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The map label for this gene is rhmT [H]

Identifier: 194735224

GI number: 194735224

Start: 2402770

End: 2404059

Strand: Reverse

Name: rhmT [H]

Synonym: SeSA_A2518

Alternate gene names: 194735224

Gene position: 2404059-2402770 (Counterclockwise)

Preceding gene: 194736010

Following gene: 194736883

Centisome position: 51.05

GC content: 53.88

Gene sequence:

>1290_bases
ATGAGCATCACTTTACTTGACGGCGTAGTGAAGAAAAACCGCGCACGTTTAATTCCTTTTATGTTGGCACTGTATGTACT
GGCGTTTCTGGATCGTTCAAATATTGGTTTTGCCAAAGAGACCTATCAGATAGATACCGGGCTAAGTAATGAAGCCTACG
CGCTAGGGGCCGGTATTTTCTTTGTGGTTTACGCTTTCCTTGGCGTACCGGCTAACCTGCTGATGCGCAAATTTGGCGCA
AGAACCTGGATCGGCACGACTACCCTGCTGTGGGGCTTTCTCTCTGCTGCGATGGCCTGGGCGGATAGTGAAGCAAAATT
CCTGATAATCCGCACGCTATTGGGCGCGGCGGAGGCTGGATTTTTCCCCGGCATGATCTATCTAACTTCACAATGGTTCC
CGCAGCGTAACCGTGCCAGCATTATGGGGCTATTTTATATGGGCGCGCCGCTGGCGTTAACGTTGGGTTCGCCGCTCTCC
GGCGCTCTGCTGGAGATGCATGGTTTTATGGGGCACCCGGGATGGTTCTGGATGTTCGTTATCGAAGGCCTACTGGCGAT
TGGCGCAGGGATATTCACCTTTTTCTGGCTTGATGACACTCCGCAGCAGGCGCGTTTTCTTAGCCTGGAAGAAAAGAACG
CGCTTATCAGGCAACTGGCGAGCGAAGAAGAGAAAAAGGTCACGTCAAGGCTTGCGGATGCGCTGCGTAATGGACGCGTC
TGGCAACTGGCTATTATTTATCTGACGATTCAGGTGGCGGTATACGGACTCATCTTTTTCCTGCCGACCCAGGTTGCCGC
GCTATTGGGCACTAAAGTGGGCTTTACCGCTTCGGTGGTAACAGCGGTTCCCTGGATGGCGGCTTTGCTTGGCACATGGC
TTATTCCTCGCTACTCCGACCGTACCGGCGATCGTCGTAACGTTGCGGCAGTGACGCTACTGGCTGCGGGCATTGGCATT
GGCCTGTCAGGTCTGGTTTCTCCGGTGCTTGCTATTCTGGCGCTCTGTGTTGCAGCAGTAGGATTTATTGCCGTTCAGCC
CGTATTCTGGACCATGCCAACGCAGCTACTTTCCGGTACGGCTCTGGCGGCAGGAATTGGTTTCGTTAATCTGTTTGGCG
CTGTGGGCGGTTTTATTGCCCCAATTCTGCGCGTAAAAGCGGAAACGTTGTTTGCCAGCGATGCGGCGGGCCTGCTGACG
CTGGCCGGAGTCGCCATCATTGGCTCATTAATTATCTTCACGCTGAGCGTTAATCGTCCGGTGGCGCAATCCGGCGCTGC
GCATCATTAA

Upstream 100 bases:

>100_bases
GAGCTTAACCGTGACTGTCACTTGAAACGCCCTTATAGCCACTAATAACTCGTGCGTTGCCTTTGTACGGCAACGCCCTC
ATCCTGTTGAGGATATTGCT

Downstream 100 bases:

>100_bases
TCTTATCTACGTTGTAAGGATCGCTATGAACGCATTGTTATCAAATCCTTTTAAAGAAGGATTACGTAAAGGGGATACGC
AAATTGGTTTGTGGCTCAGT

Product: transporter major facilitator family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSITLLDGVVKKNRARLIPFMLALYVLAFLDRSNIGFAKETYQIDTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKFGA
RTWIGTTTLLWGFLSAAMAWADSEAKFLIIRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLS
GALLEMHGFMGHPGWFWMFVIEGLLAIGAGIFTFFWLDDTPQQARFLSLEEKNALIRQLASEEEKKVTSRLADALRNGRV
WQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFTASVVTAVPWMAALLGTWLIPRYSDRTGDRRNVAAVTLLAAGIGI
GLSGLVSPVLAILALCVAAVGFIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAVGGFIAPILRVKAETLFASDAAGLLT
LAGVAIIGSLIIFTLSVNRPVAQSGAAHH

Sequences:

>Translated_429_residues
MSITLLDGVVKKNRARLIPFMLALYVLAFLDRSNIGFAKETYQIDTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKFGA
RTWIGTTTLLWGFLSAAMAWADSEAKFLIIRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLS
GALLEMHGFMGHPGWFWMFVIEGLLAIGAGIFTFFWLDDTPQQARFLSLEEKNALIRQLASEEEKKVTSRLADALRNGRV
WQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFTASVVTAVPWMAALLGTWLIPRYSDRTGDRRNVAAVTLLAAGIGI
GLSGLVSPVLAILALCVAAVGFIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAVGGFIAPILRVKAETLFASDAAGLLT
LAGVAIIGSLIIFTLSVNRPVAQSGAAHH
>Mature_428_residues
SITLLDGVVKKNRARLIPFMLALYVLAFLDRSNIGFAKETYQIDTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKFGAR
TWIGTTTLLWGFLSAAMAWADSEAKFLIIRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLSG
ALLEMHGFMGHPGWFWMFVIEGLLAIGAGIFTFFWLDDTPQQARFLSLEEKNALIRQLASEEEKKVTSRLADALRNGRVW
QLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFTASVVTAVPWMAALLGTWLIPRYSDRTGDRRNVAAVTLLAAGIGIG
LSGLVSPVLAILALCVAAVGFIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAVGGFIAPILRVKAETLFASDAAGLLTL
AGVAIIGSLIIFTLSVNRPVAQSGAAHH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=386, Percent_Identity=24.8704663212435, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87082071, Length=429, Percent_Identity=91.3752913752914, Blast_Score=790, Evalue=0.0,
Organism=Escherichia coli, GI2367193, Length=441, Percent_Identity=23.3560090702948, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082320, Length=423, Percent_Identity=22.4586288416076, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI2367379, Length=187, Percent_Identity=25.668449197861, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789152, Length=412, Percent_Identity=23.3009708737864, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71991448, Length=338, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71991453, Length=338, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=215, Percent_Identity=27.906976744186, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323032, Length=215, Percent_Identity=27.906976744186, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321698, Length=323, Percent_Identity=24.1486068111455, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322612, Length=274, Percent_Identity=22.992700729927, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI20130167, Length=360, Percent_Identity=25.2777777777778, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46020; Mature: 45889

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITLLDGVVKKNRARLIPFMLALYVLAFLDRSNIGFAKETYQIDTGLSNEAYALGAGIF
CEEEHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCCHHHHHHHHH
FVVYAFLGVPANLLMRKFGARTWIGTTTLLWGFLSAAMAWADSEAKFLIIRTLLGAAEAG
HHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
FFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLSGALLEMHGFMGHPGWFWMFV
CCCCHHEEECCCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCHHHHHHH
IEGLLAIGAGIFTFFWLDDTPQQARFLSLEEKNALIRQLASEEEKKVTSRLADALRNGRV
HHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
WQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFTASVVTAVPWMAALLGTWLIPRYSD
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
RTGDRRNVAAVTLLAAGIGIGLSGLVSPVLAILALCVAAVGFIAVQPVFWTMPTQLLSGT
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALAAGIGFVNLFGAVGGFIAPILRVKAETLFASDAAGLLTLAGVAIIGSLIIFTLSVNRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCC
VAQSGAAHH
HHCCCCCCC
>Mature Secondary Structure 
SITLLDGVVKKNRARLIPFMLALYVLAFLDRSNIGFAKETYQIDTGLSNEAYALGAGIF
EEEHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCCHHHHHHHHH
FVVYAFLGVPANLLMRKFGARTWIGTTTLLWGFLSAAMAWADSEAKFLIIRTLLGAAEAG
HHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
FFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLSGALLEMHGFMGHPGWFWMFV
CCCCHHEEECCCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCHHHHHHH
IEGLLAIGAGIFTFFWLDDTPQQARFLSLEEKNALIRQLASEEEKKVTSRLADALRNGRV
HHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
WQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFTASVVTAVPWMAALLGTWLIPRYSD
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
RTGDRRNVAAVTLLAAGIGIGLSGLVSPVLAILALCVAAVGFIAVQPVFWTMPTQLLSGT
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALAAGIGFVNLFGAVGGFIAPILRVKAETLFASDAAGLLTLAGVAIIGSLIIFTLSVNRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCC
VAQSGAAHH
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]