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The map label for this gene is ccmH [H]

Identifier: 194736981

GI number: 194736981

Start: 2353171

End: 2354214

Strand: Reverse

Name: ccmH [H]

Synonym: SeSA_A2473

Alternate gene names: 194736981

Gene position: 2354214-2353171 (Counterclockwise)

Preceding gene: 194737651

Following gene: 194735390

Centisome position: 49.99

GC content: 65.9

Gene sequence:

>1044_bases
ATGAGACTGTTACCGGGCATGGTGATGCTGATGCTGGCGCTGGTTATCTCCGGGTCAGCGCGGGCGACCACCGACGTGAT
GCCGTTTAAAGATGAAGCGCAGGAGCAGCAGTTCCGCCAGCTCACGGAGCAGCTGCGCTGCCCGAAATGCCAGAACAACA
GCATTGCGGACTCGAACGCGATGATAGCCACCGACATGCGCCGCAGGGTGTATGACCTGATGCAGGAGGGGAAGAGCCGC
CAGGAAATCATCGATTACATGGTGGCGCGCTACGGCAACTTCGTCACCTACGACCCGCCGCTGACCCCGCTGACGGTGCT
GCTGTGGGTGCTGCCGCTGGCCGCCATCGTGGCGGGCGGGTGGATAATCGTTGCCCGCACGCGCCGGCGGGTGCGTATCA
GACAGGACGTCCTGGCTGACGCCATTCCTGCGGCGGGACCACGCGCAGGGGTGGGGGTGTATCTTCCGGGCGTGGTTATG
GCGCTGGTCGTGGCCGCCATCAGTTACTCACAGACCGGCAGCTATCAGCAGGTCAGGGCCTGGCAGCAGGCGACGGCGCA
GACGCCCGGGCTGCTGGCGCGGGCGCTGGACCCGCAGGCGCAGCCGCTGAATGAAGAGGAGATGGCGCGGCTGGCGCTGG
GGCTGCGCACCCGCCTGCAGAATGATGCCGGCAATGTTGAGGGCTGGCTCATGCTGGGACGCATCGGTATGGTACTGGGT
AATGCCGGTACCGCCACCGGGGCGTATGCGAACGCCTGTCGCCTGGACCCGAAAAACAGCGATGCGGCGCTGGGCTACGC
GGAGGCGCTGACGCGCTCGTCCGACCCGGAGGATAACCGCCGCGGCGGGGAGCTGCTGCGCCGGCTGGTGAGCCGCGACC
ACACGGATATCCGGGTGTTAAGCCTGTATGCGTTCAGCGCCTTTGAGCAGCAGCGCTTTGATGAGGCGGTGGCGGCCTGG
GAGATGATGCTGAAGTTACTGCCGGCGGGTGACGCCCGGCGGGCGGTGATAGAGCGCAGTATCCGGCTGGCGCAGGAGAA
ATAA

Upstream 100 bases:

>100_bases
GGGGGATTATCCGCTACCGCCATGCGGGCGATTTGAATGCCCGGGTATGGGAAAGTGAACTGAAACCGCTGTGGGACAGA
TACAGCCGGGAGGCGGCGCA

Downstream 100 bases:

>100_bases
TGCCCTGACGGCCCGGTGGCGTGGCGCCATCGGGCCTGGCTTGTTACTGCATTCCGCGTGTTTGTAAAAATAGAATGGTC
GCCGCGACGCGCGAGCGCAC

Product: cytochrome c-type biogenesis protein H2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MRLLPGMVMLMLALVISGSARATTDVMPFKDEAQEQQFRQLTEQLRCPKCQNNSIADSNAMIATDMRRRVYDLMQEGKSR
QEIIDYMVARYGNFVTYDPPLTPLTVLLWVLPLAAIVAGGWIIVARTRRRVRIRQDVLADAIPAAGPRAGVGVYLPGVVM
ALVVAAISYSQTGSYQQVRAWQQATAQTPGLLARALDPQAQPLNEEEMARLALGLRTRLQNDAGNVEGWLMLGRIGMVLG
NAGTATGAYANACRLDPKNSDAALGYAEALTRSSDPEDNRRGGELLRRLVSRDHTDIRVLSLYAFSAFEQQRFDEAVAAW
EMMLKLLPAGDARRAVIERSIRLAQEK

Sequences:

>Translated_347_residues
MRLLPGMVMLMLALVISGSARATTDVMPFKDEAQEQQFRQLTEQLRCPKCQNNSIADSNAMIATDMRRRVYDLMQEGKSR
QEIIDYMVARYGNFVTYDPPLTPLTVLLWVLPLAAIVAGGWIIVARTRRRVRIRQDVLADAIPAAGPRAGVGVYLPGVVM
ALVVAAISYSQTGSYQQVRAWQQATAQTPGLLARALDPQAQPLNEEEMARLALGLRTRLQNDAGNVEGWLMLGRIGMVLG
NAGTATGAYANACRLDPKNSDAALGYAEALTRSSDPEDNRRGGELLRRLVSRDHTDIRVLSLYAFSAFEQQRFDEAVAAW
EMMLKLLPAGDARRAVIERSIRLAQEK
>Mature_347_residues
MRLLPGMVMLMLALVISGSARATTDVMPFKDEAQEQQFRQLTEQLRCPKCQNNSIADSNAMIATDMRRRVYDLMQEGKSR
QEIIDYMVARYGNFVTYDPPLTPLTVLLWVLPLAAIVAGGWIIVARTRRRVRIRQDVLADAIPAAGPRAGVGVYLPGVVM
ALVVAAISYSQTGSYQQVRAWQQATAQTPGLLARALDPQAQPLNEEEMARLALGLRTRLQNDAGNVEGWLMLGRIGMVLG
NAGTATGAYANACRLDPKNSDAALGYAEALTRSSDPEDNRRGGELLRRLVSRDHTDIRVLSLYAFSAFEQQRFDEAVAAW
EMMLKLLPAGDARRAVIERSIRLAQEK

Specific function: May be required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG4235

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1788522, Length=347, Percent_Identity=73.7752161383285, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1790512, Length=65, Percent_Identity=52.3076923076923, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005616
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF03918 CcmH [H]

EC number: NA

Molecular weight: Translated: 38332; Mature: 38332

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLPGMVMLMLALVISGSARATTDVMPFKDEAQEQQFRQLTEQLRCPKCQNNSIADSNA
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
MIATDMRRRVYDLMQEGKSRQEIIDYMVARYGNFVTYDPPLTPLTVLLWVLPLAAIVAGG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCC
WIIVARTRRRVRIRQDVLADAIPAAGPRAGVGVYLPGVVMALVVAAISYSQTGSYQQVRA
EEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
WQQATAQTPGLLARALDPQAQPLNEEEMARLALGLRTRLQNDAGNVEGWLMLGRIGMVLG
HHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
NAGTATGAYANACRLDPKNSDAALGYAEALTRSSDPEDNRRGGELLRRLVSRDHTDIRVL
CCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
SLYAFSAFEQQRFDEAVAAWEMMLKLLPAGDARRAVIERSIRLAQEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLLPGMVMLMLALVISGSARATTDVMPFKDEAQEQQFRQLTEQLRCPKCQNNSIADSNA
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
MIATDMRRRVYDLMQEGKSRQEIIDYMVARYGNFVTYDPPLTPLTVLLWVLPLAAIVAGG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCC
WIIVARTRRRVRIRQDVLADAIPAAGPRAGVGVYLPGVVMALVVAAISYSQTGSYQQVRA
EEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
WQQATAQTPGLLARALDPQAQPLNEEEMARLALGLRTRLQNDAGNVEGWLMLGRIGMVLG
HHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
NAGTATGAYANACRLDPKNSDAALGYAEALTRSSDPEDNRRGGELLRRLVSRDHTDIRVL
CCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
SLYAFSAFEQQRFDEAVAAWEMMLKLLPAGDARRAVIERSIRLAQEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503; 7635817 [H]