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The map label for this gene is opdE [H]

Identifier: 308535192

GI number: 308535192

Start: 917165

End: 918403

Strand: Direct

Name: opdE [H]

Synonym: NA

Alternate gene names: 308535192

Gene position: 917165-918403 (Clockwise)

Preceding gene: 197117175

Following gene: 197117177

Centisome position: 19.87

GC content: 58.27

Gene sequence:

>1239_bases
GTGATATTTCCCGAGGAATTGTTGTCGGACGGCCATGAGGATGCAGTTATTGCCGGGTGGCGGATGTGGAGTGCAGTTGG
CTCGATGTCGCTGTGTGTGGCAATGCTTATCGCTTCGGAGTTCATGCCGGTCAGCCTGCTGACACCGATTGCAGCCGATC
TGGGTGCGACTGCCGGAATGGCGGGCCAAGCCATCTCCATTTCGGGTCTCTTCGCAGTGGTAACCAGCTTGTTCATCGCA
ACCATCGCAGGGCGCATAGATCGCCGCCATTTGCTGATGGGGTTGACGGGTCTGATGTTGGCTTCGTTGATACTGATCGC
GGAGGCCTCAAGCTTTGGCATGCTGATGATTGCCCGCGCGGTTCTGGGTATGGTGGTCGGTGGATTTTGGGCGCTGGCCA
CGGCAACGATTATGCGCCTGGTTCCGAAGGACGCAGTCCCCAAGACGTTGGGGGCCATGTACACGGGCAACGCTTTAGCC
ACCACCTTTGCCGCGCCCATCGGCAGCTACCTCGGAGGCATCATCGGCTGGCGCGGCGTCTTCTGGGCGCTTGTGCCCAT
AGTAGTGCTGAATCTGATCTGGCAATGGATAAGCCTGCCGTCCATGCCTCCACAAACCGCTAACCCTGTTGGTAAAGTCT
TTGGCCTGTTGCAACGACGCAATGTCGCCTTCGCCATGGCGGGCGTAATGCTCTCCTTTGCCGGCGCCTTCGGCGTATTC
ACCTATATGCGGCCCTTTCTTGAAGCTTACACACGGGTAAGCGTGCCCCAACTGTCTCTGCTCTTGCTTGCGATGGGAGG
GGCTGGATTTGTCGGCACATACGGAGCCACAGCACTGCTTGAGCGTCATCTTTACTCGTTGCTCAGGTTGTTACCCCTGG
CACTAGGTGTGGTGACGATTGGCCTGCTGTCGGTTGGACATGTTCTATGGGGAGTCGCGGCCATGCTGATTGCCTGGGGG
ACACTGAACTCGGCCATTCCGGTGTCGTGGTCCGCCTGGCTGGCTAAAGGTATCAGCGACGAACCGGAAAGCGGCGGCGG
GTTGATCGTGGCAGCGATTCAGCTCTCGATCATGCTGGGGGCAGCGTTCGGCGGTTTGCTCCTGGACCATATTTCGATTG
CGGCAACGCTGATCGGTGGCGCAGTTCTTCTCGTTCTTGCGTCGCTGATAATCGGTAATGGCGACCGCATCAGATCAAGC
GTAGGAGCAAACGGGCAGGCGGTTAATCCTCTCCGTTAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:
NA

Sequences:

>Translated_412_residues
MIFPEELLSDGHEDAVIAGWRMWSAVGSMSLCVAMLIASEFMPVSLLTPIAADLGATAGMAGQAISISGLFAVVTSLFIA
TIAGRIDRRHLLMGLTGLMLASLILIAEASSFGMLMIARAVLGMVVGGFWALATATIMRLVPKDAVPKTLGAMYTGNALA
TTFAAPIGSYLGGIIGWRGVFWALVPIVVLNLIWQWISLPSMPPQTANPVGKVFGLLQRRNVAFAMAGVMLSFAGAFGVF
TYMRPFLEAYTRVSVPQLSLLLLAMGGAGFVGTYGATALLERHLYSLLRLLPLALGVVTIGLLSVGHVLWGVAAMLIAWG
TLNSAIPVSWSAWLAKGISDEPESGGGLIVAAIQLSIMLGAAFGGLLLDHISIAATLIGGAVLLVLASLIIGNGDRIRSS
VGANGQAVNPLR
>Mature_412_residues
MIFPEELLSDGHEDAVIAGWRMWSAVGSMSLCVAMLIASEFMPVSLLTPIAADLGATAGMAGQAISISGLFAVVTSLFIA
TIAGRIDRRHLLMGLTGLMLASLILIAEASSFGMLMIARAVLGMVVGGFWALATATIMRLVPKDAVPKTLGAMYTGNALA
TTFAAPIGSYLGGIIGWRGVFWALVPIVVLNLIWQWISLPSMPPQTANPVGKVFGLLQRRNVAFAMAGVMLSFAGAFGVF
TYMRPFLEAYTRVSVPQLSLLLLAMGGAGFVGTYGATALLERHLYSLLRLLPLALGVVTIGLLSVGHVLWGVAAMLIAWG
TLNSAIPVSWSAWLAKGISDEPESGGGLIVAAIQLSIMLGAAFGGLLLDHISIAATLIGGAVLLVLASLIIGNGDRIRSS
VGANGQAVNPLR

Specific function: Regulates the expression of oprD which encodes the imipenem-specific porin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ywfA [H]

Homologues:

Organism=Escherichia coli, GI145693198, Length=383, Percent_Identity=39.4255874673629, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1787947, Length=305, Percent_Identity=25.5737704918033, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786595, Length=230, Percent_Identity=25.2173913043478, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787808, Length=162, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42870; Mature: 42870

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1427017; 10984043 [H]