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The map label for this gene is arcB [H]

Identifier: 197117203

GI number: 197117203

Start: 960815

End: 962989

Strand: Reverse

Name: arcB [H]

Synonym: Gbem_0811

Alternate gene names: 197117203

Gene position: 962989-960815 (Counterclockwise)

Preceding gene: 197117204

Following gene: 197117201

Centisome position: 20.87

GC content: 60.41

Gene sequence:

>2175_bases
ATGGATCGCAATGAGAGCGCACAGACGCAGGTCCGTAAGCTTCAGGAGAGGGTGAACTTCCTCGAGGAAACCAACCTGAA
CTACCTGAAGACGCTCGACGTGCTCACCGCATGCAGCGACTTTCAGTCGGACATCTACCGGCAGAAGGAACCCTCCTTCG
TGATCAAGGCGGTCTTCGGCCAGTTGAAGCGGCTGATACCTTTCACCGCTCTCGGCATGCTCGGCATCGAAGCGGACGCT
TCCTTCAGCCTCACCGTCTGCGACCCCGAATTCTCTTGTGGCGAGGTCATGAACGAGGTCGACGCGCGGGTGCAGGACGG
CACCTTCGCCTGGGCCGTCAACCAGAACCACCCTGTAGTGGTGCCGACGCTCACCGGCACCGACACGCTCGTGCTGCACG
TTCTCGCCACCAACAGCCGCATCAGGGGGATGTTCGTGGGGATCCTTCCCGGCAGCCACCTAAGCGCCGAGGTCTCCACC
CTCAACGCCCTGAGCAGCATACTGATCAACACGGCATATGCGGTGGAGAACTCCGAGCTCTACGACATGCTGCAGGAACA
CATGCAGAATCTGGAAATGAAGGTCGCCCAGCGCACTACCGAACTTGAAGAAGCGCTGGTCAAGGCCGAGGCCGCCACCG
CGGCAAAGAGCGTCTTTTTGGCCAACATGAGCCACGAGATCAGGACGCCGATGAACGGGGTGATCGGCCTTGCCAAGCTG
CTGATGGAGACACCGCTTGACAAGGTGCAGCAAGGCTACATGGAGTCGCTTTCCGATTGCGCCGAAAACCTCCTCACCAT
CATCAACGAGATCCTCGACGTCTCCAAGGTTGAAGCCGGCATGATAACGCTGGAGGCTATCGTCTTCGACCTGAGGCGTT
TCCTGGACCGCTCGCTGCAGCCGTTCGTGCTCCGCGGCCAGGAAAAAGGAGTCCGGGTCCGGTTGGAGGCGTACCCGGGG
CTTCCTGAACTGGTGCTGGGGGATCCGGTTCGACTCCGGCAGATACTTGGGAACCTCCTGGGAAATGCGCTCAAATTCAC
CCAGAAGGGGAGCATCACCCTGACTGCCGCCTTGACGGGGAGCGGAGAGAACGGCGTCGGATTGAAGTTCTCCGTCGCCG
ACACAGGTATCGGCATAGCCCCGGAAGCGATAGAAGTCATCTTCGAGAAATTCTCCCAGGCCGACAGCTCCACCACCCGC
CTCTACGGCGGGACCGGGTTGGGGCTTTCCATCAGCAAAAGCCTGGTCGAACTGATGGGGGGGGAACTCAGCGTGCAAAG
CGCGCTGGGAAAAGGGAGCGTTTTCAGCTTCTGTATCGAGTTGAGCCAGCCGAAAGCCGGCGAGCGTCCCGCCGAGGAAG
AGGGCGAAGCGCCGGGCGCTAGGGTCGAACGTGAGTTGAAGATCCTCGTGGTGGACGACGTGCCGATCAACCAACTGATC
TCCGCAAAGCTCATCGCCAAAACAGGAAACCACCGGATCTCCACCGCGCAAAACGGACAAGAGGCCGTGGAAAAGTGGGA
ACGGGAGAAGTTCGACCTCATCTTTATGGATGTGCAGATGCCGGTCATGGACGGGCTGGAAGCGACCCGGATCATCAGGA
GCCGAGAGCAAGGGACCGGGTGGCGGGTCCACATCTGCGCTATGACCGCCAATGCGATGAAGGAGGACATCACCATCTGT
AACGATGCCGGCATGGACAGCTATCTGTCGAAGCCGGTGCGGGAGCGGGAAATCGCCTCCATGATCCGGAAGGTGGCCAC
CTCCGACGCTCTCCACCCCACCGGGTCCGCCGCCACTCCCTCCCCGGTGCCAGAAGCAGCACCTCTCCCGGCCTTTGATC
GGGCCGACCTCCTGGAGCGCCTGGGGGGGGAAGAGAAAGTGGTGGGGATGTTCGTGGTGAAATTCATCACGGCGGTAACC
GAGCACCTGGATCAACTGAAGGAGGCTGTCTCGGACCGGGATCTTGCGGCAGTCTATTACCGTGCCCACACCATAGCCGG
AACATCCGCCAATATGGGGGCGCCCCTGATGCGTGAACTCGCCGCAAGGATGGAGTCCGCAGCCAAGACAGAGGATGCTG
AGCCTCTCGAAGCCCTTTTCCTTCAGTTGCAGCAGGCCTTTTCCGCCTTCAAGTCCGAAAGCGCAGACAGCGCCGTAATC
CCCCCTACTTCATAA

Upstream 100 bases:

>100_bases
TGGGACCGGCTGCAGATCTCCTGCTACTTCCTTCCCACACTGGTGAAACAGGTGGACAGCACCTATGAACAGACCGTATC
GGTACTGTTCGGGAGTGAAG

Downstream 100 bases:

>100_bases
AAAAAGAGATGGAGGCCGGCGGCCCCCATCTCTTGTCATGCAACTTCCGGCACTCTCTTTCAGGCGCCGTTACTGATCAG
CATCTCCAGCGTACGCGTTG

Product: Hpt domain-containing sensor histidine kinase response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 724

Protein sequence:

>724_residues
MDRNESAQTQVRKLQERVNFLEETNLNYLKTLDVLTACSDFQSDIYRQKEPSFVIKAVFGQLKRLIPFTALGMLGIEADA
SFSLTVCDPEFSCGEVMNEVDARVQDGTFAWAVNQNHPVVVPTLTGTDTLVLHVLATNSRIRGMFVGILPGSHLSAEVST
LNALSSILINTAYAVENSELYDMLQEHMQNLEMKVAQRTTELEEALVKAEAATAAKSVFLANMSHEIRTPMNGVIGLAKL
LMETPLDKVQQGYMESLSDCAENLLTIINEILDVSKVEAGMITLEAIVFDLRRFLDRSLQPFVLRGQEKGVRVRLEAYPG
LPELVLGDPVRLRQILGNLLGNALKFTQKGSITLTAALTGSGENGVGLKFSVADTGIGIAPEAIEVIFEKFSQADSSTTR
LYGGTGLGLSISKSLVELMGGELSVQSALGKGSVFSFCIELSQPKAGERPAEEEGEAPGARVERELKILVVDDVPINQLI
SAKLIAKTGNHRISTAQNGQEAVEKWEREKFDLIFMDVQMPVMDGLEATRIIRSREQGTGWRVHICAMTANAMKEDITIC
NDAGMDSYLSKPVREREIASMIRKVATSDALHPTGSAATPSPVPEAAPLPAFDRADLLERLGGEEKVVGMFVVKFITAVT
EHLDQLKEAVSDRDLAAVYYRAHTIAGTSANMGAPLMRELAARMESAAKTEDAEPLEALFLQLQQAFSAFKSESADSAVI
PPTS

Sequences:

>Translated_724_residues
MDRNESAQTQVRKLQERVNFLEETNLNYLKTLDVLTACSDFQSDIYRQKEPSFVIKAVFGQLKRLIPFTALGMLGIEADA
SFSLTVCDPEFSCGEVMNEVDARVQDGTFAWAVNQNHPVVVPTLTGTDTLVLHVLATNSRIRGMFVGILPGSHLSAEVST
LNALSSILINTAYAVENSELYDMLQEHMQNLEMKVAQRTTELEEALVKAEAATAAKSVFLANMSHEIRTPMNGVIGLAKL
LMETPLDKVQQGYMESLSDCAENLLTIINEILDVSKVEAGMITLEAIVFDLRRFLDRSLQPFVLRGQEKGVRVRLEAYPG
LPELVLGDPVRLRQILGNLLGNALKFTQKGSITLTAALTGSGENGVGLKFSVADTGIGIAPEAIEVIFEKFSQADSSTTR
LYGGTGLGLSISKSLVELMGGELSVQSALGKGSVFSFCIELSQPKAGERPAEEEGEAPGARVERELKILVVDDVPINQLI
SAKLIAKTGNHRISTAQNGQEAVEKWEREKFDLIFMDVQMPVMDGLEATRIIRSREQGTGWRVHICAMTANAMKEDITIC
NDAGMDSYLSKPVREREIASMIRKVATSDALHPTGSAATPSPVPEAAPLPAFDRADLLERLGGEEKVVGMFVVKFITAVT
EHLDQLKEAVSDRDLAAVYYRAHTIAGTSANMGAPLMRELAARMESAAKTEDAEPLEALFLQLQQAFSAFKSESADSAVI
PPTS
>Mature_724_residues
MDRNESAQTQVRKLQERVNFLEETNLNYLKTLDVLTACSDFQSDIYRQKEPSFVIKAVFGQLKRLIPFTALGMLGIEADA
SFSLTVCDPEFSCGEVMNEVDARVQDGTFAWAVNQNHPVVVPTLTGTDTLVLHVLATNSRIRGMFVGILPGSHLSAEVST
LNALSSILINTAYAVENSELYDMLQEHMQNLEMKVAQRTTELEEALVKAEAATAAKSVFLANMSHEIRTPMNGVIGLAKL
LMETPLDKVQQGYMESLSDCAENLLTIINEILDVSKVEAGMITLEAIVFDLRRFLDRSLQPFVLRGQEKGVRVRLEAYPG
LPELVLGDPVRLRQILGNLLGNALKFTQKGSITLTAALTGSGENGVGLKFSVADTGIGIAPEAIEVIFEKFSQADSSTTR
LYGGTGLGLSISKSLVELMGGELSVQSALGKGSVFSFCIELSQPKAGERPAEEEGEAPGARVERELKILVVDDVPINQLI
SAKLIAKTGNHRISTAQNGQEAVEKWEREKFDLIFMDVQMPVMDGLEATRIIRSREQGTGWRVHICAMTANAMKEDITIC
NDAGMDSYLSKPVREREIASMIRKVATSDALHPTGSAATPSPVPEAAPLPAFDRADLLERLGGEEKVVGMFVVKFITAVT
EHLDQLKEAVSDRDLAAVYYRAHTIAGTSANMGAPLMRELAARMESAAKTEDAEPLEALFLQLQQAFSAFKSESADSAVI
PPTS

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=481, Percent_Identity=31.8087318087318, Blast_Score=226, Evalue=6e-60,
Organism=Escherichia coli, GI1789149, Length=310, Percent_Identity=39.0322580645161, Blast_Score=207, Evalue=3e-54,
Organism=Escherichia coli, GI1788713, Length=371, Percent_Identity=36.3881401617251, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI87081816, Length=521, Percent_Identity=30.3262955854127, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=37.8600823045267, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=31.5789473684211, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=32.034632034632, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786783, Length=252, Percent_Identity=26.5873015873016, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=252, Percent_Identity=26.5873015873016, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=27.0386266094421, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082128, Length=258, Percent_Identity=29.0697674418605, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787894, Length=239, Percent_Identity=29.7071129707113, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=27.4336283185841, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788279, Length=256, Percent_Identity=25.78125, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788549, Length=231, Percent_Identity=23.8095238095238, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=238, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=30.8943089430894, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1789808, Length=216, Percent_Identity=28.2407407407407, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=125, Percent_Identity=36.8, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323034, Length=157, Percent_Identity=33.1210191082803, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=121, Percent_Identity=29.7520661157025, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78771; Mature: 78771

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRNESAQTQVRKLQERVNFLEETNLNYLKTLDVLTACSDFQSDIYRQKEPSFVIKAVFG
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QLKRLIPFTALGMLGIEADASFSLTVCDPEFSCGEVMNEVDARVQDGTFAWAVNQNHPVV
HHHHHHHHHHHHHHEEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEE
VPTLTGTDTLVLHVLATNSRIRGMFVGILPGSHLSAEVSTLNALSSILINTAYAVENSEL
EEEECCCCEEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
YDMLQEHMQNLEMKVAQRTTELEEALVKAEAATAAKSVFLANMSHEIRTPMNGVIGLAKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHH
LMETPLDKVQQGYMESLSDCAENLLTIINEILDVSKVEAGMITLEAIVFDLRRFLDRSLQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PFVLRGQEKGVRVRLEAYPGLPELVLGDPVRLRQILGNLLGNALKFTQKGSITLTAALTG
CEEEECCCCCEEEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
SGENGVGLKFSVADTGIGIAPEAIEVIFEKFSQADSSTTRLYGGTGLGLSISKSLVELMG
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHC
GELSVQSALGKGSVFSFCIELSQPKAGERPAEEEGEAPGARVERELKILVVDDVPINQLI
CCEEHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHH
SAKLIAKTGNHRISTAQNGQEAVEKWEREKFDLIFMDVQMPVMDGLEATRIIRSREQGTG
HHHHHHHCCCCEECCCCCCHHHHHHHHCCCCCEEEEEECCHHHCCHHHHHHHHHHCCCCC
WRVHICAMTANAMKEDITICNDAGMDSYLSKPVREREIASMIRKVATSDALHPTGSAATP
EEEEEEEEEHHHHHHCCEEECCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SPVPEAAPLPAFDRADLLERLGGEEKVVGMFVVKFITAVTEHLDQLKEAVSDRDLAAVYY
CCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RAHTIAGTSANMGAPLMRELAARMESAAKTEDAEPLEALFLQLQQAFSAFKSESADSAVI
HHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
PPTS
CCCC
>Mature Secondary Structure
MDRNESAQTQVRKLQERVNFLEETNLNYLKTLDVLTACSDFQSDIYRQKEPSFVIKAVFG
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QLKRLIPFTALGMLGIEADASFSLTVCDPEFSCGEVMNEVDARVQDGTFAWAVNQNHPVV
HHHHHHHHHHHHHHEEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEE
VPTLTGTDTLVLHVLATNSRIRGMFVGILPGSHLSAEVSTLNALSSILINTAYAVENSEL
EEEECCCCEEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHH
YDMLQEHMQNLEMKVAQRTTELEEALVKAEAATAAKSVFLANMSHEIRTPMNGVIGLAKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHH
LMETPLDKVQQGYMESLSDCAENLLTIINEILDVSKVEAGMITLEAIVFDLRRFLDRSLQ
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PFVLRGQEKGVRVRLEAYPGLPELVLGDPVRLRQILGNLLGNALKFTQKGSITLTAALTG
CEEEECCCCCEEEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
SGENGVGLKFSVADTGIGIAPEAIEVIFEKFSQADSSTTRLYGGTGLGLSISKSLVELMG
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHC
GELSVQSALGKGSVFSFCIELSQPKAGERPAEEEGEAPGARVERELKILVVDDVPINQLI
CCEEHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHH
SAKLIAKTGNHRISTAQNGQEAVEKWEREKFDLIFMDVQMPVMDGLEATRIIRSREQGTG
HHHHHHHCCCCEECCCCCCHHHHHHHHCCCCCEEEEEECCHHHCCHHHHHHHHHHCCCCC
WRVHICAMTANAMKEDITICNDAGMDSYLSKPVREREIASMIRKVATSDALHPTGSAATP
EEEEEEEEEHHHHHHCCEEECCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SPVPEAAPLPAFDRADLLERLGGEEKVVGMFVVKFITAVTEHLDQLKEAVSDRDLAAVYY
CCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RAHTIAGTSANMGAPLMRELAARMESAAKTEDAEPLEALFLQLQQAFSAFKSESADSAVI
HHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
PPTS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]