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The map label for this gene is lnt-2 [H]

Identifier: 197117213

GI number: 197117213

Start: 971682

End: 973238

Strand: Direct

Name: lnt-2 [H]

Synonym: Gbem_0821

Alternate gene names: 197117213

Gene position: 971682-973238 (Clockwise)

Preceding gene: 197117212

Following gene: 197117214

Centisome position: 21.05

GC content: 63.78

Gene sequence:

>1557_bases
TTGCTGAACAGCATTACCAGCCACCGCCTTTTCCCGTGGATAGCCGCAGTTGCCAGCGGCATCCTCCTTTTCCTGGGCTA
TGCCGGCTTCGACCAGTTCTACCTGGAGTGGATCTTCCTGGTGCCGCTTTTCTGGGCACTGCGCGACGCGCGCCCCGGGC
GCGCCTTTCTCATCGGCTGGGTTGCCGGTATCGTCGGGCACGGCGGCGGATTTTACTGGATCATCGACATGTTCAAGCAG
TTCGCCGGAGCCCCTCTCCCCTTTGCCCTGGTCGGGCTGGCGCTCCTGGCCGCGGCAAACGGCATCGTGGTTGCCGCCTG
GGCCTGGGGAATAAGGGTCATCGCCGCCCGAGGCTGGCAGGTTATCTGGGTCGCCCCGGTGGTCTGGACGGCGATGGAGA
AATTCTGGCCCGAGGTTTTCCCCAACTACCTCGGGGCGAGCCAGTACCGGCTGTCGCATCTGACGCAGATAGCGGATTTC
GCCGGGATCCTCGGGGTGAGCTTCCTCGTGGTCTACATCAACGCAACGCTTTACTGGGTGACCGCCTGCTGGTTCGAGGA
AAGGCGTCTCCCCTGGCGTGCGCTGTCGGCCTTGGCGCTATCGCTTCTGTTCGTGCTGGGGTACGGGGAGATGCGGCTTA
AGGAGGTGGAGCGGCAGGTAGCAACGGCGCAGACCCTCAAGGTCGGGCTGGTACAGGCCAACCGGGGTGCCGCAGACCTG
CACATCGACTCCGACACCGTGTTGCAGGAGCACCGGGACATGTCGCGGACCCTGGTGGAAAAGCAAAGGCCGGACCTGGT
GGTCTGGCCGGAAGGGGTGCCGGTGAGCCTTTCCTTCCGGGAAGGGGTGCTCCCCACCGCGGCACTCGGGGACCTGGGCA
CCCCGCTTCTCTTCGGCGCCTGCCTGCGGGTAGCCGGCGGGATCTGCAACAGCGCCTTTCTGGTCGACGCCTCCGGGCGC
ATCCTGGGGAGCTACGACAAGACGGTGCTGGTTCCTTTCGGGGAGTACATACCTTTTGGCGACACCTTCCCGAGCCTCTA
CTCCTGGTCCCCCTACTCGAGCCGCTTCTGGCGCGGCCAGAGCGAGGAGCCGCTCCGACTGGGAGATCGCGTGCTCTCGC
TCAGCATCTGCTATGAAGACATCTTCCCGCTGCACATCAGAAAACTCATGGCCGGCGGAAAGGAGAGACGCGTCCCCGAG
GCGATGTTCAACCTCACCAACGACTCATGGTACGGCAACTCGACCGAACCGGTGCAGCACCTGGCGCTGGCCAGCTTCCG
CTCCATCGAGAACCGCCGCTCCCTGGTACGCGTCACCAATACCGGCATTTCGGCTTTCGTGGATCCTGCCGGGCGCATCG
TCAAGAGTACCGGCATCTGGACCAAGGAGGTCCTGGTGGACAAGATCCCGCTGTTACAGGGAGGGCGCCCCCCATATTCG
GTGGCCGGAGACTGGATCGGCTGGCTCTGTGCCTTGCTCACTGCGTCAGCGATAACGTCGCCTATGTCTCGATGCGTCGC
CAGAGAGAAGCTGGAAAAGGGTAAGCCCTGCGTTTGA

Upstream 100 bases:

>100_bases
TTTCTGCTGTTTGTGAGATTGTGATGATTAAACGTTTGTGCTATCTTGACAGGCCGCACCGCCTCCAGCATCCATAATCC
CCGTTGATACCGAGGTCACC

Downstream 100 bases:

>100_bases
CTGAAAAACATAATGGACTATAGTGTCACAAGGCAAAAAAGGCATCGTCAATTCAAGTGCGGTGGCGACTGTGACTGCAC
CGGCCGCCCCTGAAAGCTCG

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MLNSITSHRLFPWIAAVASGILLFLGYAGFDQFYLEWIFLVPLFWALRDARPGRAFLIGWVAGIVGHGGGFYWIIDMFKQ
FAGAPLPFALVGLALLAAANGIVVAAWAWGIRVIAARGWQVIWVAPVVWTAMEKFWPEVFPNYLGASQYRLSHLTQIADF
AGILGVSFLVVYINATLYWVTACWFEERRLPWRALSALALSLLFVLGYGEMRLKEVERQVATAQTLKVGLVQANRGAADL
HIDSDTVLQEHRDMSRTLVEKQRPDLVVWPEGVPVSLSFREGVLPTAALGDLGTPLLFGACLRVAGGICNSAFLVDASGR
ILGSYDKTVLVPFGEYIPFGDTFPSLYSWSPYSSRFWRGQSEEPLRLGDRVLSLSICYEDIFPLHIRKLMAGGKERRVPE
AMFNLTNDSWYGNSTEPVQHLALASFRSIENRRSLVRVTNTGISAFVDPAGRIVKSTGIWTKEVLVDKIPLLQGGRPPYS
VAGDWIGWLCALLTASAITSPMSRCVAREKLEKGKPCV

Sequences:

>Translated_518_residues
MLNSITSHRLFPWIAAVASGILLFLGYAGFDQFYLEWIFLVPLFWALRDARPGRAFLIGWVAGIVGHGGGFYWIIDMFKQ
FAGAPLPFALVGLALLAAANGIVVAAWAWGIRVIAARGWQVIWVAPVVWTAMEKFWPEVFPNYLGASQYRLSHLTQIADF
AGILGVSFLVVYINATLYWVTACWFEERRLPWRALSALALSLLFVLGYGEMRLKEVERQVATAQTLKVGLVQANRGAADL
HIDSDTVLQEHRDMSRTLVEKQRPDLVVWPEGVPVSLSFREGVLPTAALGDLGTPLLFGACLRVAGGICNSAFLVDASGR
ILGSYDKTVLVPFGEYIPFGDTFPSLYSWSPYSSRFWRGQSEEPLRLGDRVLSLSICYEDIFPLHIRKLMAGGKERRVPE
AMFNLTNDSWYGNSTEPVQHLALASFRSIENRRSLVRVTNTGISAFVDPAGRIVKSTGIWTKEVLVDKIPLLQGGRPPYS
VAGDWIGWLCALLTASAITSPMSRCVAREKLEKGKPCV
>Mature_518_residues
MLNSITSHRLFPWIAAVASGILLFLGYAGFDQFYLEWIFLVPLFWALRDARPGRAFLIGWVAGIVGHGGGFYWIIDMFKQ
FAGAPLPFALVGLALLAAANGIVVAAWAWGIRVIAARGWQVIWVAPVVWTAMEKFWPEVFPNYLGASQYRLSHLTQIADF
AGILGVSFLVVYINATLYWVTACWFEERRLPWRALSALALSLLFVLGYGEMRLKEVERQVATAQTLKVGLVQANRGAADL
HIDSDTVLQEHRDMSRTLVEKQRPDLVVWPEGVPVSLSFREGVLPTAALGDLGTPLLFGACLRVAGGICNSAFLVDASGR
ILGSYDKTVLVPFGEYIPFGDTFPSLYSWSPYSSRFWRGQSEEPLRLGDRVLSLSICYEDIFPLHIRKLMAGGKERRVPE
AMFNLTNDSWYGNSTEPVQHLALASFRSIENRRSLVRVTNTGISAFVDPAGRIVKSTGIWTKEVLVDKIPLLQGGRPPYS
VAGDWIGWLCALLTASAITSPMSRCVAREKLEKGKPCV

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=481, Percent_Identity=26.8191268191268, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 57406; Mature: 57406

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNSITSHRLFPWIAAVASGILLFLGYAGFDQFYLEWIFLVPLFWALRDARPGRAFLIGW
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VAGIVGHGGGFYWIIDMFKQFAGAPLPFALVGLALLAAANGIVVAAWAWGIRVIAARGWQ
HHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHEECCCE
VIWVAPVVWTAMEKFWPEVFPNYLGASQYRLSHLTQIADFAGILGVSFLVVYINATLYWV
EEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TACWFEERRLPWRALSALALSLLFVLGYGEMRLKEVERQVATAQTLKVGLVQANRGAADL
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCEE
HIDSDTVLQEHRDMSRTLVEKQRPDLVVWPEGVPVSLSFREGVLPTAALGDLGTPLLFGA
EECCHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCHHHHCCCHHHHHHH
CLRVAGGICNSAFLVDASGRILGSYDKTVLVPFGEYIPFGDTFPSLYSWSPYSSRFWRGQ
HHHHHCCCCCCEEEEECCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCC
SEEPLRLGDRVLSLSICYEDIFPLHIRKLMAGGKERRVPEAMFNLTNDSWYGNSTEPVQH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCHHHH
LALASFRSIENRRSLVRVTNTGISAFVDPAGRIVKSTGIWTKEVLVDKIPLLQGGRPPYS
HHHHHHHHHHHHHHEEEEECCCCHHHCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
VAGDWIGWLCALLTASAITSPMSRCVAREKLEKGKPCV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLNSITSHRLFPWIAAVASGILLFLGYAGFDQFYLEWIFLVPLFWALRDARPGRAFLIGW
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VAGIVGHGGGFYWIIDMFKQFAGAPLPFALVGLALLAAANGIVVAAWAWGIRVIAARGWQ
HHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHEECCCE
VIWVAPVVWTAMEKFWPEVFPNYLGASQYRLSHLTQIADFAGILGVSFLVVYINATLYWV
EEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TACWFEERRLPWRALSALALSLLFVLGYGEMRLKEVERQVATAQTLKVGLVQANRGAADL
HHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCEE
HIDSDTVLQEHRDMSRTLVEKQRPDLVVWPEGVPVSLSFREGVLPTAALGDLGTPLLFGA
EECCHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCCCCHHHHCCCHHHHHHH
CLRVAGGICNSAFLVDASGRILGSYDKTVLVPFGEYIPFGDTFPSLYSWSPYSSRFWRGQ
HHHHHCCCCCCEEEEECCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCC
SEEPLRLGDRVLSLSICYEDIFPLHIRKLMAGGKERRVPEAMFNLTNDSWYGNSTEPVQH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCHHHH
LALASFRSIENRRSLVRVTNTGISAFVDPAGRIVKSTGIWTKEVLVDKIPLLQGGRPPYS
HHHHHHHHHHHHHHEEEEECCCCHHHCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
VAGDWIGWLCALLTASAITSPMSRCVAREKLEKGKPCV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA