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The map label for this gene is cinA [C]

Identifier: 197119989

GI number: 197119989

Start: 4148210

End: 4149454

Strand: Direct

Name: cinA [C]

Synonym: Gbem_3628

Alternate gene names: 197119989

Gene position: 4148210-4149454 (Clockwise)

Preceding gene: 197119988

Following gene: 197119990

Centisome position: 89.88

GC content: 68.51

Gene sequence:

>1245_bases
ATGAGGGTGGCGGTTCTTTCCATAGGGGACGAGCTTCTCTCCGGCGAGGTGGTGGACACCAACGCAAGCCACATCGCCGA
CCGGCTCTTCCAGGCGGGGGGGCGGGTAGAGCGGCACCTGACCGTCCCCGACGACGCGGAGGCGATCGCCTCCGCCCTCA
CGGAGCTCGGCGCGCGCAGCGACGCGGTTATAGTCACCGGGGGCTTGGGCCCCACCCCGGACGACTTGACCGCCGAGGCC
GCGGCGCGGGCAGCCGGAACGGAACTGGAGCTCTCATCTGAAGCGCTTGACCACCTGGAGCGCTTCGCCCAGAGGATCAC
CGGAGAGCTGCACCCGGCCAACCGCAGGCAGGCGCTTCTCCCCAAAGGGTGCAGGCTGATCCCCAACCCTTTGGGAACCG
CCTTGGGCTTCGTGGTCCGCATAGGTCAGGCCGACTGCTTCTTCATGCCCGGCGTCCCCTACGAGATGGAGCGGATGCTG
GAAGAGACGGTGCTCCCGGAGCTTACCGGCAGGTTCGAAGCCGGCTGGCAGCGGGTGACGCTGAAGCTTTTCGGCATCGC
CGAGGCTGCCATCGCGGAACTTCTGGAGGGGGCGATTCCCGAAGGGTCCCCGGTGCAGCTTGCCTACTGCGTGAAGTTCC
CGGAGATCCACCTGATCCTGCGGGCCACGGCCAGCGACGCGCCCTTCTTGCAGCAGGCGGCCGGCGAGCTGCGGCAGCGC
CTTTCCGCCTATCTCTTTGCCGAGGACCGGGAGGAGATGGACGACCGGCTGGCGCTTTTGCTGCGGGAAAGCGGTCTCAC
CCTGGCGCTGGCCGAATCCTGCACCGGCGGCATGATCGCCGCCCGCATCACCGCCGTCGCGGGAAGCTCCGCCTATTTCC
TGGAAGGAAACGTCACCTACAGCAACGAGGCGAAGACCAGGATGCTGCAGGTCCCCGCCCCCCTGATAGCGGAGCACGGC
GCGGTCAGCGCCGAGGTCGCCCGCGCCATGGCGGTCGGGGCGAGGGAGGCGGCGGGAAGCGACCTGGCGTTGTCGGTGAC
CGGCATCGCCGGCCCGGACGGGGGGACCCCCGAAAAGCCGGTCGGCACCGTCTACCTGGCCCTTGTCGACCAAGGCTCTT
GCCGGGTCGAGCGCTTCAACTTCCAGGGCGACCGCGACCGCGTCCGTTCCATCACCTGCTTCACCGCGCTCGATTGGCTG
CGCCGCTACCTCCTCACACGGAAGACGACACCAGGCCGGGGTTGA

Upstream 100 bases:

>100_bases
GGTTCGACCGGTCGCTCAAAAACGGCTACGGGGTGGTGCTCGACGACGTCATGGCGGGGCTCTACGCCTGCGCGACGACG
CACCTGGCCCTGAGGTTCCT

Downstream 100 bases:

>100_bases
CCGGTCACAACAAGTTGCCGGTACAGAGGACACGTTCTTGCACTTCGCACCGTTCCTGCTCATAGCCGTTTGCGAGCTGA
TATTGCTCTTCATCGGGAGG

Product: competence/damage-inducible protein CinA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MRVAVLSIGDELLSGEVVDTNASHIADRLFQAGGRVERHLTVPDDAEAIASALTELGARSDAVIVTGGLGPTPDDLTAEA
AARAAGTELELSSEALDHLERFAQRITGELHPANRRQALLPKGCRLIPNPLGTALGFVVRIGQADCFFMPGVPYEMERML
EETVLPELTGRFEAGWQRVTLKLFGIAEAAIAELLEGAIPEGSPVQLAYCVKFPEIHLILRATASDAPFLQQAAGELRQR
LSAYLFAEDREEMDDRLALLLRESGLTLALAESCTGGMIAARITAVAGSSAYFLEGNVTYSNEAKTRMLQVPAPLIAEHG
AVSAEVARAMAVGAREAAGSDLALSVTGIAGPDGGTPEKPVGTVYLALVDQGSCRVERFNFQGDRDRVRSITCFTALDWL
RRYLLTRKTTPGRG

Sequences:

>Translated_414_residues
MRVAVLSIGDELLSGEVVDTNASHIADRLFQAGGRVERHLTVPDDAEAIASALTELGARSDAVIVTGGLGPTPDDLTAEA
AARAAGTELELSSEALDHLERFAQRITGELHPANRRQALLPKGCRLIPNPLGTALGFVVRIGQADCFFMPGVPYEMERML
EETVLPELTGRFEAGWQRVTLKLFGIAEAAIAELLEGAIPEGSPVQLAYCVKFPEIHLILRATASDAPFLQQAAGELRQR
LSAYLFAEDREEMDDRLALLLRESGLTLALAESCTGGMIAARITAVAGSSAYFLEGNVTYSNEAKTRMLQVPAPLIAEHG
AVSAEVARAMAVGAREAAGSDLALSVTGIAGPDGGTPEKPVGTVYLALVDQGSCRVERFNFQGDRDRVRSITCFTALDWL
RRYLLTRKTTPGRG
>Mature_414_residues
MRVAVLSIGDELLSGEVVDTNASHIADRLFQAGGRVERHLTVPDDAEAIASALTELGARSDAVIVTGGLGPTPDDLTAEA
AARAAGTELELSSEALDHLERFAQRITGELHPANRRQALLPKGCRLIPNPLGTALGFVVRIGQADCFFMPGVPYEMERML
EETVLPELTGRFEAGWQRVTLKLFGIAEAAIAELLEGAIPEGSPVQLAYCVKFPEIHLILRATASDAPFLQQAAGELRQR
LSAYLFAEDREEMDDRLALLLRESGLTLALAESCTGGMIAARITAVAGSSAYFLEGNVTYSNEAKTRMLQVPAPLIAEHG
AVSAEVARAMAVGAREAAGSDLALSVTGIAGPDGGTPEKPVGTVYLALVDQGSCRVERFNFQGDRDRVRSITCFTALDWL
RRYLLTRKTTPGRG

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Homo sapiens, GI296434309, Length=160, Percent_Identity=32.5, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI41872403, Length=160, Percent_Identity=32.5, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI41872389, Length=160, Percent_Identity=32.5, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788583, Length=287, Percent_Identity=36.2369337979094, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1789052, Length=155, Percent_Identity=48.3870967741936, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787818, Length=151, Percent_Identity=33.112582781457, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71993974, Length=176, Percent_Identity=29.5454545454545, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71993966, Length=176, Percent_Identity=29.5454545454545, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323832, Length=161, Percent_Identity=30.4347826086957, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINAL_GEOBB (B5ED03)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002140416.1
- ProteinModelPortal:   B5ED03
- GeneID:   6780492
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_3628
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- ProtClustDB:   CLSK827663
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 44253; Mature: 44253

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAVLSIGDELLSGEVVDTNASHIADRLFQAGGRVERHLTVPDDAEAIASALTELGARS
CEEEEEECCHHHHCCCEECCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCC
DAVIVTGGLGPTPDDLTAEAAARAAGTELELSSEALDHLERFAQRITGELHPANRRQALL
CEEEEECCCCCCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PKGCRLIPNPLGTALGFVVRIGQADCFFMPGVPYEMERMLEETVLPELTGRFEAGWQRVT
CCCCEECCCHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHCHHHCCHHEEE
LKLFGIAEAAIAELLEGAIPEGSPVQLAYCVKFPEIHLILRATASDAPFLQQAAGELRQR
EEEEHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHH
LSAYLFAEDREEMDDRLALLLRESGLTLALAESCTGGMIAARITAVAGSSAYFLEGNVTY
HHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCEEE
SNEAKTRMLQVPAPLIAEHGAVSAEVARAMAVGAREAAGSDLALSVTGIAGPDGGTPEKP
CCCHHHEEEECCCHHHHHCCCHHHHHHHHHHHCCHHCCCCCEEEEEEEECCCCCCCCCCC
VGTVYLALVDQGSCRVERFNFQGDRDRVRSITCFTALDWLRRYLLTRKTTPGRG
CCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRVAVLSIGDELLSGEVVDTNASHIADRLFQAGGRVERHLTVPDDAEAIASALTELGARS
CEEEEEECCHHHHCCCEECCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCC
DAVIVTGGLGPTPDDLTAEAAARAAGTELELSSEALDHLERFAQRITGELHPANRRQALL
CEEEEECCCCCCCCCHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PKGCRLIPNPLGTALGFVVRIGQADCFFMPGVPYEMERMLEETVLPELTGRFEAGWQRVT
CCCCEECCCHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHCHHHCCHHEEE
LKLFGIAEAAIAELLEGAIPEGSPVQLAYCVKFPEIHLILRATASDAPFLQQAAGELRQR
EEEEHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHH
LSAYLFAEDREEMDDRLALLLRESGLTLALAESCTGGMIAARITAVAGSSAYFLEGNVTY
HHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCEEE
SNEAKTRMLQVPAPLIAEHGAVSAEVARAMAVGAREAAGSDLALSVTGIAGPDGGTPEKP
CCCHHHEEEECCCHHHHHCCCHHHHHHHHHHHCCHHCCCCCEEEEEEEECCCCCCCCCCC
VGTVYLALVDQGSCRVERFNFQGDRDRVRSITCFTALDWLRRYLLTRKTTPGRG
CCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA