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The map label for this gene is nadA

Identifier: 197119881

GI number: 197119881

Start: 4028811

End: 4029725

Strand: Direct

Name: nadA

Synonym: Gbem_3519

Alternate gene names: 197119881

Gene position: 4028811-4029725 (Clockwise)

Preceding gene: 197119878

Following gene: 197119882

Centisome position: 87.3

GC content: 59.89

Gene sequence:

>915_bases
ATGACGCAGGAAACTTTAAAAGCAGATATTAAAGCGCTTCTCAAAGAGCGCAATGCTGTACTTCTCGCTCACAACTACAT
GCGTGACGAGGTGCAGGAAATAGCAGACATAACCGGCGACTCGCTGGCGCTTTCCATAGAAGCGGCAAAGACAGATGCGG
AGGTGATCGTATTCTGCGGCGTCCACTTCATGGCCGAATCCGCCTCCATCCTGGCTCCTGAAAAAACGGTTCTCCTCCCC
CGCCTCGACGCGGGATGCCCCATGGCCGACATGGTTTCGGTCGAGGCCCTCAGGGAAATGAAGGCGAAGCTCCCCGGCGT
GCCGGTGGTCACCTACGTGAACTCTTCCGCCGCGGTCAAGGCCGAAAGCGACATCTGCTGCACCTCCGCGAACGCCGTGA
AAGTGGTCCAGTCGATGAGCGAAAAGGAGATAATCTTCGCCCCGGACCGCAACTTGGGGAGCTACATCGCCCGCTTCACC
GACAAGAAGTTCCACCTCTGGGAAGGGTACTGCCCGACCCACGAGCGGCTCAGGCCCGAGGTGGTCAAGGAGCTGAAACA
GGCTAACCCCGACGCCCCCTTCGTCTGCCATCCCGAATGCAACCCCAAGGTGGTCGAACTGGCAGACCATGTCTGCTCCA
CCACCGGGATGTACGACTACTGCAAGAAGAGCGGCGCCAAGCGCTTCATCATCGGCACCGAGGCGGGAATACTGTGGCGG
CTCAAGCGTGAGAACCCGGACAAGGAGTTCATCCTCGCCTCCCCGGCGCTCATCTGCCCCAACATGAAGCTCACCTCCCT
GGAGGACGTCTTCGAGGCGCTGCAGCAGATGAAGCCCGTGGTCAAGGTCCCGGAAGATATCCGCATCCCCGCCAAGCGCG
CACTGGACCGGATGCTCGCCATCCCGAGAGATTAG

Upstream 100 bases:

>100_bases
TCTGCACCCTTAATTGGTTTGACATGAACCTTAACATTGTCTACTATCGGTGCTGTTTACCATATGTATTCCCAATGAAC
TAGTTTTGGCGGTGATGAAT

Downstream 100 bases:

>100_bases
CCGGCAGCCCCAGAGCACCAGACTTCCCATAAACGACAGGAGCCCCATATGATCCGACCGTTCAAGGGTATCGCCCCCAA
GATAGATCCCTCCGCGTTCA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTQETLKADIKALLKERNAVLLAHNYMRDEVQEIADITGDSLALSIEAAKTDAEVIVFCGVHFMAESASILAPEKTVLLP
RLDAGCPMADMVSVEALREMKAKLPGVPVVTYVNSSAAVKAESDICCTSANAVKVVQSMSEKEIIFAPDRNLGSYIARFT
DKKFHLWEGYCPTHERLRPEVVKELKQANPDAPFVCHPECNPKVVELADHVCSTTGMYDYCKKSGAKRFIIGTEAGILWR
LKRENPDKEFILASPALICPNMKLTSLEDVFEALQQMKPVVKVPEDIRIPAKRALDRMLAIPRD

Sequences:

>Translated_304_residues
MTQETLKADIKALLKERNAVLLAHNYMRDEVQEIADITGDSLALSIEAAKTDAEVIVFCGVHFMAESASILAPEKTVLLP
RLDAGCPMADMVSVEALREMKAKLPGVPVVTYVNSSAAVKAESDICCTSANAVKVVQSMSEKEIIFAPDRNLGSYIARFT
DKKFHLWEGYCPTHERLRPEVVKELKQANPDAPFVCHPECNPKVVELADHVCSTTGMYDYCKKSGAKRFIIGTEAGILWR
LKRENPDKEFILASPALICPNMKLTSLEDVFEALQQMKPVVKVPEDIRIPAKRALDRMLAIPRD
>Mature_303_residues
TQETLKADIKALLKERNAVLLAHNYMRDEVQEIADITGDSLALSIEAAKTDAEVIVFCGVHFMAESASILAPEKTVLLPR
LDAGCPMADMVSVEALREMKAKLPGVPVVTYVNSSAAVKAESDICCTSANAVKVVQSMSEKEIIFAPDRNLGSYIARFTD
KKFHLWEGYCPTHERLRPEVVKELKQANPDAPFVCHPECNPKVVELADHVCSTTGMYDYCKKSGAKRFIIGTEAGILWRL
KRENPDKEFILASPALICPNMKLTSLEDVFEALQQMKPVVKVPEDIRIPAKRALDRMLAIPRD

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=308, Percent_Identity=37.987012987013, Blast_Score=188, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_GEOBB (B5EC56)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002140308.1
- GeneID:   6780382
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_3519
- HOGENOM:   HBG291157
- OMA:   CHPECNP
- ProtClustDB:   PRK09375
- GO:   GO:0005737
- HAMAP:   MF_00568
- InterPro:   IPR003473
- InterPro:   IPR023066
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 33716; Mature: 33584

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: BINDING 24-24 BINDING 41-41 BINDING 112-112 BINDING 129-129 BINDING 197-197 BINDING 214-214

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQETLKADIKALLKERNAVLLAHNYMRDEVQEIADITGDSLALSIEAAKTDAEVIVFCG
CCHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEC
VHFMAESASILAPEKTVLLPRLDAGCPMADMVSVEALREMKAKLPGVPVVTYVNSSAAVK
HHHHHCCCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEE
AESDICCTSANAVKVVQSMSEKEIIFAPDRNLGSYIARFTDKKFHLWEGYCPTHERLRPE
ECCCCEECCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCCCEEEECCCCCCHHHCCHH
VVKELKQANPDAPFVCHPECNPKVVELADHVCSTTGMYDYCKKSGAKRFIIGTEAGILWR
HHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCEEEE
LKRENPDKEFILASPALICPNMKLTSLEDVFEALQQMKPVVKVPEDIRIPAKRALDRMLA
EECCCCCCCEEEECCCEECCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHC
IPRD
CCCC
>Mature Secondary Structure 
TQETLKADIKALLKERNAVLLAHNYMRDEVQEIADITGDSLALSIEAAKTDAEVIVFCG
CHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEC
VHFMAESASILAPEKTVLLPRLDAGCPMADMVSVEALREMKAKLPGVPVVTYVNSSAAVK
HHHHHCCCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEE
AESDICCTSANAVKVVQSMSEKEIIFAPDRNLGSYIARFTDKKFHLWEGYCPTHERLRPE
ECCCCEECCCHHHHHHHHCCCCCEEECCCCCHHHHHHHHCCCCEEEECCCCCCHHHCCHH
VVKELKQANPDAPFVCHPECNPKVVELADHVCSTTGMYDYCKKSGAKRFIIGTEAGILWR
HHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCCCEEEE
LKRENPDKEFILASPALICPNMKLTSLEDVFEALQQMKPVVKVPEDIRIPAKRALDRMLA
EECCCCCCCEEEECCCEECCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHC
IPRD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA