| Definition | Geobacter bemidjiensis Bem chromosome, complete genome. |
|---|---|
| Accession | NC_011146 |
| Length | 4,615,150 |
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The map label for this gene is loN-3 [H]
Identifier: 197117001
GI number: 197117001
Start: 725069
End: 727519
Strand: Direct
Name: loN-3 [H]
Synonym: Gbem_0604
Alternate gene names: 197117001
Gene position: 725069-727519 (Clockwise)
Preceding gene: 197117000
Following gene: 197117002
Centisome position: 15.71
GC content: 63.32
Gene sequence:
>2451_bases ATGGAAAACAGGCAGGAGACCGAAGAACTTAATATACCGGATGTTCTGCCGCTGCTCCCGGTGAGGGACGTGGTTGTCTA TCCCTACATGATTCTGCCGCTTTTCGTCGGTCGGGAGATCTCCATCAGCGCCGTCGATTACGCCCTTTCCAAGGACCGCA TGATCTTCCTGGCGACCCAGAGGGACGTAGGCGACGAGGACCCGGCGCCGGAGGCGATCTACGAAGTAGGGACCGTGGCG ATGATCATGCGCATGCTGAAGCTCCCGGACGGGAGGGTGAAGATCCTGGTTCAGGGGCTCACCAAGGCGCGGATCACCGA GTACCTGGCCGAGAAGCCCTTCTATTCCGTGCGCATCGACAGGATCGTGGAGCCGGCGCTGCAGGAGAACACCCTTGAGG CGGAGGCGCTGATCCGCACCGTGAAGGAAGAACTCGGGAAGATCGTGGCGCTCGGCAAGGCCGTCTCCCCCGAGGTGATG GTCATCGTCGAGAACATGCAGGAGCCCGGCTCCCTCGCCGACCTCGTCGCCAGCAACATCGGGCTCAAGGTCGAGGAGGC GCAGGGTCTTCTCGAGGTGATCGATCCCCTGGAGCGCCTGAAGCGGGTCAACGACCTCCTGAACAAGGAGAGCGAGCTCT TGAACATGCAGGCCCGCATCCAGTCTGCCGCCAAGGAGGAGATGGGGAAAAGCCAGCGCGAGTACTACCTGCGCGAGCAG CTGCGCGCCATCCAGCAGGAGCTTGGGGAGACCGACGCGAGGAGCGAGGAGATCGCCGAGCTCAGGAAGTCGATCGAGAG CGCCAAGATGCCGCAGCCGGTGGAGAAGGAGGCCCTGAAGCAGCTGGGGCGCCTGGAGCAGATGCACCCCGACGCCGCCG AGGCCGGGATGCTGCGCACCTTTCTCGACTGGATGGTGGACATCCCCTGGGGCAAATCGACCAAGGACTCCCTGGAGATC AACCGCGCCTCCGAGATCCTCAACGAGGACCACTACTTCCTGGAAAAGGTGAAGGAGCGCATCCTCGAGTTCCTGGCGGT GAGAAAGCTCAAGAAGAAGATGAAAGGACCCATCCTCTGCTTCGTCGGACCTCCGGGTGTGGGGAAGACCTCGTTAGGGA AGTCCATCGCCCGCGCCATGGGGAGGAAGTTCGTGCGCATCTCCCTGGGCGGCGTGCGCGACGAGGCCGAGATCCGCGGC CACCGCCGCACCTACGTGGGCGCCCTTCCGGGCCGGATCATCCAGGGGCTCAAGCAGGCCGGCTCCAACAACCCGGTCTT CATGCTGGACGAGCTGGACAAGCTAGGCTCCGATTTCCGCGGCGACCCCTCCTCGGCGCTTCTGGAGGTGCTCGACCCGG AGCAGAACAACAGCTTCTCGGACCACTACATAAACCTTCCCTTCAACCTCTCCAACGTGATGTTCATCGCCACGGCGAAC CAGATGGACACCATCCCGGGGCCTTTGCGGGACAGGATGGAGGTGATCAACCTCTCCGGATACACCGAGGAGGAGAAGCT CGGCATCGCCAAACGCTATCTGGTGCCGCGGCAAGTGAAGGAAAACGGCATCACCGATGATATCGTCGCCTTCTCCGACG AGGCGCTTAGGACCGTGATCTCCAAGTACACCCGCGAGGCGGGGCTCAGGAACCTGGAGCGCGAGGTCGGCAGCATCTGC CGCAAGGTGGCCAGGAAGGTCGCGGAAGGAAAGGGCGAGCACTTCGCCATCAGTGCCGGGACCGTGGCCAAGTACCTGGG GCCGCCGAAGTTCCTGCGCGAAGAGGAGATGGAGAAGAACGAGGTAGGGGTGGTCACGGGGCTTGCCTGGACCCCGGTCG GAGGCGAGGTGCTCTTCGTCGAGGCGACCGTGATGAAAGGGAAAGGGGCGCTGACCTTGACCGGGCAGTTGGGGGACGTG ATGAAGGAATCGGTGCAGGCCGCACTCTCCTACATCCGCTCGAAGACCGCCGACTTCGACATCCCGGAAGACTTCAACTC CACCACAGACATCCACGTCCACGTTCCGGCGGGAGCCATCCCCAAGGACGGCCCCTCGGCCGGGGTAACCATGGCGACCG CCCTGGTTTCGGCGCTGACGAAGATTCCGGTGAGAAAAGAAGTCGCCATGACCGGCGAAATCACGCTGCGCGGCAAGGTG CTCCCCATCGGAGGGCTCAAGGAGAAGATCCTCGCCGCTGCGCGGCTTGGCGTCACCACCGTGGTGATCCCGGTGCAGAA CCAGAAGGACCTGGAAGACGTGCCGAAGACCATCCTCAAGAAGCTGAAGATCGTCCCCGCGTCCAACATCGACGAAGTCC TCGCCGTGGCGCTGGAGATCTATCCCCCTCGGGCGGCCTCGAAGCCCAAGCCCTCCAAGACCGAGCCCCCGAAGAGCAAG GTTGCCCGACGGGTCACCGTTCCCCCCACCGGGGTGAGGGGCAAGGCTTGA
Upstream 100 bases:
>100_bases GCACGCTACCGGCGGGGGCTGCTCACCGTGGTCATCCCGTGGTGCAAAGGGGAAAAGCCGCATATCCGGGAGATTCAGAT AGAAGAGTAAGGAGAGGTAC
Downstream 100 bases:
>100_bases GACTGGCGGAACTGGGCGAATTCGGCCTGATCGACCGCATCAAGAAAAATGTCGCCGCGTCCCCCTCGGTGCTTCTAGGC ATCGGGGATGACGCGGCGGC
Product: ATP-dependent Lon protease
Products: NA
Alternate protein names: ATP-dependent protease La [H]
Number of amino acids: Translated: 816; Mature: 816
Protein sequence:
>816_residues MENRQETEELNIPDVLPLLPVRDVVVYPYMILPLFVGREISISAVDYALSKDRMIFLATQRDVGDEDPAPEAIYEVGTVA MIMRMLKLPDGRVKILVQGLTKARITEYLAEKPFYSVRIDRIVEPALQENTLEAEALIRTVKEELGKIVALGKAVSPEVM VIVENMQEPGSLADLVASNIGLKVEEAQGLLEVIDPLERLKRVNDLLNKESELLNMQARIQSAAKEEMGKSQREYYLREQ LRAIQQELGETDARSEEIAELRKSIESAKMPQPVEKEALKQLGRLEQMHPDAAEAGMLRTFLDWMVDIPWGKSTKDSLEI NRASEILNEDHYFLEKVKERILEFLAVRKLKKKMKGPILCFVGPPGVGKTSLGKSIARAMGRKFVRISLGGVRDEAEIRG HRRTYVGALPGRIIQGLKQAGSNNPVFMLDELDKLGSDFRGDPSSALLEVLDPEQNNSFSDHYINLPFNLSNVMFIATAN QMDTIPGPLRDRMEVINLSGYTEEEKLGIAKRYLVPRQVKENGITDDIVAFSDEALRTVISKYTREAGLRNLEREVGSIC RKVARKVAEGKGEHFAISAGTVAKYLGPPKFLREEEMEKNEVGVVTGLAWTPVGGEVLFVEATVMKGKGALTLTGQLGDV MKESVQAALSYIRSKTADFDIPEDFNSTTDIHVHVPAGAIPKDGPSAGVTMATALVSALTKIPVRKEVAMTGEITLRGKV LPIGGLKEKILAAARLGVTTVVIPVQNQKDLEDVPKTILKKLKIVPASNIDEVLAVALEIYPPRAASKPKPSKTEPPKSK VARRVTVPPTGVRGKA
Sequences:
>Translated_816_residues MENRQETEELNIPDVLPLLPVRDVVVYPYMILPLFVGREISISAVDYALSKDRMIFLATQRDVGDEDPAPEAIYEVGTVA MIMRMLKLPDGRVKILVQGLTKARITEYLAEKPFYSVRIDRIVEPALQENTLEAEALIRTVKEELGKIVALGKAVSPEVM VIVENMQEPGSLADLVASNIGLKVEEAQGLLEVIDPLERLKRVNDLLNKESELLNMQARIQSAAKEEMGKSQREYYLREQ LRAIQQELGETDARSEEIAELRKSIESAKMPQPVEKEALKQLGRLEQMHPDAAEAGMLRTFLDWMVDIPWGKSTKDSLEI NRASEILNEDHYFLEKVKERILEFLAVRKLKKKMKGPILCFVGPPGVGKTSLGKSIARAMGRKFVRISLGGVRDEAEIRG HRRTYVGALPGRIIQGLKQAGSNNPVFMLDELDKLGSDFRGDPSSALLEVLDPEQNNSFSDHYINLPFNLSNVMFIATAN QMDTIPGPLRDRMEVINLSGYTEEEKLGIAKRYLVPRQVKENGITDDIVAFSDEALRTVISKYTREAGLRNLEREVGSIC RKVARKVAEGKGEHFAISAGTVAKYLGPPKFLREEEMEKNEVGVVTGLAWTPVGGEVLFVEATVMKGKGALTLTGQLGDV MKESVQAALSYIRSKTADFDIPEDFNSTTDIHVHVPAGAIPKDGPSAGVTMATALVSALTKIPVRKEVAMTGEITLRGKV LPIGGLKEKILAAARLGVTTVVIPVQNQKDLEDVPKTILKKLKIVPASNIDEVLAVALEIYPPRAASKPKPSKTEPPKSK VARRVTVPPTGVRGKA >Mature_816_residues MENRQETEELNIPDVLPLLPVRDVVVYPYMILPLFVGREISISAVDYALSKDRMIFLATQRDVGDEDPAPEAIYEVGTVA MIMRMLKLPDGRVKILVQGLTKARITEYLAEKPFYSVRIDRIVEPALQENTLEAEALIRTVKEELGKIVALGKAVSPEVM VIVENMQEPGSLADLVASNIGLKVEEAQGLLEVIDPLERLKRVNDLLNKESELLNMQARIQSAAKEEMGKSQREYYLREQ LRAIQQELGETDARSEEIAELRKSIESAKMPQPVEKEALKQLGRLEQMHPDAAEAGMLRTFLDWMVDIPWGKSTKDSLEI NRASEILNEDHYFLEKVKERILEFLAVRKLKKKMKGPILCFVGPPGVGKTSLGKSIARAMGRKFVRISLGGVRDEAEIRG HRRTYVGALPGRIIQGLKQAGSNNPVFMLDELDKLGSDFRGDPSSALLEVLDPEQNNSFSDHYINLPFNLSNVMFIATAN QMDTIPGPLRDRMEVINLSGYTEEEKLGIAKRYLVPRQVKENGITDDIVAFSDEALRTVISKYTREAGLRNLEREVGSIC RKVARKVAEGKGEHFAISAGTVAKYLGPPKFLREEEMEKNEVGVVTGLAWTPVGGEVLFVEATVMKGKGALTLTGQLGDV MKESVQAALSYIRSKTADFDIPEDFNSTTDIHVHVPAGAIPKDGPSAGVTMATALVSALTKIPVRKEVAMTGEITLRGKV LPIGGLKEKILAAARLGVTTVVIPVQNQKDLEDVPKTILKKLKIVPASNIDEVLAVALEIYPPRAASKPKPSKTEPPKSK VARRVTVPPTGVRGKA
Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced
COG id: COG0466
COG function: function code O; ATP-dependent Lon protease, bacterial type
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Lon domain [H]
Homologues:
Organism=Homo sapiens, GI31377667, Length=849, Percent_Identity=41.1071849234393, Blast_Score=599, Evalue=1e-171, Organism=Homo sapiens, GI21396489, Length=843, Percent_Identity=39.0272835112693, Blast_Score=565, Evalue=1e-161, Organism=Escherichia coli, GI1786643, Length=768, Percent_Identity=51.0416666666667, Blast_Score=801, Evalue=0.0, Organism=Caenorhabditis elegans, GI17505831, Length=710, Percent_Identity=38.3098591549296, Blast_Score=499, Evalue=1e-141, Organism=Caenorhabditis elegans, GI17556486, Length=802, Percent_Identity=36.4089775561097, Blast_Score=483, Evalue=1e-136, Organism=Saccharomyces cerevisiae, GI6319449, Length=672, Percent_Identity=42.5595238095238, Blast_Score=523, Evalue=1e-149, Organism=Drosophila melanogaster, GI221513036, Length=683, Percent_Identity=43.1918008784773, Blast_Score=563, Evalue=1e-160, Organism=Drosophila melanogaster, GI24666867, Length=683, Percent_Identity=43.1918008784773, Blast_Score=562, Evalue=1e-160,
Paralogues:
None
Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR008269 - InterPro: IPR004815 - InterPro: IPR003111 - InterPro: IPR008268 - InterPro: IPR001984 - InterPro: IPR015947 - InterPro: IPR020568 [H]
Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]
EC number: =3.4.21.53 [H]
Molecular weight: Translated: 90048; Mature: 90048
Theoretical pI: Translated: 6.92; Mature: 6.92
Prosite motif: PS01046 LON_SER
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MENRQETEELNIPDVLPLLPVRDVVVYPYMILPLFVGREISISAVDYALSKDRMIFLATQ CCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCEEEEEEC RDVGDEDPAPEAIYEVGTVAMIMRMLKLPDGRVKILVQGLTKARITEYLAEKPFYSVRID CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEHH RIVEPALQENTLEAEALIRTVKEELGKIVALGKAVSPEVMVIVENMQEPGSLADLVASNI HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHC GLKVEEAQGLLEVIDPLERLKRVNDLLNKESELLNMQARIQSAAKEEMGKSQREYYLREQ CCEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH LRAIQQELGETDARSEEIAELRKSIESAKMPQPVEKEALKQLGRLEQMHPDAAEAGMLRT HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH FLDWMVDIPWGKSTKDSLEINRASEILNEDHYFLEKVKERILEFLAVRKLKKKMKGPILC HHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE FVGPPGVGKTSLGKSIARAMGRKFVRISLGGVRDEAEIRGHRRTYVGALPGRIIQGLKQA EECCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHCCCHHHHHHCCHHHHHHHHHHC GSNNPVFMLDELDKLGSDFRGDPSSALLEVLDPEQNNSFSDHYINLPFNLSNVMFIATAN CCCCCEEEEECHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEEECC QMDTIPGPLRDRMEVINLSGYTEEEKLGIAKRYLVPRQVKENGITDDIVAFSDEALRTVI CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHCCCCHHHHHHCHHHHHHHH SKYTREAGLRNLEREVGSICRKVARKVAEGKGEHFAISAGTVAKYLGPPKFLREEEMEKN HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCHHHHHHHHCCCC EVGVVTGLAWTPVGGEVLFVEATVMKGKGALTLTGQLGDVMKESVQAALSYIRSKTADFD CCCEEEEEEECCCCCEEEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCC IPEDFNSTTDIHVHVPAGAIPKDGPSAGVTMATALVSALTKIPVRKEVAMTGEITLRGKV CCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHEEECEEEEEEEE LPIGGLKEKILAAARLGVTTVVIPVQNQKDLEDVPKTILKKLKIVPASNIDEVLAVALEI EECCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH YPPRAASKPKPSKTEPPKSKVARRVTVPPTGVRGKA CCCCCCCCCCCCCCCCCHHHHCCEECCCCCCCCCCC >Mature Secondary Structure MENRQETEELNIPDVLPLLPVRDVVVYPYMILPLFVGREISISAVDYALSKDRMIFLATQ CCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHCCCCEEEEEEC RDVGDEDPAPEAIYEVGTVAMIMRMLKLPDGRVKILVQGLTKARITEYLAEKPFYSVRID CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEHH RIVEPALQENTLEAEALIRTVKEELGKIVALGKAVSPEVMVIVENMQEPGSLADLVASNI HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHC GLKVEEAQGLLEVIDPLERLKRVNDLLNKESELLNMQARIQSAAKEEMGKSQREYYLREQ CCEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH LRAIQQELGETDARSEEIAELRKSIESAKMPQPVEKEALKQLGRLEQMHPDAAEAGMLRT HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH FLDWMVDIPWGKSTKDSLEINRASEILNEDHYFLEKVKERILEFLAVRKLKKKMKGPILC HHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE FVGPPGVGKTSLGKSIARAMGRKFVRISLGGVRDEAEIRGHRRTYVGALPGRIIQGLKQA EECCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHCCCHHHHHHCCHHHHHHHHHHC GSNNPVFMLDELDKLGSDFRGDPSSALLEVLDPEQNNSFSDHYINLPFNLSNVMFIATAN CCCCCEEEEECHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEEECC QMDTIPGPLRDRMEVINLSGYTEEEKLGIAKRYLVPRQVKENGITDDIVAFSDEALRTVI CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHCCCCHHHHHHCHHHHHHHH SKYTREAGLRNLEREVGSICRKVARKVAEGKGEHFAISAGTVAKYLGPPKFLREEEMEKN HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHCCCHHHHHHHHCCCC EVGVVTGLAWTPVGGEVLFVEATVMKGKGALTLTGQLGDVMKESVQAALSYIRSKTADFD CCCEEEEEEECCCCCEEEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCC IPEDFNSTTDIHVHVPAGAIPKDGPSAGVTMATALVSALTKIPVRKEVAMTGEITLRGKV CCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHEEECEEEEEEEE LPIGGLKEKILAAARLGVTTVVIPVQNQKDLEDVPKTILKKLKIVPASNIDEVLAVALEI EECCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH YPPRAASKPKPSKTEPPKSKVARRVTVPPTGVRGKA CCCCCCCCCCCCCCCCCHHHHCCEECCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA