Click here to switch to the map view.

The map label for this gene is mcp014 [H]

Identifier: 197117201

GI number: 197117201

Start: 958558

End: 960156

Strand: Reverse

Name: mcp014 [H]

Synonym: Gbem_0809

Alternate gene names: 197117201

Gene position: 960156-958558 (Counterclockwise)

Preceding gene: 197117203

Following gene: 197117199

Centisome position: 20.8

GC content: 60.04

Gene sequence:

>1599_bases
ATGAACATAAGCAAGAAGATTCTGATCAGCAACGTGGGCATGGTGCTCATCGCGACCATTACCACTTCGGCTATTTCGCT
CTACGTCACCAAGAAGGAGATCACGCGCCAGGTCAACGTTTCACTCGGCTCGCGGATCAAGGCTTTCCGCGAACTTATCG
GCAAAAGCGATGGCAGCATAGTGTTGGTGGACGGCAAGCTACAGGCCAACGGTGTGACGTTGGACGGCGACAACGCCCTG
ACCGACAGGATGAAAGAGATCTTCGGGGGGGAGGCGACCATCTTCAGGGACGACGTCCGAGTCGCGACAACGATCAAGAA
GGAGGACGGCTCGCGAGCGGTCGGCACCAAGCTTCAGGGACCCGCGCGCGAGGCGGTCGTCGATCGGGCGGTTCCCTACC
AGGGGGAGGCAAGCATTCTGGGGGTTCCGCATTTTGCCTCCTATCTCCCCCTTAAAGACGGCAACGGCAAGGTGATTGGC
GCTCTTTTCGTCGGCGAGAAAAAGTCCGAGTACCTGGCGGTATTCGAGAAACTGAAATACCTGATCCTCGCGCTGTCCGC
ACTGCTCGGCGGAACCCTGGCGCTGGCGGGCTACCTGGCTCTGCACAAGGCGCTGATGCCGCTGCGAGAGCTGATCCGGA
CTCTGCAGAATGTAGCGGAAGGGGACGGTGACCTCACCCATCGCCTTAACGAATCCGACGATGAGATAGGTGCCGCCAGC
CGCTATTTCAACCGGTTCATCGACCGGGTCCACACCATTGTGCAGACGGTGGCCGACAACGCTAACTCCGTGGCGAGCGC
GAGTTCCGAGTTGCACTCCAGCACAGAGAGGCTTGCCGACACCACCGAGGCAGTAGCCGTGCAGACAGAAACCGTATCGA
CCGCCGGCGAGGAGATGGCTGCCACTTCCGCGGACATCTCCAAGAACTGCCTGAGCGCGGTCGACAGCGCCCAGCGAGCC
TGCGAGATGGCGCGCTATGGCTCCGCCGACGTCGAGCGCACCATCGAAGGGATGAAGCTCATCAACGAGAAGGTGCGAGC
CACCTCTGAGAGCGTCGGCAATCTGGGGGTAAAGTCGGAACAAATCGGCGACATCATCGGCACCATCCAGGACATCGCGG
ACCAGACCAATCTGCTGGCCTTGAACGCGGCGATAGAGGCGGCTCGCGCCGGTGAGCAGGGGCGCGGCTTTGCGGTCGTG
GCAGACGAGGTGCGCCGCTTAGCCGAAAGGACCACCAGCGCCACCAAGGAGATCGAGGTCAACATAAGGTCGATTCAAGA
AGAGACCGCCCGGGCAGTGCAAGTAATGCACGAAAGCGCACGGGAAGCTGCAAAGGGGGCCGAAGACTCTGTCAAGTCAG
GGGAGAGCCTGGGGGAAATTCTGAAACAGGTAAACGAGGTGACGCTGCAGATAGGGCAGATAGCAACGGCTGCCGAAGAG
CAGAGCGCGACGAGCCGCGAGATCAGCAATAACGTGCACCAGATTACCGGGATCATTCAGGGCGCAGCCAGGGAAAACCG
TGCATCCATGTCGACTGCGGACGAGTTGAACCGGCTCTCGGAGAGTCTGAGGCTGCAGATCTGCAGATTCAGGTATTAA

Upstream 100 bases:

>100_bases
GACCCGTATACTTTTTCTAAAGATTGCTCCGCTAACCCCGATAGGTCTTTTCGAAGCTTCCGTTGTCACCACCCCAAACA
CGCGCAACAAAGGGACCAGC

Downstream 100 bases:

>100_bases
GCCGCCCTCCCCTTCCTGGCGGGGGGAGACGGCGCGCAGCCGCTACTAGTCGGGGAGACGCCAATCTATAGGATCCCTTC
CGTGCCGTGCCAGGTAGGCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MNISKKILISNVGMVLIATITTSAISLYVTKKEITRQVNVSLGSRIKAFRELIGKSDGSIVLVDGKLQANGVTLDGDNAL
TDRMKEIFGGEATIFRDDVRVATTIKKEDGSRAVGTKLQGPAREAVVDRAVPYQGEASILGVPHFASYLPLKDGNGKVIG
ALFVGEKKSEYLAVFEKLKYLILALSALLGGTLALAGYLALHKALMPLRELIRTLQNVAEGDGDLTHRLNESDDEIGAAS
RYFNRFIDRVHTIVQTVADNANSVASASSELHSSTERLADTTEAVAVQTETVSTAGEEMAATSADISKNCLSAVDSAQRA
CEMARYGSADVERTIEGMKLINEKVRATSESVGNLGVKSEQIGDIIGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVV
ADEVRRLAERTTSATKEIEVNIRSIQEETARAVQVMHESAREAAKGAEDSVKSGESLGEILKQVNEVTLQIGQIATAAEE
QSATSREISNNVHQITGIIQGAARENRASMSTADELNRLSESLRLQICRFRY

Sequences:

>Translated_532_residues
MNISKKILISNVGMVLIATITTSAISLYVTKKEITRQVNVSLGSRIKAFRELIGKSDGSIVLVDGKLQANGVTLDGDNAL
TDRMKEIFGGEATIFRDDVRVATTIKKEDGSRAVGTKLQGPAREAVVDRAVPYQGEASILGVPHFASYLPLKDGNGKVIG
ALFVGEKKSEYLAVFEKLKYLILALSALLGGTLALAGYLALHKALMPLRELIRTLQNVAEGDGDLTHRLNESDDEIGAAS
RYFNRFIDRVHTIVQTVADNANSVASASSELHSSTERLADTTEAVAVQTETVSTAGEEMAATSADISKNCLSAVDSAQRA
CEMARYGSADVERTIEGMKLINEKVRATSESVGNLGVKSEQIGDIIGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVV
ADEVRRLAERTTSATKEIEVNIRSIQEETARAVQVMHESAREAAKGAEDSVKSGESLGEILKQVNEVTLQIGQIATAAEE
QSATSREISNNVHQITGIIQGAARENRASMSTADELNRLSESLRLQICRFRY
>Mature_532_residues
MNISKKILISNVGMVLIATITTSAISLYVTKKEITRQVNVSLGSRIKAFRELIGKSDGSIVLVDGKLQANGVTLDGDNAL
TDRMKEIFGGEATIFRDDVRVATTIKKEDGSRAVGTKLQGPAREAVVDRAVPYQGEASILGVPHFASYLPLKDGNGKVIG
ALFVGEKKSEYLAVFEKLKYLILALSALLGGTLALAGYLALHKALMPLRELIRTLQNVAEGDGDLTHRLNESDDEIGAAS
RYFNRFIDRVHTIVQTVADNANSVASASSELHSSTERLADTTEAVAVQTETVSTAGEEMAATSADISKNCLSAVDSAQRA
CEMARYGSADVERTIEGMKLINEKVRATSESVGNLGVKSEQIGDIIGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVV
ADEVRRLAERTTSATKEIEVNIRSIQEETARAVQVMHESAREAAKGAEDSVKSGESLGEILKQVNEVTLQIGQIATAAEE
QSATSREISNNVHQITGIIQGAARENRASMSTADELNRLSESLRLQICRFRY

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=290, Percent_Identity=33.1034482758621, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787690, Length=355, Percent_Identity=32.112676056338, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1788195, Length=282, Percent_Identity=33.6879432624113, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789453, Length=343, Percent_Identity=26.8221574344023, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788194, Length=256, Percent_Identity=35.15625, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57093; Mature: 57093

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISKKILISNVGMVLIATITTSAISLYVTKKEITRQVNVSLGSRIKAFRELIGKSDGSI
CCCCHHHHHHCCCHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VLVDGKLQANGVTLDGDNALTDRMKEIFGGEATIFRDDVRVATTIKKEDGSRAVGTKLQG
EEEECEEEECCEEECCCHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCCCCCCC
PAREAVVDRAVPYQGEASILGVPHFASYLPLKDGNGKVIGALFVGEKKSEYLAVFEKLKY
CHHHHHHHHCCCCCCCCCEEECCHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
LILALSALLGGTLALAGYLALHKALMPLRELIRTLQNVAEGDGDLTHRLNESDDEIGAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHH
RYFNRFIDRVHTIVQTVADNANSVASASSELHSSTERLADTTEAVAVQTETVSTAGEEMA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHCCHHHH
ATSADISKNCLSAVDSAQRACEMARYGSADVERTIEGMKLINEKVRATSESVGNLGVKSE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
QIGDIIGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRRLAERTTSATKEIEV
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCHHHHHH
NIRSIQEETARAVQVMHESAREAAKGAEDSVKSGESLGEILKQVNEVTLQIGQIATAAEE
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSATSREISNNVHQITGIIQGAARENRASMSTADELNRLSESLRLQICRFRY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNISKKILISNVGMVLIATITTSAISLYVTKKEITRQVNVSLGSRIKAFRELIGKSDGSI
CCCCHHHHHHCCCHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VLVDGKLQANGVTLDGDNALTDRMKEIFGGEATIFRDDVRVATTIKKEDGSRAVGTKLQG
EEEECEEEECCEEECCCHHHHHHHHHHHCCCCEEEECCCEEEEEEECCCCCCCCCCCCCC
PAREAVVDRAVPYQGEASILGVPHFASYLPLKDGNGKVIGALFVGEKKSEYLAVFEKLKY
CHHHHHHHHCCCCCCCCCEEECCHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
LILALSALLGGTLALAGYLALHKALMPLRELIRTLQNVAEGDGDLTHRLNESDDEIGAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHH
RYFNRFIDRVHTIVQTVADNANSVASASSELHSSTERLADTTEAVAVQTETVSTAGEEMA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHCCHHHH
ATSADISKNCLSAVDSAQRACEMARYGSADVERTIEGMKLINEKVRATSESVGNLGVKSE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
QIGDIIGTIQDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRRLAERTTSATKEIEV
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCHHHHHH
NIRSIQEETARAVQVMHESAREAAKGAEDSVKSGESLGEILKQVNEVTLQIGQIATAAEE
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSATSREISNNVHQITGIIQGAARENRASMSTADELNRLSESLRLQICRFRY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]