Click here to switch to the map view.

The map label for this gene is argE [H]

Identifier: 197119548

GI number: 197119548

Start: 3665071

End: 3666282

Strand: Direct

Name: argE [H]

Synonym: Gbem_3178

Alternate gene names: 197119548

Gene position: 3665071-3666282 (Clockwise)

Preceding gene: 197119547

Following gene: 197119549

Centisome position: 79.41

GC content: 64.19

Gene sequence:

>1212_bases
ATGACCGGGCGCCTGGAGGAGGTTTTCGCCGCCATCGATCCGGCACGTCTCAAGGGAACCCTGCTGGAGATGCTGGACAT
ATATTCCCCCTCGGGGAAGGAGGAGGACATCCAGCTCTACCTCGAGGACCTGCTCGCTGGCGCCGGGTTCTACGTCGAGC
GGCAGGAGGTGGAGGAGGAGCGCTACAACCTGCGGGTGACCATGGGGGAAGGCGAGCCTGAGCTTTACCTCGTGGGGCAC
GTGGACACGGTTCCGGCGTGGGACCTGGAGGAATTCGGCGCCAGGGTGGAAGGCGACGCCATCGGAGGGCTGGGGAGCGC
CGACATGAAGGGGGGGTGCGCCGCCATGATCGAGGCGTGGCTCGCCATGGCCCAGGCCTTGAAACCGGGCCGGCGCCCGA
ACGTGGGGCTTTTGCTTGTGGTGGGGGAGGAGGAGAACGGCGACGGCAGCGCCAGTTTCCTGAAAAACTGCAGTCCCGCC
TGGGCGGTGATCGGGGAGCCTACCGGCCTCTCAGCCTGCTTCGCCCACTACGGCTACCTGGAGGCCGGCTTCGTCACCCA
CGGGTTGAGGAGCCACTCCTCCTTGCCGGAATTGGGGCACAACGCGGTGGAATCGATGCTGAGGGTGCTTTTGCACTTAA
GCAAGGACCCGCTGTTCCACCGGGAGCAAGGGAGCATCGTCTACTCCATCAGGGAGATGCACTCCTCCCAGAAGGGGTTC
GTGGTCCCGGACCGGTGCGAATCCTGGATCGACCTGCATCTTCCCCCAGAGCTCGACCCGGAGTCCGTGCAGCGGGGAAT
TAGCCATATCGTCTCCAGCGCAGGTCAATACATACCCGGTCTAGACTTAAACGTCGCCTTCAATTTCGCCTCGGCCGGCT
ACAACCTCGGTACCGACAACCCACTTTCCTGCATCCTGGAACAGGTCTACCAGCGCCTTGGGCGCACCCTCAAATTCGAT
TCCTTCCGCTCGCACTCCGACGGCAACCTCTTCTACGCCGCCGGTTGCCGACCGCTGATCCTGGGCCCCGGCGCACTGGA
GATTTCGCACACCCCCGAAGAACAGGTCGACTTCCCCGAGGTCTTGGCGGCGGCACAGATCTATGCCGCGCTTTGCTTGG
GGCTCGACCGGTACGCGGTGCTGAACGTGGAGCGCTGCGGCTCCTGGGCTTCGTTCGACAGGCAGGGGAGCTGGGTGGGT
TGCCGGGATTAG

Upstream 100 bases:

>100_bases
TCAAGTTCTTTCAAAAGCATGGCTTCGACAACATCCAGGAGCACGTGTACATGACCCTGAACCTGTCCAAGAGAAGCAAG
AAGAAACCGGTGAAAAAGCC

Downstream 100 bases:

>100_bases
ACGCGGACCCCCTTGCCCTCCTGCTTCGTTTTCTGTAAGCTGCTTCAGTATTTCCATCCCAAACCGATACGATACCCCAG
GACAGGTTCCGCTGGAGTAT

Product: N-acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTGRLEEVFAAIDPARLKGTLLEMLDIYSPSGKEEDIQLYLEDLLAGAGFYVERQEVEEERYNLRVTMGEGEPELYLVGH
VDTVPAWDLEEFGARVEGDAIGGLGSADMKGGCAAMIEAWLAMAQALKPGRRPNVGLLLVVGEEENGDGSASFLKNCSPA
WAVIGEPTGLSACFAHYGYLEAGFVTHGLRSHSSLPELGHNAVESMLRVLLHLSKDPLFHREQGSIVYSIREMHSSQKGF
VVPDRCESWIDLHLPPELDPESVQRGISHIVSSAGQYIPGLDLNVAFNFASAGYNLGTDNPLSCILEQVYQRLGRTLKFD
SFRSHSDGNLFYAAGCRPLILGPGALEISHTPEEQVDFPEVLAAAQIYAALCLGLDRYAVLNVERCGSWASFDRQGSWVG
CRD

Sequences:

