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The map label for this gene is rpfG [H]

Identifier: 197119543

GI number: 197119543

Start: 3654608

End: 3656749

Strand: Direct

Name: rpfG [H]

Synonym: Gbem_3173

Alternate gene names: 197119543

Gene position: 3654608-3656749 (Clockwise)

Preceding gene: 308535354

Following gene: 197119544

Centisome position: 79.19

GC content: 56.63

Gene sequence:

>2142_bases
ATGAAACTCAACTTTGCATTCATACGAAGAGGAGTAGGAAGGCGCATCTTCGGCCTCTTCGTCGCCTGTGCACTGCTCCC
CGTGTGCGCCTTGGCGGTGCTGTCGCTGCGGCAGGTCGCCGAAAGCACCCGCAACGAAAGCCGTGTTCTGCTGAGGCACA
CCAGCAAAAACGCCGCCATGGCCATCCATCAAGTCCTGCTCATGCTGCAGATCGAGCTTAAAGCTCAGGCGTCTTCAGTC
ACAGGGGTCCCTTCCAGACCGGGGAGGGGTGAGCGCCAGGCGCTGTCCGAAAGCATGCAGGAAAGGCTCACGGCAGTCAC
CATGTTCAACCGGGGGAAAGCTAGAAACATCTTCGGCGCCCCCTGCCCGCTTCCGCAGCTGACTGCGACAGCGAAAGAGC
ATCTCGCCCTGGGGAAGATGCTGATGTTCTTGCAGGCAGCAGGAACGGGACCCAGTCGGATCTTCATCGCCACCTCTTTG
GACAAGAACCCAGACGAAACGCTTTTGGTTGGAGAGGTCAACGGGAGTTACCTCTGGGAGGTTGTCGGCTACACTCTTCC
ACCCGGCATATCCATCTGCATACTCGATCCGGCAGGCAAGGCGCTGTTCACCTCTGTTGCACCGGTGCCGGCTTTCATTG
AGCGGGTAAAGGCGGAGCTGACAAAATCGACCATCGGCGGTTTTGAGGCGCGCCAGGACAACAGGTCCTATCTCGTCAGT
TACTGGCAACTCTTCCTGGAATCTTCCTTCTGCGCCGAACCGCTTACCGTTGTCACCAGTCAGTCCGCCCATGACGCTTA
CCTTTCCTTCGGCAAATTTGCCCGTACCTTCTATCTGGTGGCGTCACTGACATTACTCGTGGTGATTTTCATAAGTAGCC
GGCAGATACGCAGGAATCTGCTTCCCCTCACCATCCTGAAGGAAGGGGCAGAGAAAATAAGCCAAGGGGATTTCGATCAC
AAGGTGACGATCAACAGTGACGACGAGTTTGCAAGACTCGCCGACTCTTTCAACGAGATGTCGGACCACCTGAAGATGCA
TTTTTACATTCTGACCGAGACGTCTCTTATCGTGCGAAAGGTACTGTCAGGCCACAACAATGAGGAAATCGTCGAAGCGG
TTTTGACTAACCTGCACACAATCATCCCATGCGACTGGATTTGCGTTTCTTTGATGCACCCGATGATCAAGGACATGACG
GTTAATTTCAGTAGCCGCTGCACGCCTGCAGGGCCCGAGGCCATTAAGCAGAGCGTCACCGTGCTGAAATCGCAAGAGAC
GTCGATGCTGCACAAAAACGGCGAGAGCCTGGAAGTCGCCGCAGGCGGCAAGCCTTTTAGCGCTTTCCTTGCCCCCATCG
CAGCGGAAGGGGCGCGGGACACTTTCCTCGTTCCCGTGTTTTTCAAAAAAAGCCTTTACGCGATCCTCACCCTGGGATAC
AGGCAGAAACCCGAGCACGTCCGCGAAGATCTGTTGCGGGCCCGGCAGATAGCGGACCAGATAGCGATAGCGCTCGAGAA
CGTCCGTCTCATCGAGGAATTGAACAACCTGAACCTGGGGACCATACGAGCCCTGGCCAATGCCGTCGACGCCAAATCCC
CCTGGACCTCGGGCCATTCCTTGAGGGTAACCAACATCGCCCTCAACATCGGCAGGGAATTGGGGCTTTCCGCGACGGAA
CTGGAATCGCTGCATAGAGGCGGATTGTTCCACGACATCGGCAAGATCGGCGTTCCCGAATCGATACTGGACAAGCCGGG
CAAACTGACAGACGAAGAGTTCGCAACGATACGCAAGCATCCCGAAATAGGTGTCGAGATCCTCAACCCTATCGAGGCGT
ACCACAAGCTCATTCCCATAGTGCTCCAGCATCATGAATGGTTTAACGGAAAAGGCTATCCCAATGGGCTGGCCGGAGAC
GCCATCTCGCCGCTTGCCCGCATCCTGGCAGTGGCGGACGTCTACGACGCCTTGATCTCCGACCGTCCTTACCGGCAGGG
ATGGGAGTTCGGGCGGGTGCTGTCGTATCTGGAGGAAAGCTCCGGGACCCAGTTCGACCCGGTAGTAATACAGGCGGTCC
TCAGAATGAGTAACCGCGGCACCCTGGAGTCTTCGCCCCTTCTCTACCAGGAGACGGCATGA

Upstream 100 bases:

>100_bases
CCGCACCCCGCTAAGCGCCGCGGAAAGCCATGACGACGTCATTCGTGCCAGCAATGGCGGGTTTATCGGCCTGGCATCGG
ATTTCTAGCAGGGGGCGGGC

Downstream 100 bases:

>100_bases
CGGTTGCGGCTTTAAAGGCGAGGTTGAAAGGCCATGAAAATCATCTGTCCTAACTGCCACCACCGGCACCGGGGGCACAT
ACCTCAAAGCACGATTACGC

Product: HAMP domain-containing cyclic diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 713; Mature: 713

Protein sequence:

>713_residues
MKLNFAFIRRGVGRRIFGLFVACALLPVCALAVLSLRQVAESTRNESRVLLRHTSKNAAMAIHQVLLMLQIELKAQASSV
TGVPSRPGRGERQALSESMQERLTAVTMFNRGKARNIFGAPCPLPQLTATAKEHLALGKMLMFLQAAGTGPSRIFIATSL
DKNPDETLLVGEVNGSYLWEVVGYTLPPGISICILDPAGKALFTSVAPVPAFIERVKAELTKSTIGGFEARQDNRSYLVS
YWQLFLESSFCAEPLTVVTSQSAHDAYLSFGKFARTFYLVASLTLLVVIFISSRQIRRNLLPLTILKEGAEKISQGDFDH
KVTINSDDEFARLADSFNEMSDHLKMHFYILTETSLIVRKVLSGHNNEEIVEAVLTNLHTIIPCDWICVSLMHPMIKDMT
VNFSSRCTPAGPEAIKQSVTVLKSQETSMLHKNGESLEVAAGGKPFSAFLAPIAAEGARDTFLVPVFFKKSLYAILTLGY
RQKPEHVREDLLRARQIADQIAIALENVRLIEELNNLNLGTIRALANAVDAKSPWTSGHSLRVTNIALNIGRELGLSATE
LESLHRGGLFHDIGKIGVPESILDKPGKLTDEEFATIRKHPEIGVEILNPIEAYHKLIPIVLQHHEWFNGKGYPNGLAGD
AISPLARILAVADVYDALISDRPYRQGWEFGRVLSYLEESSGTQFDPVVIQAVLRMSNRGTLESSPLLYQETA

Sequences:

>Translated_713_residues
MKLNFAFIRRGVGRRIFGLFVACALLPVCALAVLSLRQVAESTRNESRVLLRHTSKNAAMAIHQVLLMLQIELKAQASSV
TGVPSRPGRGERQALSESMQERLTAVTMFNRGKARNIFGAPCPLPQLTATAKEHLALGKMLMFLQAAGTGPSRIFIATSL
DKNPDETLLVGEVNGSYLWEVVGYTLPPGISICILDPAGKALFTSVAPVPAFIERVKAELTKSTIGGFEARQDNRSYLVS
YWQLFLESSFCAEPLTVVTSQSAHDAYLSFGKFARTFYLVASLTLLVVIFISSRQIRRNLLPLTILKEGAEKISQGDFDH
KVTINSDDEFARLADSFNEMSDHLKMHFYILTETSLIVRKVLSGHNNEEIVEAVLTNLHTIIPCDWICVSLMHPMIKDMT
VNFSSRCTPAGPEAIKQSVTVLKSQETSMLHKNGESLEVAAGGKPFSAFLAPIAAEGARDTFLVPVFFKKSLYAILTLGY
RQKPEHVREDLLRARQIADQIAIALENVRLIEELNNLNLGTIRALANAVDAKSPWTSGHSLRVTNIALNIGRELGLSATE
LESLHRGGLFHDIGKIGVPESILDKPGKLTDEEFATIRKHPEIGVEILNPIEAYHKLIPIVLQHHEWFNGKGYPNGLAGD
AISPLARILAVADVYDALISDRPYRQGWEFGRVLSYLEESSGTQFDPVVIQAVLRMSNRGTLESSPLLYQETA
>Mature_713_residues
MKLNFAFIRRGVGRRIFGLFVACALLPVCALAVLSLRQVAESTRNESRVLLRHTSKNAAMAIHQVLLMLQIELKAQASSV
TGVPSRPGRGERQALSESMQERLTAVTMFNRGKARNIFGAPCPLPQLTATAKEHLALGKMLMFLQAAGTGPSRIFIATSL
DKNPDETLLVGEVNGSYLWEVVGYTLPPGISICILDPAGKALFTSVAPVPAFIERVKAELTKSTIGGFEARQDNRSYLVS
YWQLFLESSFCAEPLTVVTSQSAHDAYLSFGKFARTFYLVASLTLLVVIFISSRQIRRNLLPLTILKEGAEKISQGDFDH
KVTINSDDEFARLADSFNEMSDHLKMHFYILTETSLIVRKVLSGHNNEEIVEAVLTNLHTIIPCDWICVSLMHPMIKDMT
VNFSSRCTPAGPEAIKQSVTVLKSQETSMLHKNGESLEVAAGGKPFSAFLAPIAAEGARDTFLVPVFFKKSLYAILTLGY
RQKPEHVREDLLRARQIADQIAIALENVRLIEELNNLNLGTIRALANAVDAKSPWTSGHSLRVTNIALNIGRELGLSATE
LESLHRGGLFHDIGKIGVPESILDKPGKLTDEEFATIRKHPEIGVEILNPIEAYHKLIPIVLQHHEWFNGKGYPNGLAGD
AISPLARILAVADVYDALISDRPYRQGWEFGRVLSYLEESSGTQFDPVVIQAVLRMSNRGTLESSPLLYQETA

Specific function: Positively regulates the synthesis of extracellular enzymes and extracellular polysaccharides. The cell-cell signaling system encoded by rpf genes is required for full virulence and is implicated in regulation of the formation and dispersal of biofilms [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR003607
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 78608; Mature: 78608

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNFAFIRRGVGRRIFGLFVACALLPVCALAVLSLRQVAESTRNESRVLLRHTSKNAAM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHH
AIHQVLLMLQIELKAQASSVTGVPSRPGRGERQALSESMQERLTAVTMFNRGKARNIFGA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PCPLPQLTATAKEHLALGKMLMFLQAAGTGPSRIFIATSLDKNPDETLLVGEVNGSYLWE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEHH
VVGYTLPPGISICILDPAGKALFTSVAPVPAFIERVKAELTKSTIGGFEARQDNRSYLVS
HHCCCCCCCCEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
YWQLFLESSFCAEPLTVVTSQSAHDAYLSFGKFARTFYLVASLTLLVVIFISSRQIRRNL
HHHHHHHHCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
LPLTILKEGAEKISQGDFDHKVTINSDDEFARLADSFNEMSDHLKMHFYILTETSLIVRK
CCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHH
VLSGHNNEEIVEAVLTNLHTIIPCDWICVSLMHPMIKDMTVNFSSRCTPAGPEAIKQSVT
HHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
VLKSQETSMLHKNGESLEVAAGGKPFSAFLAPIAAEGARDTFLVPVFFKKSLYAILTLGY
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCC
RQKPEHVREDLLRARQIADQIAIALENVRLIEELNNLNLGTIRALANAVDAKSPWTSGHS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
LRVTNIALNIGRELGLSATELESLHRGGLFHDIGKIGVPESILDKPGKLTDEEFATIRKH
EEEEEEEEEHHHHHCCCHHHHHHHHCCCCHHHHHCCCCCHHHHCCCCCCCHHHHHHHHCC
PEIGVEILNPIEAYHKLIPIVLQHHEWFNGKGYPNGLAGDAISPLARILAVADVYDALIS
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
DRPYRQGWEFGRVLSYLEESSGTQFDPVVIQAVLRMSNRGTLESSPLLYQETA
CCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCC
>Mature Secondary Structure
MKLNFAFIRRGVGRRIFGLFVACALLPVCALAVLSLRQVAESTRNESRVLLRHTSKNAAM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHH
AIHQVLLMLQIELKAQASSVTGVPSRPGRGERQALSESMQERLTAVTMFNRGKARNIFGA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PCPLPQLTATAKEHLALGKMLMFLQAAGTGPSRIFIATSLDKNPDETLLVGEVNGSYLWE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEHH
VVGYTLPPGISICILDPAGKALFTSVAPVPAFIERVKAELTKSTIGGFEARQDNRSYLVS
HHCCCCCCCCEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
YWQLFLESSFCAEPLTVVTSQSAHDAYLSFGKFARTFYLVASLTLLVVIFISSRQIRRNL
HHHHHHHHCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
LPLTILKEGAEKISQGDFDHKVTINSDDEFARLADSFNEMSDHLKMHFYILTETSLIVRK
CCHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHH
VLSGHNNEEIVEAVLTNLHTIIPCDWICVSLMHPMIKDMTVNFSSRCTPAGPEAIKQSVT
HHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
VLKSQETSMLHKNGESLEVAAGGKPFSAFLAPIAAEGARDTFLVPVFFKKSLYAILTLGY
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCC
RQKPEHVREDLLRARQIADQIAIALENVRLIEELNNLNLGTIRALANAVDAKSPWTSGHS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
LRVTNIALNIGRELGLSATELESLHRGGLFHDIGKIGVPESILDKPGKLTDEEFATIRKH
EEEEEEEEEHHHHHCCCHHHHHHHHCCCCHHHHHCCCCCHHHHCCCCCCCHHHHHHHHCC
PEIGVEILNPIEAYHKLIPIVLQHHEWFNGKGYPNGLAGDAISPLARILAVADVYDALIS
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
DRPYRQGWEFGRVLSYLEESSGTQFDPVVIQAVLRMSNRGTLESSPLLYQETA
CCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11123673 [H]