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The map label for this gene is mraY

Identifier: 197116886

GI number: 197116886

Start: 589226

End: 590302

Strand: Direct

Name: mraY

Synonym: Gbem_0488

Alternate gene names: 197116886

Gene position: 589226-590302 (Clockwise)

Preceding gene: 197116885

Following gene: 197116887

Centisome position: 12.77

GC content: 60.35

Gene sequence:

>1077_bases
ATGCTTTACCATCTCCTTTACCCGCTCGCCTCTGATTACAAGCTCTTCAACGTATTCAAATACCTGACCTTCCGCTCCAT
CTACGCCATGATCACGGCCCTGCTGCTCGCCTTCATCGTGGGCCCGTGGGTGGTCAGGAAACTGGAGGCGCTACAGGCGC
GCCAGGTGATCCGGACCGACGGTCCCGAATCGCACCTGAAAAAGCAGGGAACCCCGACCATGGGCGGGGTGCTGATCCTG
GTCTGCATCGTGCTGCCGACGCTCTTATGGGCCGACCTGAAGAACGTCTTCATCTGGCTCACCCTGCTCATCATCGTGGG
GTACGGCGTCCTCGGCTTCGTGGACGACTATAAGAAGGTGGTCGAGAAGAACCCGAAGGGGCTCTCCCCGCGCCAGAAGA
TGTTCTGGCAGATGCTCTTGGCCGCAGGCGTCGGTATCTTCCTCTTCTACCTCCCCGGTTTCTCGACGGAACTCTACCTG
CCGTTCTTCAAGAGGGTGCATCCCGAGTTGGGCATCCTCTTCATCCCGTTTGTAATGCTGGTGATCGTCGGTGCCAGTAA
CGCCGTGAACCTGACCGACGGTCTCGACGGCCTCGCCATAGGTCCCGTGGCGATCAACGCCGCCACCTATCTCCTCTTCT
GCTACATAGCGGGTAACGCCAAGCTTTCCGGGTACCTGCAGATCCCCTACGTGCCGGGGGCGGGGGAGCTTGCCGTTCTT
TGCGGCGCCATGGTTGGGGCGGGGCTCGGCTTCCTCTGGTACAACTCTTATCCGGCCGAGGTCTTCATGGGCGACGTCGG
CTCCTTGTCGCTCGGCGGCGCGCTCGGGACGCTCGCGGTCCTGACCAAGCAGGAAATCCTTCTGGTGATAGTGGGCGGCG
TCTTCGTTGTGGAGGCGCTTTCGGTCATTTTCCAGGTCGGCTCCTACAAGTACCGCGGCAAGAGGATCTTCCGGATGGCG
CCGATCCACCATCACTTCGAACTGAAAGGGGTGGCGGAGCCGAAGATCATCGTGCGCTTCTGGATCATCACCATCATCCT
GGCGCTGGTGGCCATTTCCACCCTGAAGATGCGCTAG

Upstream 100 bases:

>100_bases
ACTGCATTCTTTTCAAGGGATCTAGAGGCATGAAAATGGACAAGGTGGCGCAATTGGTACGGCAGGGACTGGCATCCGCC
GCAAAAGGGGGGAATGACTG

Downstream 100 bases:

>100_bases
CGTACGCAGTAACAGTCCCCCCTCCCCTTGCGGGAGGGGGTTAGGGGGTGGGGGCAGGCACCACGACCGGCGCCCATGGC
AGCTTCACCCACCCCCCGGC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MLYHLLYPLASDYKLFNVFKYLTFRSIYAMITALLLAFIVGPWVVRKLEALQARQVIRTDGPESHLKKQGTPTMGGVLIL
VCIVLPTLLWADLKNVFIWLTLLIIVGYGVLGFVDDYKKVVEKNPKGLSPRQKMFWQMLLAAGVGIFLFYLPGFSTELYL
PFFKRVHPELGILFIPFVMLVIVGASNAVNLTDGLDGLAIGPVAINAATYLLFCYIAGNAKLSGYLQIPYVPGAGELAVL
CGAMVGAGLGFLWYNSYPAEVFMGDVGSLSLGGALGTLAVLTKQEILLVIVGGVFVVEALSVIFQVGSYKYRGKRIFRMA
PIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR

Sequences:

>Translated_358_residues
MLYHLLYPLASDYKLFNVFKYLTFRSIYAMITALLLAFIVGPWVVRKLEALQARQVIRTDGPESHLKKQGTPTMGGVLIL
VCIVLPTLLWADLKNVFIWLTLLIIVGYGVLGFVDDYKKVVEKNPKGLSPRQKMFWQMLLAAGVGIFLFYLPGFSTELYL
PFFKRVHPELGILFIPFVMLVIVGASNAVNLTDGLDGLAIGPVAINAATYLLFCYIAGNAKLSGYLQIPYVPGAGELAVL
CGAMVGAGLGFLWYNSYPAEVFMGDVGSLSLGGALGTLAVLTKQEILLVIVGGVFVVEALSVIFQVGSYKYRGKRIFRMA
PIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR
>Mature_358_residues
MLYHLLYPLASDYKLFNVFKYLTFRSIYAMITALLLAFIVGPWVVRKLEALQARQVIRTDGPESHLKKQGTPTMGGVLIL
VCIVLPTLLWADLKNVFIWLTLLIIVGYGVLGFVDDYKKVVEKNPKGLSPRQKMFWQMLLAAGVGIFLFYLPGFSTELYL
PFFKRVHPELGILFIPFVMLVIVGASNAVNLTDGLDGLAIGPVAINAATYLLFCYIAGNAKLSGYLQIPYVPGAGELAVL
CGAMVGAGLGFLWYNSYPAEVFMGDVGSLSLGGALGTLAVLTKQEILLVIVGGVFVVEALSVIFQVGSYKYRGKRIFRMA
PIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=57.8947368421053, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_GEOBB (B5EBP8)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002137313.1
- GeneID:   6783317
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_0488
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 39454; Mature: 39454

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2673f358)-; HASH(0x26b541ac)-; HASH(0x26dd5498)-; HASH(0x235f01ac)-; HASH(0x26f15568)-; HASH(0x26fbe088)-; HASH(0x267f32a8)-; HASH(0x25e31114)-; HASH(0x26a929a8)-; HASH(0x26edbe18)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYHLLYPLASDYKLFNVFKYLTFRSIYAMITALLLAFIVGPWVVRKLEALQARQVIRTD
CCEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPESHLKKQGTPTMGGVLILVCIVLPTLLWADLKNVFIWLTLLIIVGYGVLGFVDDYKKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEKNPKGLSPRQKMFWQMLLAAGVGIFLFYLPGFSTELYLPFFKRVHPELGILFIPFVML
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCCCHHHHHHHHH
VIVGASNAVNLTDGLDGLAIGPVAINAATYLLFCYIAGNAKLSGYLQIPYVPGAGELAVL
HHHCCCCCEECCCCCCCCEECHHHHHHHHHHHHHHEECCCEEEEEEEECEECCCCHHHHH
CGAMVGAGLGFLWYNSYPAEVFMGDVGSLSLGGALGTLAVLTKQEILLVIVGGVFVVEAL
HHHHHHCCHHEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIFQVGSYKYRGKRIFRMAPIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR
HHHHHHCCCEECCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MLYHLLYPLASDYKLFNVFKYLTFRSIYAMITALLLAFIVGPWVVRKLEALQARQVIRTD
CCEEEECHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPESHLKKQGTPTMGGVLILVCIVLPTLLWADLKNVFIWLTLLIIVGYGVLGFVDDYKKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEKNPKGLSPRQKMFWQMLLAAGVGIFLFYLPGFSTELYLPFFKRVHPELGILFIPFVML
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCCCHHHHHHHHH
VIVGASNAVNLTDGLDGLAIGPVAINAATYLLFCYIAGNAKLSGYLQIPYVPGAGELAVL
HHHCCCCCEECCCCCCCCEECHHHHHHHHHHHHHHEECCCEEEEEEEECEECCCCHHHHH
CGAMVGAGLGFLWYNSYPAEVFMGDVGSLSLGGALGTLAVLTKQEILLVIVGGVFVVEAL
HHHHHHCCHHEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVIFQVGSYKYRGKRIFRMAPIHHHFELKGVAEPKIIVRFWIITIILALVAISTLKMR
HHHHHHCCCEECCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA