Click here to switch to the map view.

The map label for this gene is accA

Identifier: 197104214

GI number: 197104214

Start: 820038

End: 821000

Strand: Direct

Name: accA

Synonym: PHZ_c0748

Alternate gene names: 197104214

Gene position: 820038-821000 (Clockwise)

Preceding gene: 197104212

Following gene: 197104215

Centisome position: 20.52

GC content: 70.82

Gene sequence:

>963_bases
ATGGCCGCCCACTATCTCGAGTTCGAGCGCCCCATCGCGGACCTCGAAGCCAAGATCGAGGAACTCTCGCGCCTTTCCGA
GACCGCCAGCCCGGGCGCCTTCGACGGCGAGATCGAGTCGCTGCGGGCCCGCGCGCAGGACATGCGCCGCGAGGCCTACG
CCAATCTCGACGCCTGGCAGAAGACCCAGGTGGCCCGCCATCCCGACCGGCCGCACTTCGTCGACTACGTCGCCGCGCTG
ATCGAGGACTTCCAGGAGCTCCGCGGCGACCGTAAGTTCGCCGACGACCAGGCGATCATGGGCGGCCTCGGCCGCTTCCG
CGGCATGCCGGTGGTGGTCATGGGCCACGAGAAGGGCCGCGACACCGTCACCCGGGTGAAGCACAACTTCGGCTACGCCC
GCCCCGAGGGCTACCGCAAGGCGATCCGCCTGATGGAGCTGGCCGAGCGGTTCAACCTGCCGGTCGTCAGCTTCGTGGAC
ACCGCCGGCGCCTATCCGGGCGTCGCCTCCGAGGAGCGGGGCGTCGCCGAGGCTATCGCCCGCTCCACCGAGAAGTGCCT
GATGCTGGAGACGCCCAACGTGGCGGTCATCACCGGCGAGGGCGGCTCGGGCGGCGCCATCGCCATCGCCGCGACCAGCC
GGGTGCTGATCCTGGAGCACGCCATCTACTCGGTCATCGCGCCCGAGGGGGCCAACTCGATCCTATGGCGCGGCGCGCGA
ACCGCTGGCGAGGCGGCCAAGGCGATGAAGATCACCGCCCAGGACTTGGAGCGGATGAAGATCGTCGACCGGATCATCCG
CGAGCCGGCGGGCGGCGCCCATTCCGACCCCGAGGCCGCCATGCAGGCCGTCGGCGACGCGGTCGAGGAGGAGCTGAAGG
CGCTCCTGGCCCTCGATGCGGCGACCCTCAAGGCGCAGCGCGCCGAGCGCTTCTACGCCATCGGCCGCTCGGGGCTGCAG
TAG

Upstream 100 bases:

>100_bases
GCTTGTTAGGGCGACGGTTCACGCCTAATTTCCGGCGCTCTCTCGACGACCCCTCTCCAGACGACCCCACGACCGACGAC
TCAGGGAAGCGATCCTCCGC

Downstream 100 bases:

>100_bases
CTCAAGCCCTTGCCTGACGTGGCGTCTGCCGCTTCAGTGTCCTCCAAACATCTGTTTGGAGGCGACGACCCATGGCGCTC
AAGACCCGTTTCACCGAGAC

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MAAHYLEFERPIADLEAKIEELSRLSETASPGAFDGEIESLRARAQDMRREAYANLDAWQKTQVARHPDRPHFVDYVAAL
IEDFQELRGDRKFADDQAIMGGLGRFRGMPVVVMGHEKGRDTVTRVKHNFGYARPEGYRKAIRLMELAERFNLPVVSFVD
TAGAYPGVASEERGVAEAIARSTEKCLMLETPNVAVITGEGGSGGAIAIAATSRVLILEHAIYSVIAPEGANSILWRGAR
TAGEAAKAMKITAQDLERMKIVDRIIREPAGGAHSDPEAAMQAVGDAVEEELKALLALDAATLKAQRAERFYAIGRSGLQ

Sequences:

>Translated_320_residues
MAAHYLEFERPIADLEAKIEELSRLSETASPGAFDGEIESLRARAQDMRREAYANLDAWQKTQVARHPDRPHFVDYVAAL
IEDFQELRGDRKFADDQAIMGGLGRFRGMPVVVMGHEKGRDTVTRVKHNFGYARPEGYRKAIRLMELAERFNLPVVSFVD
TAGAYPGVASEERGVAEAIARSTEKCLMLETPNVAVITGEGGSGGAIAIAATSRVLILEHAIYSVIAPEGANSILWRGAR
TAGEAAKAMKITAQDLERMKIVDRIIREPAGGAHSDPEAAMQAVGDAVEEELKALLALDAATLKAQRAERFYAIGRSGLQ
>Mature_319_residues
AAHYLEFERPIADLEAKIEELSRLSETASPGAFDGEIESLRARAQDMRREAYANLDAWQKTQVARHPDRPHFVDYVAALI
EDFQELRGDRKFADDQAIMGGLGRFRGMPVVVMGHEKGRDTVTRVKHNFGYARPEGYRKAIRLMELAERFNLPVVSFVDT
AGAYPGVASEERGVAEAIARSTEKCLMLETPNVAVITGEGGSGGAIAIAATSRVLILEHAIYSVIAPEGANSILWRGART
AGEAAKAMKITAQDLERMKIVDRIIREPAGGAHSDPEAAMQAVGDAVEEELKALLALDAATLKAQRAERFYAIGRSGLQ

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=317, Percent_Identity=47.0031545741325, Blast_Score=305, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_PHEZH (B4RG38)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002129591.1
- GeneID:   6790241
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c0748
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 34889; Mature: 34758

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAHYLEFERPIADLEAKIEELSRLSETASPGAFDGEIESLRARAQDMRREAYANLDAWQ
CCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
KTQVARHPDRPHFVDYVAALIEDFQELRGDRKFADDQAIMGGLGRFRGMPVVVMGHEKGR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCC
DTVTRVKHNFGYARPEGYRKAIRLMELAERFNLPVVSFVDTAGAYPGVASEERGVAEAIA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHH
RSTEKCLMLETPNVAVITGEGGSGGAIAIAATSRVLILEHAIYSVIAPEGANSILWRGAR
HCHHCEEEEECCCEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHCCCCC
TAGEAAKAMKITAQDLERMKIVDRIIREPAGGAHSDPEAAMQAVGDAVEEELKALLALDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ATLKAQRAERFYAIGRSGLQ
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AAHYLEFERPIADLEAKIEELSRLSETASPGAFDGEIESLRARAQDMRREAYANLDAWQ
CCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
KTQVARHPDRPHFVDYVAALIEDFQELRGDRKFADDQAIMGGLGRFRGMPVVVMGHEKGR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCC
DTVTRVKHNFGYARPEGYRKAIRLMELAERFNLPVVSFVDTAGAYPGVASEERGVAEAIA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHH
RSTEKCLMLETPNVAVITGEGGSGGAIAIAATSRVLILEHAIYSVIAPEGANSILWRGAR
HCHHCEEEEECCCEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHCCCCC
TAGEAAKAMKITAQDLERMKIVDRIIREPAGGAHSDPEAAMQAVGDAVEEELKALLALDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ATLKAQRAERFYAIGRSGLQ
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA