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The map label for this gene is bdhA [H]

Identifier: 197117175

GI number: 197117175

Start: 915981

End: 917168

Strand: Direct

Name: bdhA [H]

Synonym: Gbem_0781

Alternate gene names: 197117175

Gene position: 915981-917168 (Clockwise)

Preceding gene: 197117164

Following gene: 308535192

Centisome position: 19.85

GC content: 60.1

Gene sequence:

>1188_bases
GTGCAATTCGAGTATTACAATCCAACCCGTTTAATCTTTGCTGCCGGGGCGCTCGCACGTCTAGGAGAGATCGCCGGCCG
GCATGGCAAACGCGCCCTGCTGGTTACCGGCGGCGGTAGTGTCAAGCGCAACGGTGTCTTTGATCGCGCAGTCGCCAGCC
TGAAGCTTGCCGGCGTTTCAGCGGTGGAATGTTCCGGCGTCGAGCCCAATCCGCGAATCAGTACCGTCAGGCGCGGTGCG
AAAATCGCACGGGAGAACGGATGCGATGTGATCATCGCCCTGGGCGGCGGCAGCACTATGGACGCAGCGAAAGTCATGGC
TGCCGCGTTTTATTATGACGGCGATCCCTGGGATATGATCTTCCACGGCCAGCCTGATCCTTATGTCCCGACCCGTGCGC
TGCCCGTCATCACGGTGCCTACCTTGGCGGCCACCGGCTCCGAGATGAATATGGGTGCGGTCATTTCGAACGAGGAGACC
AGGGAAAAGTCCTTTGTCAGCACAGAATGCCTGTATCCAGCGGTTGCCCTCGTTGACCCCGAACTCACCATGAGTGTGCC
TAAGGATCAGACTGCCTATGGGATCTGCGACCTGATCACCCATGTGACCGAAGGTTACTTCAACGGTGTCGACGGCACCC
CCATTCAGGACCGGTTCGCCGAAGGCGTCATCCTCACAGCCATGCAGTGGGGTCCCAAAGCTATTGCCGACGGGAGTGAT
CTGGAAGCGCGGGCCCAGGTTCAATGGGCTTCCATTGTCGCCCTCAACGGCTGGGTTAACGCAGGGACCAACGGCGGGTT
CCCCGTGCACATGATCGAGCATACCCTGTCCGCCTATCACGACATCACCCACGGGGCAGGTCTGGCCGTGGTCAATCCTT
CCTGGATGCGTTTTGCCGCGAGACACAGGCCGGAAAAGTTCGTGCAGTTTGCCGAACGCATCTTCGGCCTGCAGCCGGCG
AGACCGGATGACCTTGCGTGTGCCATGGAAGGAATCGACCGCTTTGAAGCGTTTCTGCGCTCCACCGGCTGCCCGACCCG
CCTTTCAGAGCTGAAGATTGGGGATGCTCTGCTGGCAGAGTATGCCAGGGAAACGGTCCGTATCATTCATGATGACCAGG
GGCGTTTGCCGGGGTGGCCCCCGATGAGCGAGTCGGACATTGTCGATGTGCTGCAGTCGGCGCTGTGA

Upstream 100 bases:

>100_bases
CCCGTAGGATCATTCTACCGGTCTCTCCGATGTGGGGGGTACTATGCCTACAGGATTCGAAAAAGCTTCTAAACCAAACA
ATTGTCCCACGGAGGTTCAC

Downstream 100 bases:

>100_bases
TATTTCCCGAGGAATTGTTGTCGGACGGCCATGAGGATGCAGTTATTGCCGGGTGGCGGATGTGGAGTGCAGTTGGCTCG
ATGTCGCTGTGTGTGGCAAT

Product: butanol dehydrogenase, NAD-dependent

Products: NA

Alternate protein names: BDH I [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQFEYYNPTRLIFAAGALARLGEIAGRHGKRALLVTGGGSVKRNGVFDRAVASLKLAGVSAVECSGVEPNPRISTVRRGA
KIARENGCDVIIALGGGSTMDAAKVMAAAFYYDGDPWDMIFHGQPDPYVPTRALPVITVPTLAATGSEMNMGAVISNEET
REKSFVSTECLYPAVALVDPELTMSVPKDQTAYGICDLITHVTEGYFNGVDGTPIQDRFAEGVILTAMQWGPKAIADGSD
LEARAQVQWASIVALNGWVNAGTNGGFPVHMIEHTLSAYHDITHGAGLAVVNPSWMRFAARHRPEKFVQFAERIFGLQPA
RPDDLACAMEGIDRFEAFLRSTGCPTRLSELKIGDALLAEYARETVRIIHDDQGRLPGWPPMSESDIVDVLQSAL

Sequences:

>Translated_395_residues
MQFEYYNPTRLIFAAGALARLGEIAGRHGKRALLVTGGGSVKRNGVFDRAVASLKLAGVSAVECSGVEPNPRISTVRRGA
KIARENGCDVIIALGGGSTMDAAKVMAAAFYYDGDPWDMIFHGQPDPYVPTRALPVITVPTLAATGSEMNMGAVISNEET
REKSFVSTECLYPAVALVDPELTMSVPKDQTAYGICDLITHVTEGYFNGVDGTPIQDRFAEGVILTAMQWGPKAIADGSD
LEARAQVQWASIVALNGWVNAGTNGGFPVHMIEHTLSAYHDITHGAGLAVVNPSWMRFAARHRPEKFVQFAERIFGLQPA
RPDDLACAMEGIDRFEAFLRSTGCPTRLSELKIGDALLAEYARETVRIIHDDQGRLPGWPPMSESDIVDVLQSAL
>Mature_395_residues
MQFEYYNPTRLIFAAGALARLGEIAGRHGKRALLVTGGGSVKRNGVFDRAVASLKLAGVSAVECSGVEPNPRISTVRRGA
KIARENGCDVIIALGGGSTMDAAKVMAAAFYYDGDPWDMIFHGQPDPYVPTRALPVITVPTLAATGSEMNMGAVISNEET
REKSFVSTECLYPAVALVDPELTMSVPKDQTAYGICDLITHVTEGYFNGVDGTPIQDRFAEGVILTAMQWGPKAIADGSD
LEARAQVQWASIVALNGWVNAGTNGGFPVHMIEHTLSAYHDITHGAGLAVVNPSWMRFAARHRPEKFVQFAERIFGLQPA
RPDDLACAMEGIDRFEAFLRSTGCPTRLSELKIGDALLAEYARETVRIIHDDQGRLPGWPPMSESDIVDVLQSAL

Specific function: Unknown

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=304, Percent_Identity=25.9868421052632, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789386, Length=351, Percent_Identity=37.3219373219373, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI1787493, Length=420, Percent_Identity=30, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI48994951, Length=363, Percent_Identity=26.1707988980716, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082107, Length=336, Percent_Identity=29.7619047619048, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789163, Length=354, Percent_Identity=25.1412429378531, Blast_Score=102, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17537053, Length=377, Percent_Identity=25.1989389920424, Blast_Score=99, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321181, Length=364, Percent_Identity=29.1208791208791, Blast_Score=112, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24657991, Length=380, Percent_Identity=24.2105263157895, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42607; Mature: 42607

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFEYYNPTRLIFAAGALARLGEIAGRHGKRALLVTGGGSVKRNGVFDRAVASLKLAGVS
CCCEEECCCEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCC
AVECSGVEPNPRISTVRRGAKIARENGCDVIIALGGGSTMDAAKVMAAAFYYDGDPWDMI
EEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHEECCCCEEEE
FHGQPDPYVPTRALPVITVPTLAATGSEMNMGAVISNEETREKSFVSTECLYPAVALVDP
ECCCCCCCCCCCCCCEEEECCCEECCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEECC
ELTMSVPKDQTAYGICDLITHVTEGYFNGVDGTPIQDRFAEGVILTAMQWGPKAIADGSD
CCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCCC
LEARAQVQWASIVALNGWVNAGTNGGFPVHMIEHTLSAYHDITHGAGLAVVNPSWMRFAA
CCHHHEEEEEEEEEEECEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHH
RHRPEKFVQFAERIFGLQPARPDDLACAMEGIDRFEAFLRSTGCPTRLSELKIGDALLAE
HCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
YARETVRIIHDDQGRLPGWPPMSESDIVDVLQSAL
HHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MQFEYYNPTRLIFAAGALARLGEIAGRHGKRALLVTGGGSVKRNGVFDRAVASLKLAGVS
CCCEEECCCEEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCC
AVECSGVEPNPRISTVRRGAKIARENGCDVIIALGGGSTMDAAKVMAAAFYYDGDPWDMI
EEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHEECCCCEEEE
FHGQPDPYVPTRALPVITVPTLAATGSEMNMGAVISNEETREKSFVSTECLYPAVALVDP
ECCCCCCCCCCCCCCEEEECCCEECCCCCCCCEEECCCHHHHHHHHHHHHHCCCCEEECC
ELTMSVPKDQTAYGICDLITHVTEGYFNGVDGTPIQDRFAEGVILTAMQWGPKAIADGSD
CCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCCC
LEARAQVQWASIVALNGWVNAGTNGGFPVHMIEHTLSAYHDITHGAGLAVVNPSWMRFAA
CCHHHEEEEEEEEEEECEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHH
RHRPEKFVQFAERIFGLQPARPDDLACAMEGIDRFEAFLRSTGCPTRLSELKIGDALLAE
HCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
YARETVRIIHDDQGRLPGWPPMSESDIVDVLQSAL
HHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1385386; 11466286; 1809209 [H]