>Translated_403_residues
MTGRLEEVFAAIDPARLKGTLLEMLDIYSPSGKEEDIQLYLEDLLAGAGFYVERQEVEEERYNLRVTMGEGEPELYLVGH
VDTVPAWDLEEFGARVEGDAIGGLGSADMKGGCAAMIEAWLAMAQALKPGRRPNVGLLLVVGEEENGDGSASFLKNCSPA
WAVIGEPTGLSACFAHYGYLEAGFVTHGLRSHSSLPELGHNAVESMLRVLLHLSKDPLFHREQGSIVYSIREMHSSQKGF
VVPDRCESWIDLHLPPELDPESVQRGISHIVSSAGQYIPGLDLNVAFNFASAGYNLGTDNPLSCILEQVYQRLGRTLKFD
SFRSHSDGNLFYAAGCRPLILGPGALEISHTPEEQVDFPEVLAAAQIYAALCLGLDRYAVLNVERCGSWASFDRQGSWVG
CRD
>Mature_402_residues
TGRLEEVFAAIDPARLKGTLLEMLDIYSPSGKEEDIQLYLEDLLAGAGFYVERQEVEEERYNLRVTMGEGEPELYLVGHV
DTVPAWDLEEFGARVEGDAIGGLGSADMKGGCAAMIEAWLAMAQALKPGRRPNVGLLLVVGEEENGDGSASFLKNCSPAW
AVIGEPTGLSACFAHYGYLEAGFVTHGLRSHSSLPELGHNAVESMLRVLLHLSKDPLFHREQGSIVYSIREMHSSQKGFV
VPDRCESWIDLHLPPELDPESVQRGISHIVSSAGQYIPGLDLNVAFNFASAGYNLGTDNPLSCILEQVYQRLGRTLKFDS
FRSHSDGNLFYAAGCRPLILGPGALEISHTPEEQVDFPEVLAAAQIYAALCLGLDRYAVLNVERCGSWASFDRQGSWVGC
RD

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=373, Percent_Identity=26.0053619302949, Blast_Score=96, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17551016, Length=237, Percent_Identity=29.957805907173, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 44022; Mature: 43891

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRLEEVFAAIDPARLKGTLLEMLDIYSPSGKEEDIQLYLEDLLAGAGFYVERQEVEEE
CCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHH
RYNLRVTMGEGEPELYLVGHVDTVPAWDLEEFGARVEGDAIGGLGSADMKGGCAAMIEAW
HCEEEEEECCCCCCEEEEECCCCCCCCCHHHHCCEECCCCCCCCCCCCCCCHHHHHHHHH
LAMAQALKPGRRPNVGLLLVVGEEENGDGSASFLKNCSPAWAVIGEPTGLSACFAHYGYL
HHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCEEEEECCCCHHHHHHHHCCH
EAGFVTHGLRSHSSLPELGHNAVESMLRVLLHLSKDPLFHREQGSIVYSIREMHSSQKGF
HHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHCCCCCCC
VVPDRCESWIDLHLPPELDPESVQRGISHIVSSAGQYIPGLDLNVAFNFASAGYNLGTDN
CCCHHHCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCC
PLSCILEQVYQRLGRTLKFDSFRSHSDGNLFYAAGCRPLILGPGALEISHTPEEQVDFPE
HHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEECCCCEEEECCCEEEECCCCHHHCCHHH
VLAAAQIYAALCLGLDRYAVLNVERCGSWASFDRQGSWVGCRD
HHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGRLEEVFAAIDPARLKGTLLEMLDIYSPSGKEEDIQLYLEDLLAGAGFYVERQEVEEE
CCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHH
RYNLRVTMGEGEPELYLVGHVDTVPAWDLEEFGARVEGDAIGGLGSADMKGGCAAMIEAW
HCEEEEEECCCCCCEEEEECCCCCCCCCHHHHCCEECCCCCCCCCCCCCCCHHHHHHHHH
LAMAQALKPGRRPNVGLLLVVGEEENGDGSASFLKNCSPAWAVIGEPTGLSACFAHYGYL
HHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCEEEEECCCCHHHHHHHHCCH
EAGFVTHGLRSHSSLPELGHNAVESMLRVLLHLSKDPLFHREQGSIVYSIREMHSSQKGF
HHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHCCCCCCC
VVPDRCESWIDLHLPPELDPESVQRGISHIVSSAGQYIPGLDLNVAFNFASAGYNLGTDN
CCCHHHCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCC
PLSCILEQVYQRLGRTLKFDSFRSHSDGNLFYAAGCRPLILGPGALEISHTPEEQVDFPE
HHHHHHHHHHHHHCCCEECCCCCCCCCCCEEEECCCCEEEECCCEEEECCCCHHHCCHHH
VLAAAQIYAALCLGLDRYAVLNVERCGSWASFDRQGSWVGCRD
HHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA