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The map label for this gene is mcpA [H]

Identifier: 195952689

GI number: 195952689

Start: 270982

End: 272643

Strand: Direct

Name: mcpA [H]

Synonym: HY04AAS1_0311

Alternate gene names: 195952689

Gene position: 270982-272643 (Clockwise)

Preceding gene: 195952688

Following gene: 195952690

Centisome position: 17.38

GC content: 32.67

Gene sequence:

>1662_bases
ATGAAATTTAAGACGAAAGTAAACATAAGGATAGTCTTGGCGCTTCTTTTCTTATGGATAGCTAGCACGGTGGCTTCACT
TTACAGCACTAGAGTATTATCTATAAAAGCTGCAAAACAAACTGCCAACATAGCTGCAAACACTGTAAGGATAGGTTTAA
ACTCTGAAATGCTAAACGGAACTATGGCAAATAGAGAGTTTATATTAAAAGAGACAAAATATATAAAGGGTATAAAAGAT
GTTTATGTAATAAGAGGAGAAGCTGTAGACAAGCAGTTTGGACCCGGCTTTAAAAACGAGAATCCAAGAGATAGAATAGA
TGATGAAGTGCTTAAAGCGGGAAAGCCAATGTATGTTTTTGACGAAAATCTAAAAAACGCATCTTTTAGAATCACAATAC
CTTATATAGCAAGACCTTATAAAGGTATAAACTGTTTGCAGTGCCATCAGGTCAAAGAAGGCACGGTGTTGGGAGCTATA
ACTTTAAAATTGGATATGAACAAATTTAGAAACGTAGGTCTTTTTCTGGGTGCCATTATTTCATCGCTCTATTTAATTGT
AATAGTTTTGGTATTTTTTATAATGAGTAGGTTCTTTTCAAAATATATTTATGTTTTTTCTAAAATGGACACTTCTATAA
CACATTTGTCTAATGGCGATTTTTCTGATTCTTCAGGGGCTCTTGAAGCCTTGAAAAATGTTAACTTTAAAGATGAAATA
GGCAACATTATATCTTCATATAGAAATTTGGCTAACGTGCTAAAAACTATTTTTGGTGAACTTTTTGATTTAGCTAAACA
TCTGTCTCAAGGTGATCTAAGATATAGAATATCGTCAAACTTCTCTGGTGAATTTGAAAATATCAAAAACAATCTAAACA
GTGCCATAGATGAACTTTCTAAAAGCTTAAAGAAAGCTGTTGATAGTTTTAATGAAATAGCTTCACATGTAGAGTCTTTT
GAAGGGGATATAAAAGATATAACAGAAAACATATCTTTACAAAACCAAGAGATTAACGCTATATCCTCTATGATAGAGGA
GTTTTCCGCTACTTTAAAGGATATATCAAATAACACAGAAAAACTTGATAATTCTACAAAATCTATGAATGATTCTATAG
CTTCTAGCAAAGAAAAGATGGAAACCTTAAGTCAAGCTTCTTCAAAGATTATGTATTCTGGTAAAAGGATATCCGAATTT
ATAGAAAAAATAATAGATATCTCAGAGCAAACAAATCTTTTAGCCTTAAACGCTGCAATAGAGGCTGCCCGTGCTGGTGA
ACAAGGAAGAGGGTTTGCGGTAGTAGCCGATGAGGTGAGAAAACTAGCAAACAACACTCAAGAAGCTGCTTCTGAAATAA
GCTCTATGGTAAACGAAGTTATAAAAGCTATCGAAGATACGGTAAAAGCTACACAAGAATCTACAGAAGAGTTTAAAACT
ATAATAACTGGTTTTGAAAGTATGTCTATTCTCATAAGCCAGATAGCGAAAGCTATAGAGCAGCAAAACGTGGCTTTAAA
TGCAATAGTAAATGCTGTATTTAACATAAAGGAATCTTCGGAAAGAAACACCGCAAAGATTTTAAATATAAAAACCAAAT
CAGAGTTTGTAAAAAACATTGTAGATAGCTCAAAGCAATTTATTAACAGATTTAAGCTATGA

Upstream 100 bases:

>100_bases
AAAACCTTCAAAATATGATACTTGATTTATTGAAATAAATTGTCATTGACAATAATCAAATCATTGACAATAATCAAATT
TTTAGTGTAAAATTATCTCT

Downstream 100 bases:

>100_bases
TTGATGCTTTTAACTCTTCTTGGGACAGCGATAAAATAAACGAAAACCAATGGGAAGAGACAGCGCAAGGTATAGATGAA
TATATAGAGACCTCTCATTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MKFKTKVNIRIVLALLFLWIASTVASLYSTRVLSIKAAKQTANIAANTVRIGLNSEMLNGTMANREFILKETKYIKGIKD
VYVIRGEAVDKQFGPGFKNENPRDRIDDEVLKAGKPMYVFDENLKNASFRITIPYIARPYKGINCLQCHQVKEGTVLGAI
TLKLDMNKFRNVGLFLGAIISSLYLIVIVLVFFIMSRFFSKYIYVFSKMDTSITHLSNGDFSDSSGALEALKNVNFKDEI
GNIISSYRNLANVLKTIFGELFDLAKHLSQGDLRYRISSNFSGEFENIKNNLNSAIDELSKSLKKAVDSFNEIASHVESF
EGDIKDITENISLQNQEINAISSMIEEFSATLKDISNNTEKLDNSTKSMNDSIASSKEKMETLSQASSKIMYSGKRISEF
IEKIIDISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLANNTQEAASEISSMVNEVIKAIEDTVKATQESTEEFKT
IITGFESMSILISQIAKAIEQQNVALNAIVNAVFNIKESSERNTAKILNIKTKSEFVKNIVDSSKQFINRFKL

Sequences:

>Translated_553_residues
MKFKTKVNIRIVLALLFLWIASTVASLYSTRVLSIKAAKQTANIAANTVRIGLNSEMLNGTMANREFILKETKYIKGIKD
VYVIRGEAVDKQFGPGFKNENPRDRIDDEVLKAGKPMYVFDENLKNASFRITIPYIARPYKGINCLQCHQVKEGTVLGAI
TLKLDMNKFRNVGLFLGAIISSLYLIVIVLVFFIMSRFFSKYIYVFSKMDTSITHLSNGDFSDSSGALEALKNVNFKDEI
GNIISSYRNLANVLKTIFGELFDLAKHLSQGDLRYRISSNFSGEFENIKNNLNSAIDELSKSLKKAVDSFNEIASHVESF
EGDIKDITENISLQNQEINAISSMIEEFSATLKDISNNTEKLDNSTKSMNDSIASSKEKMETLSQASSKIMYSGKRISEF
IEKIIDISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLANNTQEAASEISSMVNEVIKAIEDTVKATQESTEEFKT
IITGFESMSILISQIAKAIEQQNVALNAIVNAVFNIKESSERNTAKILNIKTKSEFVKNIVDSSKQFINRFKL
>Mature_553_residues
MKFKTKVNIRIVLALLFLWIASTVASLYSTRVLSIKAAKQTANIAANTVRIGLNSEMLNGTMANREFILKETKYIKGIKD
VYVIRGEAVDKQFGPGFKNENPRDRIDDEVLKAGKPMYVFDENLKNASFRITIPYIARPYKGINCLQCHQVKEGTVLGAI
TLKLDMNKFRNVGLFLGAIISSLYLIVIVLVFFIMSRFFSKYIYVFSKMDTSITHLSNGDFSDSSGALEALKNVNFKDEI
GNIISSYRNLANVLKTIFGELFDLAKHLSQGDLRYRISSNFSGEFENIKNNLNSAIDELSKSLKKAVDSFNEIASHVESF
EGDIKDITENISLQNQEINAISSMIEEFSATLKDISNNTEKLDNSTKSMNDSIASSKEKMETLSQASSKIMYSGKRISEF
IEKIIDISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLANNTQEAASEISSMVNEVIKAIEDTVKATQESTEEFKT
IITGFESMSILISQIAKAIEQQNVALNAIVNAVFNIKESSERNTAKILNIKTKSEFVKNIVDSSKQFINRFKL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=263, Percent_Identity=28.1368821292776, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1788195, Length=256, Percent_Identity=27.34375, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788194, Length=228, Percent_Identity=28.0701754385965, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789453, Length=492, Percent_Identity=23.9837398373984, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787690, Length=362, Percent_Identity=24.3093922651934, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 61673; Mature: 61673

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKTKVNIRIVLALLFLWIASTVASLYSTRVLSIKAAKQTANIAANTVRIGLNSEMLNG
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHEEEECCCHHHHCC
TMANREFILKETKYIKGIKDVYVIRGEAVDKQFGPGFKNENPRDRIDDEVLKAGKPMYVF
HHCCHHHHHHHHHHHCCCHHHEEEECCHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEE
DENLKNASFRITIPYIARPYKGINCLQCHQVKEGTVLGAITLKLDMNKFRNVGLFLGAII
CCCCCCCEEEEEECHHCCCCCCCCHHHHHCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHH
SSLYLIVIVLVFFIMSRFFSKYIYVFSKMDTSITHLSNGDFSDSSGALEALKNVNFKDEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHCCCCHHHH
GNIISSYRNLANVLKTIFGELFDLAKHLSQGDLRYRISSNFSGEFENIKNNLNSAIDELS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
KSLKKAVDSFNEIASHVESFEGDIKDITENISLQNQEINAISSMIEEFSATLKDISNNTE
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
KLDNSTKSMNDSIASSKEKMETLSQASSKIMYSGKRISEFIEKIIDISEQTNLLALNAAI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEHHHHH
EAARAGEQGRGFAVVADEVRKLANNTQEAASEISSMVNEVIKAIEDTVKATQESTEEFKT
HHHHCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IITGFESMSILISQIAKAIEQQNVALNAIVNAVFNIKESSERNTAKILNIKTKSEFVKNI
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHH
VDSSKQFINRFKL
HHHHHHHHHHHCC
>Mature Secondary Structure
MKFKTKVNIRIVLALLFLWIASTVASLYSTRVLSIKAAKQTANIAANTVRIGLNSEMLNG
CCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHEEEECCCHHHHCC
TMANREFILKETKYIKGIKDVYVIRGEAVDKQFGPGFKNENPRDRIDDEVLKAGKPMYVF
HHCCHHHHHHHHHHHCCCHHHEEEECCHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEE
DENLKNASFRITIPYIARPYKGINCLQCHQVKEGTVLGAITLKLDMNKFRNVGLFLGAII
CCCCCCCEEEEEECHHCCCCCCCCHHHHHCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHH
SSLYLIVIVLVFFIMSRFFSKYIYVFSKMDTSITHLSNGDFSDSSGALEALKNVNFKDEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHCCCCHHHH
GNIISSYRNLANVLKTIFGELFDLAKHLSQGDLRYRISSNFSGEFENIKNNLNSAIDELS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
KSLKKAVDSFNEIASHVESFEGDIKDITENISLQNQEINAISSMIEEFSATLKDISNNTE
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
KLDNSTKSMNDSIASSKEKMETLSQASSKIMYSGKRISEFIEKIIDISEQTNLLALNAAI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEHHHHH
EAARAGEQGRGFAVVADEVRKLANNTQEAASEISSMVNEVIKAIEDTVKATQESTEEFKT
HHHHCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IITGFESMSILISQIAKAIEQQNVALNAIVNAVFNIKESSERNTAKILNIKTKSEFVKNI
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHH
VDSSKQFINRFKL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]