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The map label for this gene is hda [H]

Identifier: 197119682

GI number: 197119682

Start: 3813583

End: 3814287

Strand: Direct

Name: hda [H]

Synonym: Gbem_3317

Alternate gene names: 197119682

Gene position: 3813583-3814287 (Clockwise)

Preceding gene: 197119681

Following gene: 197119687

Centisome position: 82.63

GC content: 60.43

Gene sequence:

>705_bases
ATGCAGCTTATCTTTGATTTCCCGGTGGTGCCGCGTTTCGGCTTTGAGAACTTCGTGGTCTGCGGCGGCAACAAGACTGC
CTACCAGTTCGCGAAGAAGCTGGTCGAGGACCCGACGGAGAACCTTCTCTACATCTACGGCCCGGAAGGCTCGGGCAAAA
CCCACCTTTTGACCGCCCTCTCCAATTCCATCGACGGCAGGTACTTTTCCTTCCGGGACGCAGGCTCGCTATACGGCTCC
AGCGTCGGCAGCGAAGGCCCTTCCCGGCTGGCCGAGCACTTCCAGGGCGCGGCCGCGCTGGTACTGGACGACCTGCATCT
CCTCCCCAACCTGCACGAAGTGCGGGTCGAGCTTTGGGAACTCTTCAACGCCTTTTACAGTTCCGGCCGCAAAATCGCCA
TCTCCGGCCTTATGCCCCCCAAAGAGCTGCCGCACCTGGACGGGCACCTGACCAGCCGCCTGCTCTGGGGCCTTGTGGCG
CGGATGGACGTCTCCGACGACGAGTCCAGGAGGATGATCCTGAAGAAGCTGGCCGAGGACCGACAGATGGCGCTTCCTGA
CGACGTCATAGACGAGATGCTCTTGAGGGTGAGGCGGGACATTCCGTCGCTCGTGTACGCCCTGGAGAACATCAACCGCT
ACGCCATCTCGACCAAGAGAAAGGTGAGCCTTAGGCTGGCGAAAGAAGCTTTTAGAGGCAATTGA

Upstream 100 bases:

>100_bases
CTACTTCATTGCAGAAATACTGGCACAGCACTTGACCTGACAGCGGGTTCGCTTTTCGTTGTCAATTGTCAATTGTCAAT
TGTCAATTGGTGTTAGCCTT

Downstream 100 bases:

>100_bases
GAAGCAATTCAGAGTCAATTGACAATTGACAATTGACAATGCAACCCTTACTCACTACTGCGGCAGCACCAATACAAAAA
AGGCTTCTGAACTTCCTCTA

Product: DnaA regulatory inactivator Hda

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MQLIFDFPVVPRFGFENFVVCGGNKTAYQFAKKLVEDPTENLLYIYGPEGSGKTHLLTALSNSIDGRYFSFRDAGSLYGS
SVGSEGPSRLAEHFQGAAALVLDDLHLLPNLHEVRVELWELFNAFYSSGRKIAISGLMPPKELPHLDGHLTSRLLWGLVA
RMDVSDDESRRMILKKLAEDRQMALPDDVIDEMLLRVRRDIPSLVYALENINRYAISTKRKVSLRLAKEAFRGN

Sequences:

>Translated_234_residues
MQLIFDFPVVPRFGFENFVVCGGNKTAYQFAKKLVEDPTENLLYIYGPEGSGKTHLLTALSNSIDGRYFSFRDAGSLYGS
SVGSEGPSRLAEHFQGAAALVLDDLHLLPNLHEVRVELWELFNAFYSSGRKIAISGLMPPKELPHLDGHLTSRLLWGLVA
RMDVSDDESRRMILKKLAEDRQMALPDDVIDEMLLRVRRDIPSLVYALENINRYAISTKRKVSLRLAKEAFRGN
>Mature_234_residues
MQLIFDFPVVPRFGFENFVVCGGNKTAYQFAKKLVEDPTENLLYIYGPEGSGKTHLLTALSNSIDGRYFSFRDAGSLYGS
SVGSEGPSRLAEHFQGAAALVLDDLHLLPNLHEVRVELWELFNAFYSSGRKIAISGLMPPKELPHLDGHLTSRLLWGLVA
RMDVSDDESRRMILKKLAEDRQMALPDDVIDEMLLRVRRDIPSLVYALENINRYAISTKRKVSLRLAKEAFRGN

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=233, Percent_Identity=27.8969957081545, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI226510964, Length=215, Percent_Identity=24.1860465116279, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 26373; Mature: 26373

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLIFDFPVVPRFGFENFVVCGGNKTAYQFAKKLVEDPTENLLYIYGPEGSGKTHLLTAL
CCEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHH
SNSIDGRYFSFRDAGSLYGSSVGSEGPSRLAEHFQGAAALVLDDLHLLPNLHEVRVELWE
HHCCCCCEEEECCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHH
LFNAFYSSGRKIAISGLMPPKELPHLDGHLTSRLLWGLVARMDVSDDESRRMILKKLAED
HHHHHHHCCCEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RQMALPDDVIDEMLLRVRRDIPSLVYALENINRYAISTKRKVSLRLAKEAFRGN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLIFDFPVVPRFGFENFVVCGGNKTAYQFAKKLVEDPTENLLYIYGPEGSGKTHLLTAL
CCEEECCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHH
SNSIDGRYFSFRDAGSLYGSSVGSEGPSRLAEHFQGAAALVLDDLHLLPNLHEVRVELWE
HHCCCCCEEEECCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHH
LFNAFYSSGRKIAISGLMPPKELPHLDGHLTSRLLWGLVARMDVSDDESRRMILKKLAED
HHHHHHHCCCEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RQMALPDDVIDEMLLRVRRDIPSLVYALENINRYAISTKRKVSLRLAKEAFRGN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA