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The map label for this gene is rprX [H]

Identifier: 197119995

GI number: 197119995

Start: 4157354

End: 4158493

Strand: Direct

Name: rprX [H]

Synonym: Gbem_3634

Alternate gene names: 197119995

Gene position: 4157354-4158493 (Clockwise)

Preceding gene: 197119994

Following gene: 197119996

Centisome position: 90.08

GC content: 60.0

Gene sequence:

>1140_bases
ATGCTGCAACTGACCCCAAACCCGAACCAGTCCCTCCAGTTGGAGATCGAGAAGAAAACCGTGCTTATCGTCGACGACGA
GGCGGTGATCCGCGACCTCTGCAAACGGGTGCTGCACGACTACGACGTCATCGAGGCGGGGGACGGGGCAGAGGCGCTGG
AGATCTTCCACAAGGGGGGGGTCGACGTCATCCTCACCGACGTGATGATGCCGGAAATGGACGGGCTTGAGCTCCTGAAA
AACCTGAAGGAGCGGGAGCCGACCGTGGTGGTCATCATCATGACCGGCTTCGCCGACAAGGAACTGATCCTGAAGGCGCT
CAAGGCGGATGCGGACGACTTCATCACCAAGCCGCTCAACCTGCTGCAGCTAAAGAGCGCGGTCGACAAGGCGCTGGTGA
AAAAGGCCCTCAAGGAAGAGATCGCGAACCTGAAGAGCGTCGACAGCTTCAAGACGCTCTTTCTCTCCATGATCTCGCAC
AAGTTCCGCACCCCCATCACCTCCATCTCGCTCTTCCTGCAAAACCTCGCCTCCGGCGTGATAGACACGCGCGACGAAGG
GGCCAGAGAGCACATTGGCCTCGTGTACGACGAGGCGTGCTACCTGGGCAACCTGGTGAGCGAACTCCTCGCCTTTTCCT
CGTTCATGAACGGCAACAGCGATCTGCACTTGGAGCCGTGCGACCTGAAGGATCTCATCCCCTCGCTCATCAGTGACTCG
AAGGAGTGGCTGACGAAACCAGGGGTCGCCCCGCAGAGCGACCTGGAAGAGGTACCCGAGCTGAGGCTCGACCGCGAGAA
GATCGCCTTCGCGCTGCAGCAGGTGATCGACAACGCCATAAAGTTCTCCAAGGATACCGGACTTGTCTGCGTCACCATGA
GAAACCGCGCCGGCAGTTGCCAGATCTCGGTGGAAGACAACGGCATCGGCATACCCAAGGAGCAGTTGCCCAAGATCTTC
GAGAAGTTCTACCAGGTGGACGCCGATCGGACCGGGCAGGTCCGCGGCTTCGGCCTCGGCCTTTTCTACGCCCGCCTGTT
CATCAGGATGCACGGCGGCAGCATCAGCATCGAAAGCGAGCTGAATGTCGGCACCCGCGTCCTCATCAGCATCCCCCACA
CTACCAGTCAAAGCCCCTGA

Upstream 100 bases:

>100_bases
AGGGGGAGGGTTAGGGAGGGGGAAGCGCTGCGGCCCTTTCGACCAAAGCAAACGCAGGCGACCGCCAGTTACAAAAACAA
GATCATCCCGGGACATGCCG

Downstream 100 bases:

>100_bases
TAGATCGTAGCATCGGCCTTTCAGTCAAACCCTCTTTGAAGTTGATTATTTCCCTCTATCTGCTATATTAACGTCTTTCA
AAACGGCCATAAACTATGAA

Product: response receiver histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MLQLTPNPNQSLQLEIEKKTVLIVDDEAVIRDLCKRVLHDYDVIEAGDGAEALEIFHKGGVDVILTDVMMPEMDGLELLK
NLKEREPTVVVIIMTGFADKELILKALKADADDFITKPLNLLQLKSAVDKALVKKALKEEIANLKSVDSFKTLFLSMISH
KFRTPITSISLFLQNLASGVIDTRDEGAREHIGLVYDEACYLGNLVSELLAFSSFMNGNSDLHLEPCDLKDLIPSLISDS
KEWLTKPGVAPQSDLEEVPELRLDREKIAFALQQVIDNAIKFSKDTGLVCVTMRNRAGSCQISVEDNGIGIPKEQLPKIF
EKFYQVDADRTGQVRGFGLGLFYARLFIRMHGGSISIESELNVGTRVLISIPHTTSQSP

Sequences:

>Translated_379_residues
MLQLTPNPNQSLQLEIEKKTVLIVDDEAVIRDLCKRVLHDYDVIEAGDGAEALEIFHKGGVDVILTDVMMPEMDGLELLK
NLKEREPTVVVIIMTGFADKELILKALKADADDFITKPLNLLQLKSAVDKALVKKALKEEIANLKSVDSFKTLFLSMISH
KFRTPITSISLFLQNLASGVIDTRDEGAREHIGLVYDEACYLGNLVSELLAFSSFMNGNSDLHLEPCDLKDLIPSLISDS
KEWLTKPGVAPQSDLEEVPELRLDREKIAFALQQVIDNAIKFSKDTGLVCVTMRNRAGSCQISVEDNGIGIPKEQLPKIF
EKFYQVDADRTGQVRGFGLGLFYARLFIRMHGGSISIESELNVGTRVLISIPHTTSQSP
>Mature_379_residues
MLQLTPNPNQSLQLEIEKKTVLIVDDEAVIRDLCKRVLHDYDVIEAGDGAEALEIFHKGGVDVILTDVMMPEMDGLELLK
NLKEREPTVVVIIMTGFADKELILKALKADADDFITKPLNLLQLKSAVDKALVKKALKEEIANLKSVDSFKTLFLSMISH
KFRTPITSISLFLQNLASGVIDTRDEGAREHIGLVYDEACYLGNLVSELLAFSSFMNGNSDLHLEPCDLKDLIPSLISDS
KEWLTKPGVAPQSDLEEVPELRLDREKIAFALQQVIDNAIKFSKDTGLVCVTMRNRAGSCQISVEDNGIGIPKEQLPKIF
EKFYQVDADRTGQVRGFGLGLFYARLFIRMHGGSISIESELNVGTRVLISIPHTTSQSP

Specific function: Member of the two-component regulatory system rprX/rprY. May activate rprY by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=30.4347826086957, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=25.6916996047431, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=37.3015873015873, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=27.8884462151394, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786600, Length=271, Percent_Identity=24.3542435424354, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790299, Length=132, Percent_Identity=32.5757575757576, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=36.8421052631579, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=25.6521739130435, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=26.5765765765766, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=217, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=25.3012048192771, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=21.978021978022, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081816, Length=246, Percent_Identity=24.7967479674797, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790863, Length=137, Percent_Identity=32.1167883211679, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786783, Length=102, Percent_Identity=30.3921568627451, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788191, Length=118, Percent_Identity=33.8983050847458, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=24.8979591836735, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788905, Length=96, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1789808, Length=250, Percent_Identity=24.4, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1786599, Length=121, Percent_Identity=31.404958677686, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1787229, Length=116, Percent_Identity=35.3448275862069, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=23.9495798319328, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42053; Mature: 42053

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLTPNPNQSLQLEIEKKTVLIVDDEAVIRDLCKRVLHDYDVIEAGDGAEALEIFHKGG
CCCCCCCCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHCCC
VDVILTDVMMPEMDGLELLKNLKEREPTVVVIIMTGFADKELILKALKADADDFITKPLN
CCEEEHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCHHHHHHCCHH
LLQLKSAVDKALVKKALKEEIANLKSVDSFKTLFLSMISHKFRTPITSISLFLQNLASGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
IDTRDEGAREHIGLVYDEACYLGNLVSELLAFSSFMNGNSDLHLEPCDLKDLIPSLISDS
CCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHCCC
KEWLTKPGVAPQSDLEEVPELRLDREKIAFALQQVIDNAIKFSKDTGLVCVTMRNRAGSC
HHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCE
QISVEDNGIGIPKEQLPKIFEKFYQVDADRTGQVRGFGLGLFYARLFIRMHGGSISIESE
EEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEECC
LNVGTRVLISIPHTTSQSP
CCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MLQLTPNPNQSLQLEIEKKTVLIVDDEAVIRDLCKRVLHDYDVIEAGDGAEALEIFHKGG
CCCCCCCCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHCCC
VDVILTDVMMPEMDGLELLKNLKEREPTVVVIIMTGFADKELILKALKADADDFITKPLN
CCEEEHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCHHHHHHCCHH
LLQLKSAVDKALVKKALKEEIANLKSVDSFKTLFLSMISHKFRTPITSISLFLQNLASGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
IDTRDEGAREHIGLVYDEACYLGNLVSELLAFSSFMNGNSDLHLEPCDLKDLIPSLISDS
CCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHCCC
KEWLTKPGVAPQSDLEEVPELRLDREKIAFALQQVIDNAIKFSKDTGLVCVTMRNRAGSC
HHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCE
QISVEDNGIGIPKEQLPKIFEKFYQVDADRTGQVRGFGLGLFYARLFIRMHGGSISIESE
EEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEECC
LNVGTRVLISIPHTTSQSP
CCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8469117 [H]