYGVINGEGNKITSMVEKPIQRFFVNAGIYVVSPRVIQSVPENHHIDMPTLLEQHMNERDN
ILMFPIHEYWLDIGRMDDFNRAQADIHTLGVL

Sequences:

>Translated_352_residues
MSYSWKKVLIKPESTIVDALRVIDNESLRIALVVNDEQQLLGVVTDGDIRRSILNNLPLDTLVVDIMSCSPITASVNTAK
EQLVKLMESEGILAIPLMEENKVVGLETLHHLFEEKTYHNPVFIMAGGFGTRLRPLTDSCPKPMLKIGNKPILETVIRSF
IKAGFVNFYISTHYMPEQIQQHFGDGSDLGVKISYVHEDFPLGTGGALGLLPDDLPKDLPLIMMNGDVLTKVDFERLLDF
HTENEADATMCVREYDYQIPYGVINGEGNKITSMVEKPIQRFFVNAGIYVVSPRVIQSVPENHHIDMPTLLEQHMNERDN
ILMFPIHEYWLDIGRMDDFNRAQADIHTLGVL
>Mature_351_residues
SYSWKKVLIKPESTIVDALRVIDNESLRIALVVNDEQQLLGVVTDGDIRRSILNNLPLDTLVVDIMSCSPITASVNTAKE
QLVKLMESEGILAIPLMEENKVVGLETLHHLFEEKTYHNPVFIMAGGFGTRLRPLTDSCPKPMLKIGNKPILETVIRSFI
KAGFVNFYISTHYMPEQIQQHFGDGSDLGVKISYVHEDFPLGTGGALGLLPDDLPKDLPLIMMNGDVLTKVDFERLLDFH
TENEADATMCVREYDYQIPYGVINGEGNKITSMVEKPIQRFFVNAGIYVVSPRVIQSVPENHHIDMPTLLEQHMNERDNI
LMFPIHEYWLDIGRMDDFNRAQADIHTLGVL

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=229, Percent_Identity=32.7510917030568, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI11761619, Length=229, Percent_Identity=32.7510917030568, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI1788351, Length=178, Percent_Identity=27.5280898876405, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI133931050, Length=233, Percent_Identity=31.3304721030043, Blast_Score=126, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320148, Length=230, Percent_Identity=34.3478260869565, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI21355443, Length=228, Percent_Identity=32.8947368421053, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24644084, Length=228, Percent_Identity=32.8947368421053, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24653912, Length=186, Percent_Identity=27.9569892473118, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 39731; Mature: 39600

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSWKKVLIKPESTIVDALRVIDNESLRIALVVNDEQQLLGVVTDGDIRRSILNNLPLD
CCCCCEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCHHHHHHHHCCCHH
TLVVDIMSCSPITASVNTAKEQLVKLMESEGILAIPLMEENKVVGLETLHHLFEEKTYHN
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCEEHHHHHHHHHHHCCCCC
PVFIMAGGFGTRLRPLTDSCPKPMLKIGNKPILETVIRSFIKAGFVNFYISTHYMPEQIQ
CEEEEECCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHCHHEEEEECCCCHHHHH
QHFGDGSDLGVKISYVHEDFPLGTGGALGLLPDDLPKDLPLIMMNGDVLTKVDFERLLDF
HHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEHHHHHHHHHH
HTENEADATMCVREYDYQIPYGVINGEGNKITSMVEKPIQRFFVNAGIYVVSPRVIQSVP
CCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEEEECCHHHHHCC
ENHHIDMPTLLEQHMNERDNILMFPIHEYWLDIGRMDDFNRAQADIHTLGVL
CCCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SYSWKKVLIKPESTIVDALRVIDNESLRIALVVNDEQQLLGVVTDGDIRRSILNNLPLD
CCCCEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCHHHHHHHHCCCHH
TLVVDIMSCSPITASVNTAKEQLVKLMESEGILAIPLMEENKVVGLETLHHLFEEKTYHN
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCEEHHHHHHHHHHHCCCCC
PVFIMAGGFGTRLRPLTDSCPKPMLKIGNKPILETVIRSFIKAGFVNFYISTHYMPEQIQ
CEEEEECCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHCHHEEEEECCCCHHHHH
QHFGDGSDLGVKISYVHEDFPLGTGGALGLLPDDLPKDLPLIMMNGDVLTKVDFERLLDF
HHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEHHHHHHHHHH
HTENEADATMCVREYDYQIPYGVINGEGNKITSMVEKPIQRFFVNAGIYVVSPRVIQSVP
CCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEEEECCHHHHHCC
ENHHIDMPTLLEQHMNERDNILMFPIHEYWLDIGRMDDFNRAQADIHTLGVL
CCCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]