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The map label for this gene is argB

Identifier: 197119996

GI number: 197119996

Start: 4158604

End: 4159482

Strand: Direct

Name: argB

Synonym: Gbem_3635

Alternate gene names: 197119996

Gene position: 4158604-4159482 (Clockwise)

Preceding gene: 197119995

Following gene: 197119997

Centisome position: 90.11

GC content: 59.5

Gene sequence:

>879_bases
ATGCAGCAACTCATAGAAAAGGCGAGCACACTCATGGAGGCGCTCCCTTATATCAGACGTTTTTCCGGCAAGACTATCGT
CATCAAGTACGGCGGCCACGCGATGGCTGATGAGAAGCTCAGGAAGTCTTTCGCACTCGACGTCATCCTGCTCAAATACA
TTGGCATCAATACCGTGGTAGTACACGGCGGCGGTCCGCAGATAAACGAGACACTGAAGCGCTACGGCATAGTGTCAGAG
TTCGTGAAGGGGATGCGCGTCACCGATAAAGAGACGATGGGCGTCGTGGAGATGGTCCTGACCGGGCAGGTCAACCGCGA
GGTGGTGGGATACATCAACCAGAACGGCGGCCGCGCGGCCGGACTCTCCGGCAAAGACGGCGACCTCTTGATCTGCGAGA
AGCTGCTGCAGGAAGTAAAGAGCGAAGACGGCAGCACCGAGACGGTCGACATCGGTTTCGTCGGCGACGTAGTCGAGGTG
AACCCCGCCATATTACAGGCATTGGAAAAGGGGGGCTTCATACCGGTCATAGCGCCGGTAGGAGTAGGTCGAGCCGGGGA
GAGCTACAACATCAACGCCGACGTCGTGGCCGGCAAGGTCGCGGCCGCCCTTAACGCCGAAAAACTGATCCTTTTGACCG
ACGTCTCGGGAGTGAAGAGCAAGGAGGGGGAACTCCTCTCCAGCATCCCGCTCGCCGATGTCCCCGCCCTCATCGACAAC
GGCACCGTCACCGGCGGGATGATCCCCAAGGTCACCTGCTGCACCGACGCGCTTGCCGCCGGGGTCAAGAAGGCCCACAT
CGTGGACGGCCGGATCGAGCACGCGATCCTGCTGGAGATCTTCACCAACGTCGGGATCGGGACGGAAATACAGGCTTAA

Upstream 100 bases:

>100_bases
CATCGGCCTTTCAGTCAAACCCTCTTTGAAGTTGATTATTTCCCTCTATCTGCTATATTAACGTCTTTCAAAACGGCCAT
AAACTATGAAAGAGGCGCCA

Downstream 100 bases:

>100_bases
CTGCCAACTGCCGTTCAACGTTCAATGTTCGACAAAATTCGAGCCAGTAGAAGCCTCACCGTACGGCGCCGTCACAGTGA
GAAGGACAACTAGCCCACGC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MQQLIEKASTLMEALPYIRRFSGKTIVIKYGGHAMADEKLRKSFALDVILLKYIGINTVVVHGGGPQINETLKRYGIVSE
FVKGMRVTDKETMGVVEMVLTGQVNREVVGYINQNGGRAAGLSGKDGDLLICEKLLQEVKSEDGSTETVDIGFVGDVVEV
NPAILQALEKGGFIPVIAPVGVGRAGESYNINADVVAGKVAAALNAEKLILLTDVSGVKSKEGELLSSIPLADVPALIDN
GTVTGGMIPKVTCCTDALAAGVKKAHIVDGRIEHAILLEIFTNVGIGTEIQA

Sequences:

>Translated_292_residues
MQQLIEKASTLMEALPYIRRFSGKTIVIKYGGHAMADEKLRKSFALDVILLKYIGINTVVVHGGGPQINETLKRYGIVSE
FVKGMRVTDKETMGVVEMVLTGQVNREVVGYINQNGGRAAGLSGKDGDLLICEKLLQEVKSEDGSTETVDIGFVGDVVEV
NPAILQALEKGGFIPVIAPVGVGRAGESYNINADVVAGKVAAALNAEKLILLTDVSGVKSKEGELLSSIPLADVPALIDN
GTVTGGMIPKVTCCTDALAAGVKKAHIVDGRIEHAILLEIFTNVGIGTEIQA
>Mature_292_residues
MQQLIEKASTLMEALPYIRRFSGKTIVIKYGGHAMADEKLRKSFALDVILLKYIGINTVVVHGGGPQINETLKRYGIVSE
FVKGMRVTDKETMGVVEMVLTGQVNREVVGYINQNGGRAAGLSGKDGDLLICEKLLQEVKSEDGSTETVDIGFVGDVVEV
NPAILQALEKGGFIPVIAPVGVGRAGESYNINADVVAGKVAAALNAEKLILLTDVSGVKSKEGELLSSIPLADVPALIDN
GTVTGGMIPKVTCCTDALAAGVKKAHIVDGRIEHAILLEIFTNVGIGTEIQA

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=297, Percent_Identity=28.956228956229, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI145693208, Length=269, Percent_Identity=30.4832713754647, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320913, Length=297, Percent_Identity=26.9360269360269, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_GEOBB (B5ED10)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002140423.1
- ProteinModelPortal:   B5ED10
- SMR:   B5ED10
- GeneID:   6780499
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_3635
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 30810; Mature: 30810

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: BINDING 86-86 BINDING 190-190

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLIEKASTLMEALPYIRRFSGKTIVIKYGGHAMADEKLRKSFALDVILLKYIGINTVV
CHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
VHGGGPQINETLKRYGIVSEFVKGMRVTDKETMGVVEMVLTGQVNREVVGYINQNGGRAA
EECCCCCHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEC
GLSGKDGDLLICEKLLQEVKSEDGSTETVDIGFVGDVVEVNPAILQALEKGGFIPVIAPV
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCEECCHHHHHHHHHCCCEEEEECC
GVGRAGESYNINADVVAGKVAAALNAEKLILLTDVSGVKSKEGELLSSIPLADVPALIDN
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHCCCCHHCCHHHCC
GTVTGGMIPKVTCCTDALAAGVKKAHIVDGRIEHAILLEIFTNVGIGTEIQA
CEECCCCCCCHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQQLIEKASTLMEALPYIRRFSGKTIVIKYGGHAMADEKLRKSFALDVILLKYIGINTVV
CHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
VHGGGPQINETLKRYGIVSEFVKGMRVTDKETMGVVEMVLTGQVNREVVGYINQNGGRAA
EECCCCCHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEC
GLSGKDGDLLICEKLLQEVKSEDGSTETVDIGFVGDVVEVNPAILQALEKGGFIPVIAPV
CCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCEECCHHHHHHHHHCCCEEEEECC
GVGRAGESYNINADVVAGKVAAALNAEKLILLTDVSGVKSKEGELLSSIPLADVPALIDN
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHCCCCHHCCHHHCC
GTVTGGMIPKVTCCTDALAAGVKKAHIVDGRIEHAILLEIFTNVGIGTEIQA
CEECCCCCCCHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA