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The map label for this gene is lpxK [H]

Identifier: 308535196

GI number: 308535196

Start: 1003185

End: 1004264

Strand: Direct

Name: lpxK [H]

Synonym: NA

Alternate gene names: 308535196

Gene position: 1003185-1004264 (Clockwise)

Preceding gene: 197117239

Following gene: 197117241

Centisome position: 21.74

GC content: 67.13

Gene sequence:

>1080_bases
GTGGCTGATCTGGAATCCTATTTCAAGGAATTGATGGACGGCAAGCGCGCCGGGTGGAAGGACCGGCTCGCCCTCGCCGG
ACTGCGCCTCGCTTCGCTCCCCTACGCCCTGGCGTTGAGGCTCCGCGCGCTCGGCTACGCGGCCGGCCTCATCCCGTCGC
ACCGGCTCCCACGCCCGGTCATCTCGGTGGGGAACGTCACCCTGGGGGGGACCGGCAAGACCCCGACCGTCGCCTGGCTC
GCCTCCTACCTCATCGGGCGCGGCAAGAGGGTCGCCGTTCTCTCGCGCGGCTACGGCGGGAGCGCGGAAGGAGAGCTGCG
CATCGTAAGCGACGGCAATAACCTCCTCGTGGGGCCGGAAGAGGCGGGGGACGAGCCCTGCCTTTTGGCGCGCAAGGTGC
CGGGGCTCATGGTGGTGACCGGGGCGGACCGCTACCGGGCGGGGCTTCTGGCGCTCAAGGAGCTTAACCCGGACGTCTTC
ATCCTGGACGACGGCTTCCAGCACCTGAAGCTCAAGCGCGACCTGAACCTGCTGCTTCTCGACTGCAGGCGCCCCTTCGG
CAACGACCGGGTGCTTCCGGCCGGGTACCTGCGGGAACCGAAGAGTGCCATCGGGCGCGCCGACCTGGTCCTCTTCACCC
GCTGCCAGCCCGAGAGCGCCCCGCAGCTCGCGAACCTCGCCACGCCTGCCTGCCGCTCGCTGCACCGGCTGAACGGCTGC
GCTCCTCTCAAGGGGGGGGAGCCGCTGGCTTTCTCCGACCTGAAGGGGGAGCGCTGCATGGCCTTTGCCGGCATTGCCGA
CCCGGCAGGGTTCTTCGACAGCCTGGAAAAGGAGGGGGTGCAGCTGGTGACCACCCTCGCTTTTTCGGACCACATCTGCT
ATGGTGACGCCGAAATTGCGGCCGTTTTGCGCCTGAAAAAGGCATCTCGGTCGGCTTTCATGGTGACGACGGAGAAGGAC
GCGGTGAAGCTCGCCCCCTTCATGGACCAACTGGGGACCGTCTACGTCGCGCGGCTCGATCTGGAGCTTCTCGATGCACC
GCTTTTGCAAGAGATGCTGGAGAGGATCTGTGCCGCATAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: tetraacyldisaccharide-1-phosphate 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:
NA

Sequences:

>Translated_359_residues
MADLESYFKELMDGKRAGWKDRLALAGLRLASLPYALALRLRALGYAAGLIPSHRLPRPVISVGNVTLGGTGKTPTVAWL
ASYLIGRGKRVAVLSRGYGGSAEGELRIVSDGNNLLVGPEEAGDEPCLLARKVPGLMVVTGADRYRAGLLALKELNPDVF
ILDDGFQHLKLKRDLNLLLLDCRRPFGNDRVLPAGYLREPKSAIGRADLVLFTRCQPESAPQLANLATPACRSLHRLNGC
APLKGGEPLAFSDLKGERCMAFAGIADPAGFFDSLEKEGVQLVTTLAFSDHICYGDAEIAAVLRLKKASRSAFMVTTEKD
AVKLAPFMDQLGTVYVARLDLELLDAPLLQEMLERICAA
>Mature_358_residues
ADLESYFKELMDGKRAGWKDRLALAGLRLASLPYALALRLRALGYAAGLIPSHRLPRPVISVGNVTLGGTGKTPTVAWLA
SYLIGRGKRVAVLSRGYGGSAEGELRIVSDGNNLLVGPEEAGDEPCLLARKVPGLMVVTGADRYRAGLLALKELNPDVFI
LDDGFQHLKLKRDLNLLLLDCRRPFGNDRVLPAGYLREPKSAIGRADLVLFTRCQPESAPQLANLATPACRSLHRLNGCA
PLKGGEPLAFSDLKGERCMAFAGIADPAGFFDSLEKEGVQLVTTLAFSDHICYGDAEIAAVLRLKKASRSAFMVTTEKDA
VKLAPFMDQLGTVYVARLDLELLDAPLLQEMLERICAA

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family [H]

Homologues:

Organism=Escherichia coli, GI1787144, Length=324, Percent_Identity=32.7160493827161, Blast_Score=141, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758 [H]

Pfam domain/function: PF02606 LpxK [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 38756; Mature: 38624

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLESYFKELMDGKRAGWKDRLALAGLRLASLPYALALRLRALGYAAGLIPSHRLPRPV
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ISVGNVTLGGTGKTPTVAWLASYLIGRGKRVAVLSRGYGGSAEGELRIVSDGNNLLVGPE
EEECCEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCEEEECCC
EAGDEPCLLARKVPGLMVVTGADRYRAGLLALKELNPDVFILDDGFQHLKLKRDLNLLLL
CCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCEEEE
DCRRPFGNDRVLPAGYLREPKSAIGRADLVLFTRCQPESAPQLANLATPACRSLHRLNGC
ECCCCCCCCCCCCCHHHCCCHHHHCCCEEEEEEECCCCCCCHHHHHCCHHHHHHHHHCCC
APLKGGEPLAFSDLKGERCMAFAGIADPAGFFDSLEKEGVQLVTTLAFSDHICYGDAEIA
CCCCCCCCEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEEHHCCCEEECCHHHH
AVLRLKKASRSAFMVTTEKDAVKLAPFMDQLGTVYVARLDLELLDAPLLQEMLERICAA
HHHHHHHCCCCEEEEEECCCCEEHHHHHHHHCCEEEEEECHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ADLESYFKELMDGKRAGWKDRLALAGLRLASLPYALALRLRALGYAAGLIPSHRLPRPV
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
ISVGNVTLGGTGKTPTVAWLASYLIGRGKRVAVLSRGYGGSAEGELRIVSDGNNLLVGPE
EEECCEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCEEEECCC
EAGDEPCLLARKVPGLMVVTGADRYRAGLLALKELNPDVFILDDGFQHLKLKRDLNLLLL
CCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCEEEE
DCRRPFGNDRVLPAGYLREPKSAIGRADLVLFTRCQPESAPQLANLATPACRSLHRLNGC
ECCCCCCCCCCCCCHHHCCCHHHHCCCEEEEEEECCCCCCCHHHHHCCHHHHHHHHHCCC
APLKGGEPLAFSDLKGERCMAFAGIADPAGFFDSLEKEGVQLVTTLAFSDHICYGDAEIA
CCCCCCCCEEECCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEEHHCCCEEECCHHHH
AVLRLKKASRSAFMVTTEKDAVKLAPFMDQLGTVYVARLDLELLDAPLLQEMLERICAA
HHHHHHHCCCCEEEEEECCCCEEHHHHHHHHCCEEEEEECHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA