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The map label for this gene is nreB [H]

Identifier: 197116848

GI number: 197116848

Start: 541868

End: 544210

Strand: Direct

Name: nreB [H]

Synonym: Gbem_0450

Alternate gene names: 197116848

Gene position: 541868-544210 (Clockwise)

Preceding gene: 197116847

Following gene: 197116849

Centisome position: 11.74

GC content: 63.51

Gene sequence:

>2343_bases
GTGACCTTTGCCGAGCGGATGAAAATCAGCTCCATCATGTTCTTCAGCCTGCTCGTTTTCGGAGCGGCCGTCTTGTTCTG
GTCCTCGCGGGAGTTGAACTCGGCCCGACAAAACGACGTGCTGTCGGATGACATCCAGACCATCGTTTTCGAGCGTGCCA
CGCTGCGCGACGAGTTTTTCCTCTACGGTCTGGAACGCGCCAGGGTGCAGTGGTTCGGCCTGAACCGCGACGCGGAGGCG
TCGATCCGGCTGGGGAACGAGCATCTGCGCGCCCCGCAAGAGCGCGAGGTCCTGGAGAAGGTGCAGGCGGACCTCAGGGA
ATCGGAGCTGGTTTCGCAGCGGCTGGTCGAGCTTTTGCGCGGAAAGTCGGGCCCGGAGCTGGAGAGAGCGCACCACGACG
AGTTGGCCAGCCGGCTCTACAGCCAGATCATGCTTAAGGATTCCGCCCTGCAGCAATCCTCGGCAGCCCTGCAGGAGTTG
ACCCGCCAGCGCTACAACAGGGCAAACTTTCGCACCATATTCCTCACCTTCGCCTTCGTGCTGTTGGTGGTCGCTGGGGG
AAGGGCCAATGCCTTTTTCATCAATTCCCTTTTGCGCCGCAGGCTGCAGCTCTTAAACGAAGGTGTGGCGAGGATCGCAG
CGGGGGATTTCAGCCACAGGATGCAGTGCCGGGGAAGCGACGAACTTGCGCTTTTTGCCGGGGTATTCAACTGCGTTCTC
GACAAGGTCCAGGACTACACCGGGCAGCTGGAAAAAAGCCACGACCTGTTGAGCGGCCTCTCCAGCCAGGTCCCCGGCAT
ACTGTTCCAGGCCTGCCTCACCCCGGATGGCCTCTTCAGTACCCCCTACGTGAGCAGGGGGGGGGACGAGCTCAATCAGG
GCGACGCAGCGGCGCCTCTCCAGGAGCCTGCCCAGCTCTTCGAGAGGTTACACCCCGAGAAGTACCAGGCCATACTGGGG
ACCTTTCGGCGATCGGCCGAGACGCTTGAGCCTTGGGAGCACGAGTTCCGCATCGATGTCCCGGACAGGGGAATGCGGTG
GCTGCGCGGGCAGGCGCGCCCCATGCGGCTTCCCGACGGCGGCACCCTCTGGCACGGGTTCATCTCGGACATAACCGAGA
GGAAACGGGCTGAGGAGGCGCTGCACCGAAGCGAGAGCCGCTACCGGATGCAGCTGCAGGAATTGACCAACATCTACACC
CACACTGCCGTCGGCCTCTTCGCCGTGGACCGCGAGATGCGCTATCTGCGCCTCAACGAGCAGATGGCCGGCTACAACTG
CAGGCCCATGGACGAGCATGTCGGCAGAACCATCGACGAGGTGCACCCCCCGGCGTTCGTGGTCGCCCTCAAGGAGATGT
GGCGCCCGGTCCTGGAACGGGGCGAATCCCTGCTGAACCTGGAGGTCCAGGGGCAAGCGGATTGGCCCAGCGGGGAGCGC
CATTGGCTGGTGAGCTTCCAGCCCCTGTTCGCTGAGACCGGCGCGGTCATCGGCCTCACCGGATCGGTGATGGATATAAC
CGAGCGCAAGGTCGCCGAGCAGGTACTTTTGGGGGCGAGGCAGCAACTGGAGCGGGAGGTGCAGCTTAGGACGGCGAAAC
TTTCCCTGACCAACAAGCATCTGATCCAGGAGATCGAGGTGCGCAAGAAGGTTGAGGTCGAACTCCTGGCCCAGCAGCAG
AAGCTGCAAGAGATGGCATTCGAGATCTCGATGGCGGAGGAGCGGGAGCGCGACCGCATCGCGAGCGAACTGCACGACCA
GGTGGGGCAGCGCCTGATCCTCGCCAAGATCAAGCTGGACTCCCTGGCGAGCAACCTTCCCCTGGGGGAGTGCGAGGCGG
AGGCAATGGGGGTCGAGACCCTGATCGAGCAGACCCTTCAGGACATCCGGTCGCTCACCTTTCAGATCCGTCCCCCCGTT
TTGGCCACCGCCGGCCTGGAAGCCGCGCTGCGCTGGCTGGGGGAGGAACTGCACGCCGACTTCGGTCTGGAAGTGGAGTT
CAGCGACGACGGCAAGGACAAACCGCTCCGCTACGAGGTGCGCTCCACCGTGTTCCAGGCGGTCCGCGAGTTGCTGCTCA
ACGTGGCCAAGCACGCTGGGACCAAGAAATGCCGGGTGCGCTTCACCCGGGTCGGGGACCGCATCGTGATCGAGGTGGAG
GATGACGGGACAGGCCTCAAGCCAGGCGCCGGCGACGGCACCCGTTCCAGAAGCGGCGGGTTCGGGCTGTTGAATGTTCA
GCAGAAGGTAGAGCATCTCGGCGGGGTGTTCAGCATAGAGTCCAGGCCGCAGGGAGGCACCAGGGCTGCCATCGAGGTTC
CCGTGGAAACCGAGACAAAATAG

