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The map label for this gene is blh [H]

Identifier: 197104200

GI number: 197104200

Start: 806631

End: 807491

Strand: Direct

Name: blh [H]

Synonym: PHZ_c0734

Alternate gene names: 197104200

Gene position: 806631-807491 (Clockwise)

Preceding gene: 197104198

Following gene: 197104201

Centisome position: 20.18

GC content: 71.78

Gene sequence:

>861_bases
ATGCGACCCCACGTCCAGACGTTCTTCGACCGCGCCACCTCGACCGCCACGCACCTCGTCTCGGACCCGGCGACCGGCGT
CGCCGCCGTCGTCGATCCGGTGCTGGATTTCGACCCCAAGTCGGCGAAGCTCTCGACCCGCTCGGCCGACGAGGTGCTGG
CCGCCGTCCGCGACCAGGGCCTGAAGCTCGCCTTCGTTCTGGAGACCCACGCCCACGCCGACCACCTCTCGGCGGGCGAC
TACATCCGCAAGGCGACGGGCGCCGAGCTCGTCATCGGCGCCAACATCCGCGAGGTTCAGAAGACCTTCATCCCGATGTT
CGAGGCCGACGACGTCAGCCCCGACGGCCGGGTCTTCGACGTGCTGCTGGGCGAGGGCGACGTCCTGCGGATGGGCGAGA
TCGAGATCGGCGTGCTGCACACGCCCGGCCACACGCCCGCCTGCGTCACCTACCTGATCGGCGACGCCGCCTTCGTGGGC
GACACCCTGTTCATGCCGGACTACGGCACGGCGCGGGCGGACTTCCCGGGCGGCGACGCCGCGACGCTCTTCCGCTCGAT
CCGCAAGATCCTGGCGCTGCCGCCGCAGACCCGGATCTTCGTCGGCCACGACTACCTGCCCGAAGGCCGCGAGACCTTCC
GCTGGGAGACGACCGTGGCCGAGCAGCGGGCGGGCAACGTCCACGTCCACGACGGCGTCTCGGAGGCCGAGTTCGTGGCC
ATGCGGACGGCGCGCGACGCCACGCTGGCGGCGCCGACGCTGATCCTGCCCTCGCTGCAGGTGAACATCCGCGCCGGCGC
CCTGCCGCCGCCCACGCCGAGGGGTCACGTGTTCCTGCGGCTGCCGGTCACCACCCCCTGA

Upstream 100 bases:

>100_bases
CGGCGGATCAGGGCGCCGCCGGACGATCCGTCCATCCTGGGCTGCGCTTGTTATATTAGGAGGATCTAATATATTGGATC
TCGAAAGGGAGCCCACGAAC

Downstream 100 bases:

>100_bases
CATGGAGCCCTCGGCCTACTTCGCCGCGGTCGCCAGCGGAGCCCTCGTCGGCCTGCTGCTGACGGTGTTCGGCGGCGGCG
GATCGGTCCTGGCCACGCCG

Product: beta-lactamase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MRPHVQTFFDRATSTATHLVSDPATGVAAVVDPVLDFDPKSAKLSTRSADEVLAAVRDQGLKLAFVLETHAHADHLSAGD
YIRKATGAELVIGANIREVQKTFIPMFEADDVSPDGRVFDVLLGEGDVLRMGEIEIGVLHTPGHTPACVTYLIGDAAFVG
DTLFMPDYGTARADFPGGDAATLFRSIRKILALPPQTRIFVGHDYLPEGRETFRWETTVAEQRAGNVHVHDGVSEAEFVA
MRTARDATLAAPTLILPSLQVNIRAGALPPPTPRGHVFLRLPVTTP

Sequences:

>Translated_286_residues
MRPHVQTFFDRATSTATHLVSDPATGVAAVVDPVLDFDPKSAKLSTRSADEVLAAVRDQGLKLAFVLETHAHADHLSAGD
YIRKATGAELVIGANIREVQKTFIPMFEADDVSPDGRVFDVLLGEGDVLRMGEIEIGVLHTPGHTPACVTYLIGDAAFVG
DTLFMPDYGTARADFPGGDAATLFRSIRKILALPPQTRIFVGHDYLPEGRETFRWETTVAEQRAGNVHVHDGVSEAEFVA
MRTARDATLAAPTLILPSLQVNIRAGALPPPTPRGHVFLRLPVTTP
>Mature_286_residues
MRPHVQTFFDRATSTATHLVSDPATGVAAVVDPVLDFDPKSAKLSTRSADEVLAAVRDQGLKLAFVLETHAHADHLSAGD
YIRKATGAELVIGANIREVQKTFIPMFEADDVSPDGRVFDVLLGEGDVLRMGEIEIGVLHTPGHTPACVTYLIGDAAFVG
DTLFMPDYGTARADFPGGDAATLFRSIRKILALPPQTRIFVGHDYLPEGRETFRWETTVAEQRAGNVHVHDGVSEAEFVA
MRTARDATLAAPTLILPSLQVNIRAGALPPPTPRGHVFLRLPVTTP

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=269, Percent_Identity=28.996282527881, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI14150041, Length=163, Percent_Identity=28.2208588957055, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787158, Length=199, Percent_Identity=31.6582914572864, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17538952, Length=267, Percent_Identity=28.8389513108614, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI221330176, Length=269, Percent_Identity=31.5985130111524, Blast_Score=117, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 30833; Mature: 30833

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPHVQTFFDRATSTATHLVSDPATGVAAVVDPVLDFDPKSAKLSTRSADEVLAAVRDQG
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHCCC
LKLAFVLETHAHADHLSAGDYIRKATGAELVIGANIREVQKTFIPMFEADDVSPDGRVFD
CEEEEEEECCCCCCCCCCCHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCEEE
VLLGEGDVLRMGEIEIGVLHTPGHTPACVTYLIGDAAFVGDTLFMPDYGTARADFPGGDA
EEECCCCEEEECCEEEEEEECCCCCHHHHHHHHHCHHHHCCEEECCCCCCCCCCCCCCHH
ATLFRSIRKILALPPQTRIFVGHDYLPEGRETFRWETTVAEQRAGNVHVHDGVSEAEFVA
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHEEEEHHHHHHCCCCEEEECCCCCHHEEE
MRTARDATLAAPTLILPSLQVNIRAGALPPPTPRGHVFLRLPVTTP
EHHCCCCHHCCCEEEECCEEEEEEECCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MRPHVQTFFDRATSTATHLVSDPATGVAAVVDPVLDFDPKSAKLSTRSADEVLAAVRDQG
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHCCC
LKLAFVLETHAHADHLSAGDYIRKATGAELVIGANIREVQKTFIPMFEADDVSPDGRVFD
CEEEEEEECCCCCCCCCCCHHHHHCCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCEEE
VLLGEGDVLRMGEIEIGVLHTPGHTPACVTYLIGDAAFVGDTLFMPDYGTARADFPGGDA
EEECCCCEEEECCEEEEEEECCCCCHHHHHHHHHCHHHHCCEEECCCCCCCCCCCCCCHH
ATLFRSIRKILALPPQTRIFVGHDYLPEGRETFRWETTVAEQRAGNVHVHDGVSEAEFVA
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHEEEEHHHHHHCCCCEEEECCCCCHHEEE
MRTARDATLAAPTLILPSLQVNIRAGALPPPTPRGHVFLRLPVTTP
EHHCCCCHHCCCEEEECCEEEEEEECCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]