Click here to switch to the map view.

The map label for this gene is yhcW [H]

Identifier: 197104342

GI number: 197104342

Start: 969332

End: 970000

Strand: Direct

Name: yhcW [H]

Synonym: PHZ_c0876

Alternate gene names: 197104342

Gene position: 969332-970000 (Clockwise)

Preceding gene: 197104341

Following gene: 197104345

Centisome position: 24.26

GC content: 71.45

Gene sequence:

>669_bases
ATGGCCCTCCCGCGTCCCGTCAAAGCCGTCGTCTTCGACATGGACGGCCTGCTGGTGGACACCGAGACGGTCTACTGCGA
GGCCCTGGTCGCCGAGTGCGCCCATATGGGCCACGAGCTGCCCGACGACGTCCTGAAGCGGATGATCGGGCACATCTGGC
TGAACAGCGCGCTCGTGCTCACCGACCACTTCGGCCCGGGCTTCGACACCGATGCGCTGCGCGACGGCTCGACCCGGCGC
TTCCGCGAGATCGTCCACGCCGGGGTGGCGCTCAAGGCCGGGGTGCTGGAGATGCTGGACCACCTGGACGCCCTCGGCCT
GCCGCGGGCGATCGCCACCTCGTCGCGGCGCGAGGCGGTGGAGCACCACATCGGCGGCCACGGCCTGCTGGAGCGGTTCC
ACGCGGTGCTGGCCAACGGCGACTATCCGCGGCCCAAGCCGAACCCCGATCCCTATCTGCTGGCCGCCGAGCGGCTGGGC
GTCGATCCGGCCGACTGCCTGGCCCTGGAGGACAGCCACAACGGCGTGCGCGCCGCCTCCGCCGCCGGCATGATGACGGT
CATGGTCCCCGACATGCTGGACCCGACCGACGAGATGCACGCCCTGTGCGTCCGCATCGCCCGCGACCTGCACGAGGTCC
GCGGCTTCCTGGCGCTCCAGGCGAGCTGA

Upstream 100 bases:

>100_bases
CGCGCTGCTCTACTTCCAGGGCTACCGGGCCGACGAGTTCGTCACGGATTGAAACGGCAGGTGACTTGCCGCCCGGCCGA
ACCGGCTTAAATCCACGGGC

Downstream 100 bases:

>100_bases
GGAAACGAAAAACCCCTCCCCGGACGGGCCGGAGAGGGGAAGGGGATTGCGGTAAGCAGTCAGATTACTTTCGTAATCCA
ACGTCAGGTTACGCGCGTAA

Product: hydrolase, haloacid dehalogenase-like family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MALPRPVKAVVFDMDGLLVDTETVYCEALVAECAHMGHELPDDVLKRMIGHIWLNSALVLTDHFGPGFDTDALRDGSTRR
FREIVHAGVALKAGVLEMLDHLDALGLPRAIATSSRREAVEHHIGGHGLLERFHAVLANGDYPRPKPNPDPYLLAAERLG
VDPADCLALEDSHNGVRAASAAGMMTVMVPDMLDPTDEMHALCVRIARDLHEVRGFLALQAS

Sequences:

>Translated_222_residues
MALPRPVKAVVFDMDGLLVDTETVYCEALVAECAHMGHELPDDVLKRMIGHIWLNSALVLTDHFGPGFDTDALRDGSTRR
FREIVHAGVALKAGVLEMLDHLDALGLPRAIATSSRREAVEHHIGGHGLLERFHAVLANGDYPRPKPNPDPYLLAAERLG
VDPADCLALEDSHNGVRAASAAGMMTVMVPDMLDPTDEMHALCVRIARDLHEVRGFLALQAS
>Mature_221_residues
ALPRPVKAVVFDMDGLLVDTETVYCEALVAECAHMGHELPDDVLKRMIGHIWLNSALVLTDHFGPGFDTDALRDGSTRRF
REIVHAGVALKAGVLEMLDHLDALGLPRAIATSSRREAVEHHIGGHGLLERFHAVLANGDYPRPKPNPDPYLLAAERLGV
DPADCLALEDSHNGVRAASAAGMMTVMVPDMLDPTDEMHALCVRIARDLHEVRGFLALQAS

Specific function: Unknown

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=195, Percent_Identity=35.3846153846154, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI207113149, Length=218, Percent_Identity=31.651376146789, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI296011030, Length=195, Percent_Identity=30.7692307692308, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI296011028, Length=166, Percent_Identity=30.7228915662651, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1788021, Length=198, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1789046, Length=182, Percent_Identity=30.2197802197802, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789787, Length=206, Percent_Identity=30.5825242718447, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17554716, Length=211, Percent_Identity=30.8056872037915, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI116008157, Length=197, Percent_Identity=40.1015228426396, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17137324, Length=193, Percent_Identity=37.3056994818653, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI45550911, Length=195, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24580849, Length=163, Percent_Identity=30.6748466257669, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24146; Mature: 24015

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPRPVKAVVFDMDGLLVDTETVYCEALVAECAHMGHELPDDVLKRMIGHIWLNSALVL
CCCCCCHHHEEECCCCEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEE
TDHFGPGFDTDALRDGSTRRFREIVHAGVALKAGVLEMLDHLDALGLPRAIATSSRREAV
EECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
EHHIGGHGLLERFHAVLANGDYPRPKPNPDPYLLAAERLGVDPADCLALEDSHNGVRAAS
HHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHCCCHHHHEEECCCCCCCHHHH
AAGMMTVMVPDMLDPTDEMHALCVRIARDLHEVRGFLALQAS
HHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALPRPVKAVVFDMDGLLVDTETVYCEALVAECAHMGHELPDDVLKRMIGHIWLNSALVL
CCCCCHHHEEECCCCEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEEE
TDHFGPGFDTDALRDGSTRRFREIVHAGVALKAGVLEMLDHLDALGLPRAIATSSRREAV
EECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
EHHIGGHGLLERFHAVLANGDYPRPKPNPDPYLLAAERLGVDPADCLALEDSHNGVRAAS
HHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHCCCHHHHEEECCCCCCCHHHH
AAGMMTVMVPDMLDPTDEMHALCVRIARDLHEVRGFLALQAS
HHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]