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The map label for this gene is rhmA

Identifier: 194736883

GI number: 194736883

Start: 2401941

End: 2402744

Strand: Reverse

Name: rhmA

Synonym: SeSA_A2517

Alternate gene names: 194736883

Gene position: 2402744-2401941 (Counterclockwise)

Preceding gene: 194735224

Following gene: 194736303

Centisome position: 51.02

GC content: 54.73

Gene sequence:

>804_bases
ATGAACGCATTGTTATCAAATCCTTTTAAAGAAGGATTACGTAAAGGGGATACGCAAATTGGTTTGTGGCTCAGTTCAAC
CACCTCTTATATGGCGGAGATTGCGGCGACGTCGGGTTATGACTGGTTGTTAATAGATGGCGAGCACGCGCCTAATACGG
TGCAGGACTTGTATCATCAGTTACAGGCCATCGCCCCATACGCCAGCCAGCCGGTGATTCGCCCGATCGAGGGAAGTAAA
GCGCTCATTAAACAGGTACTGGACATCGGGGCGCAAACGCTACTGATCCCGATGGTTGACACCGCAGAACAGGCGCGCCA
GGTCGTTTCCGCTACCCGATACCCGCCGTTGGGGCAACGAGGCGTTGGCGCGAGCGTGGCGCGTGCGGCGCGCTGGGGGA
GAATCGACAACTATATGGCACAGGCCAATGAGTCGCTCTGCCTGTTGGTGCAGGTTGAAAGCAAAGTGGCGCTGGAAAAC
CTTGACGCGATTCTGGAGGTTGAAGGCATTGATGGCGTCTTTATCGGTCCGGCAGATCTCTCTGCTTCATTGGGTTACCC
CGATAATGCCGGACACCCGGAAGTGCAGCGGATCATTGAAGCGTGTATTTATCGTATTCGCGCCGCCGGAAAAGCGGCGG
GTTTTTTGGCGGTCGATCCGGCAATGGCGCAGAAATGTCTGGCGTGGGGCGCGAATTTTGTCGCGGTCGGGGTAGATACG
ATGCTCTACACCGAGGCGCTGGACAGCAGGTTGGCGATGTTTAAATCTGTTCAGTCAGTAAGCACGGCAAAACGTAGTTA
TTGA

Upstream 100 bases:

>100_bases
ATCATTGGCTCATTAATTATCTTCACGCTGAGCGTTAATCGTCCGGTGGCGCAATCCGGCGCTGCGCATCATTAATCTTA
TCTACGTTGTAAGGATCGCT

Downstream 100 bases:

>100_bases
GAAAAATGCCGGATGGCACGTATGCCTTACGCGTGCGTTTTAGCGCCAATCGGTATAGTCTGGCAATACGTCAGGAGGTC
TGCGCGATGATGGCGCTAAA

Product: putative aldolase

Products: NA

Alternate protein names: KDR aldolase; 2-dehydro-3-deoxyrhamnonate aldolase

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MNALLSNPFKEGLRKGDTQIGLWLSSTTSYMAEIAATSGYDWLLIDGEHAPNTVQDLYHQLQAIAPYASQPVIRPIEGSK
ALIKQVLDIGAQTLLIPMVDTAEQARQVVSATRYPPLGQRGVGASVARAARWGRIDNYMAQANESLCLLVQVESKVALEN
LDAILEVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIEACIYRIRAAGKAAGFLAVDPAMAQKCLAWGANFVAVGVDT
MLYTEALDSRLAMFKSVQSVSTAKRSY

Sequences:

>Translated_267_residues
MNALLSNPFKEGLRKGDTQIGLWLSSTTSYMAEIAATSGYDWLLIDGEHAPNTVQDLYHQLQAIAPYASQPVIRPIEGSK
ALIKQVLDIGAQTLLIPMVDTAEQARQVVSATRYPPLGQRGVGASVARAARWGRIDNYMAQANESLCLLVQVESKVALEN
LDAILEVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIEACIYRIRAAGKAAGFLAVDPAMAQKCLAWGANFVAVGVDT
MLYTEALDSRLAMFKSVQSVSTAKRSY
>Mature_267_residues
MNALLSNPFKEGLRKGDTQIGLWLSSTTSYMAEIAATSGYDWLLIDGEHAPNTVQDLYHQLQAIAPYASQPVIRPIEGSK
ALIKQVLDIGAQTLLIPMVDTAEQARQVVSATRYPPLGQRGVGASVARAARWGRIDNYMAQANESLCLLVQVESKVALEN
LDAILEVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIEACIYRIRAAGKAAGFLAVDPAMAQKCLAWGANFVAVGVDT
MLYTEALDSRLAMFKSVQSVSTAKRSY

Specific function: Catalyzes the reversible retro-aldol cleavage of 2-keto- 3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde

COG id: COG3836

COG function: function code G; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily

Homologues:

Organism=Escherichia coli, GI1788578, Length=267, Percent_Identity=87.2659176029963, Blast_Score=480, Evalue=1e-137,
Organism=Escherichia coli, GI1789514, Length=254, Percent_Identity=43.3070866141732, Blast_Score=218, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RHMA_SALA4 (B5EZG8)

Other databases:

- EMBL:   CP001138
- RefSeq:   YP_002147245.1
- ProteinModelPortal:   B5EZG8
- SMR:   B5EZG8
- PRIDE:   B5EZG8
- GeneID:   6792600
- GenomeReviews:   CP001138_GR
- KEGG:   sea:SeAg_B2425
- HOGENOM:   HBG747616
- OMA:   SIGSELH
- ProtClustDB:   PRK10128
- HAMAP:   MF_01290
- InterPro:   IPR005000
- InterPro:   IPR015813
- Gene3D:   G3DSA:3.20.20.60

Pfam domain/function: PF03328 HpcH_HpaI; SSF51621 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 28727; Mature: 28727

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: ACT_SITE 49-49 BINDING 151-151 BINDING 178-178 BINDING 179-179

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALLSNPFKEGLRKGDTQIGLWLSSTTSYMAEIAATSGYDWLLIDGEHAPNTVQDLYHQ
CCCCCCCHHHHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
LQAIAPYASQPVIRPIEGSKALIKQVLDIGAQTLLIPMVDTAEQARQVVSATRYPPLGQR
HHHHCCCCCCCCEECCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCC
GVGASVARAARWGRIDNYMAQANESLCLLVQVESKVALENLDAILEVEGIDGVFIGPADL
CCCHHHHHHHHHCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHEEECCCCEEEECCCCC
SASLGYPDNAGHPEVQRIIEACIYRIRAAGKAAGFLAVDPAMAQKCLAWGANFVAVGVDT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHCCCEEEEHHHH
MLYTEALDSRLAMFKSVQSVSTAKRSY
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNALLSNPFKEGLRKGDTQIGLWLSSTTSYMAEIAATSGYDWLLIDGEHAPNTVQDLYHQ
CCCCCCCHHHHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
LQAIAPYASQPVIRPIEGSKALIKQVLDIGAQTLLIPMVDTAEQARQVVSATRYPPLGQR
HHHHCCCCCCCCEECCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCC
GVGASVARAARWGRIDNYMAQANESLCLLVQVESKVALENLDAILEVEGIDGVFIGPADL
CCCHHHHHHHHHCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHEEECCCCEEEECCCCC
SASLGYPDNAGHPEVQRIIEACIYRIRAAGKAAGFLAVDPAMAQKCLAWGANFVAVGVDT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHCCCEEEEHHHH
MLYTEALDSRLAMFKSVQSVSTAKRSY
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA