Click here to switch to the map view.

The map label for this gene is ispA [H]

Identifier: 197104377

GI number: 197104377

Start: 1003632

End: 1004510

Strand: Direct

Name: ispA [H]

Synonym: PHZ_c0911

Alternate gene names: 197104377

Gene position: 1003632-1004510 (Clockwise)

Preceding gene: 197104376

Following gene: 197104378

Centisome position: 25.11

GC content: 72.58

Gene sequence:

>879_bases
ATGGATCTGTCGCGGCGCGTGGCCGAGGCCGCCGACCTGGTGACGGTGGCCCTCGACGAGCTCCTGCCCCGGGGGGAGGG
GCCGGAAAGCCGCCTGACGGAGGCCATGCGCTACGCGGCCCTGGGGCCCGGCAAGCGCCTGCGCACCTTCTTCGCCCTGG
AGACCGGGCGGATGTTCGACCTGGACGACCGGCCGGTGCTGCGCTCGGCCTGCGCGCTGGAATGCATCCACGCCTACAGC
CTGGTCCACGACGACCTGCCGTGCATGGACGACGACGATGTCCGCCGCGGCCGGCCCACGGTGCACAAGGCCTACGACGA
GGCGACCGCGGTGCTGGCGGGCGACGCGCTGCAGACCGCCGCCTTCGAGATCCTGGCCCATCCCGACACCCATCCCGACG
GCGGGATCCGCGCCGAGCTGGTGGCGCGGCTGGCCCACGCGTCCGGCGCCCGCGGCATGGCGGGCGGTCAGATGATCGAC
ATCCTGGGCGTGCGCGAGGACCTGGGCGGCGTCGCGCGGATGCAGCGGCTGAAGACCGGCGCGCTGATCGCCTGCGCCTT
CGAGCTGCCGCTGGTGCTGGCCCGGGCGATGGACGGCGAGCGGCACGCCCTGATGAACTTCGCCCATGACCTGGGCCTCG
CCTATCAGATCGTCGACGACCTGCTCGATGCCGAGGGCGACGAGGCGGCCATGGGCAAGGCGGCGCGCAAGGACGTCGAG
AAGGGCAAGGCCAATTTCGTCACCCTGCTGGGCGTGGACGCCGCCCGCGAGCGCCTGGGGGTGCTCGCCGGCCAGACCAA
GGCGCACCTGGATCCATTCGGCCGCCGGGCCGATTTCCTGCGGGCCAGCGTCGATTTCGTGTTAGAGCGCCGGCAGTAG

Upstream 100 bases:

>100_bases
CCCACTGCGAGACGCGGCTCGAGGCCGCCCGGCTGCGGGTCGAGAAGATCGTCATGGGGGCCGGCGGCGCGCCCGCCAGC
GAACCCGCCGAGTTCGGCTG

Downstream 100 bases:

>100_bases
CCGCAACCGCCCCCAAAGCGTTTCCTATGCCCCCTGTCACGCCCCTGCTCGACACGGTTTCCTCGCCCGCGGACACGCGC
GGCCTCTCGATCGCCCAGCT

Product: geranyltranstransferase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDLSRRVAEAADLVTVALDELLPRGEGPESRLTEAMRYAALGPGKRLRTFFALETGRMFDLDDRPVLRSACALECIHAYS
LVHDDLPCMDDDDVRRGRPTVHKAYDEATAVLAGDALQTAAFEILAHPDTHPDGGIRAELVARLAHASGARGMAGGQMID
ILGVREDLGGVARMQRLKTGALIACAFELPLVLARAMDGERHALMNFAHDLGLAYQIVDDLLDAEGDEAAMGKAARKDVE
KGKANFVTLLGVDAARERLGVLAGQTKAHLDPFGRRADFLRASVDFVLERRQ

Sequences:

>Translated_292_residues
MDLSRRVAEAADLVTVALDELLPRGEGPESRLTEAMRYAALGPGKRLRTFFALETGRMFDLDDRPVLRSACALECIHAYS
LVHDDLPCMDDDDVRRGRPTVHKAYDEATAVLAGDALQTAAFEILAHPDTHPDGGIRAELVARLAHASGARGMAGGQMID
ILGVREDLGGVARMQRLKTGALIACAFELPLVLARAMDGERHALMNFAHDLGLAYQIVDDLLDAEGDEAAMGKAARKDVE
KGKANFVTLLGVDAARERLGVLAGQTKAHLDPFGRRADFLRASVDFVLERRQ
>Mature_292_residues
MDLSRRVAEAADLVTVALDELLPRGEGPESRLTEAMRYAALGPGKRLRTFFALETGRMFDLDDRPVLRSACALECIHAYS
LVHDDLPCMDDDDVRRGRPTVHKAYDEATAVLAGDALQTAAFEILAHPDTHPDGGIRAELVARLAHASGARGMAGGQMID
ILGVREDLGGVARMQRLKTGALIACAFELPLVLARAMDGERHALMNFAHDLGLAYQIVDDLLDAEGDEAAMGKAARKDVE
KGKANFVTLLGVDAARERLGVLAGQTKAHLDPFGRRADFLRASVDFVLERRQ

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786623, Length=302, Percent_Identity=39.4039735099338, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1789578, Length=209, Percent_Identity=29.1866028708134, Blast_Score=85, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24651612, Length=188, Percent_Identity=28.1914893617021, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 31650; Mature: 31650

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSRRVAEAADLVTVALDELLPRGEGPESRLTEAMRYAALGPGKRLRTFFALETGRMFD
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHEEECCCEEC
LDDRPVLRSACALECIHAYSLVHDDLPCMDDDDVRRGRPTVHKAYDEATAVLAGDALQTA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCHHHHHH
AFEILAHPDTHPDGGIRAELVARLAHASGARGMAGGQMIDILGVREDLGGVARMQRLKTG
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCC
ALIACAFELPLVLARAMDGERHALMNFAHDLGLAYQIVDDLLDAEGDEAAMGKAARKDVE
HHEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KGKANFVTLLGVDAARERLGVLAGQTKAHLDPFGRRADFLRASVDFVLERRQ
CCCCCEEEEEECHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLSRRVAEAADLVTVALDELLPRGEGPESRLTEAMRYAALGPGKRLRTFFALETGRMFD
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHEEECCCEEC
LDDRPVLRSACALECIHAYSLVHDDLPCMDDDDVRRGRPTVHKAYDEATAVLAGDALQTA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCHHHHHH
AFEILAHPDTHPDGGIRAELVARLAHASGARGMAGGQMIDILGVREDLGGVARMQRLKTG
HHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCC
ALIACAFELPLVLARAMDGERHALMNFAHDLGLAYQIVDDLLDAEGDEAAMGKAARKDVE
HHEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
KGKANFVTLLGVDAARERLGVLAGQTKAHLDPFGRRADFLRASVDFVLERRQ
CCCCCEEEEEECHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9515931 [H]