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The map label for this gene is lpxH [H]

Identifier: 197116975

GI number: 197116975

Start: 699517

End: 700236

Strand: Direct

Name: lpxH [H]

Synonym: Gbem_0578

Alternate gene names: 197116975

Gene position: 699517-700236 (Clockwise)

Preceding gene: 197116970

Following gene: 197116995

Centisome position: 15.16

GC content: 61.81

Gene sequence:

>720_bases
ATGCGCAAGATCTTCATCGCCGATGCCCACCTGAAAAGACCGGAAGACGCCAACTACCGCACCCTGGTCCGGTTCCTGGA
GAACCTCCCCGCCGACACGGAGACGCTCTATCTCCTGGGGGACATCTTCGAGTTCTGGATCGGCAACCCAGAGCCTGTGT
ACGGCCACTACCGGGAGATCGTCGACTGCCTGAAGCAGGTGAGGGGGCGCGGCGTGCGCATCGTCTACTTCGAAGGGAAC
CATGATTTCCATCTGGACCGCTTCTTCGGGGAAAAACTGCAGGCAGAGGTTCATCGCGCCGGAGCGTTGCTGGAAATCGG
GGGGCAGAAGGTCTATGTGTGCCACGGCGACGAGATCAACCGCGAGGATTACCGCTATCGCGCCTTCCGGCTGCTGCTGC
ATAACCCCGTGGTAAAGGCGCTGGTCCCCATCTTCTCCAGGAGGATCGCGGACCACGCGGCGGCGGTGCTGTCGCGCCGC
TCCAGCAGCAAGCACTCCTTACGCGAAAAGCGCTGGGACTACCGGGTCATCCTCGATTCCTTCGCCCGCAACCGCTTCGC
CTCGGGGTGCGACGCGGTCATCACCGGCCATTACCACCTTCCCATGATAAAGCGGGAGCCGGGGCGCCTTTTCATCTCTT
TGGGCGACTGGATCACCCACTATTCCTACGCGCAGTGGCTGGACGGCGAGTTCACCCTGGAGAGTTACCGGGAGAACTAG

Upstream 100 bases:

>100_bases
TGTAGCCAGGGGCAAGATTAATACAAGAGAGCCGCAGGCTAAATGAGCCCTCGGCGCCTGTTCACTTTACCAAAGTTGCA
TTTTTGTATATATTGCGCGC

Downstream 100 bases:

>100_bases
CCCACCCCGAAGAGCCTCTGGTAGTTGGCCACCCGCTTCTCCAGGGTCGGGGCCGCGATGGCCCGGCAGATGTCGTCGGG
GCGGTAGCCGCGGCAGACCT

Product: metallophosphoesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MRKIFIADAHLKRPEDANYRTLVRFLENLPADTETLYLLGDIFEFWIGNPEPVYGHYREIVDCLKQVRGRGVRIVYFEGN
HDFHLDRFFGEKLQAEVHRAGALLEIGGQKVYVCHGDEINREDYRYRAFRLLLHNPVVKALVPIFSRRIADHAAAVLSRR
SSSKHSLREKRWDYRVILDSFARNRFASGCDAVITGHYHLPMIKREPGRLFISLGDWITHYSYAQWLDGEFTLESYREN

Sequences:

>Translated_239_residues
MRKIFIADAHLKRPEDANYRTLVRFLENLPADTETLYLLGDIFEFWIGNPEPVYGHYREIVDCLKQVRGRGVRIVYFEGN
HDFHLDRFFGEKLQAEVHRAGALLEIGGQKVYVCHGDEINREDYRYRAFRLLLHNPVVKALVPIFSRRIADHAAAVLSRR
SSSKHSLREKRWDYRVILDSFARNRFASGCDAVITGHYHLPMIKREPGRLFISLGDWITHYSYAQWLDGEFTLESYREN
>Mature_239_residues
MRKIFIADAHLKRPEDANYRTLVRFLENLPADTETLYLLGDIFEFWIGNPEPVYGHYREIVDCLKQVRGRGVRIVYFEGN
HDFHLDRFFGEKLQAEVHRAGALLEIGGQKVYVCHGDEINREDYRYRAFRLLLHNPVVKALVPIFSRRIADHAAAVLSRR
SSSKHSLREKRWDYRVILDSFARNRFASGCDAVITGHYHLPMIKREPGRLFISLGDWITHYSYAQWLDGEFTLESYREN

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

Organism=Escherichia coli, GI1786735, Length=233, Percent_Identity=30.9012875536481, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR010138 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: 3.6.1.-

Molecular weight: Translated: 28086; Mature: 28086

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIFIADAHLKRPEDANYRTLVRFLENLPADTETLYLLGDIFEFWIGNPEPVYGHYREI
CCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHH
VDCLKQVRGRGVRIVYFEGNHDFHLDRFFGEKLQAEVHRAGALLEIGGQKVYVCHGDEIN
HHHHHHHHCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCC
REDYRYRAFRLLLHNPVVKALVPIFSRRIADHAAAVLSRRSSSKHSLREKRWDYRVILDS
CHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHH
FARNRFASGCDAVITGHYHLPMIKREPGRLFISLGDWITHYSYAQWLDGEFTLESYREN
HHHHHHCCCCCEEEECCEECCEEEECCCEEEEEECHHHHHHHHHHHCCCCEEHHHHCCC
>Mature Secondary Structure
MRKIFIADAHLKRPEDANYRTLVRFLENLPADTETLYLLGDIFEFWIGNPEPVYGHYREI
CCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHH
VDCLKQVRGRGVRIVYFEGNHDFHLDRFFGEKLQAEVHRAGALLEIGGQKVYVCHGDEIN
HHHHHHHHCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCC
REDYRYRAFRLLLHNPVVKALVPIFSRRIADHAAAVLSRRSSSKHSLREKRWDYRVILDS
CHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHH
FARNRFASGCDAVITGHYHLPMIKREPGRLFISLGDWITHYSYAQWLDGEFTLESYREN
HHHHHHCCCCCEEEECCEECCEEEECCCEEEEEECHHHHHHHHHHHCCCCEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA