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The map label for this gene is ycgM [H]

Identifier: 197117047

GI number: 197117047

Start: 773081

End: 773737

Strand: Reverse

Name: ycgM [H]

Synonym: Gbem_0650

Alternate gene names: 197117047

Gene position: 773737-773081 (Counterclockwise)

Preceding gene: 197117048

Following gene: 197117037

Centisome position: 16.77

GC content: 63.93

Gene sequence:

>657_bases
ATGAAGACGGCAAGGGTCAAGGGAGAAGCAAAAGAGTATCGGATCGGCAAGATCCTCTGCATCGGGAGGAACTACGCGGA
CCACATCAAGGAACTGGGGAACGAGACCCCGGAACGCCCGGTGATCTTCATGAAGCCGGCCTCCAGCGTCATCGGCGAAG
GGGAAGAGATCGTGATCCCCCCCTACTCCAGCGACTGCCACCACGAGGCGGAGCTGGCGCTTTTGATCGGCACCGGCGGG
AGCGATATCCCTCCCGCTGAGGCGTTAGGCCACCTGGCCGGGTACGGCGTAGCCATCGACCTGACCCTCAGGGACGTGCA
GGCGGAGCAGAAGAAAAAGGGGCTCCCTTGGGAGATCGCCAAGGGGTTCGACACCGCCTGCCCCCTCTCCGACTTCGTGC
CGGCAGGTGCTGTGGCCGACCCGCAGGCGCTCACCATCACGCTCAGCGTCAACGGGGTCAAGCGGCAGGACGGCTCGACC
GGCCTCATGATCCACCGCATCCCGGAGCTCATCTCCTACCTCTCCTCCATCTTCACCCTGGAGCCGGGCGACCTGGTGCT
GACCGGCACACCGGCCGGCGTCGGCCCGATAAAAAGCGGGGACAGCGTCGTCGCCGAAATTACCCAAGTGGGGAGACTGC
AGGTCTCGGTCAAATAA

Upstream 100 bases:

>100_bases
ACGCGGTGGTGAACGAGCTGAAAAGGCGCGGCAGCTGGCAGGGGTGCCGGGTGGGTTGCGAGATGCGCGCGGTGAACGGC
TAGCTAAAGCGAGGAGAAAC

Downstream 100 bases:

>100_bases
ATAAAAAGGAGAATCGAATGAAAAACGAACAAGAGTGCCCCGAATGCCAGGGGCTCATGGTGCTGATACCCGGTTGAGGC
GGCCTCTTCTGGCGGTGCCA

Product: fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MKTARVKGEAKEYRIGKILCIGRNYADHIKELGNETPERPVIFMKPASSVIGEGEEIVIPPYSSDCHHEAELALLIGTGG
SDIPPAEALGHLAGYGVAIDLTLRDVQAEQKKKGLPWEIAKGFDTACPLSDFVPAGAVADPQALTITLSVNGVKRQDGST
GLMIHRIPELISYLSSIFTLEPGDLVLTGTPAGVGPIKSGDSVVAEITQVGRLQVSVK

Sequences:

>Translated_218_residues
MKTARVKGEAKEYRIGKILCIGRNYADHIKELGNETPERPVIFMKPASSVIGEGEEIVIPPYSSDCHHEAELALLIGTGG
SDIPPAEALGHLAGYGVAIDLTLRDVQAEQKKKGLPWEIAKGFDTACPLSDFVPAGAVADPQALTITLSVNGVKRQDGST
GLMIHRIPELISYLSSIFTLEPGDLVLTGTPAGVGPIKSGDSVVAEITQVGRLQVSVK
>Mature_218_residues
MKTARVKGEAKEYRIGKILCIGRNYADHIKELGNETPERPVIFMKPASSVIGEGEEIVIPPYSSDCHHEAELALLIGTGG
SDIPPAEALGHLAGYGVAIDLTLRDVQAEQKKKGLPWEIAKGFDTACPLSDFVPAGAVADPQALTITLSVNGVKRQDGST
GLMIHRIPELISYLSSIFTLEPGDLVLTGTPAGVGPIKSGDSVVAEITQVGRLQVSVK

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=199, Percent_Identity=47.2361809045226, Blast_Score=203, Evalue=7e-53,
Organism=Homo sapiens, GI215422413, Length=199, Percent_Identity=47.2361809045226, Blast_Score=203, Evalue=8e-53,
Organism=Homo sapiens, GI66348062, Length=199, Percent_Identity=47.2361809045226, Blast_Score=203, Evalue=9e-53,
Organism=Homo sapiens, GI156231349, Length=206, Percent_Identity=42.2330097087379, Blast_Score=164, Evalue=6e-41,
Organism=Homo sapiens, GI40786394, Length=203, Percent_Identity=41.3793103448276, Blast_Score=158, Evalue=3e-39,
Organism=Escherichia coli, GI1787428, Length=198, Percent_Identity=51.010101010101, Blast_Score=209, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI17557057, Length=187, Percent_Identity=46.524064171123, Blast_Score=187, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6324161, Length=225, Percent_Identity=42.2222222222222, Blast_Score=174, Evalue=8e-45,
Organism=Drosophila melanogaster, GI28571789, Length=202, Percent_Identity=37.6237623762376, Blast_Score=158, Evalue=3e-39,
Organism=Drosophila melanogaster, GI28572127, Length=206, Percent_Identity=36.8932038834951, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24663695, Length=209, Percent_Identity=33.4928229665072, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 23064; Mature: 23064

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTARVKGEAKEYRIGKILCIGRNYADHIKELGNETPERPVIFMKPASSVIGEGEEIVIP
CCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHCCCCCCCCEEEECCCHHHHCCCCEEEEC
PYSSDCHHEAELALLIGTGGSDIPPAEALGHLAGYGVAIDLTLRDVQAEQKKKGLPWEIA
CCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEEEHHHHHHHHCCCCEEHH
KGFDTACPLSDFVPAGAVADPQALTITLSVNGVKRQDGSTGLMIHRIPELISYLSSIFTL
CCCCCCCCHHHCCCCCCCCCCCEEEEEEEECCEECCCCCCCEEHHHHHHHHHHHHHHHEE
EPGDLVLTGTPAGVGPIKSGDSVVAEITQVGRLQVSVK
CCCCEEEECCCCCCCCCCCCCHHHHHHHHCCEEEEEEC
>Mature Secondary Structure
MKTARVKGEAKEYRIGKILCIGRNYADHIKELGNETPERPVIFMKPASSVIGEGEEIVIP
CCCCCCCCCCCEEEEEEEEEECCCHHHHHHHHCCCCCCCCEEEECCCHHHHCCCCEEEEC
PYSSDCHHEAELALLIGTGGSDIPPAEALGHLAGYGVAIDLTLRDVQAEQKKKGLPWEIA
CCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEEEHHHHHHHHCCCCEEHH
KGFDTACPLSDFVPAGAVADPQALTITLSVNGVKRQDGSTGLMIHRIPELISYLSSIFTL
CCCCCCCCHHHCCCCCCCCCCCEEEEEEEECCEECCCCCCCEEHHHHHHHHHHHHHHHEE
EPGDLVLTGTPAGVGPIKSGDSVVAEITQVGRLQVSVK
CCCCEEEECCCCCCCCCCCCCHHHHHHHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]