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The map label for this gene is mcpB [H]

Identifier: 197104198

GI number: 197104198

Start: 803383

End: 804879

Strand: Direct

Name: mcpB [H]

Synonym: PHZ_c0732

Alternate gene names: 197104198

Gene position: 803383-804879 (Clockwise)

Preceding gene: 197104197

Following gene: 197104200

Centisome position: 20.1

GC content: 74.01

Gene sequence:

>1497_bases
ATGCTCGTGAGTGACGCGTACGCGATCGGCCAGCGCCTGGATTTCATCGGCTTGGATGCGGAGACGCGCGCCGCGCTGGC
CCGGCTTCAGCCGTTCATCGGCGAGCACATCGGCCCGGCGCTCGATGCGTTCTACACGCGGGTGAAGGCGACGCCCGAGG
TCCGCCGCTTCTTCCGCGACGACAGCCACATCGCCGGCGCGCACGCCCGCCAGGGCGACCACTGGCGGATCATCGCGAGC
GGCAAGTTCGACGAAAGCTATGTGCGCGGCGTCCGCACCATCGGCGAGACCCACGCCCGCATCGGCCTGGAGCCGCGCTG
GTACATCGCCGGCTACGCCCTGATCCTCGAGCGCCTGCTGCGGGACCTCATCGACGAGCGCTGGGGCCGCCGCGGCCTTC
TGGCGGGCCGTCGGGGGGCGGAAGAGACCGGCGCCGCGGCCGGGGCCCTGGTGAAGGCCGTCCTGCTCGACATGGACTTC
GCCATCTCGATCTACCTGGAGACCCTCGAGGCCGAGCGCCGGCGGCTGGAAGCCGAGCGCGAGGCGGCCCAACAGCGGCA
GGCCGAGATGGTGGCGGCGCTGGAGGCGGCGCTGGCCCGCGTGTCGCGCGGCGACCTTCGCGCCCGCATCGAGGCGTCCG
CCCCCGAGTTCGAGACGGTCAGCGCCGACTTCAACTCCGCAATCTCGGCGCTGGAGCAGGCGGTGGCCGGGGCGGCCGCG
GCGGCGTCCGGCGTCTCGCAAGGCGTGGCGCAGATCGGCGGCGCCGCCGACCAGCTCTCGCAGCGCACCGAGCAGCAGGC
CGCCAGCCTGGAGGAGACCGCCGCGGCGCTGGAGGAGATCACCGTCGCCGTCCGCCGCAGCGCCGAGGGCGCCCAGGAGG
CTGCCCGCTTCGTCGCCGCCGCCAAGGGCGAGGCCGACGAGTCCGCCCAGGTCGTGCGCCAGGCCGTGGCCGCCATGGAC
GAGATCGACGGCTCGTCGCGCAAGATCGGCCAGATCATCGGGGTGATCGACGAGATCGCCTTCCAGACCAACCTGCTGGC
CCTGAACGCCGGGGTCGAGGCCGCCCGCGCCGGCGACGCCGGCCGCGGCTTCGCCGTCGTCGCCTCGGAGGTGCGGGCCC
TGGCCCAGCGCTCGGCCGACGCCGCCAAGGAGATCGAGGGGCTGATCGGGGAGTCCACCCGTCAGGTGAAGACCGGCGTG
CAGCTGGTCGGCCGCACGGGCGAGGCGCTGGCCGCCATCGTCGAGCGCATCGGCTCCATCGACCGGCTGGTGGGCGAGAC
CGCCGCCTCGGCCCAGGAGCAGGCCCGCGGCCTCAACGAGGTGAACGTGGCCGTCGCCCAGATGGACCAGATCACCCAGC
AGAACGCCGCCATGGTCGACGAGACCACGGCCGCCACCCGGGCCCTGCACGCCCAGGTGGACGATCTGGCCGGGACGATG
GGCTCCTTCACCGTGGCCGGCGCCGACCCGAGGGCGCGGCTGCGGGCGGTCGCCTAG

Upstream 100 bases:

>100_bases
TTGATTTCGGTCAAGCTTGGCTGTGGCGCATGGCCGCAGCGGGCGGCAAGGCGGCGTTAACGGACGGCCGGCTCTTAAGA
CCTCACAACAAGTGGGGTTT

Downstream 100 bases:

>100_bases
ATCCGGCGCCTAGATCCGGCGCCTAGATCTGGCGCTCGAGGCCGGCCCAGTAGGGCTCGCGCAGCTTGCGCTTGAAGATC
TTGCCCGAGTCCTCGCGCGG

Product: methyl-accepting chemotaxis protein McpB

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MLVSDAYAIGQRLDFIGLDAETRAALARLQPFIGEHIGPALDAFYTRVKATPEVRRFFRDDSHIAGAHARQGDHWRIIAS
GKFDESYVRGVRTIGETHARIGLEPRWYIAGYALILERLLRDLIDERWGRRGLLAGRRGAEETGAAAGALVKAVLLDMDF
AISIYLETLEAERRRLEAEREAAQQRQAEMVAALEAALARVSRGDLRARIEASAPEFETVSADFNSAISALEQAVAGAAA
AASGVSQGVAQIGGAADQLSQRTEQQAASLEETAAALEEITVAVRRSAEGAQEAARFVAAAKGEADESAQVVRQAVAAMD
EIDGSSRKIGQIIGVIDEIAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAQRSADAAKEIEGLIGESTRQVKTGV
QLVGRTGEALAAIVERIGSIDRLVGETAASAQEQARGLNEVNVAVAQMDQITQQNAAMVDETTAATRALHAQVDDLAGTM
GSFTVAGADPRARLRAVA

Sequences:

>Translated_498_residues
MLVSDAYAIGQRLDFIGLDAETRAALARLQPFIGEHIGPALDAFYTRVKATPEVRRFFRDDSHIAGAHARQGDHWRIIAS
GKFDESYVRGVRTIGETHARIGLEPRWYIAGYALILERLLRDLIDERWGRRGLLAGRRGAEETGAAAGALVKAVLLDMDF
AISIYLETLEAERRRLEAEREAAQQRQAEMVAALEAALARVSRGDLRARIEASAPEFETVSADFNSAISALEQAVAGAAA
AASGVSQGVAQIGGAADQLSQRTEQQAASLEETAAALEEITVAVRRSAEGAQEAARFVAAAKGEADESAQVVRQAVAAMD
EIDGSSRKIGQIIGVIDEIAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAQRSADAAKEIEGLIGESTRQVKTGV
QLVGRTGEALAAIVERIGSIDRLVGETAASAQEQARGLNEVNVAVAQMDQITQQNAAMVDETTAATRALHAQVDDLAGTM
GSFTVAGADPRARLRAVA
>Mature_498_residues
MLVSDAYAIGQRLDFIGLDAETRAALARLQPFIGEHIGPALDAFYTRVKATPEVRRFFRDDSHIAGAHARQGDHWRIIAS
GKFDESYVRGVRTIGETHARIGLEPRWYIAGYALILERLLRDLIDERWGRRGLLAGRRGAEETGAAAGALVKAVLLDMDF
AISIYLETLEAERRRLEAEREAAQQRQAEMVAALEAALARVSRGDLRARIEASAPEFETVSADFNSAISALEQAVAGAAA
AASGVSQGVAQIGGAADQLSQRTEQQAASLEETAAALEEITVAVRRSAEGAQEAARFVAAAKGEADESAQVVRQAVAAMD
EIDGSSRKIGQIIGVIDEIAFQTNLLALNAGVEAARAGDAGRGFAVVASEVRALAQRSADAAKEIEGLIGESTRQVKTGV
QLVGRTGEALAAIVERIGSIDRLVGETAASAQEQARGLNEVNVAVAQMDQITQQNAAMVDETTAATRALHAQVDDLAGTM
GSFTVAGADPRARLRAVA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=270, Percent_Identity=46.6666666666667, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI1787690, Length=299, Percent_Identity=41.4715719063545, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI2367378, Length=214, Percent_Identity=51.4018691588785, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1788195, Length=212, Percent_Identity=50.9433962264151, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789453, Length=228, Percent_Identity=36.8421052631579, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 52714; Mature: 52714

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSDAYAIGQRLDFIGLDAETRAALARLQPFIGEHIGPALDAFYTRVKATPEVRRFFRD
CCCCHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHCC
DSHIAGAHARQGDHWRIIASGKFDESYVRGVRTIGETHARIGLEPRWYIAGYALILERLL
CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RDLIDERWGRRGLLAGRRGAEETGAAAGALVKAVLLDMDFAISIYLETLEAERRRLEAER
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAAQQRQAEMVAALEAALARVSRGDLRARIEASAPEFETVSADFNSAISALEQAVAGAAA
HHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AASGVSQGVAQIGGAADQLSQRTEQQAASLEETAAALEEITVAVRRSAEGAQEAARFVAA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AKGEADESAQVVRQAVAAMDEIDGSSRKIGQIIGVIDEIAFQTNLLALNAGVEAARAGDA
HCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCC
GRGFAVVASEVRALAQRSADAAKEIEGLIGESTRQVKTGVQLVGRTGEALAAIVERIGSI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DRLVGETAASAQEQARGLNEVNVAVAQMDQITQQNAAMVDETTAATRALHAQVDDLAGTM
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSFTVAGADPRARLRAVA
CCEEEECCCHHHHHHCCC
>Mature Secondary Structure
MLVSDAYAIGQRLDFIGLDAETRAALARLQPFIGEHIGPALDAFYTRVKATPEVRRFFRD
CCCCHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHCC
DSHIAGAHARQGDHWRIIASGKFDESYVRGVRTIGETHARIGLEPRWYIAGYALILERLL
CCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RDLIDERWGRRGLLAGRRGAEETGAAAGALVKAVLLDMDFAISIYLETLEAERRRLEAER
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAAQQRQAEMVAALEAALARVSRGDLRARIEASAPEFETVSADFNSAISALEQAVAGAAA
HHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AASGVSQGVAQIGGAADQLSQRTEQQAASLEETAAALEEITVAVRRSAEGAQEAARFVAA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AKGEADESAQVVRQAVAAMDEIDGSSRKIGQIIGVIDEIAFQTNLLALNAGVEAARAGDA
HCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCC
GRGFAVVASEVRALAQRSADAAKEIEGLIGESTRQVKTGVQLVGRTGEALAAIVERIGSI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DRLVGETAASAQEQARGLNEVNVAVAQMDQITQQNAAMVDETTAATRALHAQVDDLAGTM
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSFTVAGADPRARLRAVA
CCEEEECCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]