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The map label for this gene is atoS [C]

Identifier: 197116934

GI number: 197116934

Start: 647774

End: 649369

Strand: Reverse

Name: atoS [C]

Synonym: Gbem_0536

Alternate gene names: 197116934

Gene position: 649369-647774 (Counterclockwise)

Preceding gene: 197116935

Following gene: 197116933

Centisome position: 14.07

GC content: 62.53

Gene sequence:

>1596_bases
ATGGTGACCGACGAAAACACCATCGCCATCCCGCAGCTCATTTACGAGGCGGTCAGCCGAGGGAAGCGCGAATGGGAGCA
GACCTTCGACTCCATCGCCGACCTGATCTTCATCACCGATACCAACCACACCATTTCGCGGGCCAACCGCGCCATGGCGA
AGCATTGCGGCCTGCGTCCGGAGGACCTCCCGGGACGCAAATGCTACGACCTCTTCCACGACCTGGCCTCTCCCCCCCCT
TATTGCCCGCTGAAAAGCCTGAAAGAGGGAGGTGCGCCGCGGGCGGAGGAAGTCGAGGTCGCCAAATTCTGCGGCTTCTT
CGACATCTCGGTCTCCCCTTTGTACAACGATGAAGGAACCCTCGCCGCCTGCGTCCACGTGGCCCGCGACGTCACCGAGC
GCAAGAAGGCCGAGGAGTACCGGCTGGAGTTGGAGCAGCAACTGCTGCAATCGCAAAAGCTCGAAAGCCTTGGTGTTCTC
ACCGGCGGCATCGCCCATGACTTCAACAATATCCTGATGATAATCCTCGGGCACTGCCTGCTCGCCAAGGAGAACCAGGC
CAGCGCCCCGGTCGTCGGCCACCTGGATCAGATCGAGTCCGCCGGAAACCGTGCCGCCGACCTTTGCCGCCAGATGCTGG
CCTACGCCGGCAAGGCGCCGCTGATCCAAACGCAGATCGACCTGCCGGCGCTGGTACGCGACATGGTGCAGATGCTGCAG
CCCGCGTTCAACAAGAAAGTGACCATCGAATGCGATCTCGGCGGGGACCTCCCCAAGCTGACCTGCGACGAGGCAAAGAT
CCAGCAGATCGTGATGAACTTGGTGGTGAACGCGGCCGAATCGCTGGGTGAACAGGGGGGCAAGGTCAAGGTGACCCTCT
CGCACAAGACGGTGCTGCAGGCACAGCAGGAAGTCGATTGCTTCGGCAACGTCATCCCCCCGGGAACCTATCAGTGCCTG
GAGGTTGCCGACACCGGATGCGGCATGGACCAGGAGACCCAGAAGCGGATCTTCGAACCATTTTTCACCACCAAGTTCAC
CGGGCGGGGGCTGGGGCTTTCCGCCATCAGCGGCATCATCAAGTCCCATAACGGCGCGCTGCAGCTCTGCAGCGCCCCCG
GCGCGGGGACCACTTTCAGCGTCTATTTTCCCCTCCCCCCATGCTGCCCCGCCGGCGACCAAGTCGCTGCGCCCCTCCCC
TTGCCGCTCAACGCTGCCGCCCGGCTCGAAGGGACTATCCTGCTGGTAGACGACGAGGAGGAACTTCGTGCCGTCGGCTG
TGAACTCCTCACCAGCATGGGGTTCAAGGTGATTGCCGTCAATAACGGCAGCGAGGCGCTCGCGATCTGGCAGGAGCGGA
AAAGCGAGATAGACCTCGTGCTGATGGACCTGACCATGCCGGAACTGGACGGCGTCGAGACCTACCGCGCCCTGCGCGAA
GATACCCCCACGCTCCCGGTTCTTTTTTGCAGCGGATACGGGGACCAGGACATCCGGCCCTGCATAGGCGAAGACGCCCG
CGCCGGCTTCATCGCCAAGCCTTACCAACTTGCCCAACTACAAGCGGCATTGGCTGCCCTCTGGAAAACCGCATAG

Upstream 100 bases:

>100_bases
CAAGCCTTGCCGCGCTGGACGCAGGCGTTCACCTGCACTGTTTGCCGCAGGAACTCTTTTTCTCCCCCAGGCACCCCGCA
GCAGCCACCCGGGTGCTCGC

Downstream 100 bases:

>100_bases
TGTTTCCCTCACCCTGTCCCTCAAGAGCCCCACGGCCCTGCTCTTCCCCGTGATGCAGCAGAGGGTCCCTCCGTCTGACG
CACCCTTTTACACCGGCCAA

Product: PAS domain-containing sensor histidine kinase response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MVTDENTIAIPQLIYEAVSRGKREWEQTFDSIADLIFITDTNHTISRANRAMAKHCGLRPEDLPGRKCYDLFHDLASPPP
YCPLKSLKEGGAPRAEEVEVAKFCGFFDISVSPLYNDEGTLAACVHVARDVTERKKAEEYRLELEQQLLQSQKLESLGVL
TGGIAHDFNNILMIILGHCLLAKENQASAPVVGHLDQIESAGNRAADLCRQMLAYAGKAPLIQTQIDLPALVRDMVQMLQ
PAFNKKVTIECDLGGDLPKLTCDEAKIQQIVMNLVVNAAESLGEQGGKVKVTLSHKTVLQAQQEVDCFGNVIPPGTYQCL
EVADTGCGMDQETQKRIFEPFFTTKFTGRGLGLSAISGIIKSHNGALQLCSAPGAGTTFSVYFPLPPCCPAGDQVAAPLP
LPLNAAARLEGTILLVDDEEELRAVGCELLTSMGFKVIAVNNGSEALAIWQERKSEIDLVLMDLTMPELDGVETYRALRE
DTPTLPVLFCSGYGDQDIRPCIGEDARAGFIAKPYQLAQLQAALAALWKTA

Sequences:

>Translated_531_residues
MVTDENTIAIPQLIYEAVSRGKREWEQTFDSIADLIFITDTNHTISRANRAMAKHCGLRPEDLPGRKCYDLFHDLASPPP
YCPLKSLKEGGAPRAEEVEVAKFCGFFDISVSPLYNDEGTLAACVHVARDVTERKKAEEYRLELEQQLLQSQKLESLGVL
TGGIAHDFNNILMIILGHCLLAKENQASAPVVGHLDQIESAGNRAADLCRQMLAYAGKAPLIQTQIDLPALVRDMVQMLQ
PAFNKKVTIECDLGGDLPKLTCDEAKIQQIVMNLVVNAAESLGEQGGKVKVTLSHKTVLQAQQEVDCFGNVIPPGTYQCL
EVADTGCGMDQETQKRIFEPFFTTKFTGRGLGLSAISGIIKSHNGALQLCSAPGAGTTFSVYFPLPPCCPAGDQVAAPLP
LPLNAAARLEGTILLVDDEEELRAVGCELLTSMGFKVIAVNNGSEALAIWQERKSEIDLVLMDLTMPELDGVETYRALRE
DTPTLPVLFCSGYGDQDIRPCIGEDARAGFIAKPYQLAQLQAALAALWKTA
>Mature_531_residues
MVTDENTIAIPQLIYEAVSRGKREWEQTFDSIADLIFITDTNHTISRANRAMAKHCGLRPEDLPGRKCYDLFHDLASPPP
YCPLKSLKEGGAPRAEEVEVAKFCGFFDISVSPLYNDEGTLAACVHVARDVTERKKAEEYRLELEQQLLQSQKLESLGVL
TGGIAHDFNNILMIILGHCLLAKENQASAPVVGHLDQIESAGNRAADLCRQMLAYAGKAPLIQTQIDLPALVRDMVQMLQ
PAFNKKVTIECDLGGDLPKLTCDEAKIQQIVMNLVVNAAESLGEQGGKVKVTLSHKTVLQAQQEVDCFGNVIPPGTYQCL
EVADTGCGMDQETQKRIFEPFFTTKFTGRGLGLSAISGIIKSHNGALQLCSAPGAGTTFSVYFPLPPCCPAGDQVAAPLP
LPLNAAARLEGTILLVDDEEELRAVGCELLTSMGFKVIAVNNGSEALAIWQERKSEIDLVLMDLTMPELDGVETYRALRE
DTPTLPVLFCSGYGDQDIRPCIGEDARAGFIAKPYQLAQLQAALAALWKTA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=363, Percent_Identity=26.7217630853994, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=28.8, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI48994928, Length=532, Percent_Identity=23.8721804511278, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081816, Length=428, Percent_Identity=25, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1788713, Length=280, Percent_Identity=28.2142857142857, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1790300, Length=243, Percent_Identity=25.5144032921811, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI145693157, Length=291, Percent_Identity=26.4604810996564, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789149, Length=270, Percent_Identity=20.7407407407407, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57747; Mature: 57747

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTDENTIAIPQLIYEAVSRGKREWEQTFDSIADLIFITDTNHTISRANRAMAKHCGLRP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHCCCCC
EDLPGRKCYDLFHDLASPPPYCPLKSLKEGGAPRAEEVEVAKFCGFFDISVSPLYNDEGT
CCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCH
LAACVHVARDVTERKKAEEYRLELEQQLLQSQKLESLGVLTGGIAHDFNNILMIILGHCL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
LAKENQASAPVVGHLDQIESAGNRAADLCRQMLAYAGKAPLIQTQIDLPALVRDMVQMLQ
HCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
PAFNKKVTIECDLGGDLPKLTCDEAKIQQIVMNLVVNAAESLGEQGGKVKVTLSHKTVLQ
HHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHH
AQQEVDCFGNVIPPGTYQCLEVADTGCGMDQETQKRIFEPFFTTKFTGRGLGLSAISGII
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCEECCCCCCHHHHHHHH
KSHNGALQLCSAPGAGTTFSVYFPLPPCCPAGDQVAAPLPLPLNAAARLEGTILLVDDEE
HCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCEEEEEECCHH
ELRAVGCELLTSMGFKVIAVNNGSEALAIWQERKSEIDLVLMDLTMPELDGVETYRALRE
HHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHC
DTPTLPVLFCSGYGDQDIRPCIGEDARAGFIAKPYQLAQLQAALAALWKTA
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVTDENTIAIPQLIYEAVSRGKREWEQTFDSIADLIFITDTNHTISRANRAMAKHCGLRP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHCCCCC
EDLPGRKCYDLFHDLASPPPYCPLKSLKEGGAPRAEEVEVAKFCGFFDISVSPLYNDEGT
CCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCH
LAACVHVARDVTERKKAEEYRLELEQQLLQSQKLESLGVLTGGIAHDFNNILMIILGHCL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
LAKENQASAPVVGHLDQIESAGNRAADLCRQMLAYAGKAPLIQTQIDLPALVRDMVQMLQ
HCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHH
PAFNKKVTIECDLGGDLPKLTCDEAKIQQIVMNLVVNAAESLGEQGGKVKVTLSHKTVLQ
HHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHH
AQQEVDCFGNVIPPGTYQCLEVADTGCGMDQETQKRIFEPFFTTKFTGRGLGLSAISGII
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCEECCCCCCHHHHHHHH
KSHNGALQLCSAPGAGTTFSVYFPLPPCCPAGDQVAAPLPLPLNAAARLEGTILLVDDEE
HCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCEEEEEECCHH
ELRAVGCELLTSMGFKVIAVNNGSEALAIWQERKSEIDLVLMDLTMPELDGVETYRALRE
HHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHC
DTPTLPVLFCSGYGDQDIRPCIGEDARAGFIAKPYQLAQLQAALAALWKTA
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA