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The map label for this gene is virA [H]

Identifier: 197117068

GI number: 197117068

Start: 794958

End: 797270

Strand: Direct

Name: virA [H]

Synonym: Gbem_0672

Alternate gene names: 197117068

Gene position: 794958-797270 (Clockwise)

Preceding gene: 197117067

Following gene: 197117069

Centisome position: 17.22

GC content: 64.38

Gene sequence:

>2313_bases
ATGAGCCATGCAGAGAGCAGGAGAAGATTGACCCCATTCAACATCACCATGGCCTATGCCACCTTCGGTGTCGCATGGGG
CGCTGCGTCCTGTCTGTTCCCCGCGGTCCTAGCACATCAATCCTTCATGTACGACGCAGTCGAAACAGTGAACCATGCCT
TATTCGTATTCGGCACGGCCTGCCTTTTGTACCTGCTGATCAAGCGCAGCGACGGCGAGGCGTCCCGCGGCCGCGAGTCC
CTCTCCAGGGTGAACCGGGCGCTCAAGACCTTCAGCGGCTGCAACCAGGCGCTGGTGCGCGCCAGCGGCGAGCTCCAGCT
GATGCAGGAGATCTGCCGCACCATCGTCGAGGTGGGGGGGTACCGGCTCGCCTGGGTAGGGGTAGCCGAGCACGACGCCT
GGAAGACGGTCCGCCCGGTGGCCCAGTGGGGAGACCGCGACGGTTACCTCACCGACCTGGATCTCAGTTGGGGGGACATA
GACCACGGCCGTGGGCCGACCGGGACGGCGATCAGGACCTGTACCACCCAGATCGTGCAGAACATCAAATACGACCCCTC
TTGGGCGCTCTGGCGGGAGGCCGGGGTGCAGCACGGCTTCGCCTCCTCCATCTCGCTGCCGCTCGTCGGGAGGGACCGCG
CCATGGGGGCGCTGGTGATCTTCGCCGCGGAAAAAAGGGCCTTCGGCAAGGAGGAGGTGAAGCTTCTCGAAGAACTGTCG
GCAGACCTTTCTTACGGCATAGAAGCGCTCCGGATGGACGCCGAGCGCAAAAAGGCGGAGAAGGAGATCCTCCTCCTCGC
CTCGGTGCTAGAGCAGTCGATGGAGGGGTTGCTCCTTTTGGACAGCGACGGCACCGTGAAGTACGTGAACCCCGCCATCG
AGATCATCACCGGCCTCGATGCGGCGGACATCGTCGGGCACGACCTCGCCACGCTCGGCGCCGACGAGGAGAACGGCGGG
TTTTACCGTTACCTCTTGGACGCGCTGGAAAAAGGGGAATGCCGGACCGGGCACTTCATCCATACCGACGACGACGGCGA
CTTCTACGAGATAGACGCGACCCTTTGGTCCATCGCGGACAACATGGGCGCGGTCAGCAATTACGCGGTGCTGATAAAGG
ACGTGACCCACGAGGTGAAGCTGGAGCGGCAACTGCGCCAGGCCCAGCGGATGGAGGCCATCGCCACGCTCGCCGGGGGG
ATCGCCCACGACTTCAACAACAACCTGGCCTCGATCATCACCTGCACCGAGATGGCGCGGGACGACGTCCCTCCGGAGAG
CCCGCTGCGCGAGTTGCTGGACGTGGTGCTGAAATCGAGCTACCGCGGCAGGAAACTGGTGAAGCAGATCCTCACCTTCT
GCTGTCAGGGGGAGCAGGAGAGGCAGCCGGTGCAGATCGAGCCGATCGTCACCGAGTGCCTGAACCTGATGCGCGCCTCG
CTCTCCTCCTCCATCAGCATCAGGACCGAGATGGGGGAGAACCTCGGCCTGATCATGGCGGACCCGACCCAGATCCACCA
GATCATCATGAACCTGATCGCCAACGCCTCCCATGCCATGCGGCACAAGGGTGGGATGCTGGACGTCGCCGTCGAGAACG
TGGGGCTCGACACCGCTGCGGTCGCCGGGTTCCCCGACCTCCCCTCGGGGCGCTACCTGAAGCTGACCGTGAAGGATACC
GGGCACGGCATGGACCAAAAGACCATGGAGCGCATCTTCGATCCCTTCTTCACCACCAAGAGCCATTCGGAGGGGACGGG
GCTCGGCCTTTCCGTGGTGCACGGCATCGTGAGAAACCACGGCGGTGCCATCTCGGTGAGCAGCAAGCCCGGCGGCGGCG
CCACCTTCGAGGTCTACCTCCCCCGCATCGACCAGTCCGGGACGGCACCGGGGGTGGTGGGGGAGCGGGCCGATCTGTCC
GGGAGCGGAAGCATCCTCTTCGTGGACGACGAGGAGGACGTGGTCTTTGGCTGCAAAAAAATGCTGGAGCGGCTGGGGTA
CCAGGTGACTACCGGAGCCGACGGCTTGCAGGCACTGGAACTGTTCCGGGGGAACCCGGAGGGGTTCGACCTGGTGGTCA
CCGACCAGACCATGCCGCGCATGACCGGGACCGAGCTCTCGCGGGAACTCTTGCAGATACGCCCCGACATCCCGGTCATC
CTCTGCACCGGGCTTGGTGCCGCGGCGGAGAAAGCGCAGTTGAAAGAGGAGGCCGAACAGGTTGGGATACGCGAGCTGGC
GCTGAAGCCCTTGGACCGTGAGGAGTTCGCGTCGACGATACGGCGGGTGCTGGCGGGAAGGGAGCAGGAGTGA

Upstream 100 bases:

>100_bases
TGACAGAAAAACTCCCCTTCAATAGCAAGATTCGATCTCTGTGTTACACTGGGTTCCATTGTTCTTCTCTAACGGTTGTT
GCCCAGACAGAGGTCAACCT

Downstream 100 bases:

>100_bases
AGAGGCCATGGCGAAGATTCTGATTGTCGACGATGAAGAGACCGTTTGCGAGTCGATGGCGCTGATAGGAAGGCGCAGCG
GCCATGAAACGAGCTGCGCC

Product: GAF/PAS domain-containing sensor histidine kinase response regulator

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 770; Mature: 769

Protein sequence:

>770_residues
MSHAESRRRLTPFNITMAYATFGVAWGAASCLFPAVLAHQSFMYDAVETVNHALFVFGTACLLYLLIKRSDGEASRGRES
LSRVNRALKTFSGCNQALVRASGELQLMQEICRTIVEVGGYRLAWVGVAEHDAWKTVRPVAQWGDRDGYLTDLDLSWGDI
DHGRGPTGTAIRTCTTQIVQNIKYDPSWALWREAGVQHGFASSISLPLVGRDRAMGALVIFAAEKRAFGKEEVKLLEELS
ADLSYGIEALRMDAERKKAEKEILLLASVLEQSMEGLLLLDSDGTVKYVNPAIEIITGLDAADIVGHDLATLGADEENGG
FYRYLLDALEKGECRTGHFIHTDDDGDFYEIDATLWSIADNMGAVSNYAVLIKDVTHEVKLERQLRQAQRMEAIATLAGG
IAHDFNNNLASIITCTEMARDDVPPESPLRELLDVVLKSSYRGRKLVKQILTFCCQGEQERQPVQIEPIVTECLNLMRAS
LSSSISIRTEMGENLGLIMADPTQIHQIIMNLIANASHAMRHKGGMLDVAVENVGLDTAAVAGFPDLPSGRYLKLTVKDT
GHGMDQKTMERIFDPFFTTKSHSEGTGLGLSVVHGIVRNHGGAISVSSKPGGGATFEVYLPRIDQSGTAPGVVGERADLS
GSGSILFVDDEEDVVFGCKKMLERLGYQVTTGADGLQALELFRGNPEGFDLVVTDQTMPRMTGTELSRELLQIRPDIPVI
LCTGLGAAAEKAQLKEEAEQVGIRELALKPLDREEFASTIRRVLAGREQE

Sequences:

>Translated_770_residues
MSHAESRRRLTPFNITMAYATFGVAWGAASCLFPAVLAHQSFMYDAVETVNHALFVFGTACLLYLLIKRSDGEASRGRES
LSRVNRALKTFSGCNQALVRASGELQLMQEICRTIVEVGGYRLAWVGVAEHDAWKTVRPVAQWGDRDGYLTDLDLSWGDI
DHGRGPTGTAIRTCTTQIVQNIKYDPSWALWREAGVQHGFASSISLPLVGRDRAMGALVIFAAEKRAFGKEEVKLLEELS
ADLSYGIEALRMDAERKKAEKEILLLASVLEQSMEGLLLLDSDGTVKYVNPAIEIITGLDAADIVGHDLATLGADEENGG
FYRYLLDALEKGECRTGHFIHTDDDGDFYEIDATLWSIADNMGAVSNYAVLIKDVTHEVKLERQLRQAQRMEAIATLAGG
IAHDFNNNLASIITCTEMARDDVPPESPLRELLDVVLKSSYRGRKLVKQILTFCCQGEQERQPVQIEPIVTECLNLMRAS
LSSSISIRTEMGENLGLIMADPTQIHQIIMNLIANASHAMRHKGGMLDVAVENVGLDTAAVAGFPDLPSGRYLKLTVKDT
GHGMDQKTMERIFDPFFTTKSHSEGTGLGLSVVHGIVRNHGGAISVSSKPGGGATFEVYLPRIDQSGTAPGVVGERADLS
GSGSILFVDDEEDVVFGCKKMLERLGYQVTTGADGLQALELFRGNPEGFDLVVTDQTMPRMTGTELSRELLQIRPDIPVI
LCTGLGAAAEKAQLKEEAEQVGIRELALKPLDREEFASTIRRVLAGREQE
>Mature_769_residues
SHAESRRRLTPFNITMAYATFGVAWGAASCLFPAVLAHQSFMYDAVETVNHALFVFGTACLLYLLIKRSDGEASRGRESL
SRVNRALKTFSGCNQALVRASGELQLMQEICRTIVEVGGYRLAWVGVAEHDAWKTVRPVAQWGDRDGYLTDLDLSWGDID
HGRGPTGTAIRTCTTQIVQNIKYDPSWALWREAGVQHGFASSISLPLVGRDRAMGALVIFAAEKRAFGKEEVKLLEELSA
DLSYGIEALRMDAERKKAEKEILLLASVLEQSMEGLLLLDSDGTVKYVNPAIEIITGLDAADIVGHDLATLGADEENGGF
YRYLLDALEKGECRTGHFIHTDDDGDFYEIDATLWSIADNMGAVSNYAVLIKDVTHEVKLERQLRQAQRMEAIATLAGGI
AHDFNNNLASIITCTEMARDDVPPESPLRELLDVVLKSSYRGRKLVKQILTFCCQGEQERQPVQIEPIVTECLNLMRASL
SSSISIRTEMGENLGLIMADPTQIHQIIMNLIANASHAMRHKGGMLDVAVENVGLDTAAVAGFPDLPSGRYLKLTVKDTG
HGMDQKTMERIFDPFFTTKSHSEGTGLGLSVVHGIVRNHGGAISVSSKPGGGATFEVYLPRIDQSGTAPGVVGERADLSG
SGSILFVDDEEDVVFGCKKMLERLGYQVTTGADGLQALELFRGNPEGFDLVVTDQTMPRMTGTELSRELLQIRPDIPVIL
CTGLGAAAEKAQLKEEAEQVGIRELALKPLDREEFASTIRRVLAGREQE

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=355, Percent_Identity=29.8591549295775, Blast_Score=152, Evalue=6e-38,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=31.8181818181818, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI48994928, Length=328, Percent_Identity=28.3536585365854, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788713, Length=277, Percent_Identity=29.9638989169675, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI87081816, Length=298, Percent_Identity=26.8456375838926, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1790300, Length=361, Percent_Identity=24.0997229916898, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI145693157, Length=355, Percent_Identity=26.4788732394366, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786912, Length=276, Percent_Identity=26.4492753623188, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1789149, Length=256, Percent_Identity=24.21875, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84177; Mature: 84046

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHAESRRRLTPFNITMAYATFGVAWGAASCLFPAVLAHQSFMYDAVETVNHALFVFGTA
CCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CLLYLLIKRSDGEASRGRESLSRVNRALKTFSGCNQALVRASGELQLMQEICRTIVEVGG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
YRLAWVGVAEHDAWKTVRPVAQWGDRDGYLTDLDLSWGDIDHGRGPTGTAIRTCTTQIVQ
CEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
NIKYDPSWALWREAGVQHGFASSISLPLVGRDRAMGALVIFAAEKRAFGKEEVKLLEELS
HCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHCCCHHHHHHHHHHH
ADLSYGIEALRMDAERKKAEKEILLLASVLEQSMEGLLLLDSDGTVKYVNPAIEIITGLD
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECHHHHHHHCCC
AADIVGHDLATLGADEENGGFYRYLLDALEKGECRTGHFIHTDDDGDFYEIDATLWSIAD
HHHHHCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEHHHHHHHHH
NMGAVSNYAVLIKDVTHEVKLERQLRQAQRMEAIATLAGGIAHDFNNNLASIITCTEMAR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DDVPPESPLRELLDVVLKSSYRGRKLVKQILTFCCQGEQERQPVQIEPIVTECLNLMRAS
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHH
LSSSISIRTEMGENLGLIMADPTQIHQIIMNLIANASHAMRHKGGMLDVAVENVGLDTAA
HHCCEEEEECCCCCCCEEEECHHHHHHHHHHHHHCCHHHHHHCCCEEEEEEHHCCCCHHH
VAGFPDLPSGRYLKLTVKDTGHGMDQKTMERIFDPFFTTKSHSEGTGLGLSVVHGIVRNH
HCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCC
GGAISVSSKPGGGATFEVYLPRIDQSGTAPGVVGERADLSGSGSILFVDDEEDVVFGCKK
CCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHH
MLERLGYQVTTGADGLQALELFRGNPEGFDLVVTDQTMPRMTGTELSRELLQIRPDIPVI
HHHHCCCEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEE
LCTGLGAAAEKAQLKEEAEQVGIRELALKPLDREEFASTIRRVLAGREQE
EECCCCCHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SHAESRRRLTPFNITMAYATFGVAWGAASCLFPAVLAHQSFMYDAVETVNHALFVFGTA
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CLLYLLIKRSDGEASRGRESLSRVNRALKTFSGCNQALVRASGELQLMQEICRTIVEVGG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
YRLAWVGVAEHDAWKTVRPVAQWGDRDGYLTDLDLSWGDIDHGRGPTGTAIRTCTTQIVQ
CEEEEEEECCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
NIKYDPSWALWREAGVQHGFASSISLPLVGRDRAMGALVIFAAEKRAFGKEEVKLLEELS
HCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHCCCHHHHHHHHHHH
ADLSYGIEALRMDAERKKAEKEILLLASVLEQSMEGLLLLDSDGTVKYVNPAIEIITGLD
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECHHHHHHHCCC
AADIVGHDLATLGADEENGGFYRYLLDALEKGECRTGHFIHTDDDGDFYEIDATLWSIAD
HHHHHCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEHHHHHHHHH
NMGAVSNYAVLIKDVTHEVKLERQLRQAQRMEAIATLAGGIAHDFNNNLASIITCTEMAR
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DDVPPESPLRELLDVVLKSSYRGRKLVKQILTFCCQGEQERQPVQIEPIVTECLNLMRAS
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHH
LSSSISIRTEMGENLGLIMADPTQIHQIIMNLIANASHAMRHKGGMLDVAVENVGLDTAA
HHCCEEEEECCCCCCCEEEECHHHHHHHHHHHHHCCHHHHHHCCCEEEEEEHHCCCCHHH
VAGFPDLPSGRYLKLTVKDTGHGMDQKTMERIFDPFFTTKSHSEGTGLGLSVVHGIVRNH
HCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCC
GGAISVSSKPGGGATFEVYLPRIDQSGTAPGVVGERADLSGSGSILFVDDEEDVVFGCKK
CCEEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHH
MLERLGYQVTTGADGLQALELFRGNPEGFDLVVTDQTMPRMTGTELSRELLQIRPDIPVI
HHHHCCCEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEE
LCTGLGAAAEKAQLKEEAEQVGIRELALKPLDREEFASTIRRVLAGREQE
EECCCCCHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2796735; 2194232; 11743193; 11743194 [H]