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The map label for this gene is zraS [C]

Identifier: 197104163

GI number: 197104163

Start: 762328

End: 764223

Strand: Direct

Name: zraS [C]

Synonym: PHZ_c0697

Alternate gene names: 197104163

Gene position: 762328-764223 (Clockwise)

Preceding gene: 197104162

Following gene: 197104165

Centisome position: 19.08

GC content: 73.36

Gene sequence:

>1896_bases
ATGACCGCCCAGCGCGCCCGGCTGATGATGGTGGACGACGAGGCCGACATCCTCGTCGCCCTGCAGGATCTGTTCGAGAC
GACCTACGACGTCAGCGCCTTCACCTCGCCCGCCGAGGCGCTGGAAGCCCTGGCCGGCGGCCTCGACCCCGCGGTGATCG
TCTCGGACCAGCGGATGCCGGGCATGCCGGGCGACCGGTTCCTGGCCGAGGCCCGCAGGCTGTGCGACGCCGGGGCCATC
CTGCTCACCGGCTACGCCGACCTGAGCGCGGTCACCGCCGCCCTGAACGGCGGCGGGATCGTCGGCTACGTGCCCAAGCC
CTGGGAGCCCGACGCCCTGAAGGCCATGGTGGCCGGGGCGGTCGAACAGCACCACCTGCGCCGCGCTCTAGGGCAGGAGC
AGGCGCTGCTGCACGGCCTGATGGACCATCTGCCCTACGCCGTGGCGTTCAAGGACGCGCAGGGCCGCTTCGTCCATCTC
AACGAGCGCAAGGCGGGCGAGTTCGGCCGCGCCGCCGCGGCCTGCGTCGGCCTGACGGAGGCCGAGCTCGGCGGCGTCGT
CCGCGCCGAGGAGCGGCAGGCGATCGCCGAGCGCCGGGCTCTGCAGGTTGTCGAGGAACGGCCCGGACCGGCGGGCCCGT
CCTGGATCCAGGTCGAGTACGTGCCGCTCCTGGGGCGTGCGGGCGAGGTCGAGACGCTCGTGGTGATGGAGCGCGACATC
ACCGAGCAGCGCCTGGCCGAGCAGCAGCTGCGCCAGTCGGACAAGCTGCGCGCGCTGGGCACGCTGGCCGGCGGCGTGGC
CCACGACTTCAACAACCTGCTGACCGCCATCGTCGGCAGCCTGGAGCTGGCGAGCAAGCGGCTGGACCGCGATCCGGAGA
CCGTGCGCCGCTACCTCGACAACGCCGCCCTGGCGGCGCAGCGCGGCGCATCCCTGACCCAACGGCTGCTGGGCTTCAGC
CGCCGGACCGACAGCCGCCTGGCGGTGGTGGATGTCGCCGCCGCCATGACCGGCATGCGCGACCTGCTGTCCCGCACGCT
GGGCGGGGGCGTCGAGGTGGAATGGCGGATCGCCGCCGACCTGTGGCCGACGTCGGTGGAGCCGGACCAGCTCGAGGTCG
CGATCCTGAACCTGGCGATCAACGCGCGCGACGCCATGCCGGACGGCGGCGTCATCACCATCGCGGCGCGCAACGTCAGC
CTGCCTGCGGAGGCCGACCTGGAGCGGGGCCTTACGGCCGGCGACTACGTCATGCTGGTCATCGCCGACACGGGCGAGGG
GATGCCGCCCGAGCTGCTGGAACGGGTGCTGGAGCCCTTCTTCACGACCAAGCCGGTGGGCAAGGGCACGGGCCTGGGCC
TGCCGATGGTCTACGGCTTCGCGCAGCGTTCGGGCGGGACCCTGTCGATCCGCAGCACGCCGGGGCAGGGCACGGAGGTC
GTCATGTACCTGCCGCGCGCCGGGGAGGCGGACGAGCCGCTTCCGGAGTCGGCGCCGGCCGCTGTCCGGCGGGGACCGCG
CGCGCGCATCCTGGTGCTGGACGACGAGCCGGGCGTGCGGTCGGTGACCGCCGCCAGCCTGCGGGACCTGGGCCATGAGG
TGGTGGAAGCCGCCGACGGGCCGGCGGCGCTGGCGATCCTGCAGGGCGGCCGGGAGGTCGACCTCGCGGTGGTGGATTTC
GCCATGCCCGGCATGAACGGGCTGGAGTTCGTCGAGAAGGCCCGACGGCTGGCGGCCGGCCTGCCGGTGATCCTGCTCAC
CGGCTACGTCGACGTCGAGGCGGCCCCCGACGACGTCATGGTGCTGCACAAGCCGTTCACCGCCGCCACGCTCGAAGCCG
CCGTTGCGGCCGCGCTCGCGACGGAGTTCGCCTCGCGGGAAGGCCTGACGCTCTAG

Upstream 100 bases:

>100_bases
CTTTTTCCGTCGTGCGGGCCCATGACGGCGCGATCTCGGTGGACGAGGGGCCGCTGGGCGGCGCACGCTTCGTCATCGAC
CTGCCGGCGGGAGGCGCCGC

Downstream 100 bases:

>100_bases
GCCGGCGCCGCGGCCCGTCGACCCGCTGCTTCCGCGCCGGCGTCGATGGCGGACCGGAGCTCGGAGACGAGCTGCGGCAG
GAGCCGCGCCCGCGCGTCGG

Product: sensor histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 631; Mature: 630

Protein sequence:

>631_residues
MTAQRARLMMVDDEADILVALQDLFETTYDVSAFTSPAEALEALAGGLDPAVIVSDQRMPGMPGDRFLAEARRLCDAGAI
LLTGYADLSAVTAALNGGGIVGYVPKPWEPDALKAMVAGAVEQHHLRRALGQEQALLHGLMDHLPYAVAFKDAQGRFVHL
NERKAGEFGRAAAACVGLTEAELGGVVRAEERQAIAERRALQVVEERPGPAGPSWIQVEYVPLLGRAGEVETLVVMERDI
TEQRLAEQQLRQSDKLRALGTLAGGVAHDFNNLLTAIVGSLELASKRLDRDPETVRRYLDNAALAAQRGASLTQRLLGFS
RRTDSRLAVVDVAAAMTGMRDLLSRTLGGGVEVEWRIAADLWPTSVEPDQLEVAILNLAINARDAMPDGGVITIAARNVS
LPAEADLERGLTAGDYVMLVIADTGEGMPPELLERVLEPFFTTKPVGKGTGLGLPMVYGFAQRSGGTLSIRSTPGQGTEV
VMYLPRAGEADEPLPESAPAAVRRGPRARILVLDDEPGVRSVTAASLRDLGHEVVEAADGPAALAILQGGREVDLAVVDF
AMPGMNGLEFVEKARRLAAGLPVILLTGYVDVEAAPDDVMVLHKPFTAATLEAAVAAALATEFASREGLTL

Sequences:

>Translated_631_residues
MTAQRARLMMVDDEADILVALQDLFETTYDVSAFTSPAEALEALAGGLDPAVIVSDQRMPGMPGDRFLAEARRLCDAGAI
LLTGYADLSAVTAALNGGGIVGYVPKPWEPDALKAMVAGAVEQHHLRRALGQEQALLHGLMDHLPYAVAFKDAQGRFVHL
NERKAGEFGRAAAACVGLTEAELGGVVRAEERQAIAERRALQVVEERPGPAGPSWIQVEYVPLLGRAGEVETLVVMERDI
TEQRLAEQQLRQSDKLRALGTLAGGVAHDFNNLLTAIVGSLELASKRLDRDPETVRRYLDNAALAAQRGASLTQRLLGFS
RRTDSRLAVVDVAAAMTGMRDLLSRTLGGGVEVEWRIAADLWPTSVEPDQLEVAILNLAINARDAMPDGGVITIAARNVS
LPAEADLERGLTAGDYVMLVIADTGEGMPPELLERVLEPFFTTKPVGKGTGLGLPMVYGFAQRSGGTLSIRSTPGQGTEV
VMYLPRAGEADEPLPESAPAAVRRGPRARILVLDDEPGVRSVTAASLRDLGHEVVEAADGPAALAILQGGREVDLAVVDF
AMPGMNGLEFVEKARRLAAGLPVILLTGYVDVEAAPDDVMVLHKPFTAATLEAAVAAALATEFASREGLTL
>Mature_630_residues
TAQRARLMMVDDEADILVALQDLFETTYDVSAFTSPAEALEALAGGLDPAVIVSDQRMPGMPGDRFLAEARRLCDAGAIL
LTGYADLSAVTAALNGGGIVGYVPKPWEPDALKAMVAGAVEQHHLRRALGQEQALLHGLMDHLPYAVAFKDAQGRFVHLN
ERKAGEFGRAAAACVGLTEAELGGVVRAEERQAIAERRALQVVEERPGPAGPSWIQVEYVPLLGRAGEVETLVVMERDIT
EQRLAEQQLRQSDKLRALGTLAGGVAHDFNNLLTAIVGSLELASKRLDRDPETVRRYLDNAALAAQRGASLTQRLLGFSR
RTDSRLAVVDVAAAMTGMRDLLSRTLGGGVEVEWRIAADLWPTSVEPDQLEVAILNLAINARDAMPDGGVITIAARNVSL
PAEADLERGLTAGDYVMLVIADTGEGMPPELLERVLEPFFTTKPVGKGTGLGLPMVYGFAQRSGGTLSIRSTPGQGTEVV
MYLPRAGEADEPLPESAPAAVRRGPRARILVLDDEPGVRSVTAASLRDLGHEVVEAADGPAALAILQGGREVDLAVVDFA
MPGMNGLEFVEKARRLAAGLPVILLTGYVDVEAAPDDVMVLHKPFTAATLEAAVAAALATEFASREGLTL

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=260, Percent_Identity=29.2307692307692, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081816, Length=234, Percent_Identity=30.3418803418803, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788549, Length=260, Percent_Identity=28.8461538461538, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI48994928, Length=541, Percent_Identity=22.550831792976, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=185, Percent_Identity=29.7297297297297, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=230, Percent_Identity=31.7391304347826, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790300, Length=253, Percent_Identity=28.4584980237154, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67003; Mature: 66872

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQRARLMMVDDEADILVALQDLFETTYDVSAFTSPAEALEALAGGLDPAVIVSDQRMP
CCCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCEEEEECCCCC
GMPGDRFLAEARRLCDAGAILLTGYADLSAVTAALNGGGIVGYVPKPWEPDALKAMVAGA
CCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHH
VEQHHLRRALGQEQALLHGLMDHLPYAVAFKDAQGRFVHLNERKAGEFGRAAAACVGLTE
HHHHHHHHHHCHHHHHHHHHHHHCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHCCCH
AELGGVVRAEERQAIAERRALQVVEERPGPAGPSWIQVEYVPLLGRAGEVETLVVMERDI
HHHCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCEEEEEEECCC
TEQRLAEQQLRQSDKLRALGTLAGGVAHDFNNLLTAIVGSLELASKRLDRDPETVRRYLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
NAALAAQRGASLTQRLLGFSRRTDSRLAVVDVAAAMTGMRDLLSRTLGGGVEVEWRIAAD
HHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
LWPTSVEPDQLEVAILNLAINARDAMPDGGVITIAARNVSLPAEADLERGLTAGDYVMLV
CCCCCCCCCCEEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCEEEEE
IADTGEGMPPELLERVLEPFFTTKPVGKGTGLGLPMVYGFAQRSGGTLSIRSTPGQGTEV
EECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEE
VMYLPRAGEADEPLPESAPAAVRRGPRARILVLDDEPGVRSVTAASLRDLGHEVVEAADG
EEECCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
PAALAILQGGREVDLAVVDFAMPGMNGLEFVEKARRLAAGLPVILLTGYVDVEAAPDDVM
CEEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECEEEEECCCCCEE
VLHKPFTAATLEAAVAAALATEFASREGLTL
EEECCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TAQRARLMMVDDEADILVALQDLFETTYDVSAFTSPAEALEALAGGLDPAVIVSDQRMP
CCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCEEEEECCCCC
GMPGDRFLAEARRLCDAGAILLTGYADLSAVTAALNGGGIVGYVPKPWEPDALKAMVAGA
CCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHH
VEQHHLRRALGQEQALLHGLMDHLPYAVAFKDAQGRFVHLNERKAGEFGRAAAACVGLTE
HHHHHHHHHHCHHHHHHHHHHHHCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHCCCH
AELGGVVRAEERQAIAERRALQVVEERPGPAGPSWIQVEYVPLLGRAGEVETLVVMERDI
HHHCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCEEEEEEECCC
TEQRLAEQQLRQSDKLRALGTLAGGVAHDFNNLLTAIVGSLELASKRLDRDPETVRRYLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
NAALAAQRGASLTQRLLGFSRRTDSRLAVVDVAAAMTGMRDLLSRTLGGGVEVEWRIAAD
HHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
LWPTSVEPDQLEVAILNLAINARDAMPDGGVITIAARNVSLPAEADLERGLTAGDYVMLV
CCCCCCCCCCEEEEEEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCEEEEE
IADTGEGMPPELLERVLEPFFTTKPVGKGTGLGLPMVYGFAQRSGGTLSIRSTPGQGTEV
EECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEE
VMYLPRAGEADEPLPESAPAAVRRGPRARILVLDDEPGVRSVTAASLRDLGHEVVEAADG
EEECCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
PAALAILQGGREVDLAVVDFAMPGMNGLEFVEKARRLAAGLPVILLTGYVDVEAAPDDVM
CEEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECEEEEECCCCCEE
VLHKPFTAATLEAAVAAALATEFASREGLTL
EEECCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA