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The map label for this gene is uidR [H]

Identifier: 194737268

GI number: 194737268

Start: 3194331

End: 3194927

Strand: Reverse

Name: uidR [H]

Synonym: SeSA_A3312

Alternate gene names: 194737268

Gene position: 3194927-3194331 (Counterclockwise)

Preceding gene: 194738213

Following gene: 194738362

Centisome position: 67.85

GC content: 49.75

Gene sequence:

>597_bases
ATGGAGAATAAACTTACCGAATCACTACCGACGCGGATGCGAATTTTACGCGCCGCCAGGCAGTGTTTTGCTGAAAACGG
TTTTCACAGTACATCAATGAAAACGATCTGTAAGGCCAGCGACATGAGCCCCGGCACACTCTATCATCACTTCCCCTCTA
AAGAGGCCCTGATTGAAGCCATTATTTTAGAAGATCAGGAAAGAGCACTAACCCATTTTCGTGAGCCGCTGGAGGGCGTT
GGGCTGGTGGATTATCTGGTGGAGTCAACTATTGCCGTCACGCGTGAAGACTGCGCGCAGCGGGCGTTGGTCGTAGAGAT
TATGGCTGAAGGGATGCGTAATCCTCAGGTCGCGGAAATGCTAACCAATAAATACCACACTATTATCGCCTCGCTGGTTG
CACGTTTTAACGATGCGCAGGCGAAGGGGGAAATTGGCGCCGATGTGGATAAAGAAATGGCGGCAAGGCTATTATTAGCT
ACCACGTATGGTGTTTTATCGGATAGCAGCTCTGCTGAGAATGCCCGGCACGTCAGTTTTGCGACGACGTTAAGAACTAT
GTTAACCGGGCTACTAAAATGCAACTCTGCAAGCTAG

Upstream 100 bases:

>100_bases
AGGGATATCATGAGGATCAAAGAAAATAGGATGAAGAGTAGGCGCCTGAAGTGCGCCCGGGTACACTGCCACCACGCAGA
GTGAAAAATGGGTCAACGTA

Downstream 100 bases:

>100_bases
TGTCGGTAAAAATACGCGTTCGTTTTATACGAGCGCGTTATCATTTAGTTTGCCTGATTATTTTTAGATGATGAAAATAA
TATTGTGGTAAGGGTTATTG

Product: transcriptional regulator UidR

Products: NA

Alternate protein names: Uid operon repressor [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MENKLTESLPTRMRILRAARQCFAENGFHSTSMKTICKASDMSPGTLYHHFPSKEALIEAIILEDQERALTHFREPLEGV
GLVDYLVESTIAVTREDCAQRALVVEIMAEGMRNPQVAEMLTNKYHTIIASLVARFNDAQAKGEIGADVDKEMAARLLLA
TTYGVLSDSSSAENARHVSFATTLRTMLTGLLKCNSAS

Sequences:

>Translated_198_residues
MENKLTESLPTRMRILRAARQCFAENGFHSTSMKTICKASDMSPGTLYHHFPSKEALIEAIILEDQERALTHFREPLEGV
GLVDYLVESTIAVTREDCAQRALVVEIMAEGMRNPQVAEMLTNKYHTIIASLVARFNDAQAKGEIGADVDKEMAARLLLA
TTYGVLSDSSSAENARHVSFATTLRTMLTGLLKCNSAS
>Mature_198_residues
MENKLTESLPTRMRILRAARQCFAENGFHSTSMKTICKASDMSPGTLYHHFPSKEALIEAIILEDQERALTHFREPLEGV
GLVDYLVESTIAVTREDCAQRALVVEIMAEGMRNPQVAEMLTNKYHTIIASLVARFNDAQAKGEIGADVDKEMAARLLLA
TTYGVLSDSSSAENARHVSFATTLRTMLTGLLKCNSAS

Specific function: Repressor for the uidRABC (gusRABC) operon [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787904, Length=192, Percent_Identity=62.5, Blast_Score=248, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21808; Mature: 21808

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKLTESLPTRMRILRAARQCFAENGFHSTSMKTICKASDMSPGTLYHHFPSKEALIEA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCCCHHHHHHH
IILEDQERALTHFREPLEGVGLVDYLVESTIAVTREDCAQRALVVEIMAEGMRNPQVAEM
HHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LTNKYHTIIASLVARFNDAQAKGEIGADVDKEMAARLLLATTYGVLSDSSSAENARHVSF
HHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ATTLRTMLTGLLKCNSAS
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MENKLTESLPTRMRILRAARQCFAENGFHSTSMKTICKASDMSPGTLYHHFPSKEALIEA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCCCHHHHHHH
IILEDQERALTHFREPLEGVGLVDYLVESTIAVTREDCAQRALVVEIMAEGMRNPQVAEM
HHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LTNKYHTIIASLVARFNDAQAKGEIGADVDKEMAARLLLATTYGVLSDSSSAENARHVSF
HHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ATTLRTMLTGLLKCNSAS
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]