Upstream 100 bases:

>100_bases
CCGGAGGCGGCCATGCCGAATTATCTTGAGTACATTGACGTCAGGCCACTGCAGGAGGTGAAGCCTGAAGCGATAAAGAT
CAACACCAGAAGGTGAGCGC

Downstream 100 bases:

>100_bases
GAGGCGGGATATGAGTATGAAGGTACTGATCGTGGACGACCACACCATAGTGAGGCAGGGGTTGCGCGTACTGATCGACA
AGGAACAGGATATGGAGGTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 780; Mature: 779

Protein sequence:

>780_residues
MTFAERMKISSIMFFSLLVFGAAVLFWSSRELNSARQNDVLSDDIQTIVFERATLRDEFFLYGLERARVQWFGLNRDAEA
SIRLGNEHLRAPQEREVLEKVQADLRESELVSQRLVELLRGKSGPELERAHHDELASRLYSQIMLKDSALQQSSAALQEL
TRQRYNRANFRTIFLTFAFVLLVVAGGRANAFFINSLLRRRLQLLNEGVARIAAGDFSHRMQCRGSDELALFAGVFNCVL
DKVQDYTGQLEKSHDLLSGLSSQVPGILFQACLTPDGLFSTPYVSRGGDELNQGDAAAPLQEPAQLFERLHPEKYQAILG
TFRRSAETLEPWEHEFRIDVPDRGMRWLRGQARPMRLPDGGTLWHGFISDITERKRAEEALHRSESRYRMQLQELTNIYT
HTAVGLFAVDREMRYLRLNEQMAGYNCRPMDEHVGRTIDEVHPPAFVVALKEMWRPVLERGESLLNLEVQGQADWPSGER
HWLVSFQPLFAETGAVIGLTGSVMDITERKVAEQVLLGARQQLEREVQLRTAKLSLTNKHLIQEIEVRKKVEVELLAQQQ
KLQEMAFEISMAEERERDRIASELHDQVGQRLILAKIKLDSLASNLPLGECEAEAMGVETLIEQTLQDIRSLTFQIRPPV
LATAGLEAALRWLGEELHADFGLEVEFSDDGKDKPLRYEVRSTVFQAVRELLLNVAKHAGTKKCRVRFTRVGDRIVIEVE
DDGTGLKPGAGDGTRSRSGGFGLLNVQQKVEHLGGVFSIESRPQGGTRAAIEVPVETETK

Sequences:

>Translated_780_residues
MTFAERMKISSIMFFSLLVFGAAVLFWSSRELNSARQNDVLSDDIQTIVFERATLRDEFFLYGLERARVQWFGLNRDAEA
SIRLGNEHLRAPQEREVLEKVQADLRESELVSQRLVELLRGKSGPELERAHHDELASRLYSQIMLKDSALQQSSAALQEL
TRQRYNRANFRTIFLTFAFVLLVVAGGRANAFFINSLLRRRLQLLNEGVARIAAGDFSHRMQCRGSDELALFAGVFNCVL
DKVQDYTGQLEKSHDLLSGLSSQVPGILFQACLTPDGLFSTPYVSRGGDELNQGDAAAPLQEPAQLFERLHPEKYQAILG
TFRRSAETLEPWEHEFRIDVPDRGMRWLRGQARPMRLPDGGTLWHGFISDITERKRAEEALHRSESRYRMQLQELTNIYT
HTAVGLFAVDREMRYLRLNEQMAGYNCRPMDEHVGRTIDEVHPPAFVVALKEMWRPVLERGESLLNLEVQGQADWPSGER
HWLVSFQPLFAETGAVIGLTGSVMDITERKVAEQVLLGARQQLEREVQLRTAKLSLTNKHLIQEIEVRKKVEVELLAQQQ
KLQEMAFEISMAEERERDRIASELHDQVGQRLILAKIKLDSLASNLPLGECEAEAMGVETLIEQTLQDIRSLTFQIRPPV
LATAGLEAALRWLGEELHADFGLEVEFSDDGKDKPLRYEVRSTVFQAVRELLLNVAKHAGTKKCRVRFTRVGDRIVIEVE
DDGTGLKPGAGDGTRSRSGGFGLLNVQQKVEHLGGVFSIESRPQGGTRAAIEVPVETETK
>Mature_779_residues
TFAERMKISSIMFFSLLVFGAAVLFWSSRELNSARQNDVLSDDIQTIVFERATLRDEFFLYGLERARVQWFGLNRDAEAS
IRLGNEHLRAPQEREVLEKVQADLRESELVSQRLVELLRGKSGPELERAHHDELASRLYSQIMLKDSALQQSSAALQELT
RQRYNRANFRTIFLTFAFVLLVVAGGRANAFFINSLLRRRLQLLNEGVARIAAGDFSHRMQCRGSDELALFAGVFNCVLD
KVQDYTGQLEKSHDLLSGLSSQVPGILFQACLTPDGLFSTPYVSRGGDELNQGDAAAPLQEPAQLFERLHPEKYQAILGT
FRRSAETLEPWEHEFRIDVPDRGMRWLRGQARPMRLPDGGTLWHGFISDITERKRAEEALHRSESRYRMQLQELTNIYTH
TAVGLFAVDREMRYLRLNEQMAGYNCRPMDEHVGRTIDEVHPPAFVVALKEMWRPVLERGESLLNLEVQGQADWPSGERH
WLVSFQPLFAETGAVIGLTGSVMDITERKVAEQVLLGARQQLEREVQLRTAKLSLTNKHLIQEIEVRKKVEVELLAQQQK
LQEMAFEISMAEERERDRIASELHDQVGQRLILAKIKLDSLASNLPLGECEAEAMGVETLIEQTLQDIRSLTFQIRPPVL
ATAGLEAALRWLGEELHADFGLEVEFSDDGKDKPLRYEVRSTVFQAVRELLLNVAKHAGTKKCRVRFTRVGDRIVIEVED
DGTGLKPGAGDGTRSRSGGFGLLNVQQKVEHLGGVFSIESRPQGGTRAAIEVPVETETK

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=246, Percent_Identity=27.6422764227642, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88278; Mature: 88147

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50885 HAMP ; PS50113 PAC ; PS50109 HIS_KIN ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFAERMKISSIMFFSLLVFGAAVLFWSSRELNSARQNDVLSDDIQTIVFERATLRDEFF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LYGLERARVQWFGLNRDAEASIRLGNEHLRAPQEREVLEKVQADLRESELVSQRLVELLR
HHHHHHHEEEEEECCCCCCCCEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKSGPELERAHHDELASRLYSQIMLKDSALQQSSAALQELTRQRYNRANFRTIFLTFAFV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LLVVAGGRANAFFINSLLRRRLQLLNEGVARIAAGDFSHRMQCRGSDELALFAGVFNCVL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHH
DKVQDYTGQLEKSHDLLSGLSSQVPGILFQACLTPDGLFSTPYVSRGGDELNQGDAAAPL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCH
QEPAQLFERLHPEKYQAILGTFRRSAETLEPWEHEFRIDVPDRGMRWLRGQARPMRLPDG
HHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHCCCCCCCCCCCC
GTLWHGFISDITERKRAEEALHRSESRYRMQLQELTNIYTHTAVGLFAVDREMRYLRLNE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMAGYNCRPMDEHVGRTIDEVHPPAFVVALKEMWRPVLERGESLLNLEVQGQADWPSGER
HHCCCCCCCCHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCC
HWLVSFQPLFAETGAVIGLTGSVMDITERKVAEQVLLGARQQLEREVQLRTAKLSLTNKH
EEEEEECHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIQEIEVRKKVEVELLAQQQKLQEMAFEISMAEERERDRIASELHDQVGQRLILAKIKLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLASNLPLGECEAEAMGVETLIEQTLQDIRSLTFQIRPPVLATAGLEAALRWLGEELHAD
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHCCC
FGLEVEFSDDGKDKPLRYEVRSTVFQAVRELLLNVAKHAGTKKCRVRFTRVGDRIVIEVE
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCEEEEEEC
DDGTGLKPGAGDGTRSRSGGFGLLNVQQKVEHLGGVFSIESRPQGGTRAAIEVPVETETK
CCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCEEEECCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
TFAERMKISSIMFFSLLVFGAAVLFWSSRELNSARQNDVLSDDIQTIVFERATLRDEFF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LYGLERARVQWFGLNRDAEASIRLGNEHLRAPQEREVLEKVQADLRESELVSQRLVELLR
HHHHHHHEEEEEECCCCCCCCEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GKSGPELERAHHDELASRLYSQIMLKDSALQQSSAALQELTRQRYNRANFRTIFLTFAFV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LLVVAGGRANAFFINSLLRRRLQLLNEGVARIAAGDFSHRMQCRGSDELALFAGVFNCVL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHH
DKVQDYTGQLEKSHDLLSGLSSQVPGILFQACLTPDGLFSTPYVSRGGDELNQGDAAAPL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCH
QEPAQLFERLHPEKYQAILGTFRRSAETLEPWEHEFRIDVPDRGMRWLRGQARPMRLPDG
HHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHCCCCCCCCCCCC
GTLWHGFISDITERKRAEEALHRSESRYRMQLQELTNIYTHTAVGLFAVDREMRYLRLNE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMAGYNCRPMDEHVGRTIDEVHPPAFVVALKEMWRPVLERGESLLNLEVQGQADWPSGER
HHCCCCCCCCHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCC
HWLVSFQPLFAETGAVIGLTGSVMDITERKVAEQVLLGARQQLEREVQLRTAKLSLTNKH
EEEEEECHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIQEIEVRKKVEVELLAQQQKLQEMAFEISMAEERERDRIASELHDQVGQRLILAKIKLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLASNLPLGECEAEAMGVETLIEQTLQDIRSLTFQIRPPVLATAGLEAALRWLGEELHAD
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHCCC
FGLEVEFSDDGKDKPLRYEVRSTVFQAVRELLLNVAKHAGTKKCRVRFTRVGDRIVIEVE
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEECCCEEEEEEC
DDGTGLKPGAGDGTRSRSGGFGLLNVQQKVEHLGGVFSIESRPQGGTRAAIEVPVETETK
CCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCEEEECCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA